Reconstructing uniformly attenuated rotating slant-hole SPECT projection data using the DBH method.

Abstract:

:This work applies a previously developed analytical algorithm to the reconstruction problem in a rotating multi-segment slant-hole (RMSSH) SPECT system. The RMSSH collimator has greater detection efficiency than the parallel-hole collimator with comparable spatial resolution at the expense of limited common volume-of-view (CVOV) and is therefore suitable for detecting low-contrast lesions in breast, cardiac and brain imaging. The absorption of gamma photons in both the human breast and brain can be assu- med to follow an exponential rule with a constant attenuation coefficient. In this work, the RMSSH SPECT data of a digital NCAT phantom with breast attachment are modeled as the uniformly attenuated Radon transform of the activity distribution. These data are reconstructed using an analytical algorithm called the DBH method, which is an acronym for the procedure of differentiation backprojection followed by a finite weighted inverse Hilbert transform. The projection data are first differentiated along a specific direction in the projection space and then backprojected to the image space. The result from this first step is equal to a one-dimensional finite weighted Hilbert transform of the object; this transform is then numerically inverted to obtain the reconstructed image. With the limited CVOV of the RMSSH collimator, the detector captures gamma photon emissions from the breast and from parts of the torso. The simulation results show that the DBH method is capable of exactly reconstructing the activity within a well-defined region-of-interest (ROI) within the breast if the activity is confined to the breast or if the activity outside the CVOV is uniformly attenuated for each measured projection, while a conventional filtered backprojection algorithm only reconstructs the high frequency components of the activity function in the same geometry.

journal_name

Phys Med Biol

authors

Huang Q,Xu J,Tsui BM,Gullberg GT

doi

10.1088/0031-9155/54/13/024

subject

Has Abstract

pub_date

2009-07-07 00:00:00

pages

4325-39

issue

13

eissn

0031-9155

issn

1361-6560

pii

S0031-9155(09)04275-4

journal_volume

54

pub_type

杂志文章
  • A framework for organ dose estimation in x-ray angiography and interventional radiology based on dose-related data in DICOM structured reports.

    abstract::Although interventional x-ray angiography (XA) procedures involve relatively high radiation doses that can lead to deterministic tissue reactions in addition to stochastic effects, convenient and accurate estimation of absorbed organ doses has traditionally been out of reach. This has mainly been due to the absence of...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/61/8/3063

    authors: Omar A,Bujila R,Fransson A,Andreo P,Poludniowski G

    更新日期:2016-04-21 00:00:00

  • Two-dimensional and quasi-three-dimensional dosimetry of hadron and photon beams with the Magic Cube and the Pixel Ionization Chamber.

    abstract::Two detectors for fast two-dimensional (2D) and quasi-three-dimensional (quasi-3D) verification of the dose delivered by radiotherapy beams have been developed at University and Istituto Nazionale di Fisica Nucleare (INFN) of Torino. The Magic Cube is a stack of strip-segmented ionization chambers interleaved with wat...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/49/16/017

    authors: Cirio R,Garelli E,Schulte R,Amerio S,Boriano A,Bourhaleb F,Coutrakon G,Donetti M,Giordanengo S,Koss P,Madon E,Marchetto F,Nastasi U,Peroni C,Santuari D,Sardo A,Scielzo G,Stasi M,Trevisiol E

    更新日期:2004-08-21 00:00:00

  • Monte Carlo optimization of a microbeam collimator design for use on the small animal radiation research platform (SARRP).

    abstract::Microbeam radiation therapy (MRT) is a pre-clinical, spatially-fractionated treatment modality noted for its ability to achieve a large differential response between normal and tumoral tissues. In the present study, TOPAS Monte Carlo (MC) simulations were used to optimize the design of a compact, affordable multi-slit...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aad7e2

    authors: Esplen NM,Chergui L,Johnstone CD,Bazalova-Carter M

    更新日期:2018-08-29 00:00:00

  • Improved correction for the tissue fraction effect in lung PET/CT imaging.

    abstract::Recently, there has been an increased interest in imaging different pulmonary disorders using PET techniques. Previous work has shown, for static PET/CT, that air content in the lung influences reconstructed image values and that it is vital to correct for this 'tissue fraction effect' (TFE). In this paper, we extend ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/18/7387

    authors: Holman BF,Cuplov V,Millner L,Hutton BF,Maher TM,Groves AM,Thielemans K

    更新日期:2015-09-21 00:00:00

  • Cascaded systems analysis of anatomic noise in digital mammography and dual-energy digital mammography.

    abstract::In x-ray based imaging of the breast, contrast between fibroglandular (Fg) tissue and adipose (Ad) tissue is a source of anatomic noise. The goal of this work was to validate by simulation and experiment a mathematical framework for modelling the Fg component of anatomic noise in digital mammograpy (DM) and dual-energ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab3fcd

    authors: Tanguay J,Lalonde R,Bjarnason TA,Yang CJ

    更新日期:2019-10-23 00:00:00

  • Evaluation of nonuniform field exposures with coupling factors.

    abstract::In this study, the safety compliance for nonuniform field exposures is discussed using coupling factor concepts. The coupling factor, which is defined in the International Electrotechnical Commission 62311 standard, is extended to consider the effects of harmonics and also to apply to the specific absorption rate (for...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/20/8129

    authors: Sunohara T,Hirata A,Laakso I,De Santis V,Onishi T

    更新日期:2015-10-21 00:00:00

  • Filtered back-projection reconstruction for attenuation proton CT along most likely paths.

    abstract::This work investigates the attenuation of a proton beam to reconstruct the map of the linear attenuation coefficient of a material which is mainly caused by the inelastic interactions of protons with matter. Attenuation proton computed tomography (pCT) suffers from a poor spatial resolution due to multiple Coulomb sca...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/61/9/3258

    authors: Quiñones CT,Létang JM,Rit S

    更新日期:2016-05-07 00:00:00

  • Robust radiation therapy optimization using simulated treatment courses for handling deformable organ motion.

    abstract::We describe a radiation therapy treatment plan optimization method that explicitly considers the effects of interfraction organ motion through optimization on the clinical target volume (CTV), and investigate how it compares to conventional planning using a planning target volume (PTV). The method uses simulated treat...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/abd591

    authors: Fredriksson A,Engwall E,Andersson B

    更新日期:2020-12-21 00:00:00

  • Experimental verification of numerical simulations of cryosurgery with application to computerized planning.

    abstract::As a part of an ongoing effort to develop computerized planning tools for cryosurgery, an experimental study has been conducted to verify a recently developed numerical technique for bioheat transfer simulations. Experiments were performed on gelatin solution as a phantom material, using proprietary liquid-nitrogen cr...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/52/15/013

    authors: Rossi MR,Rabin Y

    更新日期:2007-08-07 00:00:00

  • Using surface markers for MRI guided breast conserving surgery: a feasibility survey.

    abstract::Breast MRI is frequently performed prior to breast conserving surgery in order to assess the location and extent of the lesion. Ideally, the surgeon should also be able to use the image information during surgery to guide the excision and this requires that the MR image is co-registered to conform to the patient's pos...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/59/7/1589

    authors: Ebrahimi M,Siegler P,Modhafar A,Holloway CM,Plewes DB,Martel AL

    更新日期:2014-04-07 00:00:00

  • Motion-induced dose artifacts in helical tomotherapy.

    abstract::Tumor motion is a particular concern for a complex treatment modality such as helical tomotherapy, where couch position, gantry rotation and MLC leaf opening all change with time. In the present study, we have investigated the impact of tumor motion for helical tomotherapy, which could result in three distinct motion-...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/54/19/004

    authors: Kim B,Chen J,Kron T,Battista J

    更新日期:2009-10-07 00:00:00

  • A comparison of direct reconstruction algorithms in proton computed tomography.

    abstract::Several direct algorithms have been proposed to take into account the non-linear path of protons in the reconstruction of a proton CT (pCT) image. This paper presents a comparison between five of them, in terms of spatial resolution and relative stopping power (RSP) accuracy. Our comparison includes (1) a distance-dri...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab7d53

    authors: Khellaf F,Krah N,Létang JM,Collins-Fekete CA,Rit S

    更新日期:2020-06-01 00:00:00

  • Monte Carlo correction factors for a Farmer 0.6 cm3 ion chamber dose measurement in the build-up region of the 6 MV clinical beam.

    abstract::Reference dosimetry of photon fields is a well-established subject and currently available protocols (such as the IAEA TRS-398 and AAPM TG-51) provide methods for converting the ionization chamber (IC) reading into dose to water, provided reference conditions of charged particle equilibrium (CPE) are fulfilled. But th...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/51/6/011

    authors: Pena J,Sánchez-Doblado F,Capote R,Terrón JA,Gómez F

    更新日期:2006-03-21 00:00:00

  • An analysis of breast motion using high-frequency, dense surface points captured by an optical sensor during radiotherapy treatment delivery.

    abstract::Patient motion is an important factor affecting the quality of external beam radiotherapy in breast patients. We analyse the motion of a dense set of surface points on breast patients throughout their treatment schedule to assess the magnitude and stability of motion, in particular, with respect to breast volume. We u...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/54/21/005

    authors: Price GJ,Sharrock PJ,Marchant TE,Parkhurst JM,Burton D,Jain P,Price P,Moore CJ

    更新日期:2009-11-07 00:00:00

  • A low-count reconstruction algorithm for Compton-based prompt gamma imaging.

    abstract::The Compton camera is an imaging device which has been proposed to detect prompt gammas (PGs) produced by proton-nuclear interactions within tissue during proton beam irradiation. Compton-based PG imaging has been developed to verify proton ranges because PG rays, particularly characteristic ones, have strong correlat...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aab737

    authors: Huang HM,Liu CC,Jan ML,Lee MW

    更新日期:2018-04-19 00:00:00

  • Modelling individual temperature profiles from an isolated perfused bovine tongue.

    abstract::To predict the temperature distribution during hyperthermia treatments a thermal model that accounts for the thermal effect of blood flow is mandatory. The DIscrete VAsculature (DIVA) thermal model developed at our department is able to do so; geometrically described vessels are handled individually and the remaining ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/45/3/314

    authors: Raaymakers BW,Crezee J,Lagendijk JJ

    更新日期:2000-03-01 00:00:00

  • Viscoelastic characterization of thin tissues using acoustic radiation force and model-based inversion.

    abstract::By means of the viscoelastodynamic model for a two-layer solid-fluid system and a detailed account of the locally induced acoustic radiation force, a rational analytical and computational framework is established for the viscoelastic characterization of thin tissues from high-frequency ultrasound (HFUS) measurements. ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/54/13/009

    authors: Guzina BB,Tuleubekov K,Liu D,Ebbini ES

    更新日期:2009-07-07 00:00:00

  • Sensitivity study of the microdosimetric kinetic model parameters for carbon ion radiotherapy.

    abstract::In carbon ion therapy treatment planning, the relative biological effectiveness (RBE) is accounted for by optimization of the RBE-weighted dose (biological dose). The RBE calculation methods currently applied clinically in carbon ion therapy are derived from the microdosimetric kinetic model (MKM) in Japan and the loc...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aae8b4

    authors: Dahle TJ,Magro G,Ytre-Hauge KS,Stokkevåg CH,Choi K,Mairani A

    更新日期:2018-11-12 00:00:00

  • Monte Carlo simulation and dosimetric verification of radiotherapy beam modifiers.

    abstract::Monte Carlo simulation of beam modifiers such as physical wedges and compensating filters has been performed with a rectilinear voxel geometry module. A modified version of the EGS4/DOSXYZ code has been developed for this purpose. The new implementations have been validated against the BEAM Monte Carlo code using its ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/46/11/316

    authors: Spezi E,Lewis DG,Smith CW

    更新日期:2001-11-01 00:00:00

  • Investigation of patient, tumour and treatment variables affecting residual motion for respiratory-gated radiotherapy.

    abstract::Respiratory gating can reduce the apparent respiratory motion during imaging and treatment; however, residual motion within the gating window remains. Respiratory training can improve respiratory reproducibility and, therefore, the efficacy of respiratory-gated radiotherapy. This study was conducted to determine wheth...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/51/20/015

    authors: George R,Ramakrishnan V,Siebers JV,Chung TD,Keall PJ

    更新日期:2006-10-21 00:00:00

  • Monitor unit calculation on the beam axis of open and wedged asymmetric high-energy photon beams.

    abstract::An ESTRO booklet and a report of the Netherlands Commission on Radiation Dosimetry have been published recently describing empirical methods for monitor unit (MU) calculations in symmetrical high-energy photon beams. Both documents support the same basic ideas; firstly the separation of head scatter and volume scatter...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/44/12/310

    authors: Georg D

    更新日期:1999-12-01 00:00:00

  • Fast calibration of SPECT monolithic scintillation detectors using un-collimated sources.

    abstract::Monolithic scintillation detectors for positron emission tomography and single-photon emission computed tomography (SPECT) imaging have many advantages over pixelated detectors. The use of monolithic crystals allows for reducing the scintillator cost per unit volume and increasing the sensitivity along with the energy...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/58/14/4807

    authors: España S,Deprez K,Van Holen R,Vandenberghe S

    更新日期:2013-07-21 00:00:00

  • Feasibility of replacing patient specific cutouts with a computer-controlled electron multileaf collimator.

    abstract::A motorized electron multileaf collimator (eMLC) was developed as an add-on device to the Varian linac for delivery of advanced electron beam therapy. It has previously been shown that electron beams collimated by an eMLC have very similar penumbra to those collimated by applicators and cutouts. Thus, manufacturing pa...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/58/16/5653

    authors: Eldib A,Jin L,Li J,Ma CM

    更新日期:2013-08-21 00:00:00

  • Assessment of the effects of pixel loss on image quality in direct digital radiography.

    abstract::Modern digital radiographic 'flat panel' detectors can exhibit a progressive form of image degradation arising from non-functioning pixels. The effect of these 'dead pixels' on the quantitive image quality measures of modulation transfer function (MTF), noise power spectrum (NPS) and detective quantum efficiency (DQE)...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/49/6/008

    authors: Padgett R,Kotre CJ

    更新日期:2004-03-21 00:00:00

  • Accelerated time-of-flight (TOF) PET image reconstruction using TOF bin subsetization and TOF weighting matrix pre-computation.

    abstract::Time-of-flight (TOF) positron emission tomography (PET) technology has recently regained popularity in clinical PET studies for improving image quality and lesion detectability. Using TOF information, the spatial location of annihilation events is confined to a number of image voxels along each line of response, there...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/61/3/1309

    authors: Mehranian A,Kotasidis F,Zaidi H

    更新日期:2016-02-07 00:00:00

  • Analytic treatment of resolution precision in electronically collimated SPECT imaging involving multiple-interaction gamma rays.

    abstract::The widely applied single-interaction analytic expression characterizing the energy resolution component of the angular resolution precision for an electronically collimated point source is extended to include multiple-interaction Compton scatter sequences as well as sequences terminated by photoelectric absorption. T...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/43/10/021

    authors: Durkee JW Jr,Antich PP,Tsyganov EN,Constantinescu A,Kulkarni PV,Smith BJ,Arbique GM,Lewis MA,Nguyen T,Raheja A,Thambi G,Parkey RW

    更新日期:1998-10-01 00:00:00

  • Rotational IMRT delivery using a digital linear accelerator in very high dose rate 'burst mode'.

    abstract::Recently, there has been a resurgence of interest in arc-based IMRT, through the use of 'conventional' multileaf collimator (MLC) systems that can treat large tumor volumes in a single, or very few pass(es) of the gantry. Here we present a novel 'burst mode' modulated arc delivery approach, wherein 2000 monitor units ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/56/7/002

    authors: Salter BJ,Sarkar V,Wang B,Shukla H,Szegedi M,Rassiah-Szegedi P

    更新日期:2011-04-07 00:00:00

  • Three-dimensional performance of a small-diameter positron emission tomograph.

    abstract::Recently, the initial 2D physical characterization of a small-diameter positron emission tomograph, designed specifically for scanning of small laboratory animals, was reported. The physical characteristics of the tomograph operating in 3D mode have now been measured and compared to those obtained in 2D mode. In 3D, t...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/42/2/010

    authors: Bloomfield PM,Myers R,Hume SP,Spinks TJ,Lammertsma AA,Jones T

    更新日期:1997-02-01 00:00:00

  • Assessment of the accuracy of an MCNPX-based Monte Carlo simulation model for predicting three-dimensional absorbed dose distributions.

    abstract::In recent years, the Monte Carlo method has been used in a large number of research studies in radiation therapy. For applications such as treatment planning, it is essential to validate the dosimetric accuracy of the Monte Carlo simulations in heterogeneous media. The AAPM Report no 105 addresses issues concerning cl...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/53/16/016

    authors: Titt U,Sahoo N,Ding X,Zheng Y,Newhauser WD,Zhu XR,Polf JC,Gillin MT,Mohan R

    更新日期:2008-08-21 00:00:00

  • Tradeoffs of integrating real-time tracking into IGRT for prostate cancer treatment.

    abstract::This study investigated the integration of the Calypso real-time tracking system, based on implanted ferromagnetic transponders and a detector array, into the current process for image-guided radiation treatment (IGRT) of prostate cancer at our institution. The current IGRT process includes magnetic resonance imaging ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/54/17/N03

    authors: Zhu X,Bourland JD,Yuan Y,Zhuang T,O'Daniel J,Thongphiew D,Wu QJ,Das SK,Yoo S,Yin FF

    更新日期:2009-09-07 00:00:00