Monte Carlo correction factors for a Farmer 0.6 cm3 ion chamber dose measurement in the build-up region of the 6 MV clinical beam.

Abstract:

:Reference dosimetry of photon fields is a well-established subject and currently available protocols (such as the IAEA TRS-398 and AAPM TG-51) provide methods for converting the ionization chamber (IC) reading into dose to water, provided reference conditions of charged particle equilibrium (CPE) are fulfilled. But these protocols cannot deal with the build-up region, where the lack of CPE limits the applicability of the cavity theorems and so the chamber correction factors become depth dependent. By explicitly including the IC geometry in the Monte Carlo simulations, depth-dependent dose correction factors are calculated for a PTW 30001 0.6 cm(3) ion chamber in the build-up region of the 6 MV photon beam. The corrected percentage depth dose (PDD) agrees within 2% with that measured using the NACP 02 plane-parallel ion chamber in the build-up region at depths greater than 0.4 cm, where the Farmer chamber wall reaches the phantom surface.

journal_name

Phys Med Biol

authors

Pena J,Sánchez-Doblado F,Capote R,Terrón JA,Gómez F

doi

10.1088/0031-9155/51/6/011

subject

Has Abstract

pub_date

2006-03-21 00:00:00

pages

1523-32

issue

6

eissn

0031-9155

issn

1361-6560

pii

S0031-9155(06)06447-5

journal_volume

51

pub_type

杂志文章
  • Modelling the electrical properties of tissue as a porous medium.

    abstract::Models of the electrical properties of biological tissue have been the subject of many studies. These models have sought to explain aspects of the dielectric dispersion of tissue. This paper develops a mathematical model of the complex permittivity of tissue as a function of frequency f, in the range 10(4) < f < 10(7)...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/52/23/016

    authors: Smye SW,Evans CJ,Robinson MP,Sleeman BD

    更新日期:2007-12-07 00:00:00

  • Towards clinical application: prompt gamma imaging of passively scattered proton fields with a knife-edge slit camera.

    abstract::Prompt γ-ray imaging with a knife-edge shaped slit camera provides the possibility of verifying proton beam range in tumor therapy. Dedicated experiments regarding the characterization of the camera system have been performed previously. Now, we aim at implementing the prototype into clinical application of monitoring...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/61/22/7881

    authors: Priegnitz M,Barczyk S,Nenoff L,Golnik C,Keitz I,Werner T,Mein S,Smeets J,Vander Stappen F,Janssens G,Hotoiu L,Fiedler F,Prieels D,Enghardt W,Pausch G,Richter C

    更新日期:2016-11-21 00:00:00

  • Microdosimetric investigations on collimated fast neutron beams for radiation therapy: II. The problem of radiation quality and RBE.

    abstract::The correlation between radiation quality and cellular RBE of a mixed n-gamma field produced by a collimated fast-neutron beam produced by the bombardment of 14 MeV deuterons on Be in a water phantom is investigated. The microdosimetric parameters yF and YD are used for a physical description of the local distribution...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/26/1/006

    authors: Booz J,Fidorra J

    更新日期:1981-01-01 00:00:00

  • A novel geometry-dosimetry label fusion method in multi-atlas segmentation for radiotherapy: a proof-of-concept study.

    abstract::Multi-atlas segmentation (MAS) has been widely used to automate the delineation of organs at risk (OARs) for radiotherapy. Label fusion is a crucial step in MAS to cope with the segmentation variabilities among multiple atlases. However, most existing label fusion methods do not consider the potential dosimetric impac...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa5ed9

    authors: Chang J,Tian Z,Lu W,Gu X,Chen M,Jiang SB

    更新日期:2017-05-07 00:00:00

  • Simultaneous EEG-fMRI: evaluating the effect of the cabling configuration on the gradient artefact.

    abstract::EEG recordings made in combined EEG-fMRI studies are corrupted by gradient artefacts (GAs) resulting from the interaction of the EEG system with the time-varying magnetic field gradients used in MRI. The dominant contribution to the GA arises from interaction with the leads of the EEG cap and the human head, but artef...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/12/N241

    authors: Chowdhury ME,Mullinger KJ,Bowtell R

    更新日期:2015-06-21 00:00:00

  • Computed LET distributions in the build-up region of tissue for 14 MeV neutrons.

    abstract::Experimental radiobiological investigations of fast neutron beams involve irradiation of thin cell layers. The irradiation of cells is done either in free air or with a material such as graphite, TE plastic or bone-equivalent plastic covering the cells. This paper discusses the computed dose distributions in LET at sh...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/24/5/007

    authors: Bhatia DP,Nagarajan PS

    更新日期:1979-09-01 00:00:00

  • End-to-end tests using alanine dosimetry in scanned proton beams.

    abstract::This paper describes end-to-end test procedures as the last fundamental step of medical commissioning before starting clinical operation of the MedAustron synchrotron-based pencil beam scanning (PBS) therapy facility with protons. One in-house homogeneous phantom and two anthropomorphic heterogeneous (head and pelvis)...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aaac23

    authors: Carlino A,Gouldstone C,Kragl G,Traneus E,Marrale M,Vatnitsky S,Stock M,Palmans H

    更新日期:2018-02-26 00:00:00

  • Pre-treatment patient-specific stopping power by combining list-mode proton radiography and x-ray CT.

    abstract::The relative stopping power (RSP) uncertainty is the largest contributor to the range uncertainty in proton therapy. The purpose of this work was to develop a systematic method that yields accurate and patient-specific RSPs by combining (1) pre-treatment x-ray CT and (2) daily proton radiography of the patient. The me...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa7c42

    authors: Collins-Fekete CA,Brousmiche S,Hansen DC,Beaulieu L,Seco J

    更新日期:2017-08-03 00:00:00

  • Uncertainties in Monte Carlo-based absorbed dose calculations for an experimental benchmark.

    abstract::There is a need to verify the accuracy of general purpose Monte Carlo codes like EGSnrc, which are commonly employed for investigations of dosimetric problems in radiation therapy. A number of experimental benchmarks have been published to compare calculated values of absorbed dose to experimentally determined values....

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/19/7637

    authors: Renner F,Wulff J,Kapsch RP,Zink K

    更新日期:2015-10-07 00:00:00

  • Iterative reconstruction of SiPM light response functions in a square-shaped compact gamma camera.

    abstract::Compact gamma cameras with a square-shaped monolithic scintillator crystal and an array of silicon photomultipliers (SiPMs) are actively being developed for applications in areas such as small animal imaging, cancer diagnostics and radiotracer guided surgery. Statistical methods of position reconstruction, which are p...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa6029

    authors: Morozov A,Alves F,Marcos J,Martins R,Pereira L,Solovov V,Chepel V

    更新日期:2017-05-07 00:00:00

  • Automatic bladder segmentation on CBCT for multiple plan ART of bladder cancer using a patient-specific bladder model.

    abstract::In multiple plan adaptive radiotherapy (ART) strategies of bladder cancer, a library of plans corresponding to different bladder volumes is created based on images acquired in early treatment sessions. Subsequently, the plan for the smallest PTV safely covering the bladder on cone-beam CT (CBCT) is selected as the pla...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/57/12/3945

    authors: Chai X,van Herk M,Betgen A,Hulshof M,Bel A

    更新日期:2012-06-21 00:00:00

  • Dosimetry for the MRI accelerator: the impact of a magnetic field on the response of a Farmer NE2571 ionization chamber.

    abstract::The UMC Utrecht is constructing a 1.5 T MRI scanner integrated with a linear accelerator (Lagendijk et al 2008 Radiother. Oncol. 86 25-9). The goal of this device is to facilitate soft-tissue contrast based image-guided radiotherapy, in order to escalate the dose to the tumour while sparing surrounding normal tissues....

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/54/10/002

    authors: Meijsing I,Raaymakers BW,Raaijmakers AJ,Kok JG,Hogeweg L,Liu B,Lagendijk JJ

    更新日期:2009-05-21 00:00:00

  • Projection x-ray imaging with photon energy weighting: experimental evaluation with a prototype detector.

    abstract::The signal-to-noise ratio (SNR) in x-ray imaging can be increased using a photon counting detector which could allow for rejecting electronics noise and for weighting x-ray photons according to their energies. This approach, however, was not feasible for a long time because photon counting x-ray detectors with very hi...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/54/16/009

    authors: Shikhaliev PM

    更新日期:2009-08-21 00:00:00

  • Improving source detection and separation in a spatiotemporal Bayesian inference dipole analysis.

    abstract::Most existing spatiotemporal multi-dipole approaches for MEG/EEG source localization assume that the dipoles are active for the full time range being analysed. If the actual time range of activity of sources is significantly shorter than the time range being analysed, the detectability, localization and time-course de...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/51/10/004

    authors: Jun SC,George JS,Plis SM,Ranken DM,Schmidt DM,Wood CC

    更新日期:2006-05-21 00:00:00

  • Fast implementations of reconstruction-based scatter compensation in fully 3D SPECT image reconstruction.

    abstract::Accurate scatter compensation in SPECT can be performed by modelling the scatter response function during the reconstruction process. This method is called reconstruction-based scatter compensation (RBSC). It has been shown that RBSC has a number of advantages over other methods of compensating for scatter, but using ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/43/4/014

    authors: Kadrmas DJ,Frey EC,Karimi SS,Tsui BM

    更新日期:1998-04-01 00:00:00

  • A thermo-sensitive fluorescent agent based method for excitation light leakage rejection for fluorescence molecular tomography.

    abstract::Fluorescence molecular tomography (FMT) is widely used in preclinical oncology research. FMT is the only imaging technique able to provide 3D distribution of fluorescent probes within thick highly scattering media. However, its integration into clinical medicine has been hampered by its low spatial resolution caused b...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aaf96d

    authors: Nouizi F,Kwong TC,Ruiz J,Cho J,Chan YW,Ikemura K,Erkol H,Sampathkumaran U,Gulsen G

    更新日期:2019-01-22 00:00:00

  • Characterization of female breast lesions from multi-wavelength time-resolved optical mammography.

    abstract::Characterization of both malignant and benign lesions in the female breast is presented as the result of a clinical study that involved more than 190 subjects in the framework of the OPTIMAMM European project. All the subjects underwent optical mammography, by means of a multi-wavelength time-resolved mammograph, in t...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/50/11/004

    authors: Spinelli L,Torricelli A,Pifferi A,Taroni P,Danesini G,Cubeddu R

    更新日期:2005-06-07 00:00:00

  • Correction of proton resonance frequency shift temperature maps for magnetic field disturbances caused by breathing.

    abstract::Respiratory induced resonance offset (RIRO) is a periodic disturbance of a magnetic field due to breathing. Such disturbance handicaps the accuracy of the proton resonance frequency shift (PRFS) method of MRI temperature mapping in anatomies situated nearby the lungs and chest wall. In this work, we propose a method c...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/51/18/015

    authors: Shmatukha AV,Bakker CJ

    更新日期:2006-09-21 00:00:00

  • Measurement and correction of the effects of lag on contrast-detail test results in fluoroscopy.

    abstract::Persistence of the video signal between TV frames, an effect also known as image lag, can lead to anomalously good contrast-detail test results for fluoroscopy systems. In this practical paper, a simple method is described which quantifies lag in fluoroscopy systems and corrects for its effect on threshold contrast. A...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:

    authors: Marshall NW,Kotre CJ

    更新日期:2002-03-21 00:00:00

  • Reconstructing NMR images from projections under inhomogeneous magnetic field and non-linear field gradients.

    abstract::Both inhomogeneity in the main magnetic field and non-linearity in the gradient fields introduce errors in NMR images reconstructed from projections. It is found that the image artefacts caused by these two sources are separable. The inhomogeneous main field blurs the image while the nonlinear gradients distort the im...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/28/8/005

    authors: Lai CM

    更新日期:1983-08-01 00:00:00

  • Kill painting of hypoxic tumors with multiple ion beams.

    abstract::We report on a novel method for simultaneous biological optimization of treatment plans for hypoxic tumors using multiple ion species. Our previously introduced kill painting approach, where the overall cell killing is optimized on biologically heterogeneous targets, was expanded with the capability of handling differ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aafe40

    authors: Sokol O,Krämer M,Hild S,Durante M,Scifoni E

    更新日期:2019-02-08 00:00:00

  • Experimental pencil beam kernels derivation for 3D dose calculation in flattening filter free modulated fields.

    abstract::This paper presents a method to obtain the pencil-beam kernels that characterize a megavoltage photon beam generated in a flattening filter free (FFF) linear accelerator (linac) by deconvolution from experimental measurements at different depths. The formalism is applied to perform independent dose calculations in mod...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/61/1/50

    authors: Azcona JD,Barbés B,Wang L,Burguete J

    更新日期:2016-01-07 00:00:00

  • The effect of authentic metallic implants on the SAR distribution of the head exposed to 900, 1800 and 2450 MHz dipole near field.

    abstract::As the use of radiofrequency (RF) electromagnetic (EM) fields has increased along with increased use of wireless communication, the possible related health risks have also been widely discussed. One safety aspect is the interaction of medical implants and RF devices like mobile phones. In the literature, effects on ac...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/52/5/001

    authors: Virtanen H,Keshvari J,Lappalainen R

    更新日期:2007-03-07 00:00:00

  • Thermoluminescent response and relative efficiency of TLD-100 exposed to low-energy x-rays.

    abstract::The dose-response of LiF:Mg,Ti (TLD-100) exposed to 15 and 35 kVp (8.0 +/- 0.1 and 8.1 +/- 0.1 keV effective energy respectively) x-rays and 60Co gamma-rays has been measured in the dose interval from (1.2-5.4) x 10(3) Gy for x-rays, and from 0.14 to 850 Gy for gamma-rays. In both cases the total TL signal and glow cu...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/43/8/006

    authors: Gamboa-deBuen I,Buenfil AE,Ruiz CG,Rodríguez-Villafuerte M,Flores A,Brandan ME

    更新日期:1998-08-01 00:00:00

  • Optimization of the artificial urinary sphincter: modelling and experimental validation.

    abstract::The artificial urinary sphincter should be long enough to prevent strangulation effects of the urethral tissue and short enough to avoid the improper dissection of the surrounding tissue. To optimize the sphincter length, the empirical three-parameter urethra compression model is proposed based on the mechanical prope...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/51/5/023

    authors: Marti F,Leippold T,John H,Blunschi N,Müller B

    更新日期:2006-03-07 00:00:00

  • Significance of background optical properties, time-resolved information and optode arrangement in diffuse optical imaging of term neonates.

    abstract::The significance of accurate knowledge of background optical properties and time-resolved information in reconstructing images of hemodynamic changes in the neonatal brain from diffuse optical imaging data was studied using Monte Carlo (MC) simulation. A segmented anatomical magnetic resonance (MR) image and literatur...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/54/3/005

    authors: Heiskala J,Hiltunen P,Nissilä I

    更新日期:2009-02-07 00:00:00

  • Quantitative validation of the 3D SAR profile of hyperthermia applicators using the gamma method.

    abstract::For quality assurance of hyperthermia treatment planning systems, quantitative validation of the electromagnetic model of an applicator is essential. The objective of this study was to validate a finite-difference time-domain (FDTD) model implementation of the Lucite cone applicator (LCA) for superficial hyperthermia....

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/52/11/010

    authors: de Bruijne M,Samaras T,Chavannes N,van Rhoon GC

    更新日期:2007-06-07 00:00:00

  • Radiofrequency and microwave dielectric properties of aqueous cryoprotectant agents: dimethyl sulphoxide and 2,3-butanediol.

    abstract::Earlier work on the dielectric properties of cryoprotectant agents is extended using a modified measuring cell and method of data reduction yielding results more efficiently over a temperature range from -75 to +25 degrees C at frequencies from 27 MHz to 3 GHz. Dimethyl sulphoxide and butanediol are investigated at lo...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/43/10/011

    authors: Evans S,bin Azeman A

    更新日期:1998-10-01 00:00:00

  • Potential applications of the quantitative susceptibility mapping (QSM) in MR-guided radiation therapy.

    abstract::Magnetic resonance-guided radiation therapy (MR-GRT) offers great potential to improve radiation treatment outcomes by providing more accurate and patient-tailored therapy. Despite superior soft tissue contrast in MRI, one of the challenges towards MRI-only workflows is that the process often requires some sort of 'MR...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab2623

    authors: Nosrati R,Paudel M,Ravi A,Pejovic-Milic A,Morton G,Stanisz GJ

    更新日期:2019-07-16 00:00:00

  • Evaluating attenuation correction strategies in a dedicated, single-gantry breast PET-tomosynthesis scanner.

    abstract::We are developing a dedicated, combined breast positron emission tomography (PET)-tomosynthesis scanner. Both the PET and digital breast tomosynthesis (DBT) scanners are integrated in a single gantry to provide spatially co-registered 3D PET-tomosynthesis images. The DBT image will be used to identify the breast bound...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/abc5a8

    authors: Krishnamoorthy S,Vent T,Barufaldi B,Maidment ADA,Karp JS,Surti S

    更新日期:2020-10-28 00:00:00