A thermo-sensitive fluorescent agent based method for excitation light leakage rejection for fluorescence molecular tomography.

abstract：:Dose reconstruction is a process that re-creates the treatment-time dose deposited in a patient provided there is knowledge of the delivered energy fluence and the patient's anatomy at the time of treatment. A method for reconstructing dose is presented. The process starts with delivery verification, in which the inci...

journal_title：Physics in medicine and biology

authors： Kapatoes JM,Olivera GH,Balog JP,Keller H,Reckwerdt PJ,Mackie TR

更新日期：2001-04-01 00:00:00

abstract：:The x-ray exposure to patients has become a major concern in computed tomography (CT) and minimizing the radiation exposure has been one of the major efforts in the CT field. Due to plenty high-attenuation tissues in the human chest, under low-dose scan protocols, thoracic low-dose CT (LDCT) images tend to be severely...

journal_title：Physics in medicine and biology

authors： Chen Y,Yang Z,Hu Y,Yang G,Zhu Y,Li Y,Luo L,Chen W,Toumoulin C

更新日期：2012-05-07 00:00:00

abstract：:The amount of silica in the human lung may be estimated by measurement of silicon using in vivo neutron activation analysis. A pulsed, fast neutron beam, produced with a 2 MV Van de Graaff generator using the 2H + 2H reaction, was used to irradiate a Si-doped chest phantom in order to determine minimum detection limit...

journal_title：Physics in medicine and biology

authors： Kacperek A,Ryde SJ,Evans CJ,Dutton J,Morgan WD,Sivyer A

更新日期：1993-06-01 00:00:00

abstract：:The variety of treatment options for cancer patients has increased significantly in recent years. Not only do we combine radiation with surgery and chemotherapy, new therapeutic approaches such as immunotherapy and targeted therapies are starting to play a bigger role. Physics has made significant contributions to rad...

journal_title：Physics in medicine and biology

authors： Grassberger C,Paganetti H

更新日期：2016-11-07 00:00:00

abstract：:In this study, we evaluate the feasibility of designing a beveled fiber-optic probe coupled with a ball lens for improving depth-resolved fluorescence measurements of epithelial tissue using Monte Carlo (MC) simulations. The results show that by using the probe configuration with a beveled tip collection fiber and a f...

journal_title：Physics in medicine and biology

authors： Jaillon F,Zheng W,Huang Z

更新日期：2008-02-21 00:00:00

abstract：:A new mathematical model of the head has been constructed from a set of serial MRI slices from one subject. Finite-difference time-domain (FDTD) calculations of the specific energy absorption rate (SAR) have been performed on this model with a 2 mm resolution for a generic mobile communication transceiver represented ...

journal_title：Physics in medicine and biology

authors： Dimbylow PJ,Mann SM

更新日期：1994-10-01 00:00:00

abstract：:The fluence to organ-dose and effective-dose conversion coefficients for neutrons and protons with energies up to 100 GeV was calculated using the PHITS code coupled to male and female adult reference computational phantoms, which are to be released as a common ICRP/ICRU publication. For the calculation, the radiation...

journal_title：Physics in medicine and biology

authors： Sato T,Endo A,Zankl M,Petoussi-Henss N,Niita K

更新日期：2009-04-07 00:00:00

abstract：:In this paper we describe a method for quantitative photoacoustic tomography (qPAT) based on the photon radiative transfer equation (RTE) coupled with the Helmholtz photoacoustic wave equation. Considerable simulations and tissue-like phantom experiments are conducted to evaluate transport-based qPAT in comparison wit...

journal_title：Physics in medicine and biology

authors： Yao L,Sun Y,Jiang H

更新日期：2010-04-07 00:00:00

abstract：:Digital phantoms continue to play a significant role in modeling and characterizing medical imaging. The currently available XCAT phantom incorporates both the flexibility of mathematical phantoms and the realistic nature of voxelized phantoms. This phantom generates images based on a regular breathing pattern and can...

journal_title：Physics in medicine and biology

authors： Mishra P,St James S,Segars WP,Berbeco RI,Lewis JH

更新日期：2012-06-07 00:00:00

abstract：:In magnetic drug targeting a chemotherapeutic agent is bound to coated magnetic nanoparticles, which are administered to the blood vessel system and subsequently focused by an external applied magnetic field. The optimization of intra-arterial magnetic drug targeting (MDT) requires detailed knowledge about the biodist...

journal_title：Physics in medicine and biology

authors： Richter H,Wiekhorst F,Schwarz K,Lyer S,Tietze R,Alexiou Ch,Trahms L

更新日期：2009-09-21 00:00:00

abstract：:Large volume tissue-equivalent proportional counters are of interest in radiation protection metrology, as the sensitivity in terms of counts per unit absorbed dose in these devices increases as the square of the counter diameter. Conventional solutions to the problem of maintaining a uniform electric field within a c...

journal_title：Physics in medicine and biology

authors： Verma PK,Waker AJ

更新日期：1992-10-01 00:00:00

abstract：:Delivery of pencil beam scanning (PBS) requires the on-line measurement of several beam parameters. If the measurement is outside of specified tolerances and a binary threshold algorithm is used, the beam will be paused. Given instrumentation and statistical noise such a system can lead to many pauses which could incr...

journal_title：Physics in medicine and biology

authors： Clasie BM,Kooy HM,Flanz JB

更新日期：2016-01-07 00:00:00

abstract：:This study was carried out to investigate whether the electronic portal imaging (EPI) acquisition process could be optimized, and as a result tolerance and action levels be set for the PIPSPro QC-3V phantom image quality assessment. The aim of the optimization process was to reduce the dose delivered to the patient wh...

journal_title：Physics in medicine and biology

authors： McGarry CK,Grattan MW,Cosgrove VP

更新日期：2007-12-07 00:00:00

abstract：:EEG recordings made in combined EEG-fMRI studies are corrupted by gradient artefacts (GAs) resulting from the interaction of the EEG system with the time-varying magnetic field gradients used in MRI. The dominant contribution to the GA arises from interaction with the leads of the EEG cap and the human head, but artef...

journal_title：Physics in medicine and biology

authors： Chowdhury ME,Mullinger KJ,Bowtell R

更新日期：2015-06-21 00:00:00

abstract：:Radiotherapy calculations often involve complex geometries such as interfaces between materials of vastly differing atomic number, such as lung, bone and/or air interfaces. Monte Carlo methods have been used to calculate accurately the perturbation effects of the interfaces. However, these methods can be computational...

journal_title：Physics in medicine and biology

authors： Gifford KA,Horton JL,Wareing TA,Failla G,Mourtada F

更新日期：2006-05-07 00:00:00

abstract：:Dual-energy x-ray absorptiometry (DXA) is widely applied for estimating body fat. The percentage of body mass as fat (%fat) is predicted from a DXA-estimated R(ST) value defined as the ratio of soft tissue attenuation at two photon energies (e.g., 40 keV and 70 keV). Theoretically, the R(ST) concept depends on the mas...

journal_title：Physics in medicine and biology

authors： Wang Z,Heymsfield SB,Chen Z,Zhu S,Pierson RN

更新日期：2010-05-07 00:00:00

abstract：:A near-field probe is described that enables high spatial resolution imaging with terahertz (THz) pulses. The spatial resolution capabilities of the system lie in the range of few microns and we demonstrate a resolution of 7 microm using broad-banded THz pulses with an intensity maximum near 0.5 THz. We present a stud...

journal_title：Physics in medicine and biology

authors： Federici JF,Mitrofanov O,Lee M,Hsu JW,Brener I,Harel R,Wynn JD,Pfeiffer LN,West KW

更新日期：2002-11-07 00:00:00

abstract：:Many applications of electroporation, especially those utilizing electrofusion and in-vivo electroporation, involve cell environments that include close cell-to-cell proximity and a wide range of target cell size. It is important to understand how this kind of environment may alter optimum electroporation electrical p...

journal_title：Physics in medicine and biology

authors： Gaynor PT,Bodger PS

更新日期：2006-06-21 00:00:00

abstract：:In modern radiotherapy, it is vitally important to monitor the performance of all linac components including the collimation system. In this study, a simple measurement method and accurate algorithm are introduced for investigation of the secondary and tertiary collimator sag during radiotherapy arc treatments. The me...

journal_title：Physics in medicine and biology

authors： Rowshanfarzad P,Sabet M,O'Connor DJ,Greer PB

更新日期：2012-06-21 00:00:00

abstract：:A bright flash of light is emitted by the plasma formed at the focus of an ophthalmic Nd: YAG laser. The purpose of this investigation is to determine whether the plasma flash constitutes a hazard to the operator. The intensity of the flash at the slit lamp eyepiece was measured and the experimentally derived value wa...

journal_title：Physics in medicine and biology

authors： Moseley H,Allan D

更新日期：1987-09-01 00:00:00

abstract：:Factors influencing the precision of measuring changes in the calcium content of sections of bone, including vertebrae, using reactor neutrons for partial body in vivo activation analysis have been examined and quantified. These factors include (a) the choice of incidient neutron spectrum, (b) the uniformity of activa...

journal_title：Physics in medicine and biology

authors： Boddy K,Glaros D,Robertson I

更新日期：1975-01-01 00:00:00

abstract：:A simple and fast, but sensitive TLD method for the measurement of energy and homogeneity of therapeutically used electron beams has been developed and tested. This method is based on the fact that when small thicknesses of high-Z absorbers such as lead are interposed in the high-energy electron beams, the transmitted...

journal_title：Physics in medicine and biology

authors： Pradhan AS,Quast U,Sharma PK

更新日期：1994-09-01 00:00:00

abstract：:An important challenge in real-world biomedical applications of x-ray phase contrast imaging (XPCI) techniques is the efficient use of the photon flux generated by an incoherent and polychromatic x-ray source. This efficiency can directly influence dose and exposure time and ideally should not affect the superior cont...

journal_title：Physics in medicine and biology

authors： Saghamanesh S,Aghamiri SM,Kamali-Asl A,Yashiro W

更新日期：2017-09-01 00:00:00

abstract：:A method was developed to quantify the intensity of tissue staining using a CCD (charge-coupled device) camera. Reflection spectra of NBT-stained (nitro-blue tetrazolium-stained) and unstained myocardium were recorded via fibre optics coupled to a CCD camera, connected to a microcomputer. The calculation of the intens...

journal_title：Physics in medicine and biology

authors： Schröder T,Koch G,Schnabel PA,Hering JP,Bretschneider HJ,Richter J,Hellige G

更新日期：1991-06-01 00:00:00

abstract：:Arc-therapy is a dose delivery technique regularly applied in photon radiation therapy, and is currently subject of great interest for proton therapy as well. In this technique, proton beams are aimed at a tumor from different continuous ranges of incident directions (so called "arcs"). This technique can potentially ...

journal_title：Physics in medicine and biology

authors： Nesteruk KP,Bolsi A,Lomax AJ,Meer D,van de Water S,Schippers JM

更新日期：2021-01-26 00:00:00

abstract：:Evidence that some lung tumors change shape during respiration is derived from respiratory gated CT data by statistical shape modeling and image manipulation. Some tumors behave as rigid objects while others show systematic shape changes. Two views of lung motion are presented to allow analysis of the results. In the ...

journal_title：Physics in medicine and biology

authors： Kyriakou E,McKenzie DR

更新日期：2012-02-21 00:00:00

abstract：:A phantom study was performed in full-field digital mammography to investigate the opportunity and the magnitude of a possible dose reduction that would leave the image quality above the accepted thresholds associated with some classical phantoms. This preliminary work is intended to lay the groundwork for a future cl...

journal_title：Physics in medicine and biology

authors： Gennaro G,Katz L,Souchay H,Alberelli C,di Maggio C

更新日期：2005-04-21 00:00:00

abstract：:The feasibility of detecting gamma rays with energies below 1.5 MeV by means of a large-volume liquid-filled Cerenkov counter has been examined, together with the characteristics and limitations of an experimental counter. Various liquids (water, glycerol, sodium iodide solution; and glycerol plus a wavelength shifter...

journal_title：Physics in medicine and biology

authors： Hesp R

更新日期：1978-05-01 00:00:00

abstract：:Positron emission tomography (PET) has become an important modality in medical and molecular imaging. However, in most PET applications, the resolution is still mainly limited by the physical crystal sizes or the detector's intrinsic spatial resolution. To achieve images with better spatial resolution in a central reg...

journal_title：Physics in medicine and biology

authors： Li Y,Matej S,Karp JS,Metzler SD

更新日期：2015-01-21 00:00:00

abstract：:Knowledge of what dose-volume histograms can be expected for a previously unseen patient could increase consistency and quality in radiotherapy treatment planning. We propose a machine learning method that uses previous treatment plans to predict such dose-volume histograms. The key to the approach is the framing of d...

journal_title：Physics in medicine and biology

authors： Skarpman Munter J,Sjölund J

更新日期：2015-09-07 00:00:00