Changes in lung tumor shape during respiration.

abstract：:The Monte Carlo method is the most accurate method for radiotherapy dose calculations, if used correctly. However, any Monte Carlo dose calculation is burdened with statistical noise. In this paper, denoising of Monte Carlo dose distributions with a three-dimensional adaptive anisotropic diffusion method was investiga...

journal_title：Physics in medicine and biology

authors： Miao B,Jeraj R,Bao S,Mackie TR

更新日期：2003-09-07 00:00:00

abstract：:Elasticity imaging (EI) is being developed to allow the evaluation of the mechanical properties of soft tissue, but these properties are already assessed in routine ultrasound breast examination using a method that involves the subjective interpretation of tissue motion seen in real-time B-mode image movies during pal...

journal_title：Physics in medicine and biology

authors： Miller NR,Bamber JC

更新日期：2000-08-01 00:00:00

abstract：:In this study, we explore the potential of compressed sensing (CS) accelerated broadband 3D phase-encoded turbo spin-echo (3D-PE-TSE) for the purpose of geometrically undistorted imaging in the presence of field inhomogeneities. To achieve this goal 3D-PE-SE and 3D-PE-TSE sequences with broadband rf pulses and dedicat...

journal_title：Physics in medicine and biology

authors： van Gorp JS,Bakker CJ,Bouwman JG,Smink J,Zijlstra F,Seevinck PR

更新日期：2015-01-21 00:00:00

abstract：:The feasibility is demonstrated of a numerical method to calculate dose deposition by broad high-energy electron beams in homogeneous matter or in heterogeneous matter in which the heterogeneities are arranged in slabs perpendicular to the beam axis. The method is based only on the basic physical interaction processes...

journal_title：Physics in medicine and biology

authors： Huizenga H,Storchi PR

更新日期：1989-10-01 00:00:00

abstract：:Calibration methods are investigated for the determination of bone density by the Compton scattering method. The scattered radiation from materials of different densities and dimensions is measured for this purpose. A function for the dependence of the intensity on these parameters is derived and compared with the exp...

journal_title：Physics in medicine and biology

authors： Leichter I,Weinreb A,Hazan G

更新日期：1980-07-01 00:00:00

abstract：:Image-guided radiation therapy using implanted fiducial markers is a common solution for prostate localization to improve targeting accuracy. However, fiducials that are typically used for conventional photon radiotherapy cause large dose perturbations in patients who receive proton radiotherapy. A proposed solution h...

journal_title：Physics in medicine and biology

authors： Cheung J,Kudchadker RJ,Zhu XR,Lee AK,Newhauser WD

更新日期：2010-12-07 00:00:00

abstract：:Intracoronary thermography is a technique that measures lumen wall temperatures for vulnerable plaque detection. In this paper the influence of vulnerable plaque composition on lumen wall temperatures was studied numerically. Concerning the vulnerable plaque heat generation, the location of the heat source and its hea...

journal_title：Physics in medicine and biology

authors： ten Have AG,Gijsen FJ,Wentzel JJ,Slager CJ,Serruys PW,van der Steen AF

更新日期：2006-11-21 00:00:00

abstract：:Recently, deep learning technology has achieved various successes in medical image analysis studies including computer-aided diagnosis (CADx). However, current CADx approaches based on deep learning have a limitation in interpreting diagnostic decisions. The limited interpretability is a major challenge for practical ...

journal_title：Physics in medicine and biology

authors： Kim ST,Lee JH,Lee H,Ro YM

更新日期：2018-12-04 00:00:00

abstract：:Ultraviolet (UV) treatment dose is determined by the length of time that a patient spends in a phototherapy cabin. The output from UV fluorescent lamps declines with use and a method is needed to compensate for the change in irradiance and to identify and replace any lamps that fail. The decline in lamp output with ag...

journal_title：Physics in medicine and biology

authors： Amatiello H,Martin CJ

更新日期：2006-01-21 00:00:00

abstract：:Radiotherapy treatment planning relies on the use of geometrically correct images. This paper presents a fully automatic tool for correcting MR images for the effects of B(0) inhomogeneities. The post-processing method is based on the gradient-reversal technique of Chang and Fitzpatrick (1992 IEEE Trans. Med. Imaging ...

journal_title：Physics in medicine and biology

authors： Reinsberg SA,Doran SJ,Charles-Edwards EM,Leach MO

更新日期：2005-06-07 00:00:00

abstract：:Deep learning models are highly parameterized, resulting in difficulty in inference and transfer learning for image recognition tasks. In this work, we propose a layered pathway evolution method to compress a deep convolutional neural network (DCNN) for classification of masses in digital breast tomosynthesis (DBT). T...

journal_title：Physics in medicine and biology

authors： Samala RK,Chan HP,Hadjiiski LM,Helvie MA,Richter C,Cha K

更新日期：2018-05-01 00:00:00

abstract：:Dose calculations were performed for a tissue phantom irradiated by uniform circular beams of negative pions with an assumed gaussian momentum distribution. The mean momentum of the pions was varied from 104.4 to 171.5 MeV/c (mean range 5-20 cm in unit-density tissue) and the momentum spread from 0 to 5% of the mean. ...

journal_title：Physics in medicine and biology

authors： Hamm RN,Wright HA,Turner JE

更新日期：1979-05-01 00:00:00

abstract：:Ion chamber dosimetry requires a high degree of precision, at all steps within the dosimetric process, in order to ensure accurate dose measurements. This work presents a novel technique for ion chamber volume determination and quality assurance, using micro-computed tomography (micro-CT). Four nominally identical Exr...

journal_title：Physics in medicine and biology

authors： McNiven AL,Umoh J,Kron T,Holdsworth DW,Battista JJ

更新日期：2008-09-21 00:00:00

abstract：:State of the art point-spread function (PSF) corrections implemented in positron emission tomography/computed tomography (PET/CT) reconstruction improved image quality and diagnostic performance but caused an increase in the standardized uptake value (SUV) compared to a conventional OSEM reconstruction system. The EAN...

journal_title：Physics in medicine and biology

authors： Ferretti A,Chondrogiannis S,Rampin L,Bellan E,Marzola MC,Grassetto G,Gusella S,Maffione AM,Gava M,Rubello D

更新日期：2018-11-26 00:00:00

abstract：:The exponential edge-gradient effect must arise in any x-ray transmission CT scanner whenever long sharp edges of high contrast are encountered. The effect is non-linear and is due to the interaction of the exponential law of x-ray attenuation and the finite width of the scanning beam in the x-y plane. The error induc...

journal_title：Physics in medicine and biology

authors： Joseph PM,Spital RD

更新日期：1981-05-01 00:00:00

abstract：:To achieve accurate and fast deformable image registration (DIR) for pulmonary CT, we proposed a Multi-scale DIR framework with unsupervised Joint training of Convolutional Neural Network (MJ-CNN). MJ-CNN contains three models at multi-scale levels for a coarse-to-fine DIR to avoid being trapped in a local minimum. It...

journal_title：Physics in medicine and biology

authors： Jiang Z,Yin FF,Ge Y,Ren L

更新日期：2020-01-13 00:00:00

abstract：:Exploiting the field response of magnetic tracers, magnetic particle imaging (MPI) allows direct, local quantification of the tracer concentration in bulk structures. Here, we investigated the use of characteristic field response functions to spatially resolve the absolute concentration of multiple nanoparticle specie...

journal_title：Physics in medicine and biology

authors： Han SH,Cho E,Lee DK,Cho G,Kim YR,Cho H

更新日期：2014-11-07 00:00:00

abstract：:Accumulating evidence shows that hyperthermia improves head-and-neck cancer treatment. Over the last decade, we introduced a radiofrequency applicator, named HYPERcollar, which enables local heating also of deep locations in this region. Based on clinical experience, we redesigned the HYPERcollar for improved comfort,...

journal_title：Physics in medicine and biology

authors： Togni P,Rijnen Z,Numan WC,Verhaart RF,Bakker JF,van Rhoon GC,Paulides MM

更新日期：2013-09-07 00:00:00

abstract：:This paper introduces a method to simultaneously minimize the leaf travel distance and the tongue-and-groove effect for IMRT leaf sequences to be delivered in segmental mode. The basic idea is to add a large enough number of openings through cutting or splitting existing openings for those leaf pairs with openings few...

journal_title：Physics in medicine and biology

authors： Dai J,Que W

更新日期：2004-12-07 00:00:00

abstract：:We report a simulation study on diffuse reflective optical computed tomography, in which continuous-wave sources and detectors are placed on the plane surface of a semi-infinite body. We adopted a simple Tikhonov regularization in the inverse problem and demonstrated the feasibility of three-dimensional reconstruction...

journal_title：Physics in medicine and biology

authors： Endoh R,Suzuki A,Fujii M,Nakayama K

更新日期：2004-05-21 00:00:00

abstract：:In order to enable a detailed analysis of radio frequency (RF) absorption in the human middle and inner ear organs, a numerical model of these organs was developed at a spatial resolution of 0.1 mm, based on a real human tissue sample. The dielectric properties of the liquids (perilymph and endolymph) inside the bony ...

journal_title：Physics in medicine and biology

authors： Schmid G,Uberbacher R,Samaras T,Jappel A,Baumgartner WD,Tschabitscher M,Mazal PR

更新日期：2007-04-07 00:00:00

abstract：:Short- and long-term side effects following the treatment of cancer with radiation are strongly related to the amount of dose deposited to the healthy tissue surrounding the tumor. The characterization of the radiation field outside the planned target volume is the first step for estimating health risks, such as devel...

journal_title：Physics in medicine and biology

authors： Tessa CL,Berger T,Kaderka R,Schardt D,Burmeister S,Labrenz J,Reitz G,Durante M

更新日期：2014-04-21 00:00:00

abstract：:The measurement of output factors (OF) for the small photon beams generated by Leksell Gamma Knife® (LGK) radiotherapy units is a challenge for the physicist due to the under or over estimation of these factors by a vast majority of the detectors commercially available. Output correction factors, introduced in the int...

journal_title：Physics in medicine and biology

authors： Benmakhlouf H,Johansson J,Paddick I,Andreo P

更新日期：2015-05-21 00:00:00

abstract：:Ultrasound-based elastography including strain elastography, acoustic radiation force impulse (ARFI) imaging, point shear wave elastography and supersonic shear imaging (SSI) have been used to differentiate breast tumors among other clinical applications. The objective of this study is to extend a previously published...

journal_title：Physics in medicine and biology

authors： Wang Y,Peng B,Jiang J

更新日期：2017-03-07 00:00:00

abstract：:Mean glandular dose (MGD) is the figure of merit to assess breast dose after a mammographic acquisition. The use of normalized MGD obtained from Monte Carlo computations with measured incident air kerma determines the MGD delivered to patients. The Geant4 Application for Tomographic Emission (GATE) toolkit is a modern...

journal_title：Physics in medicine and biology

authors： Myronakis ME,Zvelebil M,Darambara DG

更新日期：2013-04-07 00:00:00

abstract：:Scatter correction is an essential technique to improve the image quality of cone-beam CT (CBCT). Although different scatter correction methods have been proposed in the literature, a standard solution is still being studied due to the limitations including accuracy, computation efficiency and generalization. In this ...

journal_title：Physics in medicine and biology

authors： Jiang Y,Yang C,Yang P,Hu X,Luo C,Xue Y,Xu L,Hu X,Zhang L,Wang J,Sheng K,Niu T

更新日期：2019-07-11 00:00:00

abstract：:Gold nanoparticle (GNP) radio-enhancement is a promising technique to increase the dose deposition in a tumor while sparing neighboring healthy tissue. Previous experimental studies showed effects on cell survival and tumor control for keV x-rays but surprisingly also for MV-photons, proton and carbon-ion beams. In a ...

journal_title：Physics in medicine and biology

authors： Rudek B,McNamara A,Ramos-Méndez J,Byrne H,Kuncic Z,Schuemann J

更新日期：2019-08-28 00:00:00

abstract：:Nanocarriers offer a promising approach to significantly improve therapeutic delivery to solid tumors as well as limit the side effects associated with anti-cancer agents. However, their relatively large size can negatively affect their ability to efficiently penetrate into more interior tumor regions, ultimately redu...

journal_title：Physics in medicine and biology

authors： Mohammadabadi A,Huynh RN,Wadajkar AS,Lapidus RG,Kim AJ,Raub CB,Frenkel V

更新日期：2020-06-22 00:00:00

abstract：:Recent image guidance developments for preclinical synchrotron microbeam radiotherapy represent a necessary step for future clinical translation of the technique. Image quality can be further improved using x-ray phase contrast, which is readily available at synchrotron facilities. We here describe a methodology for p...

journal_title：Physics in medicine and biology

authors： Pelliccia D,Crosbie JC,Larkin KG

更新日期：2016-08-21 00:00:00

abstract：:In this paper we describe a method for quantitative photoacoustic tomography (qPAT) based on the photon radiative transfer equation (RTE) coupled with the Helmholtz photoacoustic wave equation. Considerable simulations and tissue-like phantom experiments are conducted to evaluate transport-based qPAT in comparison wit...

journal_title：Physics in medicine and biology

authors： Yao L,Sun Y,Jiang H

更新日期：2010-04-07 00:00:00