Methodologies in the modeling of combined chemo-radiation treatments.

abstract：:A simple and fast, but sensitive TLD method for the measurement of energy and homogeneity of therapeutically used electron beams has been developed and tested. This method is based on the fact that when small thicknesses of high-Z absorbers such as lead are interposed in the high-energy electron beams, the transmitted...

journal_title：Physics in medicine and biology

authors： Pradhan AS,Quast U,Sharma PK

更新日期：1994-09-01 00:00:00

abstract：:The process of organ motion correction in scintigraphy is analysed in the frequency domain. The sequence of the chi- and gamma- coordinates registered during scintigraphic recording is converted to a frequency spectrum by a discrete Fourier transform. In the frequency domain motion correction is performed by linear fi...

journal_title：Physics in medicine and biology

authors： Schmidlin P

更新日期：1975-05-01 00:00:00

abstract：:Scatter correction is an essential technique to improve the image quality of cone-beam CT (CBCT). Although different scatter correction methods have been proposed in the literature, a standard solution is still being studied due to the limitations including accuracy, computation efficiency and generalization. In this ...

journal_title：Physics in medicine and biology

authors： Jiang Y,Yang C,Yang P,Hu X,Luo C,Xue Y,Xu L,Hu X,Zhang L,Wang J,Sheng K,Niu T

更新日期：2019-07-11 00:00:00

abstract：:Target motion is one of the major limitations of each high precision radiation therapy. Using advanced active beam delivery techniques, such as the magnetic raster scanning system for particle irradiation, the interplay between time-dependent beam and target position heavily distorts the applied dose distribution. Thi...

journal_title：Physics in medicine and biology

authors： Li Q,Groezinger SO,Haberer T,Rietzel E,Kraft G

更新日期：2004-07-21 00:00:00

abstract：:Sparse phased array ultrasound transducers with millimetre length scale elements have previously been proposed for generating hyperthermia but not for imaging. Numerical simulation with a pseudospectral solver was used to investigate: (a) how the position of the maximum pressure in the focal region changed with elemen...

journal_title：Physics in medicine and biology

authors： Wilson AJ

更新日期：2018-07-16 00:00:00

abstract：:In this note, we present the first experimental results of in-beam PET measurements during high energy photon phantom irradiation. An inhomogeneous phantom was irradiated with pulsed 34 MV bremsstrahlung. The measurements have been conducted with a dedicated double head positron camera. A high material contrast could ...

journal_title：Physics in medicine and biology

authors： Kluge T,Möckel D,Pawelke J,Enghardt W

更新日期：2007-10-21 00:00:00

abstract：:This paper introduces a method to simultaneously minimize the leaf travel distance and the tongue-and-groove effect for IMRT leaf sequences to be delivered in segmental mode. The basic idea is to add a large enough number of openings through cutting or splitting existing openings for those leaf pairs with openings few...

journal_title：Physics in medicine and biology

authors： Dai J,Que W

更新日期：2004-12-07 00:00:00

abstract：:Elevated interstitial fluid pressure is one of the barriers of drug delivery in solid tumors. Recent studies have shown that normalization of tumor vasculature by anti-angiogenic factors may improve the delivery of conventional cytotoxic drugs, possibly by increasing blood flow, decreasing interstitial fluid pressure,...

journal_title：Physics in medicine and biology

authors： Ozturk D,Yonucu S,Yilmaz D,Unlu MB

更新日期：2015-02-21 00:00:00

abstract：:Both inhomogeneity in the main magnetic field and non-linearity in the gradient fields introduce errors in NMR images reconstructed from projections. It is found that the image artefacts caused by these two sources are separable. The inhomogeneous main field blurs the image while the nonlinear gradients distort the im...

journal_title：Physics in medicine and biology

authors： Lai CM

更新日期：1983-08-01 00:00:00

abstract：:In interstitial heating one of the main requirements for achieving a certain elevated temperature in a tumour is that the effective power per applicator (Peff), i.e. the power which is actually deposited in the tissue, is sufficiently high. In this paper this requirement is discussed for the applicators of the 27 MHz ...

journal_title：Physics in medicine and biology

authors： Kaatee RS,Crezee J,Kanis AP,Lagendijk JJ,Levendag PC,Visser AG

更新日期：1997-06-01 00:00:00

abstract：:Carotid atherosclerosis measurements for eight subjects at baseline and 14 +/- 2 days later were examined using 1.5 T and 3.0 T magnetic resonance imaging (MRI). A single observer blinded to field strength, subject and timepoint manually segmented carotid artery wall and lumen boundaries in randomized images in five m...

journal_title：Physics in medicine and biology

authors： Vidal A,Bureau Y,Wade T,Spence JD,Rutt BK,Fenster A,Parraga G

更新日期：2008-12-07 00:00:00

abstract：:A method is presented to predict beam profiles and outputs for wedged asymmetric fields defined by independent collimator jaws allowing fast generation of beam profiles whilst requiring very little additional data to that already used by most treatment planning systems in generating symmetric field isodoses. Symmetric...

journal_title：Physics in medicine and biology

authors： Millin AE,Smith CW

更新日期：1994-01-01 00:00:00

abstract：:Radiation therapy is an image-guided process whose success critically depends on the imaging modality used for treatment planning and the level of integration of the available imaging information. In this work, we establish a dose optimization framework for incorporating metabolic information from functional imaging m...

journal_title：Physics in medicine and biology

authors： Xing L,Cotrutz C,Hunjan S,Boyer AL,Adalsteinsson E,Spielman D

更新日期：2002-10-21 00:00:00

abstract：:Grating interferometry is advantageous over conventional x-ray absorption imaging because it enables the detection of samples constituted by low atomic number elements (low-Z materials). Therefore, it has a potential application in biological science and medical diagnostics. The grating interferometry has some critica...

journal_title：Physics in medicine and biology

authors： Du Y,Lei Y,Liu X,Huang J,Zhao Z,Guo J,Li J,Niu H

更新日期：2016-12-07 00:00:00

abstract：:Diffusion weighted magnetic resonance imaging offers a non-invasive tool to explore the three-dimensional structure of brain white matter in clinical practice. Anisotropic diffusion hardware phantoms are useful for the quantitative validation of this technique. This study provides guidelines on how to manufacture anis...

journal_title：Physics in medicine and biology

authors： Fieremans E,De Deene Y,Delputte S,Ozdemir MS,Achten E,Lemahieu I

更新日期：2008-10-07 00:00:00

abstract：:Average cross-sections for inactivation of dry ribonuclease by H, He and N projectiles with energies between 100 eV and 10 keV are presented. The trend of the damage cross-sections with particle energy is consistent with the trend of the molecular quasi-elastic scattering and ionization cross-sections. A tentative rad...

journal_title：Physics in medicine and biology

authors： Watt DE,Sutcliffe JF

更新日期：1975-11-01 00:00:00

abstract：:In this paper we describe a method for quantitative photoacoustic tomography (qPAT) based on the photon radiative transfer equation (RTE) coupled with the Helmholtz photoacoustic wave equation. Considerable simulations and tissue-like phantom experiments are conducted to evaluate transport-based qPAT in comparison wit...

journal_title：Physics in medicine and biology

authors： Yao L,Sun Y,Jiang H

更新日期：2010-04-07 00:00:00

abstract：:Treatment planning based on probability distribution function (PDF) of patient geometries has been shown a potential off-line strategy to incorporate organ motion, but the application of such approach highly depends upon the reproducibility of the PDF. In this paper, we investigated the dependences of the PDF reproduc...

journal_title：Physics in medicine and biology

authors： Cai J,Read PW,Altes TA,Molloy JA,Brookeman JR,Sheng K

更新日期：2007-01-21 00:00:00

abstract：:Discrete implanted liver tumours in the rat have been exposed to arrays of 1.7 MHz ultrasound lesions. Focal peak intensities in the range 1.4-3.5 k Wcm-2 were used for an exposure time of 10 s. It has been demonstrated that where the whole tumour volume was exposed to the focused ultrasound beam, no evidence of tumou...

journal_title：Physics in medicine and biology

authors： ter Haar G,Rivens I,Chen L,Riddler S

更新日期：1991-11-01 00:00:00

abstract：:The intra- and inter-batch accuracy and precision of MRI (polyacrylamide gelatin gel fabricated at atmospheric conditions) polymer gel dosimeters are assessed in full 3D. In the intra-batch study, eight spherical flasks were filled with the same polymer gel along with a set of test tubes that served as calibration pha...

journal_title：Physics in medicine and biology

authors： Vandecasteele J,De Deene Y

更新日期：2013-01-07 00:00:00

abstract：:In modern radiotherapy, it is vitally important to monitor the performance of all linac components including the collimation system. In this study, a simple measurement method and accurate algorithm are introduced for investigation of the secondary and tertiary collimator sag during radiotherapy arc treatments. The me...

journal_title：Physics in medicine and biology

authors： Rowshanfarzad P,Sabet M,O'Connor DJ,Greer PB

更新日期：2012-06-21 00:00:00

abstract：:Megavoltage (MV) cone-beam computed tomography (CBCT) using an electronic portal imaging (EPID) offers advantageous features, including 3D mapping, treatment beam registration, high-z artifact suppression, and direct radiation dose calculation. Adoption has been slowed by image quality limitations and concerns about i...

journal_title：Physics in medicine and biology

authors： Hu YH,Fueglistaller R,Myronakis M,Rottmann J,Wang A,Shedlock D,Morf D,Baturin P,Huber P,Star-Lack J,Berbeco R

更新日期：2018-06-20 00:00:00

abstract：:A 4D ordered-subsets maximum a posteriori (OSMAP) algorithm for dynamic SPECT is described which uses a temporal prior that constrains each voxel's behaviour in time to conform to a compartmental model. No a priori limitations on kinetic parameters are applied; rather, the parameter estimates evolve as the algorithm i...

journal_title：Physics in medicine and biology

authors： Kadrmas DJ,Gullberg GT

更新日期：2001-05-01 00:00:00

abstract：:The aim of this study was to systematically investigate the influence of the inter- and intra-observer segmentation variation of tumors and organs at risk on the simulated temperature coverage of the target. CT scans of six patients with tumors in the pelvic region acquired for radiotherapy treatment planning were use...

journal_title：Physics in medicine and biology

authors： Aklan B,Hartmann J,Zink D,Siavooshhaghighi H,Merten R,Putz F,Ott O,Fietkau R,Bert C

更新日期：2017-05-08 00:00:00

abstract：:The artificial urinary sphincter should be long enough to prevent strangulation effects of the urethral tissue and short enough to avoid the improper dissection of the surrounding tissue. To optimize the sphincter length, the empirical three-parameter urethra compression model is proposed based on the mechanical prope...

journal_title：Physics in medicine and biology

authors： Marti F,Leippold T,John H,Blunschi N,Müller B

更新日期：2006-03-07 00:00:00

abstract：:Proton therapy potentially offers excellent dose conformality and reduction in integral dose. The superior dose distribution is, however, much more sensitive to the radiological depth along the beam path than for photon fields. Variations in this depth due to inaccurate planning calculation, setup uncertainty, respira...

journal_title：Physics in medicine and biology

authors： Lu HM

更新日期：2008-03-07 00:00:00

abstract：:The external radiation exposure from an overhead plume containing gamma emitting radionuclides can contribute substantial dose to the ground receptor during normal operations as well as accidental release conditions of nuclear facilities. In order to estimate the effective dose conversion coefficients (DCCs) directly,...

journal_title：Physics in medicine and biology

authors： Dey R,Patni HK,Deo Singh K,Kulkarni MS,Anand S

更新日期：2019-08-01 00:00:00

abstract：:Ultra-wideband (UWB) electromagnetic pulses of nanosecond duration, or nanopulses, have recently been approved by the Federal Communications Commission for a number of different applications. They are also being explored for applications in biotechnology and medicine. The simulation of the propagation of a nanopulse t...

journal_title：Physics in medicine and biology

authors： Simicevic N

更新日期：2005-11-07 00:00:00

abstract：:In positron emission tomography (PET), there is an increasing interest in studying not only the regional mean tracer concentration, but its variation arising from local differences in physiology, the tissue heterogeneity. However, in reconstructed images this physiological variation is shadowed by a large reconstructi...

journal_title：Physics in medicine and biology

authors： Forma J,Niemi JA,Ruotsalainen U

更新日期：2013-07-21 00:00:00

abstract：:The objective of this study was the determination of the thermal regulatory and the thermal breakdown thresholds for in-tube restrained B6C3F1 and NMRI mice exposed to radiofrequency electromagnetic fields at 905 MHz. Different levels of the whole-body averaged specific absorption rate (SAR = 0, 2, 5, 7.2, 10, 12.6 an...

journal_title：Physics in medicine and biology

authors： Ebert S,Eom SJ,Schuderer J,Apostel U,Tillmann T,Dasenbrock C,Kuster N

更新日期：2005-11-07 00:00:00