A potential method for in vivo range verification in proton therapy treatment.

abstract：:In this paper, we have investigated the feasibility of imaging the mechanical behavior of poroelastic materials using axial strain elastography. Cylindrical samples obtained from poroelastic materials having different elastic and permeability properties were subjected to a constant compression force (a classical creep...

journal_title：Physics in medicine and biology

authors： Righetti R,Righetti M,Ophir J,Krouskop TA

更新日期：2007-06-07 00:00:00

abstract：:Most tissue characterization methods use RF data originating from backscattering processes in the insonified tissue. Characterization of the tissue of a thin layer (e.g., an artery wall) poses problems because of the small amount of data available. The tissue layer may be so thin that there are no RF data that are not...

journal_title：Physics in medicine and biology

authors： Linssen FM,Hoeks AP,Brands PJ

更新日期：1991-10-01 00:00:00

abstract：:A general theory is presented for minimizing noise in linear dimension reduction of sequences of medical images when the factors and the covariance matrix and mean of the noise are given. A dimension reduction is optimal when all diagonal elements in the covariance matrix of the noise in the signal (factor) space are ...

journal_title：Physics in medicine and biology

authors： Hermansen F,Lammertsma AA

更新日期：1995-11-01 00:00:00

abstract：:The free space method using a pair of lens antennas was modified for the complex permittivity measurement of biological samples from 20 to 110 GHz. Two methodologies were used to obtain the complex permittivities by the free space method, which were based on the reflection and transmission coefficients. The measuremen...

journal_title：Physics in medicine and biology

authors： Sasaki K,Segawa H,Mizuno M,Wake K,Watanabe S,Hashimoto O

更新日期：2013-03-07 00:00:00

abstract：:A micro-multileaf collimator (microMLC) for stereotactic radiosurgery is used for determination of the spatial intensity distribution of the photon source of a linear accelerator. The method is based on grid field dose measurements using film dosimetry and is easy to perform. Since the microMLC does not allow 'direct'...

journal_title：Physics in medicine and biology

authors： Treuer H,Hoevels M,Luyken K,Hunsche S,Kocher M,Müller RP,Sturm V

更新日期：2003-08-07 00:00:00

abstract：:The artificial urinary sphincter should be long enough to prevent strangulation effects of the urethral tissue and short enough to avoid the improper dissection of the surrounding tissue. To optimize the sphincter length, the empirical three-parameter urethra compression model is proposed based on the mechanical prope...

journal_title：Physics in medicine and biology

authors： Marti F,Leippold T,John H,Blunschi N,Müller B

更新日期：2006-03-07 00:00:00

abstract：:Tserng and Kalhan have raised the question of the appropriate equation to use for the measurement of turnover rate in a stable-isotope study. In a comparison of glucose turnover measured with 2H-glucose and with 13C-glucose they used five apparently different equations and obtained conflicting answers. There is, howev...

journal_title：Physics in medicine and biology

authors： Wootton R,Ford GC,Cheng KN,Halliday D

更新日期：1985-10-01 00:00:00

abstract：:The presence of motion artifacts is a typical problem in thoracic imaging. However, synchronizing the respiratory cycle with computed tomography (CT) image acquisition can reduce these artifacts. We currently employ a method of in vivo respiratory-gated micro-CT imaging for small laboratory animals (mice). This proced...

journal_title：Physics in medicine and biology

authors： Walters EB,Panda K,Bankson JA,Brown E,Cody DD

更新日期：2004-09-07 00:00:00

abstract：:An inflatable endorectal balloon (ERB) is often used during stereotactic body radiation therapy (SBRT) for treatment of prostate cancer in order to reduce both intrafraction motion of the target and risk of rectal toxicity. However, the ERB can exert significant force on the prostate, and this work assessed the impact...

journal_title：Physics in medicine and biology

authors： Jones BL,Gan G,Kavanagh B,Miften M

更新日期：2013-11-21 00:00:00

abstract：:Automatic cell cycle analysis (DNA histograms) is usually performed with flow cytometry. In cases when only few cells are available, the DNA content has to be measured with a fluorescence microscope combined with sensitive camera systems (SIT, MCP, cooled CCDs) and a frame grabber for image analysis. The fluorescent c...

journal_title：Physics in medicine and biology

authors： Böcker W,Gantenberg HW,Müller WU,Streffer C

更新日期：1996-03-01 00:00:00

abstract：:An in vivo method for the determination of Cd levels in human kidney and liver has been developed. The method allows detection of absolute quantities of Cd in the left kidney and Cd concentration in the liver. The limit of detection of cadmium is 2.5 mg for the left kidney and 1.8 microgram/g (wet weight) for the live...

journal_title：Physics in medicine and biology

authors： Vartsky D,Ellis KJ,Chen NS,Cohn SH

更新日期：1977-11-01 00:00:00

abstract：:The aim of this study is to investigate the use of mathematical morphology for the determination of left ventricular contours in scintigraphic images using multigated radionuclide angiography. We have developed a completely automatic method that first restores the image with a Wiener filter, then finds the region wher...

journal_title：Physics in medicine and biology

authors： Pladellorens J,Serrat J,Castell A,Yzuel MJ

更新日期：1993-12-01 00:00:00

abstract：:Radionuclides which decay by electron capture accompanied by Auger electron cascades, or by beta emission are thought to be excessively damaging when incorporated into the molecular structure of mammalian cell nuclei and thereby pose a radiation hazard which is not assessable by conventional dosimetry. Survival data, ...

journal_title：Physics in medicine and biology

authors： Younis AR,Watt DE

更新日期：1989-07-01 00:00:00

abstract：:Managing uncertainty is a major challenge in radiation therapy treatment planning, including uncertainty induced by intrafraction motion, which is particularly important for tumours in the thorax and abdomen. Common methods to account for motion are to introduce a margin or to convolve the static dose distribution wit...

journal_title：Physics in medicine and biology

authors： Chan TC,Bortfeld T,Tsitsiklis JN

更新日期：2006-05-21 00:00:00

abstract：:In order to measure in vivo resistivity of tissues in the thorax, the possibility of combining anatomical data extracted from high-resolution images with multiple-electrode impedance measurements, a priori knowledge of the range of tissue resistivities, and a priori data on the instrumentation noise is assessed in thi...

journal_title：Physics in medicine and biology

authors： Eyüboğlu BM,Pilkington TC,Wolf PD

更新日期：1994-01-01 00:00:00

abstract：:Sparse-view CT reconstruction algorithms via total variation (TV) optimize the data iteratively on the basis of a noise- and artifact-reducing model, resulting in significant radiation dose reduction while maintaining image quality. However, the piecewise constant assumption of TV minimization often leads to the appea...

journal_title：Physics in medicine and biology

authors： Niu S,Gao Y,Bian Z,Huang J,Chen W,Yu G,Liang Z,Ma J

更新日期：2014-06-21 00:00:00

abstract：:We investigated the physical characteristics of two complementary metal oxide semiconductor (CMOS) mammography detectors. The detectors featured 14-bit image acquisition, 50 microm detector element (del) size and an active area of 5 cm x 5 cm. One detector was a passive-pixel sensor (PPS) with signal amplification per...

journal_title：Physics in medicine and biology

authors： Elbakri IA,McIntosh BJ,Rickey DW

更新日期：2009-03-21 00:00:00

abstract：:Treatment planning for proton tumor therapy requires a fast and accurate dose-calculation method. We have implemented a simplified Monte Carlo (SMC) method in the treatment planning system of the National Cancer Center Hospital East for the double-scattering beam delivery scheme. The SMC method takes into account the ...

journal_title：Physics in medicine and biology

authors： Hotta K,Kohno R,Takada Y,Hara Y,Tansho R,Himukai T,Kameoka S,Matsuura T,Nishio T,Ogino T

更新日期：2010-06-21 00:00:00

abstract：:The use of calibrated tissue-equivalent (TE) ionisation chambers is commonly considered to be the most practical method for total absorbed dose determinations in mixed neutron-photon fields for biomedical applications. The total absorbed dose can be derived from the charge produced within the cavity of an ionisation c...

journal_title：Physics in medicine and biology

authors： Zoetelief J,Broerse JJ

更新日期：1983-05-01 00:00:00

abstract：:Despite the early recognition of the potential of proton imaging to assist proton therapy (Cormack 1963 J. Appl. Phys. 34 2722), the modality is still removed from clinical practice, with various approaches in development. For proton-counting radiography applications such as computed tomography (CT), the water-equival...

journal_title：Physics in medicine and biology

authors： Poludniowski G,Allinson NM,Anaxagoras T,Esposito M,Green S,Manolopoulos S,Nieto-Camero J,Parker DJ,Price T,Evans PM

更新日期：2014-06-07 00:00:00

abstract：:To replace the conventional pinhole (normal cone-beam) collimator, a novel skew-slit collimator was previously proposed and a Novikov-type algorithm developed to reconstruct images using the skew-slit geometry. The goal of this paper is to develop a reconstruction algorithm that has better noise control than the Novik...

journal_title：Physics in medicine and biology

authors： Tang Q,Zeng GL,Huang Q

更新日期：2006-12-07 00:00:00

abstract：:Intra-fractional motion is a concern during prostate radiation therapy, as it may cause deviations between planned and delivered radiation doses. Because accurate motion information during treatment delivery is critical to address dose deviation, we developed the projection marker matching method (PM3), a novel method...

journal_title：Physics in medicine and biology

authors： Chi Y,Rezaeian NH,Shen C,Zhou Y,Lu W,Yang M,Hannan R,Jia X

更新日期：2017-07-07 00:00:00

abstract：:Micro-CT is widely used in preclinical studies, generating substantial interest in extending its capabilities in functional imaging applications such as blood perfusion and cardiac function. However, imaging cardiac structure and function in mice is challenging due to their small size and rapid heart rate. To overcome...

journal_title：Physics in medicine and biology

authors： Holbrook M,Clark DP,Badea CT

更新日期：2018-01-09 00:00:00

abstract：:A solid dynamic phantom with tissue-like optical properties is presented, which contains seven discrete targets impregnated with thermochromic pigment located at different depths from the surface. Changes in absorption are obtained in response to localized heating of the targets, simulating haemodynamic changes occurr...

journal_title：Physics in medicine and biology

authors： Correia T,Banga A,Everdell NL,Gibson AP,Hebden JC

更新日期：2009-10-21 00:00:00

abstract：:Electron depth-dose curves and spectra have been measured from an experimental accelerator on which both energy and spectral shape could be varied independently. The measurements were made at nominal energies of 6 and 12 MeV, with the energy spread (FWHM) varied from 1.7% to over 10% of average energy. Changes in dept...

journal_title：Physics in medicine and biology

authors： Johnsen SW,LaRiviere PD,Tanabe E

更新日期：1983-12-01 00:00:00

abstract：:A theoretical analysis is presented of the biologically effective dose of the solar long wave ultraviolet radiation (UVA) received by patients who are being treated for psoriasis by oral psoralen photochemotherapy. It is shown that patients treated during the summer months in the UK may well receive a UV dose which is...

journal_title：Physics in medicine and biology

authors： Diffey BL

更新日期：1981-11-01 00:00:00

abstract：:The effects of radiation damage, tumour repopulation and cell sublethal damage repair and the possibility of extracting information about the model parameters describing them are investigated in this work. Previously published data on two different cultured cell lines were analysed with the help of a tumour control pr...

journal_title：Physics in medicine and biology

authors： Stavrev P,Weldon M,Warkentin B,Stavreva N,Fallone BG

更新日期：2005-07-07 00:00:00

abstract：:The 'EXACT3D' positron tomograph, which is now in routine clinical research use, was developed with the aim of achieving unprecedented sensitivity, high spatial and temporal resolution and simplicity of design using proven detector technology. It consists of six rings of standard detector blocks (CTI/Siemens EXACT HR+...

journal_title：Physics in medicine and biology

authors： Spinks TJ,Jones T,Bloomfield PM,Bailey DL,Miller M,Hogg D,Jones WF,Vaigneur K,Reed J,Young J,Newport D,Moyers C,Casey ME,Nutt R

更新日期：2000-09-01 00:00:00

abstract：:Detectors used for positron emission tomography (PET) provide fast, randomly distributed signals that need to be digitized for further processing. One possibility is to sample the signals at the peak initiated by a trigger from a constant fraction discriminator (CFD). For PET detectors, simultaneous acquisition of man...

journal_title：Physics in medicine and biology

authors： Judenhofer MS,Pichler BJ,Cherry SR

更新日期：2005-01-07 00:00:00

abstract：:Dual energy computed tomography (DECT) is currently a subject of extensive investigation. DECT is currently implemented using either a dual source scanner with high and low kVp data acquired from separate sources or a single source scanner with both high and low kVp data acquired in an alternating manner. Both methods...

journal_title：Physics in medicine and biology

authors： Szczykutowicz TP,Chen GH

更新日期：2010-11-07 00:00:00