Electron depth-dose dependence on energy spectral quality.

abstract：:Treatment plans optimized for intensity modulated proton therapy (IMPT) may be sensitive to range variations. The dose distribution may deteriorate substantially when the actual range of a pencil beam does not match the assumed range. We present two treatment planning concepts for IMPT which incorporate range uncertai...

journal_title：Physics in medicine and biology

authors： Unkelbach J,Chan TC,Bortfeld T

更新日期：2007-05-21 00:00:00

abstract：:The UMC Utrecht is constructing a 1.5 T MRI scanner integrated with a linear accelerator (Lagendijk et al 2008 Radiother. Oncol. 86 25-9). The goal of this device is to facilitate soft-tissue contrast based image-guided radiotherapy, in order to escalate the dose to the tumour while sparing surrounding normal tissues....

journal_title：Physics in medicine and biology

authors： Meijsing I,Raaymakers BW,Raaijmakers AJ,Kok JG,Hogeweg L,Liu B,Lagendijk JJ

更新日期：2009-05-21 00:00:00

abstract：:The purpose of this study is to investigate whether quality assurance (QA) for cone-beam computed tomography (CBCT) image rotation is necessary in order to ensure the accuracy of CBCT based image-guided radiation therapy (IGRT) and adaptive radiotherapy (ART). Misregistration of angular coordinates during CBCT acquisi...

journal_title：Physics in medicine and biology

authors： Ayan AS,Lin H,Yeager C,Deville C,McDonough J,Zhu TC,Anderson N,Bar Ad V,Lu HM,Both S

更新日期：2013-02-21 00:00:00

abstract：:This study evaluates the performance of the Bruker positron emission tomograph (PET) insert combined with a BioSpec 70/30 USR magnetic resonance imaging (MRI) scanner using the manufacturer acceptance protocol and the NEMA NU 4-2008 for small animal PET. The PET insert is made of 3 rings of 8 monolithic LYSO crystals ...

journal_title：Physics in medicine and biology

authors： Gsell W,Molinos C,Correcher C,Belderbos S,Wouters J,Junge S,Heidenreich M,Vande Velde G,Rezaei A,Nuyts J,Cawthorne C,Cleeren F,Nannan L,Deroose CM,Himmelreich U,González Martínez AJ

更新日期：2020-06-26 00:00:00

abstract：:A system is described in which large superficial areas of tissue may be heated using a single plane ultrasonic transducer scanned in a raster fashion. The shape of the heated area is determined by the movement of a microswitch which is activated when it strikes the rigid edge of a hole of the required shape cut in a p...

journal_title：Physics in medicine and biology

authors： ter Haar G,Hopewell JW

更新日期：1985-12-01 00:00:00

abstract：:EEG recordings made in combined EEG-fMRI studies are corrupted by gradient artefacts (GAs) resulting from the interaction of the EEG system with the time-varying magnetic field gradients used in MRI. The dominant contribution to the GA arises from interaction with the leads of the EEG cap and the human head, but artef...

journal_title：Physics in medicine and biology

authors： Chowdhury ME,Mullinger KJ,Bowtell R

更新日期：2015-06-21 00:00:00

abstract：:ICRP Publication 116 on 'Conversion coefficients for radiological protection quantities for external radiation exposures', provides fluence-to-dose conversion coefficients for organ-absorbed doses and effective dose for various types of external exposures (ICRP 2010 ICRP Publication 116). The publication supersedes th...

journal_title：Physics in medicine and biology

authors： Petoussi-Henss N,Bolch WE,Eckerman KF,Endo A,Hertel N,Hunt J,Menzel HG,Pelliccioni M,Schlattl H,Zankl M

更新日期：2014-09-21 00:00:00

abstract：:The quality of thorax and pelvis transmission scans and therefore of attenuation correction in PET depends on patient thickness and transmission rod source strength. The purpose of the present study was to assess the feasibility of using count-based transmission scans, thereby guaranteeing more consistent image qualit...

journal_title：Physics in medicine and biology

authors： Boellaard R,van Lingen A,van Balen SC,Lammertsma AA

更新日期：2004-02-21 00:00:00

abstract：:The values of the replacement correction factors (P(repl), or in the IAEA's notation p(dis)p(cav)) used for cylindrical chambers in high-energy photon beams represent one of the most significant differences between the AAPM and the IAEA dosimetry protocols. In a previous study (Wang L L W and Rogers D W O 2008 Med. Ph...

journal_title：Physics in medicine and biology

authors： Wang LL,Rogers DW

更新日期：2009-03-21 00:00:00

abstract：:The aim of the present work was to implement the kinetics of cisplatin into a previously developed tumour growth model and to simulate the combined cisplatin-radiotherapy treatment with the emphasis on time sequencing and scheduling of drug and radiation. An investigation into whether the effect of cisplatin-radiation...

journal_title：Physics in medicine and biology

authors： Marcu L,Bezak E,Olver I

更新日期：2006-08-07 00:00:00

abstract：:A detailed Monte Carlo model of a proton therapy treatment head was commissioned to simulate the delivery of small field proton treatments. Small fields are challenging in the planning and quality assurance process because of aperture scattering and dosimetric disequilibrium. Four patients with small fields used in al...

journal_title：Physics in medicine and biology

authors： Bednarz B,Daartz J,Paganetti H

更新日期：2010-12-21 00:00:00

abstract：:Segmentation is often required for the analysis of dynamic positron emission tomography (PET) images. However, noise and low spatial resolution make it a difficult task and several supervised and unsupervised methods have been proposed in the literature to perform the segmentation based on semi-automatic clustering of...

journal_title：Physics in medicine and biology

authors： Mouysset S,Zbib H,Stute S,Girault JM,Charara J,Noailles J,Chalon S,Buvat I,Tauber C

更新日期：2013-10-07 00:00:00

abstract：:To monitor and strategically control energy deposition in magnetic resonance imaging (MRI), measured as a specific absorption rate (SAR), numerical methods using generic human models have been employed to estimate worst-case values. Radiofrequency (RF) sequences are therefore often designed conservatively with large s...

journal_title：Physics in medicine and biology

authors： Jin J,Liu F,Weber E,Crozier S

更新日期：2012-12-21 00:00:00

abstract：:It is a challenging problem to resolve and identify drug (or non-specific fluorophore) distribution throughout the whole body of small animals in vivo. In this article, an algorithm of unmixing multispectral fluorescence tomography (MFT) images based on independent component analysis (ICA) is proposed to solve this pr...

journal_title：Physics in medicine and biology

authors： Pu H,Zhang G,He W,Liu F,Guang H,Zhang Y,Bai J,Luo J

更新日期：2014-09-07 00:00:00

abstract：:Earlier work on the dielectric properties of cryoprotectant agents is extended using a modified measuring cell and method of data reduction yielding results more efficiently over a temperature range from -75 to +25 degrees C at frequencies from 27 MHz to 3 GHz. Dimethyl sulphoxide and butanediol are investigated at lo...

journal_title：Physics in medicine and biology

authors： Evans S,bin Azeman A

更新日期：1998-10-01 00:00:00

abstract：:Contemporary imaging modalities can now provide the surgeon with high quality three- and four-dimensional images depicting not only normal anatomy and pathology, but also vascularity and function. A key component of image-guided surgery (IGS) is the ability to register multi-modal pre-operative images to each other an...

journal_title：Physics in medicine and biology

authors： Peters TM

更新日期：2006-07-21 00:00:00

abstract：:There are three ways to determine the spectrum of a clinical photon beam: direct measurement, modelling the source and reconstruction from ion-chamber measurements. We focus on reconstruction because the necessary equipment is readily available and it provides independent confirmation of source models for a given mach...

journal_title：Physics in medicine and biology

authors： Armbruster B,Hamilton RJ,Kuehl AK

更新日期：2004-11-21 00:00:00

abstract：:In magnetic drug targeting a chemotherapeutic agent is bound to coated magnetic nanoparticles, which are administered to the blood vessel system and subsequently focused by an external applied magnetic field. The optimization of intra-arterial magnetic drug targeting (MDT) requires detailed knowledge about the biodist...

journal_title：Physics in medicine and biology

authors： Richter H,Wiekhorst F,Schwarz K,Lyer S,Tietze R,Alexiou Ch,Trahms L

更新日期：2009-09-21 00:00:00

abstract：:The aim of this study was to develop a model exploiting artificial neural networks (ANNs) to correlate dosimetric and clinical variables with late rectal bleeding in prostate cancer patients undergoing radical radiotherapy and to compare the ANN results with those of a standard logistic regression (LR) analysis. 718 m...

journal_title：Physics in medicine and biology

authors： Tomatis S,Rancati T,Fiorino C,Vavassori V,Fellin G,Cagna E,Mauro FA,Girelli G,Monti A,Baccolini M,Naldi G,Bianchi C,Menegotti L,Pasquino M,Stasi M,Valdagni R

更新日期：2012-03-07 00:00:00

abstract：:We investigate an optimization-based reconstruction, with an emphasis on image-artifact reduction, from data collected in C-arm cone-beam computed tomography (CBCT) employed in image-guided interventional procedures. In the study, an image to be reconstructed is formulated as a solution to a convex optimization progra...

journal_title：Physics in medicine and biology

authors： Xia D,Langan DA,Solomon SB,Zhang Z,Chen B,Lai H,Sidky EY,Pan X

更新日期：2016-10-21 00:00:00

abstract：:Magnetic resonance imaging (MRI) may be used to image three-dimensional dose distributions of ionizing radiation in tissue equivalent gels infused with ferrous sulphate solutions, commonly known as Fricke gels. In this technique, ferrous (Fe2+) ions are oxidized to ferric (Fe3+) ions by free radicals produced by ioniz...

journal_title：Physics in medicine and biology

authors： Harris PJ,Piercy A,Baldock C

更新日期：1996-09-01 00:00:00

abstract：:Protons and carbon ion beams for hadron therapy can be delivered by cyclotrons with a fixed energy. In order to treat patients, an energy degrader along the beam line will be used to match the particle range with the target depth. Fragmentation reactions of carbon ions inside the degrader material could introduce a sm...

journal_title：Physics in medicine and biology

authors： Morone MC,Calabretta L,Cuttone G,Fiorini F

更新日期：2008-11-07 00:00:00

abstract：:The Hug-Kellerer (H-K) equation is one of the earliest proposed radiation cell survival curves. We examine this equation in view of the recent perceived need for a universal cell survival curve which would be applicable to single radiation fractions at high doses. We derive relationships between the three parameters o...

journal_title：Physics in medicine and biology

authors： Ekstrand KE

更新日期：2010-05-21 00:00:00

abstract：:New definitions of the absorbed dose conversion factors Clambda and CE are proposed. The absorbed dose in water is given by the product of absorbed dose conversion factor, exposure calibration factor, ionisation chamber reading, cap displacement correction factor and perturbation correction factor. At exposure calibra...

journal_title：Physics in medicine and biology

authors： Shiragai A

更新日期：1978-03-01 00:00:00

abstract：:Usually, Monte Carlo models are validated against experimental data. However, models of multiple Coulomb scattering (MCS) in the Gaussian approximation are exceptional in that we have theories which are probably more accurate than the experiments which have, so far, been done to test them. In problems directly sensiti...

journal_title：Physics in medicine and biology

authors： Makarova A,Gottschalk B,Sauerwein W

更新日期：2017-07-06 00:00:00

abstract：:A number of radiation-therapy-related uses based on a commercially available spreadsheet program have been developed at our facility. The graphics and display capabilities inherent in these spreadsheet programs allow for concise visual results. The spreadsheets are used as an independent check for several types of rad...

journal_title：Physics in medicine and biology

authors： Balog JP,Sibata CH,Podgorsak MB,Shin KH

更新日期：1995-06-01 00:00:00

abstract：:Respiratory gating can reduce the apparent respiratory motion during imaging and treatment; however, residual motion within the gating window remains. Respiratory training can improve respiratory reproducibility and, therefore, the efficacy of respiratory-gated radiotherapy. This study was conducted to determine wheth...

journal_title：Physics in medicine and biology

authors： George R,Ramakrishnan V,Siebers JV,Chung TD,Keall PJ

更新日期：2006-10-21 00:00:00

abstract：:A novel radiation targeted therapy is investigated for HER-2 positive breast cancers. The proposed concept combines two known approaches, but never used together for the treatment of advanced, relapsed or metastasized HER-2 positive breast cancers. The proposed radiation binary targeted concept is based on the anti HE...

journal_title：Physics in medicine and biology

authors： Mundy DW,Harb W,Jevremovic T

更新日期：2006-03-21 00:00:00

abstract：:We have developed a model using Monte Carlo methods to simulate x-ray mammography. All possible physical processes of interaction of x-rays with matter have been taken into account. A simplified geometry of the mammographic apparatus has been considered along with a software phantom of compressed breast. The phantom m...

journal_title：Physics in medicine and biology

authors： Spyrou G,Tzanakos G,Bakas A,Panayiotakis G

更新日期：1998-11-01 00:00:00

abstract：:W (the average energy to form an ion pair) for 5.4 MeV 241Am alpha particles in a Rossi-type tissue-equivalent (TE) gas, argon and methane was determined to an accuracy better than 0.2% using a new automated data handling system. A vibrating reed electrometer and current digitiser were used to measure the current prod...

journal_title：Physics in medicine and biology

authors： Krieger GL,Baum JW,Varma MN,Beach JL

更新日期：1979-03-01 00:00:00