Sparse-view x-ray CT reconstruction via total generalized variation regularization.

Abstract:

:Sparse-view CT reconstruction algorithms via total variation (TV) optimize the data iteratively on the basis of a noise- and artifact-reducing model, resulting in significant radiation dose reduction while maintaining image quality. However, the piecewise constant assumption of TV minimization often leads to the appearance of noticeable patchy artifacts in reconstructed images. To obviate this drawback, we present a penalized weighted least-squares (PWLS) scheme to retain the image quality by incorporating the new concept of total generalized variation (TGV) regularization. We refer to the proposed scheme as 'PWLS-TGV' for simplicity. Specifically, TGV regularization utilizes higher order derivatives of the objective image, and the weighted least-squares term considers data-dependent variance estimation, which fully contribute to improving the image quality with sparse-view projection measurement. Subsequently, an alternating optimization algorithm was adopted to minimize the associative objective function. To evaluate the PWLS-TGV method, both qualitative and quantitative studies were conducted by using digital and physical phantoms. Experimental results show that the present PWLS-TGV method can achieve images with several noticeable gains over the original TV-based method in terms of accuracy and resolution properties.

journal_name

Phys Med Biol

authors

Niu S,Gao Y,Bian Z,Huang J,Chen W,Yu G,Liang Z,Ma J

doi

10.1088/0031-9155/59/12/2997

subject

Has Abstract

pub_date

2014-06-21 00:00:00

pages

2997-3017

issue

12

eissn

0031-9155

issn

1361-6560

journal_volume

59

pub_type

杂志文章
  • The dosimetric impact of dental implants on head-and-neck volumetric modulated arc therapy.

    abstract::This work aims to investigate the dosimetric impact of dental implants on volumetric modulated arc therapy (VMAT) for head-and-neck patients and to evaluate the effectiveness of using the material's electron-density ratio for the correction. An in-house Monte Carlo (MC) code was utilized for the dose calculation to ac...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/58/4/1027

    authors: Lin MH,Li J,Price RA Jr,Wang L,Lee CC,Ma CM

    更新日期:2013-02-21 00:00:00

  • Female pelvic synthetic CT generation based on joint intensity and shape analysis.

    abstract::Using MRI for radiotherapy treatment planning and image guidance is appealing as it provides superior soft tissue information over CT scans and avoids possible systematic errors introduced by aligning MR to CT images. This study presents a method that generates Synthetic CT (MRCT) volumes by performing probabilistic t...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/62/8/2935

    authors: Liu L,Jolly S,Cao Y,Vineberg K,Fessler JA,Balter JM

    更新日期:2017-04-21 00:00:00

  • PETSIM: Monte Carlo simulation of all sensitivity and resolution parameters of cylindrical positron imaging systems.

    abstract::Monte Carlo simulation techniques are applied to track the annihilation photons from positron decay, and store the photon histories. Reasonably realistic models of the isotope distribution in the brain and heart during typical PET studies, as well as the traditional phantoms used for measuring PET scanner performance ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/37/3/017

    authors: Thompson CJ,Moreno-Cantu J,Picard Y

    更新日期:1992-03-01 00:00:00

  • Acquiring a four-dimensional computed tomography dataset using an external respiratory signal.

    abstract::Four-dimensional (4D) methods strive to achieve highly conformal radiotherapy, particularly for lung and breast tumours, in the presence of respiratory-induced motion of tumours and normal tissues. Four-dimensional radiotherapy accounts for respiratory motion during imaging, planning and radiation delivery, and requir...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/48/1/304

    authors: Vedam SS,Keall PJ,Kini VR,Mostafavi H,Shukla HP,Mohan R

    更新日期:2003-01-07 00:00:00

  • Automated prostate segmentation in whole-body MRI scans for epidemiological studies.

    abstract::The whole prostatic volume (PV) is an important indicator for benign prostate hyperplasia. Correlating the PV with other clinical parameters in a population-based prospective cohort study (SHIP-2) requires valid prostate segmentation in a large number of whole-body MRI scans. The axial proton density fast spin echo fa...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/58/17/5899

    authors: Habes M,Schiller T,Rosenberg C,Burchardt M,Hoffmann W

    更新日期:2013-09-07 00:00:00

  • Dose effect of guidewire position in intravascular brachytherapy.

    abstract::It has been reported that the dose effects of metallic guidewires are significant in intravascular brachytherapy (IVBT) using a beta source. The purpose of this work is to investigate the dependence of these dose effects on guidewire position. The EGS4 Monte Carlo codes were used to perform the dose calculations for t...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/47/10/309

    authors: Shih R,Hsu WL,Li XA

    更新日期:2002-05-21 00:00:00

  • Direct detection of 6 MV x-rays from a medical linear accelerator using a semiconducting polymer diode.

    abstract::Recently, a new family of low-cost x-radiation detectors have been developed, based on semiconducting polymer diodes, which are easy to process, mechanically flexible, relatively inexpensive, and able to cover large areas. To test their potential for radiotherapy applications such as beam monitors or dosimeters, as an...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/58/13/4471

    authors: Mills CA,Chan YF,Intaniwet A,Shkunov M,Nisbet A,Keddie JL,Sellin PJ

    更新日期:2013-07-07 00:00:00

  • Recovering the triple coincidence of non-pure positron emitters in preclinical PET.

    abstract::Non-pure positron emitters, with their long half-lives, allow for the tracing of slow biochemical processes which cannot be adequately examined by the commonly used short-lived positron emitters. Most of these isotopes emit high-energy cascade gamma rays in addition to positron decay that can be detected and create a ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/61/5/1904

    authors: Lin HH,Chuang KS,Chen SY,Jan ML

    更新日期:2016-03-07 00:00:00

  • Prediction of dose-volume histograms in nasopharyngeal cancer IMRT using geometric and dosimetric information.

    abstract::A method using both patient geometric and dosimetric information was proposed to predict dose-volume histograms (DVHs) of organs at risk (OARs) for a nasopharyngeal cancer (NPC) intensity-modulated radiation therapy (IMRT) plan. A total of 106 nine-field IMRT NPC plans were used in this study. Twenty-six plans were ra...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab50eb

    authors: Jiao SX,Chen LX,Zhu JH,Wang ML,Liu XW

    更新日期:2019-12-05 00:00:00

  • Optical artefact characterization and correction in volumetric scintillation dosimetry.

    abstract::The goals of this study were (1) to characterize the optical artefacts affecting measurement accuracy in a volumetric liquid scintillator detector, and (2) to develop methods to correct for these artefacts. The optical artefacts addressed were photon scattering, refraction, camera perspective, vignetting, lens distort...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/59/1/23

    authors: Robertson D,Hui C,Archambault L,Mohan R,Beddar S

    更新日期:2014-01-06 00:00:00

  • A phantom for the testing and calibration of near infra-red spectrometers.

    abstract::This note describes a simple phantom which can be used to check the long term stability and accuracy of relative attenuation measurements made by near infra-red (NIR) spectrometers. The phantom has been calibrated, and the results of the calibration are shown to agree with theoretical predictions of the relative atten...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/39/9/015

    authors: Firbank M,Delpy DT

    更新日期:1994-09-01 00:00:00

  • Generalised use of contrast degradation and contrast improvement factors in diagnostic radiology. Application to vanishing contrast.

    abstract::Although field area and object thickness are important parameters in comparisons of techniques for optimal reduction of scattered radiation to the image, they are in practice seldom varied. For this reason, we suggest that contrast degradation (CDF) and contrast improvement (CIF) factors be more frequently used and ap...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/31/7/004

    authors: Carlsson GA,Carlsson CA,Nielsen B,Persliden J

    更新日期:1986-07-01 00:00:00

  • Numerical considerations for interface reflections in medical ultrasound.

    abstract::The original concept of the echo mechanism in diagnostic medical ultrasound--of step impedance discontinuities--is investigated in terms of the numerical implications of more refined models. The effect of a discontinuity in the attenuation coefficients is found to have as much significance as the impedance discontinui...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/31/8/001

    authors: Chivers RC,Santosa F

    更新日期:1986-08-01 00:00:00

  • Hysteresis heating for the treatment of tumours.

    abstract::A method is described whereby, utilising a biocompatible magnetic glass-ceramic material, effective hysteresis heating in living tissue was accomplished. Initial experiments on mice showed that a significant heating effect can be obtained in the ceramic-impregnated regions. An analysis is also given for the projected ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/29/5/001

    authors: Borrelli NF,Luderer AA,Panzarino JN

    更新日期:1984-05-01 00:00:00

  • An automatic algorithm to exploit the symmetries of the system response matrix in positron emission tomography iterative reconstruction.

    abstract::Positron emission tomography (PET) iterative 3D reconstruction is a very computational demanding task. One of the main issues of the iterative reconstruction concerns the management of the system response matrix (SRM). The SRM models the relationship between the projection and the voxel space and its memory footprint ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aae12b

    authors: Camarlinghi N,Sportelli G,Guerra AD,Belcari N

    更新日期:2018-09-28 00:00:00

  • Optimizing functional parameter accuracy for breath-hold DCE-MRI of liver tumours.

    abstract::Dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) is a valuable tool for assessing treatment response to novel cancer therapeutics. With appropriate data acquisition, quantitative functional parameter estimates can be obtained by fitting a model to the data. This research focuses on applying a dual-input ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/54/7/023

    authors: Orton MR,Miyazaki K,Koh DM,Collins DJ,Hawkes DJ,Atkinson D,Leach MO

    更新日期:2009-04-07 00:00:00

  • Full-field speckle interferometry for non-contact photoacoustic tomography.

    abstract::A full-field speckle interferometry method for non-contact and prospectively high speed Photoacoustic Tomography is introduced and evaluated as proof of concept. Thermoelastic pressure induced changes of the objects topography are acquired in a repetitive mode without any physical contact to the object. In order to ob...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/10/4045

    authors: Horstmann J,Spahr H,Buj C,Münter M,Brinkmann R

    更新日期:2015-05-21 00:00:00

  • A framework for organ dose estimation in x-ray angiography and interventional radiology based on dose-related data in DICOM structured reports.

    abstract::Although interventional x-ray angiography (XA) procedures involve relatively high radiation doses that can lead to deterministic tissue reactions in addition to stochastic effects, convenient and accurate estimation of absorbed organ doses has traditionally been out of reach. This has mainly been due to the absence of...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/61/8/3063

    authors: Omar A,Bujila R,Fransson A,Andreo P,Poludniowski G

    更新日期:2016-04-21 00:00:00

  • Calculation of water equivalent ratios for various materials at proton energies ranging 10-500 MeV using MCNP, FLUKA, and GEANT4 Monte Carlo codes.

    abstract::Dosimetry of proton beams is generally evaluated in liquid water, or alternatively in solid phantoms via water equivalent ratios (WER). WER is defined as the ratio of proton range in liquid water to that in a phantom of certain material. Presently, WER is not available in the literature neither for a wide range of ene...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aad0bd

    authors: Safigholi H,Song WY

    更新日期:2018-07-27 00:00:00

  • FBP-Net for direct reconstruction of dynamic PET images.

    abstract::Dynamic positron emission tomography (PET) imaging can provide information about metabolic changes over time, used for kinetic analysis and auxiliary diagnosis. Existing deep learning-based reconstruction methods have too many trainable parameters and poor generalization, and require mass data to train the neural netw...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/abc09d

    authors: Wang B,Liu H

    更新日期:2020-10-13 00:00:00

  • Global point signature for shape analysis of carpal bones.

    abstract::We present a method based on spectral theory for the shape analysis of carpal bones of the human wrist. We represent the cortical surface of the carpal bone in a coordinate system based on the eigensystem of the two-dimensional Helmholtz equation. We employ a metric--global point signature (GPS)--that exploits the sca...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/59/4/961

    authors: Chaudhari AJ,Leahy RM,Wise BL,Lane NE,Badawi RD,Joshi AA

    更新日期:2014-02-21 00:00:00

  • Contactless remote induction of shear waves in soft tissues using a transcranial magnetic stimulation device.

    abstract::This study presents the first observation of shear waves induced remotely within soft tissues. It was performed through the combination of a transcranial magnetic stimulation device and a permanent magnet. A physical model based on Maxwell and Navier equations was developed. Experiments were performed on a cryogel pha...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/61/6/2582

    authors: Grasland-Mongrain P,Miller-Jolicoeur E,Tang A,Catheline S,Cloutier G

    更新日期:2016-03-21 00:00:00

  • Exact reconstruction in 2D dynamic CT: compensation of time-dependent affine deformations.

    abstract::This work is dedicated to the reduction of reconstruction artefacts due to motion occurring during the acquisition of computerized tomographic projections. This problem has to be solved when imaging moving organs such as the lungs or the heart. The proposed method belongs to the class of motion compensation algorithms...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/49/11/004

    authors: Roux S,Desbat L,Koenig A,Grangeat P

    更新日期:2004-06-07 00:00:00

  • Evaluation of a ferrous benzoic xylenol orange transparent PVA cryogel radiochromic dosimeter.

    abstract::A stable cryogel dosimeter was prepared using ferrous benzoic xylenol orange (FBX) in a transparent poly-(vinyl alcohol) (PVA) cryogel matrix. Dose response was evaluated for different numbers of freeze-thaw cycles (FTCs), different concentrations of PVA, and ratios of water/dimethyl sulfoxide. Linear relationships be...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/59/7/1773

    authors: Eyadeh MM,Farrell TJ,Diamond KR

    更新日期:2014-04-07 00:00:00

  • Physics of contrast mechanism and averaging effect of linear attenuation coefficients in a computerized transverse axial tomography CTAT) transmission scanner.

    abstract::Detailed studies of the basic contrast mechanisms in computerized transverse axial tomography scanners have been carried out. Contrast is related to the effective atomic numbers and electron densities of materials and the resultant linear attenuation coefficients. We have therefore quantitatively evaluated various sam...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/21/4/006

    authors: Tsai CM,Cho ZH

    更新日期:1976-07-01 00:00:00

  • Relative Patlak plot for dynamic PET parametric imaging without the need for early-time input function.

    abstract::The Patlak graphical method is widely used in parametric imaging for modeling irreversible radiotracer kinetics in dynamic PET. The net influx rate of radiotracer can be determined from the slope of the Patlak plot. The implementation of the standard Patlak method requires the knowledge of full-time input function fro...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aad444

    authors: Zuo Y,Qi J,Wang G

    更新日期:2018-08-10 00:00:00

  • Optimization of a depth of interaction encoding PET block detector for a PET/MRI insert.

    abstract::Preclinical positron emission tomography, combined with magnetic resonance imaging (PET/MRI), is increasingly used as a tool to simultaneously characterize functional processes in vivo. Many emerging preclinical applications, however, are limited by PET detection sensitivity, especially when generating short imaging f...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aaef59

    authors: Selfridge AR,Cherry SR,Judenhofer MS

    更新日期:2018-12-06 00:00:00

  • Estimation of percentage body fat by dual-energy x-ray absorptiometry: evaluation by in vivo human elemental composition.

    abstract::Dual-energy x-ray absorptiometry (DXA) is widely applied for estimating body fat. The percentage of body mass as fat (%fat) is predicted from a DXA-estimated R(ST) value defined as the ratio of soft tissue attenuation at two photon energies (e.g., 40 keV and 70 keV). Theoretically, the R(ST) concept depends on the mas...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/55/9/013

    authors: Wang Z,Heymsfield SB,Chen Z,Zhu S,Pierson RN

    更新日期:2010-05-07 00:00:00

  • A unified analysis of FBP-based algorithms in helical cone-beam and circular cone- and fan-beam scans.

    abstract::A circular scanning trajectory is and will likely remain a popular choice of trajectory in computed tomography (CT) imaging because it is easy to implement and control. Filtered-backprojection (FBP)-based algorithms have been developed previously for approximate and exact reconstruction of the entire image or a region...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/49/18/011

    authors: Pan X,Xia D,Zou Y,Yu L

    更新日期:2004-09-21 00:00:00

  • Hybrid scatter correction applied to quantitative holmium-166 SPECT.

    abstract::Ho-166 is a combined beta-gamma emitter of which the betas can be used therapeutically. From the 81 keV gammas of Ho-166, SPECT images can be obtained, which give opportunities to guide Ho-166 therapy. Accurate reconstruction of Ho-166 images is currently hampered by photopeak-scatter in the patient, down-scatter in t...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/51/19/004

    authors: de Wit TC,Xiao J,Nijsen JF,van het Schip FD,Staelens SG,van Rijk PP,Beekman FJ

    更新日期:2006-10-07 00:00:00