Abstract:
:Although field area and object thickness are important parameters in comparisons of techniques for optimal reduction of scattered radiation to the image, they are in practice seldom varied. For this reason, we suggest that contrast degradation (CDF) and contrast improvement (CIF) factors be more frequently used and appropriately defined to make the dependence of CDF and CIF on field area (collimation) and object thickness (compression) explicit. Definitions are formulated and the results of experiments and Monte Carlo calculations (comprising effects of collimation, compression, air gap, antiscatter grid, detector thickness) cited to illustrate their usefulness. Currently used expressions for CIF (derived assuming monoenergetic radiation) lack a factor to account for the change in primary contrast caused by the antiscatter method when this affects the energy distribution of the transmitted primary photons (grids and compression) or the fractions of photon energy imparted to the detector (when comparing different detectors). Values of this factor are calculated for some cases. Also, the appropriate choice of physical quantity to be used in the formulae for CDF and CIF is discussed. The energy imparted to the detector is advocated since this is directly related to the detector signals forming the image on, e.g. the x-ray film.
journal_name
Phys Med Bioljournal_title
Physics in medicine and biologyauthors
Carlsson GA,Carlsson CA,Nielsen B,Persliden Jdoi
10.1088/0031-9155/31/7/004subject
Has Abstractpub_date
1986-07-01 00:00:00pages
737-49issue
7eissn
0031-9155issn
1361-6560journal_volume
31pub_type
杂志文章abstract::To increase the scanning speed of cone-beam CT, a scanning configuration with three pairs of x-ray sources and panel detectors was proposed. In this paper, we apply the M-line-based backprojected filtration algorithm to this scanning configuration and propose a fast implementation for this algorithm. Compared with exi...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/55/23/009
更新日期:2010-12-07 00:00:00
abstract::Using Cherenkov radiation in positron emission tomography (PET) has the potential to improve the time of flight (TOF) resolution and reduce the cost of detectors. In previous studies promising TOF results were achieved when lead fluoride (PbF2) crystals were used instead of a scintillator. In this work, a whole-body P...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/1361-6560/ab6f97
更新日期:2020-03-06 00:00:00
abstract::Computational modeling is an important tool in ultrasound imaging research, but realistic three-dimensional (3D) simulations can exceed the capabilities of serial computers. This paper uses a 3D simulator based on a k-space method that incorporates relaxation absorption and nonreflecting boundary conditions. The simul...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/54/17/007
更新日期:2009-09-07 00:00:00
abstract::Results from dielectric studies on the freshwater fish Cyprinus carpio exposed to a sublethal concentration of sodium alkyl benzene sulphonate were compared with those from untreated control fish; recovery from the test solution was also checked. The influence of the anionic detergent on the intracellular matter of fi...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/29/5/005
更新日期:1984-05-01 00:00:00
abstract::Changes in the relative biological effectiveness (RBE) of the radiation-induced cell killing of human salivary glands (HSG) were assessed along the Bragg peak of a 60 MeV clinical proton beam by means of coupling biophysical models with the results of Monte Carlo radiation transport simulations and experimental measur...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/1361-6560/ab491f
更新日期:2020-01-10 00:00:00
abstract::We investigate the effect of multiple scattering on the optical coherence tomography (OCT) signal and the Doppler OCT signal of flowing blood. Doppler OCT measurements at 1300 nm are performed on flowing diluted porcine blood with hematocrit ranging between 0% and 15%. Measured blood hematocrit and mean red blood cell...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/57/7/1907
更新日期:2012-04-07 00:00:00
abstract::The spatial resolution of 2D detector arrays equipped with ionization chambers or diodes, used for the dose verification of IMRT treatment plans, is limited by the size of the single detector and the centre-to-centre distance between the detectors. Optimization criteria with regard to these parameters have been develo...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/52/10/019
更新日期:2007-05-21 00:00:00
abstract::A circular scanning trajectory is and will likely remain a popular choice of trajectory in computed tomography (CT) imaging because it is easy to implement and control. Filtered-backprojection (FBP)-based algorithms have been developed previously for approximate and exact reconstruction of the entire image or a region...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/49/18/011
更新日期:2004-09-21 00:00:00
abstract::The advent of real-time ultrasound in the 1970s, together with a growing interest in tissue characterization, led to a number of investigators using the nature of tissue motion to distinguish healthy from diseased tissue. Our group at the (then) Ultrasonics Institute demonstrated the use of phase methods for detecting...
journal_title:Physics in medicine and biology
pub_type: 历史文章,杂志文章
doi:10.1088/0031-9155/45/6/301
更新日期:2000-06-01 00:00:00
abstract::We have measured the bulk optical properties of healthy female breast tissues in vivo in the parallel plate, transmission geometry. Fifty-two volunteers were measured. Blood volume and blood oxygen saturation were derived from the optical property data using a novel method that employed a priori spectral information t...
journal_title:Physics in medicine and biology
pub_type: 临床试验,杂志文章
doi:10.1088/0031-9155/47/16/302
更新日期:2002-08-21 00:00:00
abstract::In recent years, particle therapy has become a widely accepted form of cancer treatment and technological advances in beam delivery technology (i.e. pencil beam scanning (PBS)) have enabled the application of highly conformal dose distributions to static targets. Current research focuses on the possibilities for the t...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/58/22/7905
更新日期:2013-11-21 00:00:00
abstract::A mathematical procedure, using Fourier deconvolution, is described whereby diffusion-free proximity functions can be obtained from cloud-chamber data. Such non-diffused distributions can be used to obtain further microdosimetric and nanodosimetric quantities hitherto not available from experiments, thus making the cl...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/33/11/004
更新日期:1988-11-01 00:00:00
abstract::The theory of task-based assessment of image quality is reviewed in the context of imaging with ionizing radiation, and objective figures of merit (FOMs) for image quality are summarized. The variation of the FOMs with the task, the observer and especially with the mean number of photons recorded in the image is discu...
journal_title:Physics in medicine and biology
pub_type: 杂志文章,评审
doi:10.1088/0031-9155/60/2/R1
更新日期:2015-01-21 00:00:00
abstract::The UK, European and IAEA protocols for breast dosimetry in mammography use tabulations of conversion factors, which relate measurements of incident air kerma to the mean glandular dose to the breast. To supplement the existing tabulations, a Monte Carlo computer program has been used to calculate conversion factors f...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/59/9/2127
更新日期:2014-05-07 00:00:00
abstract::Several studies have been appeared, up to now, that indicate the effect of accurate simulation on dose received by different substructures of the eye, irradiated by external beams of short-range radiation such as electron. Different representations of the eye have consequently been introduced. Their accuracies depend ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/1361-6560/ab2059
更新日期:2019-07-02 00:00:00
abstract::In this note, we present the first experimental results of in-beam PET measurements during high energy photon phantom irradiation. An inhomogeneous phantom was irradiated with pulsed 34 MV bremsstrahlung. The measurements have been conducted with a dedicated double head positron camera. A high material contrast could ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/52/20/N01
更新日期:2007-10-21 00:00:00
abstract::Over the last decade, the performance of benchtop x-ray fluorescence computed tomography (XFCT) systems has been significantly enhanced through hardware and software optimizations. Recent studies have indicated the need of energy-resolving pixelated/array detectors in the x-ray detection component to further improve t...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/1361-6560/ab9774
更新日期:2020-08-31 00:00:00
abstract::Radiotherapy treatment planning relies on the use of geometrically correct images. This paper presents a fully automatic tool for correcting MR images for the effects of B(0) inhomogeneities. The post-processing method is based on the gradient-reversal technique of Chang and Fitzpatrick (1992 IEEE Trans. Med. Imaging ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/50/11/014
更新日期:2005-06-07 00:00:00
abstract::In interstitial heating one of the main requirements for achieving a certain elevated temperature in a tumour is that the effective power per applicator (Peff), i.e. the power which is actually deposited in the tissue, is sufficiently high. In this paper this requirement is discussed for the applicators of the 27 MHz ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/42/6/007
更新日期:1997-06-01 00:00:00
abstract::A novel transmission detector (IBA Dosimetry, Germany) developed as an IMRT quality assurance tool, intended for in vivo patient dose measurements, is studied here. The goal of this investigation is to use Monte Carlo techniques to characterize treatment beam parameters in the presence of the detector and to compare t...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/56/4/020
更新日期:2011-02-21 00:00:00
abstract::In radiotherapy with photon beams, the use of dynamic wedges, which are obtained by the movement of one of the jaws, offers an increasing flexibility relative to the traditional use of metal wedges. But it is a disadvantage for the measurement of absorbed dose distributions, because the absorbed dose at each measureme...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/43/6/009
更新日期:1998-06-01 00:00:00
abstract::Simultaneous thermoradiotherapy has been shown to maximize the effect of hyperthermia as a radiation sensitizer in cancer treatment. Here we follow our previous work on feasibility of thermoradiotherapy with the scanning ultrasound reflector linear array system (SURLAS) and TomoTherapy HiArt treatment system, and inve...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/53/10/004
更新日期:2008-05-21 00:00:00
abstract::Online proton range/dose verification based on measurements of proton-induced positron emitters is a promising strategy for quality assurance in proton therapy. Because of the nonlinear correlation between the dose distribution and the activity distribution of positron emitters, we aim to establish their relationship ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/1361-6560/ab3564
更新日期:2019-09-04 00:00:00
abstract::An X-ray technique has been developed to enable reproducible and quantitative data to be obtained from radiographs taken by a diagnostic X-ray machine. Careful attention has been paid to the alignment of the specimen and the diagnostic tube and to operating conditions. The choice of X-ray spectrum is described togethe...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/22/4/003
更新日期:1977-07-01 00:00:00
abstract::The treatment delivery time of intensity-modulated radiation therapy (IMRT) with a multileaf collimator (MLC) is generally longer than that of conventional radiotherapy. In theory, removing the flattening filter from the treatment head may reduce the beam-on time by enhancing the output dose rate, and then reduce the ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/49/8/011
更新日期:2004-04-21 00:00:00
abstract::In this study, the safety compliance for nonuniform field exposures is discussed using coupling factor concepts. The coupling factor, which is defined in the International Electrotechnical Commission 62311 standard, is extended to consider the effects of harmonics and also to apply to the specific absorption rate (for...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/60/20/8129
更新日期:2015-10-21 00:00:00
abstract::A single photon absorptiometry method to measure the arterial concentration of injected iodinated contrast agent was developed. A prototype absorptiometry unit was built which consists of either a square or circular cross section acrylic (polymethylmethacrylate) cuvette connected to an arterial catheter at one end and...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/37/9/002
更新日期:1992-09-01 00:00:00
abstract::The UMC Utrecht is constructing a 1.5 T MRI scanner integrated with a linear accelerator (Lagendijk et al 2008 Radiother. Oncol. 86 25-9). The goal of this device is to facilitate soft-tissue contrast based image-guided radiotherapy, in order to escalate the dose to the tumour while sparing surrounding normal tissues....
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/54/10/002
更新日期:2009-05-21 00:00:00
abstract::As an x-ray beam goes through the human body, it will collect important information via interaction with tissues. Since this interaction is energy-sensitive, the state-of-the-art spectral CT technologies provide higher quality images of biological tissues with x-ray energy information (or spectral information). With e...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/61/11/4183
更新日期:2016-06-07 00:00:00
abstract::In treatment planning we depend upon accurate knowledge of geometric and range uncertainties. If the uncertainty model is inaccurate then the plan will produce under-dosing of the target and/or overdosing of OAR. We aim to provide a method for which centre and site-specific population range uncertainty due to inter-fr...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/1361-6560/aa9502
更新日期:2017-12-19 00:00:00