Automated prostate segmentation in whole-body MRI scans for epidemiological studies.

Abstract:

:The whole prostatic volume (PV) is an important indicator for benign prostate hyperplasia. Correlating the PV with other clinical parameters in a population-based prospective cohort study (SHIP-2) requires valid prostate segmentation in a large number of whole-body MRI scans. The axial proton density fast spin echo fat saturated sequence is used for prostate screening in SHIP-2. Our automated segmentation method is based on support vector machines (SVM). We used three-dimensional neighborhood information to build classification vectors from automatically generated features and randomly selected 16 MR examinations for validation. The Hausdorff distance reached a mean value of 5.048 ± 2.413, and a mean value of 5.613 ± 2.897 compared to manual segmentation by observers A and B. The comparison between volume measurement of SVM-based segmentation and manual segmentation of observers A and B depicts a strong correlation resulting in Spearman's rank correlation coefficients (ρ) of 0.936 and 0.859, respectively. Our automated methodology based on SVM for prostate segmentation can segment the prostate in WBI scans with good segmentation quality and has considerable potential for integration in epidemiological studies.

journal_name

Phys Med Biol

authors

Habes M,Schiller T,Rosenberg C,Burchardt M,Hoffmann W

doi

10.1088/0031-9155/58/17/5899

subject

Has Abstract

pub_date

2013-09-07 00:00:00

pages

5899-915

issue

17

eissn

0031-9155

issn

1361-6560

journal_volume

58

pub_type

杂志文章
  • Intravascular brachytherapy of the coronary arteries.

    abstract::This is a review of the relatively recently developed field of intravascular brachytherapy of coronary arteries. It presents a brief overview of the discipline of coronary angioplasty describing the problem of restenosis and discusses the potential for ionizing radiation to overcome this problem. It examines the vario...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1088/0031-9155/47/4/201

    authors: Fox RA

    更新日期:2002-02-21 00:00:00

  • Online compensation for target motion with scanned particle beams: simulation environment.

    abstract::Target motion is one of the major limitations of each high precision radiation therapy. Using advanced active beam delivery techniques, such as the magnetic raster scanning system for particle irradiation, the interplay between time-dependent beam and target position heavily distorts the applied dose distribution. Thi...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/49/14/001

    authors: Li Q,Groezinger SO,Haberer T,Rietzel E,Kraft G

    更新日期:2004-07-21 00:00:00

  • Theoretical modeling of yields for proton-induced reactions on natural and enriched molybdenum targets.

    abstract::Recent acute shortage of medical radioisotopes prompted investigations into alternative methods of production and the use of a cyclotron and ¹⁰⁰Mo(p,2n)(99m)Tc reaction has been considered. In this context, the production yields of (99m)Tc and various other radioactive and stable isotopes which will be created in the ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/56/17/002

    authors: Celler A,Hou X,Bénard F,Ruth T

    更新日期:2011-09-07 00:00:00

  • A novel description of FDG excretion in the renal system: application to metformin-treated models.

    abstract::This paper introduces a novel compartmental model describing the excretion of 18F-fluoro-deoxyglucose (FDG) in the renal system and a numerical method based on the maximum likelihood for its reduction. This approach accounts for variations in FDG concentration due to water re-absorption in renal tubules and the increa...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/59/10/2469

    authors: Garbarino S,Caviglia G,Sambuceti G,Benvenuto F,Piana M

    更新日期:2014-05-21 00:00:00

  • Influence of sulphuric acid contaminants on Fricke dosimetry.

    abstract::The sulphuric acid used for the preparation of the Fricke dosimeter solution may contain trace impurities that can affect the yield of ferric ions. Two methods, pre-irradiation or oxidation with hydrogen peroxide, have been proposed to reduce the influence of these impurities. Fricke users sometimes omit this treatmen...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/45/9/403

    authors: Palm A,Mattsson O

    更新日期:2000-09-01 00:00:00

  • Counting losses in multidetector radiation counters.

    abstract::We examined the reasons for the reduction in response of a multidetector radiation counting system when operated at high count-rates and established a convenient method of correction which is accurate to within +/- 1% up to 0-6 X 10(5) counts per second. In its application the method uses the observed count-rates from...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/21/1/009

    authors: Oxby CB,Oldroyd B,Appleby DB

    更新日期:1976-01-01 00:00:00

  • Correction of proton resonance frequency shift temperature maps for magnetic field disturbances caused by breathing.

    abstract::Respiratory induced resonance offset (RIRO) is a periodic disturbance of a magnetic field due to breathing. Such disturbance handicaps the accuracy of the proton resonance frequency shift (PRFS) method of MRI temperature mapping in anatomies situated nearby the lungs and chest wall. In this work, we propose a method c...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/51/18/015

    authors: Shmatukha AV,Bakker CJ

    更新日期:2006-09-21 00:00:00

  • Analysis on reversible/irreversible electroporation region in lung adenocarcinoma cell modelin vitrowith electric pulses delivered by needle electrodes.

    abstract::Irreversible electroporation (IRE) is a minimally invasive tumor therapy using pulsed electric field with high intensity while the important tissues such as blood vessel, bile duct, and nerve are preserved. In addition to ablation area, reversible electroporation (RE) region is also generated using needle electrodes f...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/abc12e

    authors: Lv Y,Tang X,Peng W,Cheng X,Chen S,Yao C

    更新日期:2020-10-14 00:00:00

  • Diaphragm correction factors for free-air chamber standards for air kerma in x-rays.

    abstract::At present, only a correction factor for photon transmission, k(l), is systematically applied for the entrance diaphragm of free-air chamber standards for air kerma. In the present work, the Monte Carlo code PENELOPE is used to re-evaluate k(l) for the BIPM standards and new correction factors are calculated for photo...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/54/9/009

    authors: Burns DT,Kessler C

    更新日期:2009-05-07 00:00:00

  • Comparison of temperature distributions in interstitial hyperthermia: experiments in bovine tongues versus generic simulations.

    abstract::Temperature distributions resulting from hyperthermia treatments on isolated perfused bovine tongues were compared with simulations by a treatment planning system. The aim was to test whether the discrete vessel model used for the treatment planning is able to predict correct generic temperature distributions. Tongues...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/43/5/011

    authors: Raaymakers BW,Crezee J,Lagendijk JJ

    更新日期:1998-05-01 00:00:00

  • Direct 4D reconstruction of parametric images incorporating anato-functional joint entropy.

    abstract::We developed an anatomy-guided 4D closed-form algorithm to directly reconstruct parametric images from projection data for (nearly) irreversible tracers. Conventional methods consist of individually reconstructing 2D/3D PET data, followed by graphical analysis on the sequence of reconstructed image frames. The propose...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/55/15/005

    authors: Tang J,Kuwabara H,Wong DF,Rahmim A

    更新日期:2010-08-07 00:00:00

  • Characterization of noise and background signals in a magnetic particle imaging system.

    abstract::Magnetic Particle Imaging (MPI) is a novel technology, which opens new possibilities for promising biomedical applications. MPI uses magnetic fields to generate a specific response from magnetic nanoparticles (MNPs), to determine their spatial location non-invasively and without using ionizing radiation. One open chal...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/abc364

    authors: Paysen H,Kosch O,Wells J,Loewa N,Wiekhorst F

    更新日期:2020-10-21 00:00:00

  • Limitations of clinical CT in assessing cortical thickness and density.

    abstract::The peak CT number (CT) and full width at half maximum (FWHM) were obtained from the image profiles of aluminium of thickness ranging from 0.1-9.5 mm. The scans were performed at different fields of view (FOVs) and with different reconstruction algorithms ('bone' and 'standard'). Above 3 mm, CT and FWHM provide measur...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/43/3/013

    authors: Newman DL,Dougherty G,al Obaid A,al Hajrasy H

    更新日期:1998-03-01 00:00:00

  • A revised monitor source method for practical deadtime count loss compensation in clinical planar and SPECT studies.

    abstract::The aim of the study is to verify the fundamental assumption in the monitor source method, i.e. uniform fractional count loss across the field of view (FOV), and to introduce a revised monitor source method for SPECT deadtime correction that minimally interferes with the clinical protocol. SPECT images of non-uniform ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/3/1199

    authors: Siman W,Silosky M,Kappadath SC

    更新日期:2015-02-07 00:00:00

  • A robust state-space kinetics-guided framework for dynamic PET image reconstruction.

    abstract::Dynamic PET image reconstruction is a challenging issue due to the low SNR and the large quantity of spatio-temporal data. We propose a robust state-space image reconstruction (SSIR) framework for activity reconstruction in dynamic PET. Unlike statistically-based frame-by-frame methods, tracer kinetic modeling is inco...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/56/8/010

    authors: Tong S,Alessio AM,Kinahan PE,Liu H,Shi P

    更新日期:2011-04-21 00:00:00

  • Evaluating attenuation correction strategies in a dedicated, single-gantry breast PET-tomosynthesis scanner.

    abstract::We are developing a dedicated, combined breast positron emission tomography (PET)-tomosynthesis scanner. Both the PET and digital breast tomosynthesis (DBT) scanners are integrated in a single gantry to provide spatially co-registered 3D PET-tomosynthesis images. The DBT image will be used to identify the breast bound...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/abc5a8

    authors: Krishnamoorthy S,Vent T,Barufaldi B,Maidment ADA,Karp JS,Surti S

    更新日期:2020-10-28 00:00:00

  • Image quality assessment in digital mammography: part II. NPWE as a validated alternative for contrast detail analysis.

    abstract::Assessment of image quality for digital x-ray mammography systems used in European screening programs relies mainly on contrast-detail CDMAM phantom scoring and requires the acquisition and analysis of many images in order to reduce variability in threshold detectability. Part II of this study proposes an alternative ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/56/14/003

    authors: Monnin P,Marshall NW,Bosmans H,Bochud FO,Verdun FR

    更新日期:2011-07-21 00:00:00

  • A three-dimensional model-based partial volume correction strategy for gated cardiac mouse PET imaging.

    abstract::Quantification in cardiac mouse positron emission tomography (PET) imaging is limited by the imaging spatial resolution. Spillover of left ventricle (LV) myocardial activity into adjacent organs results in partial volume (PV) losses leading to underestimation of myocardial activity. A PV correction method was develope...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/57/13/4309

    authors: Dumouchel T,Thorn S,Kordos M,DaSilva J,Beanlands RS,deKemp RA

    更新日期:2012-07-07 00:00:00

  • A temperature-based feedback control system for electromagnetic phased-array hyperthermia: theory and simulation.

    abstract::A hybrid proportional-integral-in-time and cost-minimizing-in-space feedback control system for electromagnetic, deep regional hyperthermia is proposed. The unique features of this controller are that (1) it uses temperature, not specific absorption rate, as the criterion for selecting the relative phases and amplitud...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/48/5/306

    authors: Kowalski ME,Jin JM

    更新日期:2003-03-07 00:00:00

  • Treatment time reduction for large thermal lesions by using a multiple 1D ultrasound phased array system.

    abstract::To generate large thermal lesions in ultrasound thermal therapy, cooling intermissions are usually introduced during the treatment to prevent near-field heating, which leads to a long treatment time. A possible strategy to shorten the total treatment time is to eliminate the cooling intermissions. In this study, the t...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/48/9/307

    authors: Liu HL,Chen YY,Yen JY,Lin WL

    更新日期:2003-05-07 00:00:00

  • Fully 3D iterative scatter-corrected OSEM for HRRT PET using a GPU.

    abstract::Accurate scatter correction is especially important for high-resolution 3D positron emission tomographies (PETs) such as high-resolution research tomograph (HRRT) due to large scatter fraction in the data. To address this problem, a fully 3D iterative scatter-corrected ordered subset expectation maximization (OSEM) in...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/56/15/021

    authors: Kim KS,Ye JC

    更新日期:2011-08-07 00:00:00

  • Microwave tomography for functional imaging of extremity soft tissues: feasibility assessment.

    abstract::It is important to assess the viability of extremity soft tissues, as this component is often the determinant of the final outcome of fracture treatment. Microwave tomography (MWT) and sensing might be able to provide a fast and mobile assessment of such properties. MWT imaging of extremities possesses a complicated, ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/52/18/015

    authors: Semenov S,Kellam J,Althausen P,Williams T,Abubakar A,Bulyshev A,Sizov Y

    更新日期:2007-09-21 00:00:00

  • Local hydrogen clearance as a method for the measurement of capillary blood flow.

    abstract::A hydrogen clearance technique for the measurement of capillary blood flow in skeletal muscle (both resting and working) and the beating heart in experimental animals is described. Various methods for introducing the hydrogen into the region of measurement are compared, together with the appropriate methods for evalua...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/34/10/005

    authors: Harrison DK,Kessler M

    更新日期:1989-10-01 00:00:00

  • Intermittent cryogen spray cooling for optimal heat extraction during dermatologic laser treatment.

    abstract::Fast heat extraction is critically important to obtain the maximal benefit of cryogen spray cooling (CSC) during laser therapy of shallow skin lesions, such as port wine stain birthmarks. However, a film of liquid cryogen can build up on the skin surface, impairing heat transfer due to the relatively low thermal condu...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/47/18/301

    authors: Majaron B,Svaasand LO,Aguilar G,Nelson JS

    更新日期:2002-09-21 00:00:00

  • Development and comparison of computer methods for organ motion correction in scintigraphy.

    abstract::The process of organ motion correction in scintigraphy is analysed in the frequency domain. The sequence of the chi- and gamma- coordinates registered during scintigraphic recording is converted to a frequency spectrum by a discrete Fourier transform. In the frequency domain motion correction is performed by linear fi...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/20/3/010

    authors: Schmidlin P

    更新日期:1975-05-01 00:00:00

  • Estimation of effective imaging dose for kilovoltage intratreatment monitoring of the prostate position during cancer radiotherapy.

    abstract::Kilovoltage intratreatment monitoring (KIM) is a novel real-time localization modality where the tumor position is continuously measured during intensity modulated radiation therapy (IMRT) or intensity modulated arc therapy (IMAT) by a kilovoltage (kV) x-ray imager. Adding kV imaging during therapy adds radiation dose...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/58/17/5983

    authors: Ng JA,Booth J,Poulsen P,Kuncic Z,Keall PJ

    更新日期:2013-09-07 00:00:00

  • MTF evaluation of a phosphor-coated CCD for x-ray imaging.

    abstract::A novel digital x-ray detector has been assembled. The imaging system is based on a phosphor-coated charge-coupled device (CCD) obtained by direct deposition of a gadolinium oxysulphide scintillator onto the detector surface. The modulation transfer function has been measured along the two directions of the digital co...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/41/12/016

    authors: Gambaccini M,Taibi A,Del Guerra A,Marziani M,Tuffanelli A

    更新日期:1996-12-01 00:00:00

  • Assessment of noise in a digital image using the join-count statistic and the Moran test.

    abstract::We assume that the data bits of a pixel in digital images can be divided into signal and noise bits. The signal bits occupy the most significant part of the pixel and the noise bits the least significant part. The signal part of each pixel are correlated while the noise parts are uncorrelated. Two statistical methods,...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/37/2/004

    authors: Chuang KS,Huang HK

    更新日期:1992-02-01 00:00:00

  • The quality of ionising radiations emitted by radionuclides incorporated into mammalian cells.

    abstract::Radionuclides which decay by electron capture accompanied by Auger electron cascades, or by beta emission are thought to be excessively damaging when incorporated into the molecular structure of mammalian cell nuclei and thereby pose a radiation hazard which is not assessable by conventional dosimetry. Survival data, ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/34/7/003

    authors: Younis AR,Watt DE

    更新日期:1989-07-01 00:00:00

  • Single and multiple cross sections for ionizing processes of biological molecules by protons and alpha-particle impact: a classical Monte Carlo approach.

    abstract::A classical trajectory model has been used to predict total cross sections of single and double ionizing processes (including capture processes) for several ion-biological molecule collisional systems in the intermediate and high energy range. In this work, the systems studied are water, adenine or cytosine targets io...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/53/4/N03

    authors: Abbas I,Champion C,Zarour B,Lasri B,Hanssen J

    更新日期:2008-02-21 00:00:00