Physics of contrast mechanism and averaging effect of linear attenuation coefficients in a computerized transverse axial tomography CTAT) transmission scanner.

Abstract:

:Detailed studies of the basic contrast mechanisms in computerized transverse axial tomography scanners have been carried out. Contrast is related to the effective atomic numbers and electron densities of materials and the resultant linear attenuation coefficients. We have therefore quantitatively evaluated various samples defined by these parameters. A multienergetic X-ray source causes resolution degrading problems arising from the averaging effect of the linear attenuation coefficients. The controversy regarding the use of fixed length water bath as a reference to compensate the spectral shift (hardening) effect of the multienergetic X-ray source is also analysed and reported. Computer simulations demonstrating the sensitivities of the linear attenuation coefficient measurements and errors, as functions of the energy spectrum, were made for representative cases. Simulation results indicate that by using a full water bath, artifacts stemming from the multienergetic X-ray souce can be significantly reduced. An alternative approach using a count rate equalizer, considered to be another way of reducing the wide dynamic range in count rate when a water bath is not used, is also studied and the results reported.

journal_name

Phys Med Biol

authors

Tsai CM,Cho ZH

doi

10.1088/0031-9155/21/4/006

subject

Has Abstract

pub_date

1976-07-01 00:00:00

pages

544-59

issue

4

eissn

0031-9155

issn

1361-6560

journal_volume

21

pub_type

杂志文章
  • Estimating photon interaction coefficients from single energy x-ray CT.

    abstract::Single energy x-ray analysis is explored in the context of computed tomography (CT), whereby Hounsfield numbers (HN) are used to estimate electron density N(e) and parameters that describe composition. We examine measurements with tissue substitute materials and theoretical HN for a broad range of tissues. Results are...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/57/23/8079

    authors: Midgley SM

    更新日期:2012-12-07 00:00:00

  • An extended diffraction-enhanced imaging method for implementing multiple-image radiography.

    abstract::Diffraction-enhanced imaging (DEI) is an analyser-based x-ray imaging method that produces separate images depicting the projected x-ray absorption and refractive properties of an object. Because the imaging model of DEI does not account for ultra-small-angle x-ray scattering (USAXS), the images produced in DEI can co...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/52/7/011

    authors: Chou CY,Anastasio MA,Brankov JG,Wernick MN,Brey EM,Connor DM,Zhong Z

    更新日期:2007-04-07 00:00:00

  • Computational dosimetry in embryos exposed to electromagnetic plane waves over the frequency range of 10 MHz-1.5 GHz.

    abstract::This paper presents calculated specific absorption rate (SAR) dosimetry in 4 and 8 week Japanese pregnant-woman models exposed to plane waves over the frequency range of 10 MHz-1.5 GHz. Two types of 2 mm spatial-resolution pregnant-woman models comprised a woman model, which is similar to the average-sized Japanese ad...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/55/1/N01

    authors: Kawai H,Nagaoka T,Watanabe S,Saito K,Takahashi M,Ito K

    更新日期:2010-01-07 00:00:00

  • Effect of dominant features on neural network performance in the classification of mammographic lesions.

    abstract::Two different classifiers, an artificial neural network (ANN) and a hybrid system (one step rule-based method followed by an artificial neural network) have been investigated to merge computer-extracted features in the task of differentiating between malignant and benign masses. A database consisting of 65 cases (38 m...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/44/10/315

    authors: Huo Z,Giger ML,Metz CE

    更新日期:1999-10-01 00:00:00

  • Concentrations of Fe, Cu and Zn in breast tissue: a synchrotron XRF study.

    abstract::An x-ray fluorescence system with a synchrotron radiation source was used to quantify the levels of iron, copper and zinc in breast tissue specimens. Healthy tissue and breast carcinomas were investigated as an aid to understanding the mechanisms of breast cancer and as a possible complementary diagnostic tool. Eighty...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/47/13/310

    authors: Geraki K,Farquharson MJ,Bradley DA

    更新日期:2002-07-07 00:00:00

  • Survey of numerical electrostimulation models.

    abstract::This paper evaluates results of a survey of electrostimulation models of myelinated nerve. Participants were asked to determine thresholds of excitation for 18 cases involving different characteristics of the neuron, the stimulation waveform, and the electrode arrangement. Responses were received from 7 investigators ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/61/12/4346

    authors: Reilly JP

    更新日期:2016-06-21 00:00:00

  • On the importance of body posture and skin modelling with respect to in situ electric field strengths in magnetic field exposure scenarios.

    abstract::The reference levels and maximum permissible exposure values for magnetic fields that are currently used have been derived from basic restrictions under the assumption of upright standing body models in a standard posture, i.e. with arms laterally down and without contact with metallic objects. Moreover, if anatomical...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/61/12/4412

    authors: Schmid G,Hirtl R

    更新日期:2016-06-21 00:00:00

  • Analytic treatment of resolution precision in electronically collimated SPECT imaging involving multiple-interaction gamma rays.

    abstract::The widely applied single-interaction analytic expression characterizing the energy resolution component of the angular resolution precision for an electronically collimated point source is extended to include multiple-interaction Compton scatter sequences as well as sequences terminated by photoelectric absorption. T...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/43/10/021

    authors: Durkee JW Jr,Antich PP,Tsyganov EN,Constantinescu A,Kulkarni PV,Smith BJ,Arbique GM,Lewis MA,Nguyen T,Raheja A,Thambi G,Parkey RW

    更新日期:1998-10-01 00:00:00

  • Three-dimensional fluorescence tomography of human breast tissues in vivo using a hand-held optical imager.

    abstract::Diffuse optical imaging using non-ionizing radiation is a non-invasive method that shows promise towards breast cancer diagnosis. Hand-held optical imagers show potential for clinical translation of the technology, yet they have not been used towards 3D tomography. Herein, 3D tomography of human breast tissue in vivo ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/58/5/1563

    authors: Erickson SJ,Martinez SL,DeCerce J,Romero A,Caldera L,Godavarty A

    更新日期:2013-03-07 00:00:00

  • A method for determining the diffusion coefficient in Fe(II/III) radiation dosimetry gels using finite elements.

    abstract::Magnetic resonance imaging (MRI) may be used to image three-dimensional dose distributions of ionizing radiation in tissue equivalent gels infused with ferrous sulphate solutions, commonly known as Fricke gels. In this technique, ferrous (Fe2+) ions are oxidized to ferric (Fe3+) ions by free radicals produced by ioniz...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/41/9/013

    authors: Harris PJ,Piercy A,Baldock C

    更新日期:1996-09-01 00:00:00

  • An age-dependent series of eye models for radiation dosimetry.

    abstract::Several studies have been appeared, up to now, that indicate the effect of accurate simulation on dose received by different substructures of the eye, irradiated by external beams of short-range radiation such as electron. Different representations of the eye have consequently been introduced. Their accuracies depend ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab2059

    authors: Vejdani-Noghreiyan A,Ebrahimi-Khankook A

    更新日期:2019-07-02 00:00:00

  • Specific absorbed fractions for a revised series of the UF/NCI pediatric reference phantoms: internal photon sources.

    abstract::Assessment of radiation absorbed dose to internal organs of the body from the intake of radionuclides or, in the medical setting through the injection of radiopharmaceuticals, is generally performed based upon reference biokinetic models or patient imaging data, respectively. Biokinetic models estimate the time course...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/abc708

    authors: Schwarz BC,Godwin WJ,Wayson MB,Dewji SA,Jokisch DW,Lee C,Bolch WE

    更新日期:2020-11-03 00:00:00

  • Directional x-ray dark-field imaging.

    abstract::We introduce a novel x-ray imaging approach that yields information about the local texture of structures smaller than the image pixel resolution inside an object. The approach is based on a recently developed x-ray dark-field imaging technique, using scattering from sub-micron structures in the sample. We show that t...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/55/12/004

    authors: Jensen TH,Bech M,Bunk O,Donath T,David C,Feidenhans'l R,Pfeiffer F

    更新日期:2010-06-21 00:00:00

  • Fluorescence-enhanced three-dimensional lifetime imaging: a phantom study.

    abstract::Near-infrared fluorescence optical imaging has the unique opportunity of differentiating diseased lesions from normal lesions based upon environmentally indicated changes in the lifetime of a fluorescent imaging agent. In this paper, we demonstrate three-dimensional lifetime tomography using the gradient-based penalty...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/52/14/009

    authors: Roy R,Godavarty A,Sevick-Muraca EM

    更新日期:2007-07-21 00:00:00

  • Optimization of multiply acquired magnetic flux density B(z) using ICNE-Multiecho train in MREIT.

    abstract::The aim of magnetic resonance electrical impedance tomography (MREIT) is to visualize the electrical properties, conductivity or current density of an object by injection of current. Recently, the prolonged data acquisition time when using the injected current nonlinear encoding (ICNE) method has been advantageous for...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/55/9/021

    authors: Nam HS,Kwon OI

    更新日期:2010-05-07 00:00:00

  • Posture-specific phantoms representing female and male adults in Monte Carlo-based simulations for radiological protection.

    abstract::Does the posture of a patient have an effect on the organ and tissue absorbed doses caused by x-ray examinations? This study aims to find the answer to this question, based on Monte Carlo (MC) simulations of commonly performed x-ray examinations using adult phantoms modelled to represent humans in standing as well as ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/55/15/014

    authors: Cassola VF,Kramer R,Brayner C,Khoury HJ

    更新日期:2010-08-07 00:00:00

  • Uncertainties in Monte Carlo-based absorbed dose calculations for an experimental benchmark.

    abstract::There is a need to verify the accuracy of general purpose Monte Carlo codes like EGSnrc, which are commonly employed for investigations of dosimetric problems in radiation therapy. A number of experimental benchmarks have been published to compare calculated values of absorbed dose to experimentally determined values....

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/19/7637

    authors: Renner F,Wulff J,Kapsch RP,Zink K

    更新日期:2015-10-07 00:00:00

  • An edge-on charge-transfer design for energy-resolved x-ray detection.

    abstract::As an x-ray beam goes through the human body, it will collect important information via interaction with tissues. Since this interaction is energy-sensitive, the state-of-the-art spectral CT technologies provide higher quality images of biological tissues with x-ray energy information (or spectral information). With e...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/61/11/4183

    authors: Shi Z,Yang H,Cong W,Wang G

    更新日期:2016-06-07 00:00:00

  • Comparison of Monte Carlo and analytical dose computations for intensity modulated proton therapy.

    abstract::To evaluate the effect of approximations in clinical analytical calculations performed by a treatment planning system (TPS) on dosimetric indices in intensity modulated proton therapy. TPS calculated dose distributions were compared with dose distributions as estimated by Monte Carlo (MC) simulations, calculated with ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aaa845

    authors: Yepes P,Adair A,Grosshans D,Mirkovic D,Poenisch F,Titt U,Wang Q,Mohan R

    更新日期:2018-02-09 00:00:00

  • T1 and extracellular volume fraction mapping in cardiac magnetic resonance: estimation of accuracy and precision of a novel algorithm.

    abstract::Magnetic resonance imaging is effective for non-invasive detection of myocardial diseases by extracellular volume fraction (ECV) estimation. A new methodology for T1 and ECV mapping is tested in this work, comparing results with other well-consolidated methods. The associated level of uncertainty for data was also est...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aafcca

    authors: Borrazzo C,Pacilio M,Galea N,Preziosi E,Carnì M,Francone M,Catalano C,Carbone I

    更新日期:2019-02-11 00:00:00

  • An integrated quality assurance phantom for frameless single-isocenter multitarget stereotactic radiosurgery.

    abstract::Brain stereotactic radiosurgery (SRS) treatments require multiple quality assurance (QA) procedures to ensure accurate and precise treatment delivery. As single-isocenter multitarget SRS treatments become more popular, the quantification of off-axis accuracy of the linear accelerator is crucial. In this study, a novel...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab8534

    authors: Capaldi DPI,Skinner LB,Dubrowski P,Yu AS

    更新日期:2020-06-10 00:00:00

  • Ultraviolet phototherapy: review of options for cabin dosimetry and operation.

    abstract::Ultraviolet (UV) treatment dose is determined by the length of time that a patient spends in a phototherapy cabin. The output from UV fluorescent lamps declines with use and a method is needed to compensate for the change in irradiance and to identify and replace any lamps that fail. The decline in lamp output with ag...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/51/2/008

    authors: Amatiello H,Martin CJ

    更新日期:2006-01-21 00:00:00

  • A convolution-subtraction scatter correction method for 3D PET.

    abstract::3D acquisition and reconstruction in positron emission tomography (PET) produce data with improved signal-to-noise ratios compared with conventional 2D slice-oriented methods. However, the sensitivity increase is accompanied by an increase in the number of scattered photons and random coincidences detected. This paper...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/39/3/009

    authors: Bailey DL,Meikle SR

    更新日期:1994-03-01 00:00:00

  • Deformable and durable phantoms with controlled density of scatterers.

    abstract::We have developed deformable and durable optical tissue phantoms with a simple and well-defined microstructure including a novel combination of scatterers and a matrix material. These were developed for speckle and elastography investigations in optical coherence tomography, but should prove useful in many other field...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/53/13/N01

    authors: Bisaillon CE,Lamouche G,Maciejko R,Dufour M,Monchalin JP

    更新日期:2008-07-07 00:00:00

  • A Monte Carlo-based method to estimate radiation dose from spiral CT: from phantom testing to patient-specific models.

    abstract::The purpose of this work is to develop and test a method to estimate the relative and absolute absorbed radiation dose from axial and spiral CT scans using a Monte Carlo approach. Initial testing was done in phantoms and preliminary results were obtained from a standard mathematical anthropomorphic model (MIRD V) and ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/48/16/306

    authors: Jarry G,DeMarco JJ,Beifuss U,Cagnon CH,McNitt-Gray MF

    更新日期:2003-08-21 00:00:00

  • Implementation of pencil kernel and depth penetration algorithms for treatment planning of proton beams.

    abstract::The implementation of two algorithms for calculating dose distributions for radiation therapy treatment planning of intermediate energy proton beams is described. A pencil kernel algorithm and a depth penetration algorithm have been incorporated into a commercial three dimensional treatment planning system (Helax-TMS,...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/45/1/302

    authors: Russell KR,Isacsson U,Saxner M,Ahnesjö A,Montelius A,Grusell E,Dahlgren CV,Lorin S,Glimelius B

    更新日期:2000-01-01 00:00:00

  • Wavelet-packet-based texture analysis for differentiation between benign and malignant liver tumours in ultrasound images.

    abstract::The purpose of this study was to apply a novel method of multiscale echo texture analysis for distinguishing benign (hemangiomas) from malignant (hepatocellular carcinomas (HCCs) and metastases) focal liver lesions in B-mode ultrasound images. In this method, regions of interest (ROIs) extracted from within the lesion...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/48/22/008

    authors: Yoshida H,Casalino DD,Keserci B,Coskun A,Ozturk O,Savranlar A

    更新日期:2003-11-21 00:00:00

  • Simultaneous EEG-fMRI: evaluating the effect of the cabling configuration on the gradient artefact.

    abstract::EEG recordings made in combined EEG-fMRI studies are corrupted by gradient artefacts (GAs) resulting from the interaction of the EEG system with the time-varying magnetic field gradients used in MRI. The dominant contribution to the GA arises from interaction with the leads of the EEG cap and the human head, but artef...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/12/N241

    authors: Chowdhury ME,Mullinger KJ,Bowtell R

    更新日期:2015-06-21 00:00:00

  • Sparse-view x-ray CT reconstruction via total generalized variation regularization.

    abstract::Sparse-view CT reconstruction algorithms via total variation (TV) optimize the data iteratively on the basis of a noise- and artifact-reducing model, resulting in significant radiation dose reduction while maintaining image quality. However, the piecewise constant assumption of TV minimization often leads to the appea...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/59/12/2997

    authors: Niu S,Gao Y,Bian Z,Huang J,Chen W,Yu G,Liang Z,Ma J

    更新日期:2014-06-21 00:00:00

  • Energy response of optically stimulated luminescent dosimeters for non-reference measurement locations in a 6 MV photon beam.

    abstract::Optically stimulated luminescent dosimeters (OSLDs) are becoming increasingly popular for measuring an absorbed dose in clinical radiotherapy. OSLDs have known energy dependence, and this is accounted for by either calibrating the OSLD with a specific nominal energy, or using a standard energy correction factor to acc...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/57/9/2505

    authors: Scarboro SB,Followill DS,Kerns JR,White RA,Kry SF

    更新日期:2012-05-07 00:00:00