Automated cell cycle analysis with fluorescence microscopy and image analysis.

abstract：:An in vivo probe was compared with a gamma camera for the task of detecting radiolabelled tumour models in a water phantom. The probe, which contained a 1 cm diameter NaI(T1) detector, was designed and used by us for surgical staging studies of gynaecological patients. Tumours were spherical sources of different sizes...

journal_title：Physics in medicine and biology

authors： Barber HB,Barrett HH,Woolfenden JM,Myers KJ,Hickernell TS

更新日期：1989-06-01 00:00:00

abstract：:The purpose of this study is to explain the unplanned longitudinal dose modulations that appear in helical tomotherapy (HT) dose distributions in the presence of irregular patient breathing. This explanation is developed by the use of longitudinal (1D) simulations of mock and surrogate data and tested with a fully 4D ...

journal_title：Physics in medicine and biology

authors： Kissick MW,Flynn RT,Westerly DC,Hoban PW,Mo X,Soisson ET,McCall KC,Mackie TR,Jeraj R

更新日期：2008-09-21 00:00:00

abstract：:There is a need to verify the accuracy of general purpose Monte Carlo codes like EGSnrc, which are commonly employed for investigations of dosimetric problems in radiation therapy. A number of experimental benchmarks have been published to compare calculated values of absorbed dose to experimentally determined values....

journal_title：Physics in medicine and biology

authors： Renner F,Wulff J,Kapsch RP,Zink K

更新日期：2015-10-07 00:00:00

abstract：:This work investigated the differences between multileaf collimator (MLC) positioning accuracy determined using either log files or electronic portal imaging devices (EPID) and then assessed the possibility of reducing patient specific quality control (QC) via phantom-less methodologies. In-house software was develope...

journal_title：Physics in medicine and biology

authors： Agnew A,Agnew CE,Grattan MW,Hounsell AR,McGarry CK

更新日期：2014-05-07 00:00:00

abstract：:The values of the replacement correction factors (P(repl), or in the IAEA's notation p(dis)p(cav)) used for cylindrical chambers in high-energy photon beams represent one of the most significant differences between the AAPM and the IAEA dosimetry protocols. In a previous study (Wang L L W and Rogers D W O 2008 Med. Ph...

journal_title：Physics in medicine and biology

authors： Wang LL,Rogers DW

更新日期：2009-03-21 00:00:00

abstract：:A method is described which offers an alternative to conventional Fourier phase/amplitude imaging for analysing representative LV cycles obtained from first-pass cardiac studies. The method involves applying factor analysis to the data and producing functional images of the first two factor loadings after polar transf...

journal_title：Physics in medicine and biology

authors： Houston AS,Elliott AT,Stone DL

更新日期：1982-10-01 00:00:00

abstract：:Successful radiotherapy treatment depends heavily upon the accuracy of patient geometry captured during treatment simulation using computed tomography (CT) scans. Radiotherapy patients are often scanned under free breathing, and respiratory motion can cause severe artifacts in CT scans, including shortening, elongatio...

journal_title：Physics in medicine and biology

authors： Lewis JH,Jiang SB

更新日期：2009-02-07 00:00:00

abstract：:Intensity modulated proton radiotherapy (IMPT) can reduce the dose to critical structures by optimizing the distribution and intensity of individual pencil beams. The IMPT can be delivered by dynamically scanning a pencil beam with variable intensity and energy across the tumor target volume. The lateral penumbra of a...

journal_title：Physics in medicine and biology

authors： Safai S,Bortfeld T,Engelsman M

更新日期：2008-03-21 00:00:00

abstract：:Fast heat extraction is critically important to obtain the maximal benefit of cryogen spray cooling (CSC) during laser therapy of shallow skin lesions, such as port wine stain birthmarks. However, a film of liquid cryogen can build up on the skin surface, impairing heat transfer due to the relatively low thermal condu...

journal_title：Physics in medicine and biology

authors： Majaron B,Svaasand LO,Aguilar G,Nelson JS

更新日期：2002-09-21 00:00:00

abstract：:This work is dedicated to the reduction of reconstruction artefacts due to motion occurring during the acquisition of computerized tomographic projections. This problem has to be solved when imaging moving organs such as the lungs or the heart. The proposed method belongs to the class of motion compensation algorithms...

journal_title：Physics in medicine and biology

authors： Roux S,Desbat L,Koenig A,Grangeat P

更新日期：2004-06-07 00:00:00

abstract：:An important aspect of robotic radiation therapy is active compensation of target motion. Recently, ultrasound has been proposed to obtain real-time volumetric images of abdominal organ motion. One approach to realize flexible probe placement throughout the treatment fraction is based on a robotic arm holding the ultr...

journal_title：Physics in medicine and biology

authors： Schlüter M,Fürweger C,Schlaefer A

更新日期：2019-10-04 00:00:00

abstract：:Modelling of inhaled particle deposition in the lungs potentially offers data relevant to assessing hazards from toxic inhaled particles, to studying mucus clearance or lung permeability by aerosol techniques, and to achieving better utilisation of drugs administered as aerosols. Analysis of published modelling studie...

journal_title：Physics in medicine and biology

authors： Agnew JE,Pavia D,Clarke SW

更新日期：1984-07-01 00:00:00

abstract：:A method was developed to quantify the intensity of tissue staining using a CCD (charge-coupled device) camera. Reflection spectra of NBT-stained (nitro-blue tetrazolium-stained) and unstained myocardium were recorded via fibre optics coupled to a CCD camera, connected to a microcomputer. The calculation of the intens...

journal_title：Physics in medicine and biology

authors： Schröder T,Koch G,Schnabel PA,Hering JP,Bretschneider HJ,Richter J,Hellige G

更新日期：1991-06-01 00:00:00

abstract：:A single experimental apparatus has been designed to allow measurements of stopping cross-sections of materials in liquid and vapour phase, for alpha particles, using an indirect method. The method, in which residual energies for increasing absorber thicknesses are obtained and differentiated, has been used in a numbe...

journal_title：Physics in medicine and biology

authors： Thwaites DI

更新日期：1980-09-01 00:00:00

abstract：:A method is presented to predict beam profiles and outputs for wedged asymmetric fields defined by independent collimator jaws allowing fast generation of beam profiles whilst requiring very little additional data to that already used by most treatment planning systems in generating symmetric field isodoses. Symmetric...

journal_title：Physics in medicine and biology

authors： Millin AE,Smith CW

更新日期：1994-01-01 00:00:00

abstract：:A number of heating sources are available for minimally invasive thermal therapy of tumours. The purpose of this work was to compare, theoretically, the heating characteristics of interstitial microwave, laser and ultrasound sources in three tissue sites: breast, brain and liver. Using a numerical method, the heating ...

journal_title：Physics in medicine and biology

authors： Skinner MG,Iizuka MN,Kolios MC,Sherar MD

更新日期：1998-12-01 00:00:00

abstract：:Patient motion is an important factor affecting the quality of external beam radiotherapy in breast patients. We analyse the motion of a dense set of surface points on breast patients throughout their treatment schedule to assess the magnitude and stability of motion, in particular, with respect to breast volume. We u...

journal_title：Physics in medicine and biology

authors： Price GJ,Sharrock PJ,Marchant TE,Parkhurst JM,Burton D,Jain P,Price P,Moore CJ

更新日期：2009-11-07 00:00:00

abstract：:Assessment of radiation absorbed dose to internal organs of the body from the intake of radionuclides or, in the medical setting through the injection of radiopharmaceuticals, is generally performed based upon reference biokinetic models or patient imaging data, respectively. Biokinetic models estimate the time course...

journal_title：Physics in medicine and biology

authors： Schwarz BC,Godwin WJ,Wayson MB,Dewji SA,Jokisch DW,Lee C,Bolch WE

更新日期：2020-11-03 00:00:00

abstract：:Effects of different scatter compensation methods incorporated in fully 3D iterative reconstruction are investigated. The methods are: (i) the inclusion of an 'ideal scatter estimate' (ISE); (ii) like (i) but with a noiseless scatter estimate (ISE-NF); (iii) incorporation of scatter in the point spread function during...

journal_title：Physics in medicine and biology

authors： Beekman FJ,Kamphuis C,Frey EC

更新日期：1997-08-01 00:00:00

abstract：:A non-contact approach for diffuse optical tomography (DOT) has been developed for on-demand image updates using surgical navigation technology. A stereoscopic optical tracker provides real-time localization of reflective spheres mounted to a laser diode and near-infrared camera. Standard camera calibration is combine...

journal_title：Physics in medicine and biology

authors： Daly MJ,Wilson BC,Irish JC,Jaffray DA

更新日期：2019-07-05 00:00:00

abstract：:It was observed that the radiation output of x-ray tubes falls off exponentially during an exposure with a time constant of about 120 ms. The equilibrium value is approximately 15% lower than that at the beginning of the exposure. The clinically noticeable consequences are discrepancies in x-ray generator calibration,...

journal_title：Physics in medicine and biology

authors： Brezovich IA,Barnes GT

更新日期：1980-03-01 00:00:00

abstract：:Due to high levels of noise in pixel-wise time-activity curves, the indirect method that generates kinetic parametric images from dynamic positron emission tomography (PET) images often results in poor parametric image quality. We have demonstrated that the quality of parametric images can be improved by denoising dyn...

journal_title：Physics in medicine and biology

authors： Huang HM

更新日期：2020-11-17 00:00:00

abstract：:Radiation dose distributions have been calculated for 188Re and 32P activity on a coronary artery stent. The doses have been calculated both as a function of position along the stent and of depth into the artery wall. Comparisons of the dose from identical activities of 188Re and 32P on the stent show that the major d...

journal_title：Physics in medicine and biology

authors： Fox RA,Henson PW

更新日期：2000-12-01 00:00:00

abstract：:The classical Sievert integral method is a valuable tool for dose rate calculations around brachytherapy sources, combining simplicity with reasonable computational times. However, its accuracy in predicting dose rate anisotropy around 192Ir brachytherapy sources has been repeatedly put into question. In this work, we...

journal_title：Physics in medicine and biology

authors： Karaiskos P,Angelopoulos A,Baras P,Rozaki-Mavrouli H,Sandilos P,Vlachos L,Sakelliou L

更新日期：2000-02-01 00:00:00

abstract：:Analytic solutions to the time-dependent multiregion bioheat equation are evaluated numerically for cartesian and spherical models. Principle and alternate branch contributions to the solutions are examined. The calculations include a parametric investigation and analyses of temperature behaviour in idealised upper th...

journal_title：Physics in medicine and biology

authors： Durkee JW Jr,Antich PP,Lee CE

更新日期：1990-07-01 00:00:00

abstract：:A classical trajectory model has been used to predict total cross sections of single and double ionizing processes (including capture processes) for several ion-biological molecule collisional systems in the intermediate and high energy range. In this work, the systems studied are water, adenine or cytosine targets io...

journal_title：Physics in medicine and biology

authors： Abbas I,Champion C,Zarour B,Lasri B,Hanssen J

更新日期：2008-02-21 00:00:00

abstract：:The medical imaging and therapeutic technologies that are based on the use of radiation are reviewed briefly, with special emphasis on the recent developments of synchrotron radiation (SR) methods. New results have been achieved in all of these areas since the last comprehensive reviews were written in this field. Thi...

journal_title：Physics in medicine and biology

authors： Suortti P,Thomlinson W

更新日期：2003-07-07 00:00:00

abstract：:Recent studies of the minute morphology of the skin by optical coherence tomography revealed that the sweat ducts in human skin are helically shaped tubes, filled with a conductive aqueous solution. This, together with the fact that the dielectric permittivity of the dermis is higher than that of the epidermis, brings...

journal_title：Physics in medicine and biology

authors： Feldman Y,Puzenko A,Ben Ishai P,Caduff A,Davidovich I,Sakran F,Agranat AJ

更新日期：2009-06-07 00:00:00

abstract：:A reader study was conducted to tune the parameters of an observer model used to predict the detectability index (dʹ ) of test objects as a task-based quality control (QC) metric for digital mammography. A simple test phantom was imaged to measure the model parameters, namely, noise power spectrum,modulation transfer ...

journal_title：Physics in medicine and biology

authors： Bloomquist AK,Mainprize JG,Mawdsley GE,Yaffe MJ

更新日期：2014-11-07 00:00:00

abstract：:Most existing spatiotemporal multi-dipole approaches for MEG/EEG source localization assume that the dipoles are active for the full time range being analysed. If the actual time range of activity of sources is significantly shorter than the time range being analysed, the detectability, localization and time-course de...

journal_title：Physics in medicine and biology

authors： Jun SC,George JS,Plis SM,Ranken DM,Schmidt DM,Wood CC

更新日期：2006-05-21 00:00:00