Abstract:
:Analytic solutions to the time-dependent multiregion bioheat equation are evaluated numerically for cartesian and spherical models. Principle and alternate branch contributions to the solutions are examined. The calculations include a parametric investigation and analyses of temperature behaviour in idealised upper thigh and tumour models.
journal_name
Phys Med Bioljournal_title
Physics in medicine and biologyauthors
Durkee JW Jr,Antich PP,Lee CEdoi
10.1088/0031-9155/35/7/005subject
Has Abstractpub_date
1990-07-01 00:00:00pages
869-89issue
7eissn
0031-9155issn
1361-6560journal_volume
35pub_type
杂志文章abstract::A modified sector-integration method is presented that can predict the output factors of irregular shaped electron fields even in the case of extended source to surface distance (SSD). The model takes as input measured output factors for circular inserts of various radii. These circular fields were measured at SSDs of...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/45/11/318
更新日期:2000-11-01 00:00:00
abstract::We report the first experimental soft-tissue phase-contrast tomography results using a conventional x-ray tube source, with a millimeter-sized focal spot. The setup is based on a Talbot-Lau grating interferometer operated at a mean energy of 28 keV. We present three-dimensional ex vivo images of a chicken heart sample...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/54/9/010
更新日期:2009-05-07 00:00:00
abstract::Tumor motion is a particular concern for a complex treatment modality such as helical tomotherapy, where couch position, gantry rotation and MLC leaf opening all change with time. In the present study, we have investigated the impact of tumor motion for helical tomotherapy, which could result in three distinct motion-...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/54/19/004
更新日期:2009-10-07 00:00:00
abstract::Measuring spin-spin relaxation times (T2) by quantitative MR imaging represents a potentially efficient tool to evaluate the physicochemical properties of various media. However, noise in MR images is responsible for uncertainties in the determination of T2 relaxation times, which limits the accuracy of parametric tis...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/51/11/011
更新日期:2006-06-07 00:00:00
abstract::By means of a transonic gas jet, gene guns ballistically deliver microparticle formulations of drugs and vaccines to the outer layers of the skin or mucosal tissue to induce unique physiological responses for the treatment of a range of conditions. Reported high-speed imaging experiments show that the mucosa deforms s...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/50/19/010
更新日期:2005-10-07 00:00:00
abstract::The cerebral arteries are difficult to reproduce from first principles, featuring interwoven territories, and intricate layers of grey and white matter with differing metabolic demand. The aim of this study was to identify the ideal configuration of arteries required to sustain an entire brain hemisphere based on mini...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/1361-6560/ab2479
更新日期:2019-06-21 00:00:00
abstract::Monte Carlo calculations of the energy response of LiF dosemeters have been carried out to help resolve the discrepancy between the measurements of Holt, Edelstein and Clark (1975) and those of Paliwal and Almond (1975) and others. It is concluded that the assumptions used by Holt et al. are largely responsible. They ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/22/5/003
更新日期:1977-09-01 00:00:00
abstract::Several methods of flip angle mapping for magnetic resonance imaging have been proposed. We evaluated the accuracy of five methods of flip angle measurement in the presence of measurement noise. Our analysis was performed in a closed form by propagation of probability density functions (PDFs). The flip angle mapping m...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/55/20/008
更新日期:2010-10-21 00:00:00
abstract::This paper presents two methods for absorbed dose determination with ionization chambers at short distance from 60Co and 192Ir brachytherapy sources. The methods are modifications of the Bragg-Gray and large cavity principles given in the IAEA code of practice for high- and medium-energy photon beams. A non-uniformity...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/43/11/002
更新日期:1998-11-01 00:00:00
abstract::Medulloblastoma treatment involves irradiation of the entire central nervous system, i.e. craniospinal irradiation (CSI). This is associated with the significant exposure of large volumes of healthy tissue and there is growing concern regarding treatment-associated side effects. The current study compares out-of-field...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/1361-6560/aa6c9e
更新日期:2017-07-07 00:00:00
abstract::Microbeam radiation therapy (MRT) is a treatment approach in radiation therapy where the treatment field is spatially fractionated into arrays of a few tens of micrometre wide planar beams of unusually high peak doses separated by low dose regions of several hundred micrometre width. In preclinical studies, this treat...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/1361-6560/aa8d63
更新日期:2017-10-19 00:00:00
abstract::The dosimetric measurement and modeling of small radiation treatment fields (<2 × 2 cm2) are difficult to perform and prone to error. Measurements of small fields are often adversely influenced by the properties of the detectors used to make them. The dosimetric properties of small fields have been difficult to accura...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/56/12/015
更新日期:2011-06-21 00:00:00
abstract::A mathematical transcription of the intrinsic circuit of the CA1 region of the rat dorsal hippocampus was made and the model parameters adjusted according to experimental data from intracellular recordings and single channel kinetics. This model was able to simulate well the profile of the field potentials recorded ex...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/43/9/014
更新日期:1998-09-01 00:00:00
abstract::By the end of 2002, 33 398 patients worldwide had been treated with proton radiotherapy, 10 829 for eye diseases. The dose prediction algorithms used today for ocular proton therapy treatment planning rely on parameterizations of measured proton dose distributions, i.e., broad-beam and pencil-beam techniques, whose pr...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/50/22/002
更新日期:2005-11-21 00:00:00
abstract::The probability of a photon (x-ray, gamma-ray, bremsstrahlung, etc) of a given energy E undergoing absorption or scattering when traversing a layer of material Z can be expressed quantitatively in terms of a linear attenuation coefficient mu (cm(-1)). Since mu is dependent on the material's density, rho (g cm(-3)), wh...
journal_title:Physics in medicine and biology
pub_type: 杂志文章,评审
doi:10.1088/0031-9155/44/1/001
更新日期:1999-01-01 00:00:00
abstract::Heating induced near deep brain stimulation (DBS) lead electrodes during magnetic resonance imaging with a 3 T transceive head coil was measured, modeled, and imaged in three cadaveric porcine heads (mean body weight = 85.47 ± 3.19 kg, mean head weight = 5.78 ± 0.32 kg). The effect of the placement of the extra-crania...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/57/17/5651
更新日期:2012-09-07 00:00:00
abstract::Advanced radiotherapeutical techniques like intensity-modulated radiation therapy (IMRT) are based on an accurate knowledge of the location of the radiation target. An accurate dose delivery, therefore, requires a method to account for the inter- and intrafractional target motion and the target deformation occurring d...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/52/22/N01
更新日期:2007-11-21 00:00:00
abstract::Reference dosimetry of photon fields is a well-established subject and currently available protocols (such as the IAEA TRS-398 and AAPM TG-51) provide methods for converting the ionization chamber (IC) reading into dose to water, provided reference conditions of charged particle equilibrium (CPE) are fulfilled. But th...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/51/6/011
更新日期:2006-03-21 00:00:00
abstract::Positron emission tomography (PET) has become an important modality in medical and molecular imaging. However, in most PET applications, the resolution is still mainly limited by the physical crystal sizes or the detector's intrinsic spatial resolution. To achieve images with better spatial resolution in a central reg...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/60/2/647
更新日期:2015-01-21 00:00:00
abstract::A new multiplicative correction factor for tissue heterogeneities based on an exact expression for homogeneous non-unit-density media is proposed. O'Connor's density scaling theorem is invoked to evaluate the medium-specific tissue-maximum ratios used in the exact formulation. Monte Carlo calculations were performed a...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/31/10/005
更新日期:1986-10-01 00:00:00
abstract::In recent years, there has been an increase in the popularity of light-emitting diode (LED)-based, battery-powered transilluminators (BPTs) for facilitating transdermal vascular access in adults and neonates. BPTs are believed to have lower potential for inducing skin burns than prior devices based on high-power broad...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/54/22/008
更新日期:2009-11-21 00:00:00
abstract::The sulphuric acid used for the preparation of the Fricke dosimeter solution may contain trace impurities that can affect the yield of ferric ions. Two methods, pre-irradiation or oxidation with hydrogen peroxide, have been proposed to reduce the influence of these impurities. Fricke users sometimes omit this treatmen...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/45/9/403
更新日期:2000-09-01 00:00:00
abstract::For proton therapy, an accurate conversion of CT HU to relative stopping power (RSP) is essential. Validation of the conversion based on real tissue samples is more direct than the current practice solely based on tissue substitutes and can potentially address variations over the population. Based on a novel dose exti...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/1361-6560/aa782c
更新日期:2017-06-23 00:00:00
abstract::Coronary computed tomography angiography (cCTA) is a commonly used imaging modality for the evaluation of coronary artery disease. cCTA is generally reconstructed in multiple cardiac phases because different coronary arteries may be better visualized in some phases than in others due to the periodic cardiac motion. We...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/59/16/4661
更新日期:2014-08-21 00:00:00
abstract::The purpose of this work is to develop and test a method to estimate the relative and absolute absorbed radiation dose from axial and spiral CT scans using a Monte Carlo approach. Initial testing was done in phantoms and preliminary results were obtained from a standard mathematical anthropomorphic model (MIRD V) and ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/48/16/306
更新日期:2003-08-21 00:00:00
abstract::It is a challenging problem to resolve and identify drug (or non-specific fluorophore) distribution throughout the whole body of small animals in vivo. In this article, an algorithm of unmixing multispectral fluorescence tomography (MFT) images based on independent component analysis (ICA) is proposed to solve this pr...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/59/17/5025
更新日期:2014-09-07 00:00:00
abstract::A theoretical analysis is presented of the biologically effective dose of the solar long wave ultraviolet radiation (UVA) received by patients who are being treated for psoriasis by oral psoralen photochemotherapy. It is shown that patients treated during the summer months in the UK may well receive a UV dose which is...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/26/6/011
更新日期:1981-11-01 00:00:00
abstract::This work aims to develop, implement and validate a Monte Carlo (MC)-based independent dose calculation (IDC) framework to perform patient-specific quality assurance (QA) for multi-leaf collimator (MLC)-based CyberKnife® (Accuray Inc., Sunnyvale, CA) treatment plans. The IDC framework uses an XML-format treatment plan...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/1361-6560/aa97f8
更新日期:2017-12-19 00:00:00
abstract::The application of thermal modelling for hyperthermia and thermal ablation is severely hampered by lack of information about perfusion and vasculature. However, recently, with the advent of sophisticated angiography and dynamic contrast enhanced (DCE) imaging techniques, it has become possible to image small vessels a...
journal_title:Physics in medicine and biology
pub_type: 临床试验,杂志文章
doi:10.1088/0031-9155/51/4/004
更新日期:2006-02-21 00:00:00
abstract::Measurement of the dielectric properties of ocular tissues up to 110 GHz was performed by the coaxial probe method. A coaxial sensor was fabricated to allow the measurement of small amounts of biological tissues. Four-standard calibration was applied in the dielectric property measurement to obtain more accurate data ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/60/16/6273
更新日期:2015-08-21 00:00:00