Mathematical model of the CA1 region of the rat hippocampus.

abstract：:A recently described, computer aided method of attenuation analysis has been applied to free-air chamber measurements of the attenuation by up to 30mm A1 of the exposure rate of a narrow beam of X-radiation excited at a thick W target in a Be window tube by constant potentials of 60, 80, 100, 120 and 140 kV. It has ...

journal_title：Physics in medicine and biology

authors： Soole BW

更新日期：1977-03-01 00:00:00

abstract：:The standard mammogram form (SMF) representation of an x-ray mammogram is a standardized, quantitative representation of the breast from which the volume of non-fat tissue and breast density can be easily estimated, both of which are of significant interest in determining breast cancer risk. Previous theoretical analy...

journal_title：Physics in medicine and biology

authors： Highnam R,Pan X,Warren R,Jeffreys M,Davey Smith G,Brady M

更新日期：2006-06-07 00:00:00

abstract：:Output normalized dose profiles for asymmetric open photon fields has been calculated using a commercial treatment planning system (TPS) based on a dose-to-energy-fluence concept. The model does not require any additional measurements for off-axis fields. Calculations are compared with measurements for quadratic field...

journal_title：Physics in medicine and biology

authors： Hurkmans C,Knöös T,Nilsson P

更新日期：1996-08-01 00:00:00

abstract：:ICRP Publication 116 on 'Conversion coefficients for radiological protection quantities for external radiation exposures', provides fluence-to-dose conversion coefficients for organ-absorbed doses and effective dose for various types of external exposures (ICRP 2010 ICRP Publication 116). The publication supersedes th...

journal_title：Physics in medicine and biology

authors： Petoussi-Henss N,Bolch WE,Eckerman KF,Endo A,Hertel N,Hunt J,Menzel HG,Pelliccioni M,Schlattl H,Zankl M

更新日期：2014-09-21 00:00:00

abstract：:We study threshold-driven optimization methodology for automatically generating a treatment plan that is motivated by a reference DVH for IMRT treatment planning. We present a framework for threshold-driven optimization for reference-based auto-planning (TORA). Commonly used voxel-based quadratic penalties have two co...

journal_title：Physics in medicine and biology

authors： Long T,Chen M,Jiang S,Lu W

更新日期：2018-02-08 00:00:00

abstract：:The metabolic content of urine from NIH III nude mice (n = 22) was analysed before and after inoculation with human glioblastoma multiforme (GBM) cancer cells. An age- and gender-matched control population (n = 14) was also studied to identify non-tumour-related changes. Urine samples were collected daily for 6 weeks,...

journal_title：Physics in medicine and biology

authors： Moroz J,Turner J,Slupsky C,Fallone G,Syme A

更新日期：2011-02-07 00:00:00

abstract：:The accurate determination of mean ionization potential (I m) has the potential to reduce range uncertainty based margins and therefore allow for more focal treatments in proton radiotherapy. Many methods have been proposed to reduce uncertainty in I m and stopping power ratios (SPR), each with varying degrees of accu...

journal_title：Physics in medicine and biology

authors： Sudhyadhom A

更新日期：2017-10-27 00:00:00

abstract：:Recently, there has been a resurgence of interest in arc-based IMRT, through the use of 'conventional' multileaf collimator (MLC) systems that can treat large tumor volumes in a single, or very few pass(es) of the gantry. Here we present a novel 'burst mode' modulated arc delivery approach, wherein 2000 monitor units ...

journal_title：Physics in medicine and biology

authors： Salter BJ,Sarkar V,Wang B,Shukla H,Szegedi M,Rassiah-Szegedi P

更新日期：2011-04-07 00:00:00

abstract：:Cell experiments have shown the proton relative biological effectiveness (RBE) to vary with dose and linear energy transfer (LET), which has led to development of variable RBE models. The RBE is normally estimated from two independent functions, the RBEmax and RBEmin, describing the extreme RBE at low and high doses. ...

journal_title：Physics in medicine and biology

authors： Rørvik E,Thörnqvist S,Ytre-Hauge KS

更新日期：2019-09-23 00:00:00

abstract：:In carbon ion therapy treatment planning, the relative biological effectiveness (RBE) is accounted for by optimization of the RBE-weighted dose (biological dose). The RBE calculation methods currently applied clinically in carbon ion therapy are derived from the microdosimetric kinetic model (MKM) in Japan and the loc...

journal_title：Physics in medicine and biology

authors： Dahle TJ,Magro G,Ytre-Hauge KS,Stokkevåg CH,Choi K,Mairani A

更新日期：2018-11-12 00:00:00

abstract：:Positron emission tomography (PET) has become an important modality in medical and molecular imaging. However, in most PET applications, the resolution is still mainly limited by the physical crystal sizes or the detector's intrinsic spatial resolution. To achieve images with better spatial resolution in a central reg...

journal_title：Physics in medicine and biology

authors： Li Y,Matej S,Karp JS,Metzler SD

更新日期：2015-01-21 00:00:00

abstract：:A hybrid differential and spatially resolved spectroscopy (SRS) technique has been developed to measure absolute absorption coefficient (mu(a)), reduced scattering coefficient (mu'(s)) and cerebral blood volume (CBV) in the adult human head. A spectrometer with both differential and SRS capabilities has been used to c...

journal_title：Physics in medicine and biology

authors： Leung TS,Tachtsidis I,Smith M,Delpy DT,Elwell CE

更新日期：2006-02-07 00:00:00

abstract：:Avoiding toxicities in radiotherapy requires the knowledge of tolerable organ doses. For new, experimental fractionation schemes (e.g. hypofractionation) these are typically derived from traditional schedules using the biologically effective dose (BED) model. In this report we investigate the difficulties of establish...

journal_title：Physics in medicine and biology

authors： Perkó Z,Bortfeld T,Hong T,Wolfgang J,Unkelbach J

更新日期：2018-02-05 00:00:00

abstract：:Amorphous silicon electronic portal imaging devices (EPIDs) are used to perform routine quality control (QC) checks on the multileaf collimators (MLCs) at this centre. Presently, these checks are performed at gantry angle 0 degrees and are considered to be valid for all other angles. Since therapeutic procedures regul...

journal_title：Physics in medicine and biology

authors： Clarke MF,Budgell GJ

更新日期：2008-01-21 00:00:00

abstract：:Results from dielectric studies on the freshwater fish Cyprinus carpio exposed to a sublethal concentration of sodium alkyl benzene sulphonate were compared with those from untreated control fish; recovery from the test solution was also checked. The influence of the anionic detergent on the intracellular matter of fi...

journal_title：Physics in medicine and biology

authors： Bielinska I,Terlecki J

更新日期：1984-05-01 00:00:00

abstract：:Time-of-flight (TOF) positron emission tomography (PET) technology has recently regained popularity in clinical PET studies for improving image quality and lesion detectability. Using TOF information, the spatial location of annihilation events is confined to a number of image voxels along each line of response, there...

journal_title：Physics in medicine and biology

authors： Mehranian A,Kotasidis F,Zaidi H

更新日期：2016-02-07 00:00:00

abstract：:Kilovoltage intratreatment monitoring (KIM) is a novel real-time localization modality where the tumor position is continuously measured during intensity modulated radiation therapy (IMRT) or intensity modulated arc therapy (IMAT) by a kilovoltage (kV) x-ray imager. Adding kV imaging during therapy adds radiation dose...

journal_title：Physics in medicine and biology

authors： Ng JA,Booth J,Poulsen P,Kuncic Z,Keall PJ

更新日期：2013-09-07 00:00:00

abstract：:Brain stereotactic radiosurgery (SRS) treatments require multiple quality assurance (QA) procedures to ensure accurate and precise treatment delivery. As single-isocenter multitarget SRS treatments become more popular, the quantification of off-axis accuracy of the linear accelerator is crucial. In this study, a novel...

journal_title：Physics in medicine and biology

authors： Capaldi DPI,Skinner LB,Dubrowski P,Yu AS

更新日期：2020-06-10 00:00:00

abstract：:Large blood vessels can produce steep temperature gradients in heated tissues leading to inadequate tissue temperatures during hyperthermia. This paper utilizes a finite difference scheme to solve the basic equations of heat transfer and fluid flow to model blood vessel cooling. Unlike previous formulations, heat tran...

journal_title：Physics in medicine and biology

authors： Kolios MC,Sherar MD,Hunt JW

更新日期：1995-04-01 00:00:00

abstract：:Most commonly in radiation therapy, treatments are delivered in a co-planar geometry. Numerous advantages have been reported of adding non-coplanar beams to the treatment plan. The aim of this study was to compare current state-of-the-art VMAT and CyberKnife treatment plans to that of a novel linac design developed at...

journal_title：Physics in medicine and biology

authors： Schüler E,Wang L,Loo BW,Maxim PG

更新日期：2019-06-20 00:00:00

abstract：:The use of liquid ionization chambers in radiotherapy has grown during the past few years. While for air ionization chambers the k(TP) correction for air mass density due to pressure and temperature variations is well known, less work has been done on the case of liquid ionization chambers, where there is still the ne...

journal_title：Physics in medicine and biology

authors： Gómez F,González-Castaño D,Díaz-Botana P,Pardo-Montero J

更新日期：2014-06-07 00:00:00

abstract：:Accurate scatter correction is required to produce high-quality reconstructions of x-ray cone-beam computed tomography (CBCT) scans. This paper describes new scatter kernel superposition (SKS) algorithms for deconvolving scatter from projection data. The algorithms are designed to improve upon the conventional approac...

journal_title：Physics in medicine and biology

authors： Sun M,Star-Lack JM

更新日期：2010-11-21 00:00:00

abstract：:Irreversible electroporation (IRE) is a minimally invasive tumor therapy using pulsed electric field with high intensity while the important tissues such as blood vessel, bile duct, and nerve are preserved. In addition to ablation area, reversible electroporation (RE) region is also generated using needle electrodes f...

journal_title：Physics in medicine and biology

authors： Lv Y,Tang X,Peng W,Cheng X,Chen S,Yao C

更新日期：2020-10-14 00:00:00

abstract：:As a new method, x-ray diffraction enhanced imaging (DEI) has extremely high sensitivity for weakly absorbing low-Z samples in medical and biological fields. Conventional performance parameters, such as spatial resolution and low-contrast resolution, are not enough to describe the characteristics of a DEI system. This...

journal_title：Physics in medicine and biology

authors： Huang ZF,Kang KJ,Li Z

更新日期：2006-06-21 00:00:00

abstract：:At certain frequencies, when the human head becomes a resonant structure, the power absorbed by the head and neck, when the body is exposed to a vertically polarized plane wave propagating from front to back, becomes significantly larger than would ordinarily be expected from its shadow cross section. This has possibl...

journal_title：Physics in medicine and biology

authors： Tinniswood AD,Furse CM,Gandhi OP

更新日期：1998-08-01 00:00:00

abstract：:Micro-CT is widely used in preclinical studies, generating substantial interest in extending its capabilities in functional imaging applications such as blood perfusion and cardiac function. However, imaging cardiac structure and function in mice is challenging due to their small size and rapid heart rate. To overcome...

journal_title：Physics in medicine and biology

authors： Holbrook M,Clark DP,Badea CT

更新日期：2018-01-09 00:00:00

abstract：:The analysis of (x-ray) mammograms remains qualitative, relying on the judgement of clinicians. We present a novel method to compute a quantitative, normalized measure of tissue radiodensity traversed by the primary beam incident on each pixel of a mammogram, a measure we term the standard attenuation rate (SAR). SAR ...

journal_title：Physics in medicine and biology

authors： Tromans CE,Cocker MR,Brady SM

更新日期：2012-10-21 00:00:00

abstract：:Clinical diffusion MRI (dMRI) is sensitive to micrometer scale spin displacements, but the image resolution is  ∼mm, so the biophysical interpretation of the signal relies on establishing appropriate subvoxel tissue models. A class of two-compartment exchange models originally proposed by Kärger have been used success...

journal_title：Physics in medicine and biology

authors： Naughton NM,Georgiadis JG

更新日期：2019-08-01 00:00:00

abstract：:Arc-therapy is a dose delivery technique regularly applied in photon radiation therapy, and is currently subject of great interest for proton therapy as well. In this technique, proton beams are aimed at a tumor from different continuous ranges of incident directions (so called "arcs"). This technique can potentially ...

journal_title：Physics in medicine and biology

authors： Nesteruk KP,Bolsi A,Lomax AJ,Meer D,van de Water S,Schippers JM

更新日期：2021-01-26 00:00:00

abstract：:This paper describes an accurate and time-efficient method for the determination of total body potassium via a combination of measurements in the Birmingham whole body counter and the use of the Monte Carlo n-particle (MCNP) simulation code. In developing this method, MCNP has also been used to derive values for some ...

journal_title：Physics in medicine and biology

authors： O'Hehir S,Green S,Beddoe AH

更新日期：2006-09-07 00:00:00