Scatter compensation methods in 3D iterative SPECT reconstruction: a simulation study.

Abstract:

:Effects of different scatter compensation methods incorporated in fully 3D iterative reconstruction are investigated. The methods are: (i) the inclusion of an 'ideal scatter estimate' (ISE); (ii) like (i) but with a noiseless scatter estimate (ISE-NF); (iii) incorporation of scatter in the point spread function during iterative reconstruction ('ideal scatter model', ISM); (iv) no scatter compensation (NSC); (v) ideal scatter rejection (ISR), as can be approximated by using a camera with a perfect energy resolution. The iterative method used was an ordered subset expectation maximization (OS-EM) algorithm. A cylinder containing small cold spheres was used to calculate contrast-to-noise curves. For a brain study, global errors between reconstruction and 'true' distributions were calculated. Results show that ISR is superior to all other methods. In all cases considered, ISM is superior to ISE and performs approximately as well as (brain study) or better than (cylinder data) ISE-NF. Both ISM and ISE improve contrast-to-noise curves and reduce global errors, compared with NSC. In the case of ISE, blurring of the scatter estimate with a Gaussian kernel results in slightly reduced errors in brain studies, especially at low count levels. The optimal Gaussian kernel size is strongly dependent on the noise level.

journal_name

Phys Med Biol

authors

Beekman FJ,Kamphuis C,Frey EC

doi

10.1088/0031-9155/42/8/011

subject

Has Abstract

pub_date

1997-08-01 00:00:00

pages

1619-32

issue

8

eissn

0031-9155

issn

1361-6560

journal_volume

42

pub_type

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