A theoretical comparison of energy sources--microwave, ultrasound and laser--for interstitial thermal therapy.

abstract：:The (83)Kr magnetic resonance (MR) relaxation time T(1) of krypton gas in contact with model surfaces was previously found to be highly sensitive to surface composition, surface-to-volume ratio, and surface temperature. The work presented here explored aspects of pulmonary (83)Kr T(1) relaxation measurements in excise...

journal_title：Physics in medicine and biology

authors： Stupic KF,Elkins ND,Pavlovskaya GE,Repine JE,Meersmann T

更新日期：2011-07-07 00:00:00

abstract：:Determining a multidimensional velocity field within microscale opaque fluid flows is needed in areas such as microfluidic devices, biofluid mechanics and hemodynamics research in animal studies. The ultrasonic particle image velocimetry (EchoPIV) technique is appropriate for measuring opaque flows by taking advantage...

journal_title：Physics in medicine and biology

authors： Qian M,Niu L,Wang Y,Jiang B,Jin Q,Jiang C,Zheng H

更新日期：2010-10-21 00:00:00

abstract：:The exponential edge-gradient effect must arise in any x-ray transmission CT scanner whenever long sharp edges of high contrast are encountered. The effect is non-linear and is due to the interaction of the exponential law of x-ray attenuation and the finite width of the scanning beam in the x-y plane. The error induc...

journal_title：Physics in medicine and biology

authors： Joseph PM,Spital RD

更新日期：1981-05-01 00:00:00

abstract：:The purpose of this study was to apply a novel method of multiscale echo texture analysis for distinguishing benign (hemangiomas) from malignant (hepatocellular carcinomas (HCCs) and metastases) focal liver lesions in B-mode ultrasound images. In this method, regions of interest (ROIs) extracted from within the lesion...

journal_title：Physics in medicine and biology

authors： Yoshida H,Casalino DD,Keserci B,Coskun A,Ozturk O,Savranlar A

更新日期：2003-11-21 00:00:00

abstract：:In this study, the safety compliance for nonuniform field exposures is discussed using coupling factor concepts. The coupling factor, which is defined in the International Electrotechnical Commission 62311 standard, is extended to consider the effects of harmonics and also to apply to the specific absorption rate (for...

journal_title：Physics in medicine and biology

authors： Sunohara T,Hirata A,Laakso I,De Santis V,Onishi T

更新日期：2015-10-21 00:00:00

abstract：:An ultrahigh-resolution full-field optical coherence tomography (OCT) system has been developed for cellular-level imaging of biological media. The system is based on a Linnik interference microscope illuminated with a tungsten halogen lamp, associated with a high-resolution CCD camera. En face tomographic images are ...

journal_title：Physics in medicine and biology

authors： Dubois A,Moneron G,Grieve K,Boccara AC

更新日期：2004-04-07 00:00:00

abstract：:Contrast enhanced ultrasound (CEUS) and dynamic contrast enhanced ultrasound (DCE-US) can be used to provide information about the vasculature aiding diagnosis and monitoring of a number of pathologies including cancer. In the development of a CEUS imaging system, there are many choices to be made, such as whether to ...

journal_title：Physics in medicine and biology

authors： Moghimirad E,Bamber J,Harris E

更新日期：2019-04-23 00:00:00

abstract：:Cell experiments have shown the proton relative biological effectiveness (RBE) to vary with dose and linear energy transfer (LET), which has led to development of variable RBE models. The RBE is normally estimated from two independent functions, the RBEmax and RBEmin, describing the extreme RBE at low and high doses. ...

journal_title：Physics in medicine and biology

authors： Rørvik E,Thörnqvist S,Ytre-Hauge KS

更新日期：2019-09-23 00:00:00

abstract：:We study threshold-driven optimization methodology for automatically generating a treatment plan that is motivated by a reference DVH for IMRT treatment planning. We present a framework for threshold-driven optimization for reference-based auto-planning (TORA). Commonly used voxel-based quadratic penalties have two co...

journal_title：Physics in medicine and biology

authors： Long T,Chen M,Jiang S,Lu W

更新日期：2018-02-08 00:00:00

abstract：:We present a new method for automated characterization of atherosclerotic plaque composition in ex vivo MRI. It uses MRI intensities as well as four other types of features: smoothed, gradient magnitude and Laplacian images at several scales, and the distances to the lumen and outer vessel wall. The ground truth for f...

journal_title：Physics in medicine and biology

authors： van Engelen A,Niessen WJ,Klein S,Groen HC,Verhagen HJ,Wentzel JJ,van der Lugt A,de Bruijne M

更新日期：2012-01-07 00:00:00

abstract：:Recently, the initial 2D physical characterization of a small-diameter positron emission tomograph, designed specifically for scanning of small laboratory animals, was reported. The physical characteristics of the tomograph operating in 3D mode have now been measured and compared to those obtained in 2D mode. In 3D, t...

journal_title：Physics in medicine and biology

authors： Bloomfield PM,Myers R,Hume SP,Spinks TJ,Lammertsma AA,Jones T

更新日期：1997-02-01 00:00:00

abstract：:Dynamic contrast enhanced MRI (DCE-MRI) and pharmacokinetic models have been used to measure tumour permeability (K(trans)) and leakage volume (ve) in numerous studies. The construction of pharmacokinetic models describing such tissue properties relies on defining the blood plasma concentration of contrast agent with ...

journal_title：Physics in medicine and biology

authors： Ahearn TS,Staff RT,Redpath TW,Semple SI

更新日期：2004-05-21 00:00:00

abstract：:Measurement of the dielectric properties of ocular tissues up to 110 GHz was performed by the coaxial probe method. A coaxial sensor was fabricated to allow the measurement of small amounts of biological tissues. Four-standard calibration was applied in the dielectric property measurement to obtain more accurate data ...

journal_title：Physics in medicine and biology

authors： Sasaki K,Isimura Y,Fujii K,Wake K,Watanabe S,Kojima M,Suga R,Hashimoto O

更新日期：2015-08-21 00:00:00

abstract：:We have measured the bulk optical properties of healthy female breast tissues in vivo in the parallel plate, transmission geometry. Fifty-two volunteers were measured. Blood volume and blood oxygen saturation were derived from the optical property data using a novel method that employed a priori spectral information t...

journal_title：Physics in medicine and biology

authors： Durduran T,Choe R,Culver JP,Zubkov L,Holboke MJ,Giammarco J,Chance B,Yodh AG

更新日期：2002-08-21 00:00:00

abstract：PURPOSE:A system for long-length intraoperative imaging is reported based on longitudinal motion of an O-arm gantry featuring a multi-slot collimator. We assess the utility of long-length tomosynthesis and the geometric accuracy of 3D image registration for surgical guidance and evaluation of long spinal constructs. M...

journal_title：Physics in medicine and biology

authors： Zhang X,Uneri A,Wu P,Ketcha MD,Jones C,Huang Y,Lo SL,Helm PA,Siewerdsen JH

更新日期：2021-01-21 00:00:00

abstract：:The in vivo electric conductivity (σ) values of tissue are essential for accurate electromagnetic simulations and specific absorption rate (SAR) assessment for applications such as thermal dose computations in hyperthermia. Currently used σ-values are mostly based on ex vivo measurements. In this study the conductivit...

journal_title：Physics in medicine and biology

authors： Balidemaj E,de Boer P,van Lier AL,Remis RF,Stalpers LJ,Westerveld GH,Nederveen AJ,van den Berg CA,Crezee J

更新日期：2016-02-21 00:00:00

abstract：:In this paper, the influence of a dynamic variation in the ambient pressure on the subharmonic response of phospholipid-coated microbubbles was investigated. The ambient pressure in water was modulated by a 2.5 kHz acoustic wave with a peak amplitude of 15 kPa. We investigated the fundamental and subharmonic emissions...

journal_title：Physics in medicine and biology

authors： Faez T,Renaud G,Defontaine M,Calle S,de Jong N

更新日期：2011-10-07 00:00:00

abstract：:We discuss the use of terahertz time domain spectroscopy for studies of conformational flexibility and conformational change in biomolecules. Protein structural dynamics are vital to biological function with protein flexibility affecting enzymatic reaction rates and sensory transduction cycling times. Conformational m...

journal_title：Physics in medicine and biology

authors： Markelz A,Whitmire S,Hillebrecht J,Birge R

更新日期：2002-11-07 00:00:00

abstract：:We extend the theory of three-dimensional (3D) tomographic intensity modulated radiation therapy (IMRT). The geometry consists of two-dimensional modulated beams on a sphere centred in the tumour. The theory provides an efficient algorithm for computing beam modulation patterns that approximately 'reconstruct' the pre...

journal_title：Physics in medicine and biology

authors： Levine RY,Braunstein M

更新日期：2002-03-07 00:00:00

abstract：:Dynamic contrast-enhanced computed tomography (DCE-CT) is an imaging tool that aids in evaluating functional characteristics of tissue at different stages of disease management: diagnostic, radiation treatment planning, treatment effectiveness, and monitoring. Clinical validation of DCE-derived perfusion parameters re...

journal_title：Physics in medicine and biology

authors： Peladeau-Pigeon M,Coolens C

更新日期：2013-09-07 00:00:00

abstract：:Recent studies of the minute morphology of the skin by optical coherence tomography revealed that the sweat ducts in human skin are helically shaped tubes, filled with a conductive aqueous solution. This, together with the fact that the dielectric permittivity of the dermis is higher than that of the epidermis, brings...

journal_title：Physics in medicine and biology

authors： Feldman Y,Puzenko A,Ben Ishai P,Caduff A,Davidovich I,Sakran F,Agranat AJ

更新日期：2009-06-07 00:00:00

abstract：:Measuring spin-spin relaxation times (T2) by quantitative MR imaging represents a potentially efficient tool to evaluate the physicochemical properties of various media. However, noise in MR images is responsible for uncertainties in the determination of T2 relaxation times, which limits the accuracy of parametric tis...

journal_title：Physics in medicine and biology

authors： Gensanne D,Josse G,Lagarde JM,Vincensini D

更新日期：2006-06-07 00:00:00

abstract：:This work aims to evaluate the predictive strength of the relative seriality, parallel and Lyman-Kutcher-Burman (LKB) normal tissue complication probability (NTCP) models regarding the incidence of radiation pneumonitis (RP), in a group of patients following lung cancer radiotherapy and also to examine their correlati...

journal_title：Physics in medicine and biology

authors： Tsougos I,Nilsson P,Theodorou K,Kjellén E,Ewers SB,Jarlman O,Lind BK,Kappas C,Mavroidis P

更新日期：2007-02-21 00:00:00

abstract：:Quality control (QC) data of radiotherapy linear accelerators, collected by Helsinki University Central Hospital between the years 2000 and 2004, were analysed. The goal was to provide information for the evaluation and elaboration of QC of accelerator outputs and to propose a method for QC data analysis. Short- and l...

journal_title：Physics in medicine and biology

authors： Kapanen M,Tenhunen M,Hämäläinen T,Sipilä P,Parkkinen R,Järvinen H

更新日期：2006-07-21 00:00:00

abstract：:A Monte Carlo model of a novel electronic portal imaging device (EPID) has been developed using Geant4 and its performance for imaging and dosimetry applications in radiotherapy has been characterised. The EPID geometry is based on a physical prototype under ongoing investigation and comprises an array of plastic scin...

journal_title：Physics in medicine and biology

authors： Blake SJ,McNamara AL,Vial P,Holloway L,Kuncic Z

更新日期：2014-11-21 00:00:00

abstract：:Diffusion tensor - magnetic resonance electrical impedance tomography (DT-MREIT) is an imaging modality to obtain low-frequency anisotropic conductivity distribution employing diffusion tensor imaging (DTI) and magnetic resonance electrical impedance tomography (MREIT) techniques. DT-MREIT is based on the linear relat...

journal_title：Physics in medicine and biology

authors： Sadighi M,Sisman M,Acikgoz BC,Eroglu HH,Eyuboglu BM

更新日期：2021-01-20 00:00:00

abstract：:An important aspect of robotic radiation therapy is active compensation of target motion. Recently, ultrasound has been proposed to obtain real-time volumetric images of abdominal organ motion. One approach to realize flexible probe placement throughout the treatment fraction is based on a robotic arm holding the ultr...

journal_title：Physics in medicine and biology

authors： Schlüter M,Fürweger C,Schlaefer A

更新日期：2019-10-04 00:00:00

abstract：:We comment on a previous article by Zhang and Newhauser (2009 Phys. Med. Biol. 54 1383-95) which presents several approximate ways of computing the water equivalent of an arbitrary degrader. First, we present a simple exact method which depends only on the range-energy relation of water and of the degrader material. S...

journal_title：Physics in medicine and biology

authors： Gottschalk B

更新日期：2010-05-07 00:00:00

abstract：:Scatter correction is a prerequisite for quantitative SPECT, but potentially increases noise. Monte Carlo simulations (EGS4) and physical phantom measurements were used to compare accuracy and noise properties of two scatter correction techniques: the triple-energy window (TEW), and the transmission dependent convolut...

journal_title：Physics in medicine and biology

authors： Narita Y,Eberl S,Iida H,Hutton BF,Braun M,Nakamura T,Bautovich G

更新日期：1996-11-01 00:00:00

abstract：:We model the heterogeneous response to radiation of multicellular tumour spheroids assuming position- and volume-dependent radiosensitivity. We propose a method to calculate the overall radiosensitivity parameters to obtain the surviving fraction of tumours. A mathematical model of a spherical tumour with a hypoxic co...

journal_title：Physics in medicine and biology

authors： Horas JA,Olguin OR,Rizzotto MG

更新日期：2005-04-21 00:00:00