Analysis of quality control data of eight modern radiotherapy linear accelerators: the short- and long-term behaviours of the outputs and the reproducibility of quality control measurements.

Abstract:

:Quality control (QC) data of radiotherapy linear accelerators, collected by Helsinki University Central Hospital between the years 2000 and 2004, were analysed. The goal was to provide information for the evaluation and elaboration of QC of accelerator outputs and to propose a method for QC data analysis. Short- and long-term drifts in outputs were quantified by fitting empirical mathematical models to the QC measurements. Normally, long-term drifts were well (< or =1%) modelled by either a straight line or a single-exponential function. A drift of 2% occurred in 18 +/- 12 months. The shortest drift times of only 2-3 months were observed for some new accelerators just after the commissioning but they stabilized during the first 2-3 years. The short-term reproducibility and the long-term stability of local constancy checks, carried out with a sealed plane parallel ion chamber, were also estimated by fitting empirical models to the QC measurements. The reproducibility was 0.2-0.5% depending on the positioning practice of a device. Long-term instabilities of about 0.3%/month were observed for some checking devices. The reproducibility of local absorbed dose measurements was estimated to be about 0.5%. The proposed empirical model fitting of QC data facilitates the recognition of erroneous QC measurements and abnormal output behaviour, caused by malfunctions, offering a tool to improve dose control.

journal_name

Phys Med Biol

authors

Kapanen M,Tenhunen M,Hämäläinen T,Sipilä P,Parkkinen R,Järvinen H

doi

10.1088/0031-9155/51/14/020

subject

Has Abstract

pub_date

2006-07-21 00:00:00

pages

3581-92

issue

14

eissn

0031-9155

issn

1361-6560

pii

S0031-9155(06)14327-4

journal_volume

51

pub_type

杂志文章
  • The importance of radiometer angular response for ultraviolet phototherapy dosimetry.

    abstract::The influence of the angular response of radiometer probes on measurements of irradiance in ultraviolet phototherapy has been studied. Irradiance measurements were made using nine ultraviolet (UV) radiometers employed by phototherapy centres in Scotland and Northern Ireland, and compared with measurements made using t...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/44/4/003

    authors: Martin CJ,Currie GD,Pye SD

    更新日期:1999-04-01 00:00:00

  • Development and evaluation of a deep learning based artificial intelligence for automatic identification of gold fiducial markers in an MRI-only prostate radiotherapy workflow.

    abstract::Identification of prostate gold fiducial markers in magnetic resonance imaging (MRI) images is challenging when CT images are not available, due to misclassifications from intra-prostatic calcifications. It is also a time consuming task and automated identification methods have been suggested as an improvement for bot...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/abb0f9

    authors: Gustafsson CJ,Swärd J,Adalbjörnsson SI,Jakobsson A,Olsson LE

    更新日期:2020-11-12 00:00:00

  • A spectral approach to ultrasonic scattering from human tissue: methods, objectives and backscattering measurements.

    abstract::The dearth of information on the physical processes involved in the propagation of ultrasound in tissue and the growing need for such information are discussed. The physical nature of the ultrasonic diagnostic process in considered in terms of a wave phenomenon and the limitations and advantages of frequency spectral ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/20/5/009

    authors: Chivers RC,Hill CR

    更新日期:1975-09-01 00:00:00

  • Extended three-compartment model for the transport and distribution of Hippuran.

    abstract::The distribution and transport of Hippuran is discussed. The activity leaving both kidneys has been calculated and compared with the bladder activity. It is shown that the Impulse Response Function of the ureter and bladder may be obtained by deconvolution, and data are presented relating to studies on one patient. ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/26/2/002

    authors: Knesaurek K,Spaventi S

    更新日期:1981-03-01 00:00:00

  • Detour factors in water and plastic phantoms and their use for range and depth scaling in electron-beam dosimetry.

    abstract::Average penetration depths and detour factors of 1-50 MeV electrons in water and plastic materials have been computed by means of analytical calculation, within the continuous-slowing-down approximation and including multiple scattering, and using the Monte Carlo codes ITS and PENELOPE. Results are compared to detour ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/41/7/004

    authors: Fernández-Varea JM,Andreo P,Tabata T

    更新日期:1996-07-01 00:00:00

  • Quality assurance in brachytherapy: the displacement effect in the vicinity of 60Co and 192Ir brachytherapy sources.

    abstract::Cylindrical ionization chambers with varying radii have been used to determine the displacement effect at distances between 10 mm and 40 mm from 60Co and 192Ir brachytherapy sources. Agreement with published values of the displacement factor for external 60Co beams is obtained. The shift between the centre of the ioni...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/38/10/009

    authors: Tölli H,Johansson KA

    更新日期:1993-10-01 00:00:00

  • Commissioning of pencil beam and Monte Carlo dose engines for non-isocentric treatments in scanned proton beam therapy.

    abstract::This work describes the dosimetric commissioning of the treatment planning system (TPS) RayStation v6.1 from RaySearch Laboratories (Stockholm, Sweden) for a synchrotron-based scanned proton beam delivery with isocentric and non-isocentric setups at MedAustron. Focus was on the comparison of the pencil beam (PBv4.1) a...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab3557

    authors: Carlino A,Böhlen T,Vatnitsky S,Grevillot L,Osorio J,Dreindl R,Palmans H,Stock M,Kragl G

    更新日期:2019-08-28 00:00:00

  • Use of forward projection to correct patient motion during SPECT imaging.

    abstract::We have developed an iterative method to correct axial and tangential patient motion occurring during tomographic acquisition. The method uses axial images reconstructed from the uncorrected projection images, which are then forward projected to form a basis for registering the original planar images and, in the proce...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/43/1/011

    authors: Lee KJ,Barber DC

    更新日期:1998-01-01 00:00:00

  • Simultaneous optimization of RBE-weighted dose and nanometric ionization distributions in treatment planning with carbon ions.

    abstract::Inverse treatment planning in intensity modulated particle therapy (IMPT) with scanned carbon-ion beams is currently based on the optimization of RBE-weighted dose to satisfy requirements of target coverage and limited toxicity to organs-at-risk (OARs) and healthy tissues. There are many feasible IMPT plans that meet ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aaf400

    authors: Burigo LN,Ramos-Méndez J,Bangert M,Schulte RW,Faddegon B

    更新日期:2019-01-04 00:00:00

  • SpekCalc: a program to calculate photon spectra from tungsten anode x-ray tubes.

    abstract::A software program, SpekCalc, is presented for the calculation of x-ray spectra from tungsten anode x-ray tubes. SpekCalc was designed primarily for use in a medical physics context, for both research and education purposes, but may also be of interest to those working with x-ray tubes in industry. Noteworthy is the p...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/54/19/N01

    authors: Poludniowski G,Landry G,DeBlois F,Evans PM,Verhaegen F

    更新日期:2009-10-07 00:00:00

  • The noise power spectrum of CT images.

    abstract::An expression for the noise power spectrum of images reconstructed by the discrete filtered backprojection algorithm has been derived. The formulation explicitly includes sampling within the projections, angular sampling, and the two-dimensional sampling implicit in the discrete representation of the image. The effect...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/32/5/003

    authors: Kijewski MF,Judy PF

    更新日期:1987-05-01 00:00:00

  • Variability among polysulphone calibration curves.

    abstract::Within an epidemiological study regarding the correlation between skin pathologies and personal ultraviolet (UV) exposure due to solar radiation, 14 field campaigns using polysulphone (PS) dosemeters were carried out at three different Italian sites (urban, semi-rural and rural) in every season of the year. A polysulp...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/51/17/019

    authors: Casale GR,Borra M,Colosimo A,Colucci M,Militello A,Siani AM,Sisto R

    更新日期:2006-09-07 00:00:00

  • Medical staff extremity dosimetry in CT fluoroscopy: an anthropomorphic hand voxel phantom study.

    abstract::This work aims to contribute to the study of the radiation dose distribution delivered to the hands of medical staff members during a general computed tomographic (CT) fluoroscopic guided procedure. In this study, both Monte Carlo simulations and measurements were performed. For free-in-air and computed tomography dos...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/58/16/5433

    authors: Figueira C,Becker F,Blunck C,DiMaria S,Baptista M,Esteves B,Paulo G,Santos J,Teles P,Vaz P

    更新日期:2013-08-21 00:00:00

  • Comparative Monte Carlo study on the performance of integration- and list-mode detector configurations for carbon ion computed tomography.

    abstract::Ion beam therapy offers the possibility of a highly conformal tumor-dose distribution; however, this technique is extremely sensitive to inaccuracies in the treatment procedures. Ambiguities in the conversion of Hounsfield units of the treatment planning x-ray CT to relative stopping power (RSP) can cause uncertaintie...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa5602

    authors: Meyer S,Gianoli C,Magallanes L,Kopp B,Tessonnier T,Landry G,Dedes G,Voss B,Parodi K

    更新日期:2017-02-07 00:00:00

  • An investigation of a PRESAGE® in vivo dosimeter for brachytherapy.

    abstract::Determining accurate in vivo dosimetry in brachytherapy treatment with high dose gradients is challenging. Here we introduce, investigate, and characterize a novel in vivo dosimeter and readout technique with the potential to address this problem. A cylindrical (4 mm × 20 mm) tissue equivalent radiochromic dosimeter P...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/59/14/3893

    authors: Vidovic AK,Juang T,Meltsner S,Adamovics J,Chino J,Steffey B,Craciunescu O,Oldham M

    更新日期:2014-07-21 00:00:00

  • Monte Carlo calculated and experimentally determined output correction factors for small field detectors in Leksell Gamma Knife Perfexion beams.

    abstract::The measurement of output factors (OF) for the small photon beams generated by Leksell Gamma Knife® (LGK) radiotherapy units is a challenge for the physicist due to the under or over estimation of these factors by a vast majority of the detectors commercially available. Output correction factors, introduced in the int...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/10/3959

    authors: Benmakhlouf H,Johansson J,Paddick I,Andreo P

    更新日期:2015-05-21 00:00:00

  • Respiratory motion prediction by using the adaptive neuro fuzzy inference system (ANFIS).

    abstract::The quality of radiation therapy delivered for treating cancer patients is related to set-up errors and organ motion. Due to the margins needed to ensure adequate target coverage, many breast cancer patients have been shown to develop late side effects such as pneumonitis and cardiac damage. Breathing-adapted radiatio...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/50/19/020

    authors: Kakar M,Nyström H,Aarup LR,Nøttrup TJ,Olsen DR

    更新日期:2005-10-07 00:00:00

  • Optimization of image quality and dose for Varian aS500 electronic portal imaging devices (EPIDs).

    abstract::This study was carried out to investigate whether the electronic portal imaging (EPI) acquisition process could be optimized, and as a result tolerance and action levels be set for the PIPSPro QC-3V phantom image quality assessment. The aim of the optimization process was to reduce the dose delivered to the patient wh...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/52/23/006

    authors: McGarry CK,Grattan MW,Cosgrove VP

    更新日期:2007-12-07 00:00:00

  • The modelling of biological systems in three dimensions using the time domain finite-difference method: I. The implementation of the model.

    abstract::A computer method has been developed which uses the time domain finite-difference (TDFD) algorithm to calculate the deposition of the electromagnetic (EM) field in three-dimensional biological models. This, the first of two papers, describes the algorithm and the computer programs developed. The method is demonstrated...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/31/11/006

    authors: Lau RW,Sheppard RJ

    更新日期:1986-11-01 00:00:00

  • Radiofrequency heating effects around resonant lengths of wire in MRI.

    abstract::Several recent reports agree that the potentially dangerous heating around extended wires or coaxial cables inside the bodycoil of a magnetic resonance imager is related to resonant effects. No quantitative description of this idea has been given so far. We analyse a simplified situation, where a straight metallic wir...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/47/16/312

    authors: Pictet J,Meuli R,Wicky S,van der Klink JJ

    更新日期:2002-08-21 00:00:00

  • Feasibility of replacing patient specific cutouts with a computer-controlled electron multileaf collimator.

    abstract::A motorized electron multileaf collimator (eMLC) was developed as an add-on device to the Varian linac for delivery of advanced electron beam therapy. It has previously been shown that electron beams collimated by an eMLC have very similar penumbra to those collimated by applicators and cutouts. Thus, manufacturing pa...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/58/16/5653

    authors: Eldib A,Jin L,Li J,Ma CM

    更新日期:2013-08-21 00:00:00

  • 4D VMAT, gated VMAT, and 3D VMAT for stereotactic body radiation therapy in lung.

    abstract::Four-dimensional volumetric modulated arc therapy (4D VMAT) is a treatment strategy for lung cancers that aims to exploit relative target and tissue motion to improve organ at risk (OAR) sparing. The algorithm incorporates the entire patient respiratory cycle using 4D CT data into the optimization process. Resulting t...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/58/4/749

    authors: Chin E,Loewen SK,Nichol A,Otto K

    更新日期:2013-02-21 00:00:00

  • Comparison of in vivo scintillation probes and gamma cameras for detection of small, deep tumours.

    abstract::An in vivo probe was compared with a gamma camera for the task of detecting radiolabelled tumour models in a water phantom. The probe, which contained a 1 cm diameter NaI(T1) detector, was designed and used by us for surgical staging studies of gynaecological patients. Tumours were spherical sources of different sizes...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/34/6/008

    authors: Barber HB,Barrett HH,Woolfenden JM,Myers KJ,Hickernell TS

    更新日期:1989-06-01 00:00:00

  • Intensity modulated radiation therapy for oropharyngeal cancer: the sensitivity of plan objectives and constraints to set-up uncertainty.

    abstract::The goal of this study was to assess the impact of set-up uncertainty on compliance with the objectives and constraints of an intensity modulated radiation therapy protocol for early stage cancer of the oropharynx. As the convolution approach to the quantitative study of set-up uncertainties cannot accommodate either ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/50/15/003

    authors: Ploquin N,Song W,Lau H,Dunscombe P

    更新日期:2005-08-07 00:00:00

  • Mathematical modelling of the human cardiovascular system in the presence of stenosis.

    abstract::This paper reports a theoretical study on the distribution of blood flow in the human cardiovascular system when one or more blood vessels are affected by stenosis. The analysis employs a mathematical model of the entire system based on the finite element method. The arterial-venous network is represented by a large n...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/38/3/004

    authors: Sud VK,Srinivasan RS,Charles JB,Bungo MW

    更新日期:1993-03-01 00:00:00

  • Investigation of the refractive index decrement of 3D printing materials for manufacturing breast phantoms for phase contrast imaging.

    abstract::3D breast modelling for 2D and 3D breast x-ray imaging would benefit from the availability of digital and physical phantoms that reproduce accurately the complexity of the breast anatomy. While a number of groups have produced digital phantoms with increasing level of complexity, physical phantoms reproducing that sof...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab0670

    authors: Esposito G,Mettivier G,Bliznakova K,Bliznakov Z,Bosmans H,Bravin A,Buliev I,Di Lillo F,Ivanov D,Minutillo M,Sarno A,Vignero J,Russo P

    更新日期:2019-03-27 00:00:00

  • Characterization of the electromagnetic near-field absorption in layered biological tissue in the frequency range from 30 MHz to 6,000 MHz.

    abstract::Currently, standards for the compliance testing of wireless devices are being extended to cover a wider frequency band and different usage patterns of mobile phones as well as of novel body-worn and handheld devices. As a consequence, not only the head but also strongly varying tissue distributions of the body are exp...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/51/19/014

    authors: Christ A,Samaras T,Klingenböck A,Kuster N

    更新日期:2006-10-07 00:00:00

  • Dosimetry for the MRI accelerator: the impact of a magnetic field on the response of a Farmer NE2571 ionization chamber.

    abstract::The UMC Utrecht is constructing a 1.5 T MRI scanner integrated with a linear accelerator (Lagendijk et al 2008 Radiother. Oncol. 86 25-9). The goal of this device is to facilitate soft-tissue contrast based image-guided radiotherapy, in order to escalate the dose to the tumour while sparing surrounding normal tissues....

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/54/10/002

    authors: Meijsing I,Raaymakers BW,Raaijmakers AJ,Kok JG,Hogeweg L,Liu B,Lagendijk JJ

    更新日期:2009-05-21 00:00:00

  • A potential method for in vivo range verification in proton therapy treatment.

    abstract::Proton therapy potentially offers excellent dose conformality and reduction in integral dose. The superior dose distribution is, however, much more sensitive to the radiological depth along the beam path than for photon fields. Variations in this depth due to inaccurate planning calculation, setup uncertainty, respira...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/53/5/016

    authors: Lu HM

    更新日期:2008-03-07 00:00:00

  • The effect of temporal HU variations on the uncertainty of dose recalculations performed on MVCT images.

    abstract::Over the course of radiation therapy, a patient's anatomy may change substantially. The relatively recent addition of frequent in-room imaging to assist with patient localization has provided a database of images that may be used to recalculate dose distributions for adaptive radiotherapy purposes. The TomoTherapy Hi-...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/56/24/010

    authors: Pukala J,Meeks SL,Bova FJ,Langen KM

    更新日期:2011-12-21 00:00:00