The exponential edge-gradient effect in x-ray computed tomography.

abstract：:The purpose of this study is to develop an adaptive prior knowledge guided image estimation technique to reduce the scan angle needed in the limited-angle intrafraction verification (LIVE) system for 4D-CBCT reconstruction. The LIVE system has been previously developed to reconstruct 4D volumetric images on-the-fly du...

journal_title：Physics in medicine and biology

authors： Zhang Y,Yin FF,Zhang Y,Ren L

更新日期：2017-05-07 00:00:00

abstract：:An accurate, low noise estimate of photon attenuation in the subject is required for quantitative microPET studies of molecular tracer distributions in vivo. In this work, several transmission-based measurement techniques were compared, including coincidence mode with and without rod windowing, singles mode with two d...

journal_title：Physics in medicine and biology

authors： Lehnert W,Meikle SR,Siegel S,Newport D,Banati RB,Rosenfeld AB

更新日期：2006-08-21 00:00:00

abstract：:Magnetoencephalography (MEG) is a non-invasive functional imaging modality based on the measurement of the external magnetic field produced by neural current sources within the brain. The reconstruction of the underlying sources is a severely ill-posed inverse problem typically tackled using either low-dimensional par...

journal_title：Physics in medicine and biology

authors： Jerbi K,Mosher JC,Baillet S,Leahy RM

更新日期：2002-02-21 00:00:00

abstract：:A method to determine the spectrum of a clinical photon beam from measured depth-dose data is described. At shallow depths, where the range of Compton-generated electrons increases rapidly with photon energy, the depth dose provides the information to discriminate the spectral contributions. To minimize the influence ...

journal_title：Physics in medicine and biology

authors： Bloch P,Altschuler MD,Bjärngard BE,Kassaee A,McDonough J

更新日期：2000-01-01 00:00:00

abstract：:The development of alpha-emitting radiopharmaceuticals using 211At requires quantitative determination of the time-dependent nature of the 211At biodistribution. However, imaging-based methods for acquiring this information with 211At have not found wide-spread use because of its low abundance of decay emissions suita...

journal_title：Physics in medicine and biology

authors： Crawford JR,Robertson AKH,Yang H,Rodríguez-Rodríguez C,Esquinas PL,Kunz P,Blinder S,Sossi V,Schaffer P,Ruth TJ

更新日期：2018-02-21 00:00:00

abstract：:The relative biological effectiveness (RBE) of protons varies with multiple physical and biological factors. Phenomenological RBE models have been developed to include such factors in the estimation of a variable RBE, in contrast to the clinically applied constant RBE of 1.1. In this study, eleven published phenomenol...

journal_title：Physics in medicine and biology

authors： Rørvik E,Fjæra LF,Dahle TJ,Dale JE,Engeseth GM,Stokkevåg CH,Thörnqvist S,Ytre-Hauge KS

更新日期：2018-09-13 00:00:00

abstract：:This study introduces a practical four-dimensional (4D) planning scheme of IMAT using 4D computed tomography (4D CT) for planning tumor tracking with dynamic multileaf beam collimation. We assume that patients can breathe regularly, i.e. the same way as during 4D CT with an unchanged period and amplitude, and that the...

journal_title：Physics in medicine and biology

authors： Niu Y,Betzel GT,Yang X,Gui M,Parke WC,Yi B,Yu CX

更新日期：2017-02-21 00:00:00

abstract：:Skin toxicity has been reported for IMRT of head and neck cancer. The purpose of this study was to investigate the dose in the build-up region delivered by a 6 MV treatment plan for which important skin toxicity was observed. We also investigated if the different designs of the treatment head of an Elekta and a Varian...

journal_title：Physics in medicine and biology

authors： Paelinck L,De Wagter C,Van Esch A,Duthoy W,Depuydt T,De Neve W

更新日期：2005-02-07 00:00:00

abstract：:Methods based on magnetic resonance imaging for the measurement of three-dimensional distributions of radiation dose are highly developed. However, relatively little work has been done on optical computed tomography (OCT). This paper describes a new OCT scanner based on a broad beam light source and a two-dimensional ...

journal_title：Physics in medicine and biology

authors： Doran SJ,Koerkamp KK,Bero MA,Jenneson P,Morton EJ,Gilboy WB

更新日期：2001-12-01 00:00:00

abstract：:Values of the relative permittivity and conductivity of the rabbit retina and lens have been measured between 10 MHz and 10 GHz over the temperature range 20 to -20 degrees C. As the temperature was lowered from 20 degrees C the dielectric parameters changed smoothly until -9 degrees C where freezing occurred. At this...

journal_title：Physics in medicine and biology

authors： Gabriel C,Grant EH

更新日期：1985-09-01 00:00:00

abstract：:This study investigated the relationship between the specific absorption rate and temperature elevation in an anatomically-based model named NORMAN for exposure to radio-frequency far fields in the ICNIRP guidelines (1998 Health Phys. 74 494-522). The finite-difference time-domain method is used for analyzing the elec...

journal_title：Physics in medicine and biology

authors： Hirata A,Asano T,Fujiwara O

更新日期：2007-08-21 00:00:00

abstract：:The Hug-Kellerer (H-K) equation is one of the earliest proposed radiation cell survival curves. We examine this equation in view of the recent perceived need for a universal cell survival curve which would be applicable to single radiation fractions at high doses. We derive relationships between the three parameters o...

journal_title：Physics in medicine and biology

authors： Ekstrand KE

更新日期：2010-05-21 00:00:00

abstract：:This study investigated the temperature elevation in the eye of anatomically based human head models for plane-wave exposures. The finite-difference time-domain method is used for analyzing electromagnetic absorption and temperature elevation. The eyes in the anatomic models have average dimensions and weight. Computa...

journal_title：Physics in medicine and biology

authors： Hirata A,Watanabe S,Fujiwara O,Kojima M,Sasaki K,Shiozawa T

更新日期：2007-11-07 00:00:00

abstract：:A novel digital x-ray detector has been assembled. The imaging system is based on a phosphor-coated charge-coupled device (CCD) obtained by direct deposition of a gadolinium oxysulphide scintillator onto the detector surface. The modulation transfer function has been measured along the two directions of the digital co...

journal_title：Physics in medicine and biology

authors： Gambaccini M,Taibi A,Del Guerra A,Marziani M,Tuffanelli A

更新日期：1996-12-01 00:00:00

abstract：:Single monochromator charge-coupled device (CCD) array spectroradiometers have the advantage of ease of use and speed compared with double grating instruments. Their inherently inferior stray-light rejection, however, can critically affect their accuracy in phototherapy and research-related dosimetry applications. Thi...

journal_title：Physics in medicine and biology

authors： Coleman A,Sarkany R,Walker S

更新日期：2008-09-21 00:00:00

abstract：:For the first time the absolute photon mass energy-absorption coefficient of air in the energy range of 10 to 60 keV has been measured with relative standard uncertainties below 1%, considerably smaller than those of up to 2% assumed for calculated data. For monochromatized synchrotron radiation from the electron stor...

journal_title：Physics in medicine and biology

authors： Buhr H,Büermann L,Gerlach M,Krumrey M,Rabus H

更新日期：2012-12-21 00:00:00

abstract：:Mean glandular dose is the quantity used for dosimetry in mammography and depends on breast-related characteristics, such as thickness and density, and on the x-ray spectrum used for breast imaging. This work aims to present an experimentally-based method to derive polyenergetic normalized glandular dose coefficients ...

journal_title：Physics in medicine and biology

authors： Santos JC,Tomal A,de Barros N,Costa PR

更新日期：2019-05-10 00:00:00

abstract：:We combine two near-infrared diffuse optical techniques to study variations of blood flow, haemoglobin concentration, and blood oxygen saturation in the functioning rat brain. Diffuse correlation spectroscopy (or flowmetry) monitors changes in the cerebral blood flow, without the use of the principles of tracer cleara...

journal_title：Physics in medicine and biology

authors： Cheung C,Culver JP,Takahashi K,Greenberg JH,Yodh AG

更新日期：2001-08-01 00:00:00

abstract：:The dielectric properties of glycerol, propylene glycol, ethylene glycol and dimethyl sulphoxide have been measured in various aqueous concentrations generally sufficient to allow supercooling rather than freezing. The temperature range investigated is from -80 degrees C to +20 degrees C and the frequency range is 100...

journal_title：Physics in medicine and biology

authors： Michelson SC,Evans S

更新日期：1996-10-01 00:00:00

abstract：:Output normalized dose profiles for asymmetric open photon fields has been calculated using a commercial treatment planning system (TPS) based on a dose-to-energy-fluence concept. The model does not require any additional measurements for off-axis fields. Calculations are compared with measurements for quadratic field...

journal_title：Physics in medicine and biology

authors： Hurkmans C,Knöös T,Nilsson P

更新日期：1996-08-01 00:00:00

abstract：:Cone-beam computed tomography (CBCT) has rapidly become a clinically useful imaging modality for image-guided radiation therapy. Unfortunately, CBCT images of the thorax are susceptible to artefacts due to scattered photons, beam hardening, lag in data acquisition, and respiratory motion during a slow scan. These limi...

journal_title：Physics in medicine and biology

authors： Disher B,Hajdok G,Wang A,Craig J,Gaede S,Battista JJ

更新日期：2013-06-21 00:00:00

abstract：:Awake and/or freely moving small animal single photon emission imaging allows the continuous study of molecules exhibiting slow kinetics without the need to restrain or anaesthetise the animals. Estimating motion free projections in freely moving small animal planar imaging can be considered as a limited angle tomogra...

journal_title：Physics in medicine and biology

authors： Angelis GI,Ryder WJ,Gillam JE,Boisson F,Kyme AZ,Fulton RR,Meikle SR,Kench PL

更新日期：2017-05-21 00:00:00

abstract：:This paper investigates the feasibility of a scanned cylindrical ultrasound system for producing uniform heating from the central to the superficial portions of the breast or localized heating within the breast at a specific location. The proposed system consists of plane ultrasound transducer(s) mounted on a scanned ...

journal_title：Physics in medicine and biology

authors： Ju KC,Tseng LT,Chen YY,Lin WL

更新日期：2006-02-07 00:00:00

abstract：:Determining plaque vulnerability is critical when selecting the most suitable treatment for patients with atherosclerotic plaque. Currently, clinical non-invasive ultrasound-based methods for plaque characterization are limited to visual assessment of plaque morphology and new quantitative methods are needed. In this ...

journal_title：Physics in medicine and biology

authors： Widman E,Maksuti E,Larsson D,Urban MW,Bjällmark A,Larsson M

更新日期：2015-04-21 00:00:00

abstract：:Breast-conserving surgery is a standard option for the treatment of patients with early-stage breast cancer. This form of surgery may result in incomplete excision of the tumor. Iodine-125 labeled titanium seeds are currently used in clinical practice to reduce the number of incomplete excisions. It seems likely that ...

journal_title：Physics in medicine and biology

authors： Arsenali B,de Jong HW,Viergever MA,Dickerscheid DB,Beijst C,Gilhuijs KG

更新日期：2015-10-07 00:00:00

abstract：:Beam tracking with scanned carbon ion radiotherapy achieves highly conformal target dose by steering carbon pencil beams to follow moving tumors using real-time magnetic deflection and range modulation. The purpose of this study was to evaluate the robustness of target dose coverage from beam tracking in light of posi...

journal_title：Physics in medicine and biology

authors： Eley JG,Newhauser WD,Richter D,Lüchtenborg R,Saito N,Bert C

更新日期：2015-02-21 00:00:00

abstract：:Hair loss is a feared side effect of chemotherapy treatment. It may be prevented by cooling the scalp during administration of cytostatics. The supposed mechanism is that by cooling the scalp, both temperature and perfusion are diminished, affecting drug supply and drug uptake in the hair follicle. However, the effect...

journal_title：Physics in medicine and biology

authors： Janssen FE,Van Leeuwen GM,Van Steenhoven AA

更新日期：2005-09-07 00:00:00

abstract：:An iterative Bayesian reconstruction algorithm for limited view angle tomography, or ectomography, based on the three-dimensional total variation (TV) norm has been developed. The TV norm has been described in the literature as a method for reducing noise in two-dimensional images while preserving edges, without intro...

journal_title：Physics in medicine and biology

authors： Persson M,Bone D,Elmqvist H

更新日期：2001-03-01 00:00:00

abstract：:We present a new version of STIR (Software for Tomographic Image Reconstruction), an open source object-oriented library implemented in C++ for 3D positron emission tomography reconstruction. This library has been designed such that it can be used for many algorithms and scanner geometries, while being portable to var...

journal_title：Physics in medicine and biology

authors： Thielemans K,Tsoumpas C,Mustafovic S,Beisel T,Aguiar P,Dikaios N,Jacobson MW

更新日期：2012-02-21 00:00:00

abstract：:Monitoring the spatio-temporal characteristics of microcirculation is crucial for studying the functional activities of biotissue and the mechanism of disease. However, conventional methods used to measure blood flow suffer from limited spatial resolution or the injection of exogenous substances or the need of scannin...

journal_title：Physics in medicine and biology

authors： Cheng H,Luo Q,Liu Q,Lu Q,Gong H,Zeng S

更新日期：2004-04-07 00:00:00