Laser speckle imaging of blood flow in microcirculation.

abstract：:Output normalized dose profiles for asymmetric open photon fields has been calculated using a commercial treatment planning system (TPS) based on a dose-to-energy-fluence concept. The model does not require any additional measurements for off-axis fields. Calculations are compared with measurements for quadratic field...

journal_title：Physics in medicine and biology

authors： Hurkmans C,Knöös T,Nilsson P

更新日期：1996-08-01 00:00:00

abstract：:A solid dynamic phantom with tissue-like optical properties is presented, which contains seven discrete targets impregnated with thermochromic pigment located at different depths from the surface. Changes in absorption are obtained in response to localized heating of the targets, simulating haemodynamic changes occurr...

journal_title：Physics in medicine and biology

authors： Correia T,Banga A,Everdell NL,Gibson AP,Hebden JC

更新日期：2009-10-21 00:00:00

abstract：:For treatments with dynamic intensity modulated radiotherapy (IMRT), the adjustment of multileaf collimator (MLC) parameters affecting both the optimization algorithm and dose distributions is crucial. The main parameters characterizing the MLC are the transmission (T) and the dosimetric leaf separation (DLS). The aim...

journal_title：Physics in medicine and biology

authors： Chauvet I,Petitfils A,Lehobey C,Kristner JY,Brunet Y,Lembrez R,Gaboriaud G,Mazal A,Zefkili S,Rosenwald JC

更新日期：2005-02-21 00:00:00

abstract：:Despite the early recognition of the potential of proton imaging to assist proton therapy (Cormack 1963 J. Appl. Phys. 34 2722), the modality is still removed from clinical practice, with various approaches in development. For proton-counting radiography applications such as computed tomography (CT), the water-equival...

journal_title：Physics in medicine and biology

authors： Poludniowski G,Allinson NM,Anaxagoras T,Esposito M,Green S,Manolopoulos S,Nieto-Camero J,Parker DJ,Price T,Evans PM

更新日期：2014-06-07 00:00:00

abstract：:A complete characterization of spongiosa (bone marrow plus trabecular bone) is required to calculate the absorbed dose to active bone marrow. Due to the complex microanatomy, it is necessary to apply non-conventional imaging methods in nuclear medicine. The aim of this study is validating a phantomless quantification ...

journal_title：Physics in medicine and biology

authors： Salas-Ramirez M,Tran-Gia J,Gbureck U,Kosmala A,Lassmann M

更新日期：2019-10-16 00:00:00

abstract：:The dependence of boron-dose enhancer (BDE) characteristics on dose protocol and 10B concentration was evaluated for BNCT using near-threshold 7Li(p,n)7Be direct neutrons. The treatable protocol depth (TPD) was utilized as an evaluation index. MCNP calculations were performed for near-threshold 7Li(p,n)7Be at a proton...

journal_title：Physics in medicine and biology

authors： Tanaka K,Kobayashi T,Bengua G,Nakagawa Y,Endo S,Hoshi M

更新日期：2005-01-07 00:00:00

abstract：:In carbon-ion radiotherapy, single-beam delivery each day in alternate directions has been common practice for efficient operation, taking advantage of the Bragg peak and the relative biological effectiveness (RBE) for uniform dose conformation to a tumor. Treatments are usually fractionated and treatment plans are ev...

journal_title：Physics in medicine and biology

authors： Kanematsu N,Inaniwa T

更新日期：2017-02-07 00:00:00

abstract：:DMSA imaging is carried out in nuclear medicine to assess the level of functional renal tissue in patients. This study investigated the use of an artificial neural network to perform diagnostic classification of these scans. Using the radiological report as the gold standard, the network was trained to classify DMSA s...

journal_title：Physics in medicine and biology

authors： Wright JW,Duguid R,McKiddie F,Staff RT

更新日期：2014-04-07 00:00:00

abstract：:Lung tumors treated in breath-hold are subject to inter- and intra-breath-hold variations, which makes tumor position monitoring during each breath-hold important. A markerless technique is desirable, but limited tumor visibility on kV images makes this challenging. We evaluated if template matching  +  triangulation ...

journal_title：Physics in medicine and biology

authors： Hazelaar C,Dahele M,Mostafavi H,van der Weide L,Slotman B,Verbakel W

更新日期：2018-05-29 00:00:00

abstract：:Multi-atlas segmentation (MAS) has been widely used to automate the delineation of organs at risk (OARs) for radiotherapy. Label fusion is a crucial step in MAS to cope with the segmentation variabilities among multiple atlases. However, most existing label fusion methods do not consider the potential dosimetric impac...

journal_title：Physics in medicine and biology

authors： Chang J,Tian Z,Lu W,Gu X,Chen M,Jiang SB

更新日期：2017-05-07 00:00:00

abstract：:This work discusses the substitution of a gelatine physical gel matrix with a matrix made of poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) (Pluronic F-127) in five 3D radiotherapy polymer gel dosimeters: MAGAT, PAGAT, NIPAM, VIPARnd (VIP) and VIPARCT (VIC). The current research outcomes s...

journal_title：Physics in medicine and biology

authors： Jaszczak M,Wach R,Maras P,Dudek M,Kozicki M

更新日期：2018-09-06 00:00:00

abstract：:We present a novel linear programming (LP) based approach for efficiently solving the intensity modulated radiation therapy (IMRT) fluence-map optimization (FMO) problem to global optimality. Our model overcomes the apparent limitations of a linear-programming approach by approximating any convex objective function by...

journal_title：Physics in medicine and biology

authors： Romeijn HE,Ahuja RK,Dempsey JF,Kumar A,Li JG

更新日期：2003-11-07 00:00:00

abstract：:MRI-guided prostate biopsy in conventional closed-bore scanners requires transferring the patient outside the bore during needle insertion due to the constrained in-bore space, causing a safety hazard and limiting image feedback. To address this issue, we present our custom-made in-bore setup and software to support M...

journal_title：Physics in medicine and biology

authors： Tokuda J,Tuncali K,Iordachita I,Song SE,Fedorov A,Oguro S,Lasso A,Fennessy FM,Tempany CM,Hata N

更新日期：2012-09-21 00:00:00

abstract：:Crucial to all cancer therapy modalities is a strong correlation between treatment and effect. Predictability of therapy success/failure allows for the optimization of treatment protocol and aids in the decision of whether additional treatment is necessary to prevent tumour progression. This work evaluated the relatio...

journal_title：Physics in medicine and biology

authors： Hrycushko BA,Ware S,Li S,Bao A

更新日期：2011-09-07 00:00:00

abstract：:A novel transmission detector (IBA Dosimetry, Germany) developed as an IMRT quality assurance tool, intended for in vivo patient dose measurements, is studied here. The goal of this investigation is to use Monte Carlo techniques to characterize treatment beam parameters in the presence of the detector and to compare t...

journal_title：Physics in medicine and biology

authors： Asuni G,Jensen JM,McCurdy BM

更新日期：2011-02-21 00:00:00

abstract：:The purpose of this study was the evaluation of the impact of a variable relative biological effectiveness (RBE) compared to a constant RBE value of 1.1 in proton therapy prostate trials due to uncertainties in α/β ratio. Twenty patients receiving passive scattered proton therapy (PSPT) and fifteen patients receiving ...

journal_title：Physics in medicine and biology

authors： Marteinsdottir M,Paganetti H

更新日期：2019-06-05 00:00:00

abstract：:In recent years, there has been an increase in the popularity of light-emitting diode (LED)-based, battery-powered transilluminators (BPTs) for facilitating transdermal vascular access in adults and neonates. BPTs are believed to have lower potential for inducing skin burns than prior devices based on high-power broad...

journal_title：Physics in medicine and biology

authors： Pfefer TJ,Mehrabi A,James R,Landry R,Weininger S,Chang I,Kaufman D,Miller S

更新日期：2009-11-21 00:00:00

abstract：:We describe an improved algorithm for localising equivalent sources of biomagnetic fields in the human brain. The algorithm is an improvement over the sphere model in that it considers two distinct surfaces: an ellipsoid, to model the region of the skull on which the sensors are placed, and a sphere as the medium in w...

journal_title：Physics in medicine and biology

authors： Pistella F,Barone P,Narici L,Ocello N,Pizzella V,Romani GL

更新日期：1987-01-01 00:00:00

abstract：:The objective of this study was to be able to distinguish between healthy skin tissue and malignant ones, furthermore determining a unique pattern of roughness for each skin lesion by microtopographic analysis of the skin surface of Mexican patients during the period from April to October 2002. The standard technique ...

journal_title：Physics in medicine and biology

authors： del Carmen López Pacheco M,da Cunha Martins-Costa MF,Zapata AJ,Cherit JD,Gallegos ER

更新日期：2005-12-07 00:00:00

abstract：:Factors influencing the precision of measuring changes in the calcium content of sections of bone, including vertebrae, using reactor neutrons for partial body in vivo activation analysis have been examined and quantified. These factors include (a) the choice of incidient neutron spectrum, (b) the uniformity of activa...

journal_title：Physics in medicine and biology

authors： Boddy K,Glaros D,Robertson I

更新日期：1975-01-01 00:00:00

abstract：:A Monte Carlo computational model of a fluoroscopic imaging chain was used for deriving optimal technique factors for paediatric fluoroscopy. The optimal technique was defined as the one that minimizes the absorbed dose (or dose rate) in the patient with a constraint of constant image quality. Image quality was assess...

journal_title：Physics in medicine and biology

authors： Tapiovaara MJ,Sandborg M,Dance DR

更新日期：1999-02-01 00:00:00

abstract：:Many applications in medical imaging include image registration for matching of images from the same or different modalities. In the case of full data sampling, the respective reconstructed images are usually of such a good image quality that standard deformable volume-to-volume (3D-3D) registration approaches can be ...

journal_title：Physics in medicine and biology

authors： Flach B,Brehm M,Sawall S,Kachelrieß M

更新日期：2014-12-21 00:00:00

abstract：:The beam quality correction factor k Q for megavoltage photon beams has been calculated for eight PTW (Freiburg, Germany) ionization chambers (Farmer chambers PTW30010, PTW30011, PTW30012, and PTW30013, Semiflex 3D chambers PTW31021, PTW31010, and PTW31013, and the PinPoint 3D chamber PTW31016). Simulations performed ...

journal_title：Physics in medicine and biology

authors： Giménez-Alventosa V,Giménez V,Ballester F,Vijande J,Andreo P

更新日期：2020-10-07 00:00:00

abstract：:In this paper, the influence of a dynamic variation in the ambient pressure on the subharmonic response of phospholipid-coated microbubbles was investigated. The ambient pressure in water was modulated by a 2.5 kHz acoustic wave with a peak amplitude of 15 kPa. We investigated the fundamental and subharmonic emissions...

journal_title：Physics in medicine and biology

authors： Faez T,Renaud G,Defontaine M,Calle S,de Jong N

更新日期：2011-10-07 00:00:00

abstract：:A Monte Carlo model of a novel electronic portal imaging device (EPID) has been developed using Geant4 and its performance for imaging and dosimetry applications in radiotherapy has been characterised. The EPID geometry is based on a physical prototype under ongoing investigation and comprises an array of plastic scin...

journal_title：Physics in medicine and biology

authors： Blake SJ,McNamara AL,Vial P,Holloway L,Kuncic Z

更新日期：2014-11-21 00:00:00

abstract：:By analyzing the radiobiological model, and the equations derived from the model, it is shown that the main results of the article 'The influence of dose heterogeneity on tumor control probability in fractionated radiation therapy' by Wiklund et al (2011 Phys. Med. Biol. 56 7585-600) are valid only under the condition...

journal_title：Physics in medicine and biology

authors： Grusell E

更新日期：2013-09-21 00:00:00

abstract：:To achieve accurate and fast deformable image registration (DIR) for pulmonary CT, we proposed a Multi-scale DIR framework with unsupervised Joint training of Convolutional Neural Network (MJ-CNN). MJ-CNN contains three models at multi-scale levels for a coarse-to-fine DIR to avoid being trapped in a local minimum. It...

journal_title：Physics in medicine and biology

authors： Jiang Z,Yin FF,Ge Y,Ren L

更新日期：2020-01-13 00:00:00

abstract：:The accurate determination of mean ionization potential (I m) has the potential to reduce range uncertainty based margins and therefore allow for more focal treatments in proton radiotherapy. Many methods have been proposed to reduce uncertainty in I m and stopping power ratios (SPR), each with varying degrees of accu...

journal_title：Physics in medicine and biology

authors： Sudhyadhom A

更新日期：2017-10-27 00:00:00

abstract：:The formulation of intensity modulated radiation therapy (IMRT) planning aspects frequently uses the dose-volume histogram (DVH), whereas plan computations often happen in the more desirable convex IMRT optimization framework. Inspired by a recent publication of Zinchenko et al (2008 Phys. Med. Biol. 53 3231-50), this...

journal_title：Physics in medicine and biology

authors： Kratt K,Scherrer A

更新日期：2009-06-21 00:00:00

abstract：:Range verification is one of the most relevant tasks in ion beam therapy. In the case of carbon ion therapy, positron emission tomography (PET) is the most widely used method for this purpose, which images the [Formula: see text]-activation following nuclear interactions of the ions with the tissue nuclei. Since the p...

journal_title：Physics in medicine and biology

authors： Hofmann T,Fochi A,Parodi K,Pinto M

更新日期：2019-05-21 00:00:00