Implementation and analysis of relief patterns of the surface of benign and malignant lesions of the skin by microtopography.

Abstract:

:The objective of this study was to be able to distinguish between healthy skin tissue and malignant ones, furthermore determining a unique pattern of roughness for each skin lesion by microtopographic analysis of the skin surface of Mexican patients during the period from April to October 2002. The standard technique used in this study for the diagnosis of skin cancer and the comparison of the results was the haematoxylin-eosin histopathological technique. Latex impressions were taken from skin lesions as well as from the healthy skin of each patient to serve as control samples. These impressions were analysed by the MICROTOP.03.MFC microtopographic system inspection. It was observed that when the tumour becomes rougher, more malign will be the lesion. On average, the melanoma present an increase of roughness of 67% compared to healthy skin, obtaining a roughness relation of 1:2.54. The percentage decreases to 49% (49%, 1:60) in the case of basal cell carcinoma and to 40% in pre-malignant lesions such as melanocytic nevus (40%, 1:150). In benign lesions such as the seborrhoea keratosis only a small increase in roughness was noted (4%, 1:0.72). Microtopographic inspection of the skin surface can be considered as a complementary diagnostic technique for skin cancer.

journal_name

Phys Med Biol

authors

del Carmen López Pacheco M,da Cunha Martins-Costa MF,Zapata AJ,Cherit JD,Gallegos ER

doi

10.1088/0031-9155/50/23/008

subject

Has Abstract

pub_date

2005-12-07 00:00:00

pages

5535-43

issue

23

eissn

0031-9155

issn

1361-6560

pii

S0031-9155(05)00752-9

journal_volume

50

pub_type

杂志文章
  • Dose effect of guidewire position in intravascular brachytherapy.

    abstract::It has been reported that the dose effects of metallic guidewires are significant in intravascular brachytherapy (IVBT) using a beta source. The purpose of this work is to investigate the dependence of these dose effects on guidewire position. The EGS4 Monte Carlo codes were used to perform the dose calculations for t...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/47/10/309

    authors: Shih R,Hsu WL,Li XA

    更新日期:2002-05-21 00:00:00

  • SpekCalc: a program to calculate photon spectra from tungsten anode x-ray tubes.

    abstract::A software program, SpekCalc, is presented for the calculation of x-ray spectra from tungsten anode x-ray tubes. SpekCalc was designed primarily for use in a medical physics context, for both research and education purposes, but may also be of interest to those working with x-ray tubes in industry. Noteworthy is the p...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/54/19/N01

    authors: Poludniowski G,Landry G,DeBlois F,Evans PM,Verhaegen F

    更新日期:2009-10-07 00:00:00

  • Low-dose 4D cardiac imaging in small animals using dual source micro-CT.

    abstract::Micro-CT is widely used in preclinical studies, generating substantial interest in extending its capabilities in functional imaging applications such as blood perfusion and cardiac function. However, imaging cardiac structure and function in mice is challenging due to their small size and rapid heart rate. To overcome...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa9b45

    authors: Holbrook M,Clark DP,Badea CT

    更新日期:2018-01-09 00:00:00

  • Dual energy x-ray laser measurement of calcaneal bone mineral density.

    abstract::In dual energy x-ray absorptiometry (DXA) the photon attenuation is assumed to be similar in soft tissue overlying, adjacent to and inside the measured bone. In the calcaneal dual energy x-ray laser (DXL) technique, this assumption is not needed as attenuation by soft tissues at the local bone site is determined by co...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/48/12/305

    authors: Hakulinen MA,Saarakkala S,Töyräs J,Kröger H,Jurvelin JS

    更新日期:2003-06-21 00:00:00

  • Image-based view-angle independent cardiorespiratory motion gating and coronary sinus catheter tracking for x-ray-guided cardiac electrophysiology procedures.

    abstract::Determination of the cardiorespiratory phase of the heart has numerous applications during cardiac imaging. In this article we propose a novel view-angle independent near-real time cardiorespiratory motion gating and coronary sinus (CS) catheter tracking technique for x-ray fluoroscopy images that are used to guide ca...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/20/8087

    authors: Panayiotou M,Rhode KS,King AP,Ma Y,Cooklin M,O'Neill M,Gill J,Rinaldi CA,Housden RJ

    更新日期:2015-10-21 00:00:00

  • The investigation of different cameras for in-beam PET imaging.

    abstract::In situ and in vivo treatment plan verification and beam monitoring as well as dose control during heavy-ion tumour therapy can be performed in principle by measurements of range distributions of beta(+)-emitting nuclei by means of PET techniques. For this purpose the performance of different types of positron camera ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/41/2/006

    authors: Pawelke J,Byars L,Enghardt W,Fromm WD,Geissel H,Hasch BG,Lauckner K,Manfrass P,Schardt D,Sobiella M

    更新日期:1996-02-01 00:00:00

  • Classification of movement intention by spatially filtered electromagnetic inverse solutions.

    abstract::We couple standardized low-resolution electromagnetic tomography, an inverse solution for electroencephalography (EEG) and the common spatial pattern, which is here conceived as a data-driven beamformer, to classify the benchmark BCI (brain-computer interface) competition 2003, data set IV. The data set is from an exp...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/51/8/002

    authors: Congedo M,Lotte F,Lécuyer A

    更新日期:2006-04-21 00:00:00

  • Image-guidance for surgical procedures.

    abstract::Contemporary imaging modalities can now provide the surgeon with high quality three- and four-dimensional images depicting not only normal anatomy and pathology, but also vascularity and function. A key component of image-guided surgery (IGS) is the ability to register multi-modal pre-operative images to each other an...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1088/0031-9155/51/14/R01

    authors: Peters TM

    更新日期:2006-07-21 00:00:00

  • Automatic extraction of pectoral muscle in the MLO view of mammograms.

    abstract::A mammogram is the standard modality used for breast cancer screening. Computer-aided detection (CAD) approaches are helpful for improving breast cancer detection rates when applied to mammograms. However, automated analysis of a mammogram often leads to inaccurate results in the presence of the pectoral muscle. There...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/58/23/8493

    authors: Feudjio CK,Klein J,Tiedeu A,Colot O

    更新日期:2013-12-07 00:00:00

  • A Monte Carlo investigation of contaminant electrons due to a novel in vivo transmission detector.

    abstract::A novel transmission detector (IBA Dosimetry, Germany) developed as an IMRT quality assurance tool, intended for in vivo patient dose measurements, is studied here. The goal of this investigation is to use Monte Carlo techniques to characterize treatment beam parameters in the presence of the detector and to compare t...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/56/4/020

    authors: Asuni G,Jensen JM,McCurdy BM

    更新日期:2011-02-21 00:00:00

  • Microwave tomography for functional imaging of extremity soft tissues: feasibility assessment.

    abstract::It is important to assess the viability of extremity soft tissues, as this component is often the determinant of the final outcome of fracture treatment. Microwave tomography (MWT) and sensing might be able to provide a fast and mobile assessment of such properties. MWT imaging of extremities possesses a complicated, ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/52/18/015

    authors: Semenov S,Kellam J,Althausen P,Williams T,Abubakar A,Bulyshev A,Sizov Y

    更新日期:2007-09-21 00:00:00

  • An estimation of noise levels in HMPAO RCBF SPECT images using simulation and phantom data; comparison with results obtained from repeated normal controls.

    abstract::The purpose of this work was to determine noise levels in HMPAO RCBF SPECT images. Eight simulated images of a uniform sphere of activity were made at each of three different count levels. Three images of the Amersham brain phantom were obtained at each of three count levels, roughly corresponding to the simulation le...

    journal_title:Physics in medicine and biology

    pub_type: 临床试验,杂志文章

    doi:10.1088/0031-9155/39/5/006

    authors: Houston AS,Kemp PM,Griffiths PT,MacLeod MA

    更新日期:1994-05-01 00:00:00

  • Algorithm-enabled exploration of image-quality potential of cone-beam CT in image-guided radiation therapy.

    abstract::Kilo-voltage (KV) cone-beam computed tomography (CBCT) unit mounted onto a linear accelerator treatment system, often referred to as on-board imager (OBI), plays an increasingly important role in image-guided radiation therapy. While the FDK algorithm is currently used for reconstructing images from clinical OBI data,...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/12/4601

    authors: Han X,Pearson E,Pelizzari C,Al-Hallaq H,Sidky EY,Bian J,Pan X

    更新日期:2015-06-21 00:00:00

  • Strategies to improve 3D whole-body PET image reconstruction.

    abstract::An algorithm is described for three-dimensional whole-body (3DWB) image reconstruction in positron emission tomography. For whole-body applications, improvements to the popular fixed-axial-acceptance-angle technique are achieved by combining axially adjacent projection data available with a long-axis data set. Time-co...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/41/8/013

    authors: Cutler PD,Xu M

    更新日期:1996-08-01 00:00:00

  • Deformable and durable phantoms with controlled density of scatterers.

    abstract::We have developed deformable and durable optical tissue phantoms with a simple and well-defined microstructure including a novel combination of scatterers and a matrix material. These were developed for speckle and elastography investigations in optical coherence tomography, but should prove useful in many other field...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/53/13/N01

    authors: Bisaillon CE,Lamouche G,Maciejko R,Dufour M,Monchalin JP

    更新日期:2008-07-07 00:00:00

  • Low-frequency conductivity tensor imaging with a single current injection using DT-MREIT.

    abstract::Diffusion tensor - magnetic resonance electrical impedance tomography (DT-MREIT) is an imaging modality to obtain low-frequency anisotropic conductivity distribution employing diffusion tensor imaging (DTI) and magnetic resonance electrical impedance tomography (MREIT) techniques. DT-MREIT is based on the linear relat...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/abddcf

    authors: Sadighi M,Sisman M,Acikgoz BC,Eroglu HH,Eyuboglu BM

    更新日期:2021-01-20 00:00:00

  • Error propagation in quantitative biplane cineroentgenography.

    abstract::The propagation of errors in quantitative biplane cineroentgenography was investigated to see which variables were the most critical. The analysis was carried out both for the propagation of root-mean-square errors and for errors as derived by a Taylor expansion of the reconstruction equations. The reconstruction is m...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/23/4/009

    authors: Smith WM,Starmer CF

    更新日期:1978-07-01 00:00:00

  • Commissioning of pencil beam and Monte Carlo dose engines for non-isocentric treatments in scanned proton beam therapy.

    abstract::This work describes the dosimetric commissioning of the treatment planning system (TPS) RayStation v6.1 from RaySearch Laboratories (Stockholm, Sweden) for a synchrotron-based scanned proton beam delivery with isocentric and non-isocentric setups at MedAustron. Focus was on the comparison of the pencil beam (PBv4.1) a...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab3557

    authors: Carlino A,Böhlen T,Vatnitsky S,Grevillot L,Osorio J,Dreindl R,Palmans H,Stock M,Kragl G

    更新日期:2019-08-28 00:00:00

  • The assessment of the non-equilibrium effect in the 'Patlak analysis' of Fdopa PET studies.

    abstract::'Patlak analysis' is a common approach used in Fdopa PET studies to calculate the uptake constant (Ki) of the tracer. It is assumed in the Patlak analysis that the reversible compartment of tissue radioactivity used is in effective equilibrium with the tracer in plasma. Therefore, using the data prior to equilibrium i...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/40/7/007

    authors: Yu DC,Huang SC,Barrio JR,Phelps ME

    更新日期:1995-07-01 00:00:00

  • Block matching 3D random noise filtering for absorption optical projection tomography.

    abstract::Absorption and emission optical projection tomography (OPT), alternatively referred to as optical computed tomography (optical-CT) and optical-emission computed tomography (optical-ECT), are recently developed three-dimensional imaging techniques with value for developmental biology and ex vivo gene expression studies...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/55/18/009

    authors: Fumene Feruglio P,Vinegoni C,Gros J,Sbarbati A,Weissleder R

    更新日期:2010-09-21 00:00:00

  • Cadmium in man measured in vivo by x-ray fluorescence analysis.

    abstract::The sensitivity and detection limit for measurements of the concentration of cadmium in the kidney cortex of man in vivo have been investigated using the technique of X-ray fluorescence. An 11 GB1 241Am source was used to generate the characteristic K alpha X-rays of cadmium. The variation in the sensitivity for the d...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/26/1/004

    authors: Ahlgren L,Mattsson S

    更新日期:1981-01-01 00:00:00

  • Dynamics of the upper urinary tract: I. Peristaltic flow through a distensible tube of limited length.

    abstract::A theoretical analysis and numerical solutions are presented for viscosity-dominated flow through a uniform, highly distensible tube with a slit-shaped cross section undergoing peristalsis. At flow rates below an intrinsic upper limit to the peristaltic carrying capacity of the tube, provided that there is always at l...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/32/7/002

    authors: Griffiths DJ

    更新日期:1987-07-01 00:00:00

  • Detection of temperature distribution via recovering electrical conductivity in MREIT.

    abstract::In radiofrequency (RF) ablation or hyperthermia, internal temperature measurements and tissue property imaging are important to control their outputs and assess the treatment effect. Recently, magnetic resonance electrical impedance tomography (MREIT), as a non-invasive imaging method of internal conductivity distribu...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/58/8/2697

    authors: Oh TI,Kim HJ,Jeong WC,Chauhan M,Kwon OI,Woo EJ

    更新日期:2013-04-21 00:00:00

  • Automated 3D ultrasound image analysis for first trimester assessment of fetal health.

    abstract::The first trimester fetal ultrasound scan is important to confirm fetal viability, to estimate the gestational age of the fetus, and to detect fetal anomalies early in pregnancy. First trimester ultrasound images have a different appearance than for the second trimester scan, reflecting the different stage of fetal de...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab3ad1

    authors: Ryou H,Yaqub M,Cavallaro A,Papageorghiou AT,Alison Noble J

    更新日期:2019-09-17 00:00:00

  • Quenching-free fluorescence signal from plastic-fibres in proton dosimetry: understanding the influence of Čerenkov radiation.

    abstract::The origin of photons emitted in optical fibres under proton irradiation has been attributed to either entirely Čerenkov radiation or light consisting of fluorescence with a substantial amount of Čerenkov radiation. The source of the light emission is assessed in order to understand why the signal from optical fibres ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aaafad

    authors: Brage Christensen J,Almhagen E,Nyström H,Andersen CE

    更新日期:2018-03-09 00:00:00

  • Monte Carlo- versus pencil-beam-/collapsed-cone-dose calculation in a heterogeneous multi-layer phantom.

    abstract::The aim of this work was to evaluate the accuracy of dose predicted in heterogeneous media by a pencil beam (PB), a collapsed cone (CC) and a Monte Carlo (MC) algorithm. For this purpose, a simple multi-layer phantom composed of Styrofoam and white polystyrene was irradiated with 10 x 10 cm2 as well as 20 x 20 cm2 ope...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/50/5/010

    authors: Krieger T,Sauer OA

    更新日期:2005-03-07 00:00:00

  • Characterization of optical parameters with a human forearm at the region from 1.15 to 1.52 microm using diffuse reflectance measurements.

    abstract::Time- and space-resolved diffuse reflectance measurements were used to identify the optical parameters, the reduced scattering and absorption coefficients, of bulk living tissue in the region from 1.15 to 1.52 microm. Although in this region the detector was limited in its temporal resolution, we applied a peak-time s...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/51/11/021

    authors: Nishimura G,Kida I,Tamura M

    更新日期:2006-06-07 00:00:00

  • Comparison between the lateral penumbra of a collimated double-scattered beam and uncollimated scanning beam in proton radiotherapy.

    abstract::Intensity modulated proton radiotherapy (IMPT) can reduce the dose to critical structures by optimizing the distribution and intensity of individual pencil beams. The IMPT can be delivered by dynamically scanning a pencil beam with variable intensity and energy across the tumor target volume. The lateral penumbra of a...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/53/6/016

    authors: Safai S,Bortfeld T,Engelsman M

    更新日期:2008-03-21 00:00:00

  • Ionization chamber correction factors for MR-linacs.

    abstract::Previously, readings of air-filled ionization chambers have been described as being influenced by magnetic fields. To use these chambers for dosimetry in magnetic resonance guided radiotherapy (MRgRT), this effect must be taken into account by introducing a correction factor k B. The purpose of this study is to system...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aac4f2

    authors: Pojtinger S,Dohm OS,Kapsch RP,Thorwarth D

    更新日期:2018-06-07 00:00:00

  • MR-compatibility assessment of MADPET4: a study of interferences between an SiPM-based PET insert and a 7 T MRI system.

    abstract::Compromises in the design of a positron emission tomography (PET) insert for a magnetic resonance imaging (MRI) system should minimize the deterioration of image quality in both modalities, particularly when simultaneous demanding acquisitions are performed. In this work, the advantages of using individually read-out ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aab9d1

    authors: Omidvari N,Topping G,Cabello J,Paul S,Schwaiger M,Ziegler SI

    更新日期:2018-05-01 00:00:00