Characterization of optical parameters with a human forearm at the region from 1.15 to 1.52 microm using diffuse reflectance measurements.

Abstract:

:Time- and space-resolved diffuse reflectance measurements were used to identify the optical parameters, the reduced scattering and absorption coefficients, of bulk living tissue in the region from 1.15 to 1.52 microm. Although in this region the detector was limited in its temporal resolution, we applied a peak-time shift analysis successfully to determine these coefficients in a human forearm, and then determined the absorption spectrum by space-resolved diffuse reflectance measurements. The absorption spectrum of a water content of 52% determined by magnetic resonance imaging experiments is in good agreement with the absorption coefficient obtained by optical measurements. Moreover, magnetic resonance imaging measurements suggest that the deviation of the absorption coefficients from the water spectrum in the strong water absorption band is caused by the heterogeneity of water distribution in tissue: the low content of water in the skin. These findings indicate that this optical method is potentially applicable to the non-invasive measurement of water in tissue, especially in a region lower than about 1.3-1.35 microm, which may be useful in monitoring oedema and tissue swelling.

journal_name

Phys Med Biol

authors

Nishimura G,Kida I,Tamura M

doi

10.1088/0031-9155/51/11/021

subject

Has Abstract

pub_date

2006-06-07 00:00:00

pages

2997-3011

issue

11

eissn

0031-9155

issn

1361-6560

pii

S0031-9155(06)15489-5

journal_volume

51

pub_type

杂志文章
  • Particle beam microstructure reconstruction and coincidence discrimination in PET monitoring for hadron therapy.

    abstract::Positron emission tomography is one of the most mature techniques for monitoring the particles range in hadron therapy, aiming to reduce treatment uncertainties and therefore the extent of safety margins in the treatment plan. In-beam PET monitoring has been already performed using inter-spill and post-irradiation dat...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aafa28

    authors: Kostara E,Sportelli G,Belcari N,Camarlinghi N,Cerello P,Del Guerra A,Ferrero V,Fiorina E,Giraudo G,Morrocchi M,Pennazio F,Pullia M,Rivetti A,Rolo MD,Rosso V,Wheadon R,Bisogni MG

    更新日期:2019-01-21 00:00:00

  • A potential method for in vivo range verification in proton therapy treatment.

    abstract::Proton therapy potentially offers excellent dose conformality and reduction in integral dose. The superior dose distribution is, however, much more sensitive to the radiological depth along the beam path than for photon fields. Variations in this depth due to inaccurate planning calculation, setup uncertainty, respira...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/53/5/016

    authors: Lu HM

    更新日期:2008-03-07 00:00:00

  • Investigation of the performance of antiscatter grids: Monte Carlo simulation studies.

    abstract::Monte Carlo methods have been applied to the study of the performance of antiscatter grids in radiography. Photon histories for imaging with a 20 cm thick water phantom irradiated with an 80 kV x-ray spectrum were generated by Monte Carlo simulation. The scattering and absorption of the photons transmitted from the ph...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/27/6/002

    authors: Chan HP,Doi K

    更新日期:1982-06-01 00:00:00

  • A novel geometry-dosimetry label fusion method in multi-atlas segmentation for radiotherapy: a proof-of-concept study.

    abstract::Multi-atlas segmentation (MAS) has been widely used to automate the delineation of organs at risk (OARs) for radiotherapy. Label fusion is a crucial step in MAS to cope with the segmentation variabilities among multiple atlases. However, most existing label fusion methods do not consider the potential dosimetric impac...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa5ed9

    authors: Chang J,Tian Z,Lu W,Gu X,Chen M,Jiang SB

    更新日期:2017-05-07 00:00:00

  • A theoretical comparison of energy sources--microwave, ultrasound and laser--for interstitial thermal therapy.

    abstract::A number of heating sources are available for minimally invasive thermal therapy of tumours. The purpose of this work was to compare, theoretically, the heating characteristics of interstitial microwave, laser and ultrasound sources in three tissue sites: breast, brain and liver. Using a numerical method, the heating ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/43/12/011

    authors: Skinner MG,Iizuka MN,Kolios MC,Sherar MD

    更新日期:1998-12-01 00:00:00

  • Performance of isotropic light dosimetry probes based on scattering bulbs in turbid media.

    abstract::In a previous paper the calibration of an isotropic light detector in clear media was described and validated. However, in most applications the detector is used to measure light distribution in turbid (scattering) media, that is, in tissues or tissue equivalent optical phantoms. Despite its small diameter (typically ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/47/12/304

    authors: Marijnissen JP,Star WM

    更新日期:2002-06-21 00:00:00

  • In vivo evaluation of a new system for 3D computerized angiography.

    abstract::A new system has been designed and built to validate the concept of 3D computerized angiography (CA). This system can acquire a set of 2D digital subtracted angiography images while rotating around a patient and then, using these images, reconstruct a 3D representation of the opacified vasculature. The design principl...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/39/3/020

    authors: Saint-Félix D,Trousset Y,Picard C,Ponchut C,Roméas R,Rougée A

    更新日期:1994-03-01 00:00:00

  • Four-dimensional Monte Carlo simulation of time-dependent geometries.

    abstract::Dynamic radiation therapy techniques require that the treatment head setup varies in time and space during dose delivery. Examples are leaf motion in intensity modulated x-ray therapy, modulator wheel rotation in conventional proton therapy and variable magnet settings in proton beam scanning. Consequently, for Monte ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/49/6/n03

    authors: Paganetti H

    更新日期:2004-03-21 00:00:00

  • The physics of red cell sedimentation.

    abstract::Blood was withdrawn from the ante-cubital vein of five normal volunteers and the erythrocytes were washed and resuspended in isotonic saline. The rate of descent of the erythrocyte-saline boundary was measured every hour for a period of at least 4 h for different suspended cell concentrations. The velocity of this bou...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/30/2/002

    authors: Smallwood RH,Tindale WB,Trowbridge EA

    更新日期:1985-02-01 00:00:00

  • Monte Carlo-based evaluation of S-values in mouse models for positron-emitting radionuclides.

    abstract::In addition to being a powerful clinical tool, Positron emission tomography (PET) is also used in small laboratory animal research to visualize and track certain molecular processes associated with diseases such as cancer, heart disease and neurological disorders in living small animal models of disease. However, dosi...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/58/1/169

    authors: Xie T,Zaidi H

    更新日期:2013-01-07 00:00:00

  • Simulation study to improve the performance of a whole-body PbF2 Cherenkov TOF-PET scanner.

    abstract::Using Cherenkov radiation in positron emission tomography (PET) has the potential to improve the time of flight (TOF) resolution and reduce the cost of detectors. In previous studies promising TOF results were achieved when lead fluoride (PbF2) crystals were used instead of a scintillator. In this work, a whole-body P...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab6f97

    authors: Consuegra D,Korpar S,Križan P,Pestotnik R,Razdevšek G,Dolenec R

    更新日期:2020-03-06 00:00:00

  • EPR dosimetry of radiotherapy photon beams in inhomogeneous media using alanine films.

    abstract::In the current work, EPR (electron paramagnetic resonance) dosimetry using alanine films (134 microm thick) was utilized for dose measurements in inhomogeneous phantoms irradiated with radiotherapy photon beams. The main phantom material was PMMA, while either Styrofoam or aluminium was introduced as an inhomogeneity....

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/51/24/003

    authors: Osterås BH,Hole EO,Olsen DR,Malinen E

    更新日期:2006-12-21 00:00:00

  • A flat-panel detector based micro-CT system: performance evaluation for small-animal imaging.

    abstract::A dedicated small-animal x-ray micro computed tomography (micro-CT) system has been developed to screen laboratory small animals such as mice and rats. The micro-CT system consists of an indirect-detection flat-panel x-ray detector with a field-of-view of 120 x 120 mm2, a microfocus x-ray source, a rotational subject ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/48/24/014

    authors: Lee SC,Kim HK,Chun IK,Cho MH,Lee SY,Cho MH

    更新日期:2003-12-21 00:00:00

  • A multiplicative correction factor for tissue heterogeneities.

    abstract::A new multiplicative correction factor for tissue heterogeneities based on an exact expression for homogeneous non-unit-density media is proposed. O'Connor's density scaling theorem is invoked to evaluate the medium-specific tissue-maximum ratios used in the exact formulation. Monte Carlo calculations were performed a...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/31/10/005

    authors: Petti PL,Siddon RL,Bjärngard BE

    更新日期:1986-10-01 00:00:00

  • Treatment plan modification using voxel-based weighting factors/dose prescription.

    abstract::Under various clinical situations, it is desirable to modify the original treatment plan to better suit the clinical goals. In this work, a method to help physicians modify treatment plans based on their clinical preferences is proposed. The method uses a weighted quadratic dose objective function. The commonly used o...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/48/15/315

    authors: Wu C,Olivera GH,Jeraj R,Keller H,Mackie TR

    更新日期:2003-08-07 00:00:00

  • Development of 4D mathematical observer models for the task-based evaluation of gated myocardial perfusion SPECT.

    abstract::This paper presents two 4D mathematical observer models for the detection of motion defects in 4D gated medical images. Their performance was compared with results from human observers in detecting a regional motion abnormality in simulated 4D gated myocardial perfusion (MP) SPECT images. The first 4D mathematical obs...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/7/2751

    authors: Lee TS,Frey EC,Tsui BM

    更新日期:2015-04-07 00:00:00

  • Evaluation of high performance data acquisition boards for simultaneous sampling of fast signals from PET detectors.

    abstract::Detectors used for positron emission tomography (PET) provide fast, randomly distributed signals that need to be digitized for further processing. One possibility is to sample the signals at the peak initiated by a trigger from a constant fraction discriminator (CFD). For PET detectors, simultaneous acquisition of man...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/50/1/003

    authors: Judenhofer MS,Pichler BJ,Cherry SR

    更新日期:2005-01-07 00:00:00

  • The exponential edge-gradient effect in x-ray computed tomography.

    abstract::The exponential edge-gradient effect must arise in any x-ray transmission CT scanner whenever long sharp edges of high contrast are encountered. The effect is non-linear and is due to the interaction of the exponential law of x-ray attenuation and the finite width of the scanning beam in the x-y plane. The error induc...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/26/3/010

    authors: Joseph PM,Spital RD

    更新日期:1981-05-01 00:00:00

  • Dynamics of the upper urinary tract: I. Peristaltic flow through a distensible tube of limited length.

    abstract::A theoretical analysis and numerical solutions are presented for viscosity-dominated flow through a uniform, highly distensible tube with a slit-shaped cross section undergoing peristalsis. At flow rates below an intrinsic upper limit to the peristaltic carrying capacity of the tube, provided that there is always at l...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/32/7/002

    authors: Griffiths DJ

    更新日期:1987-07-01 00:00:00

  • Improving mass detection using combined feature representations from projection views and reconstructed volume of DBT and boosting based classification with feature selection.

    abstract::In digital breast tomosynthesis (DBT), image characteristics of projection views and reconstructed volume are different and both have the advantage of detecting breast masses, e.g. reconstructed volume mitigates a tissue overlap, while projection views have less reconstruction blur artifacts. In this paper, an improve...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/22/8809

    authors: Kim DH,Kim ST,Ro YM

    更新日期:2015-11-21 00:00:00

  • The use of tonebursts as an alternative to broadband signals in the measurement of speed of sound in human cancellous bone.

    abstract::Speed of sound (SOS) measurements, typically made using 1 MHz broadband pulses, are increasingly used in the clinical diagnosis of bone disorders. Previous in vitro studies indicate that broadband ultrasound pulses are susceptible to distortion in cancellous bone, leading to imprecise arrival time and SOS measurements...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/45/7/317

    authors: Pollintine P,Haddaway MJ,Davie MW

    更新日期:2000-07-01 00:00:00

  • Pre- and post-natal exposure of children to EMF generated by domestic induction cookers.

    abstract::Induction cookers are a type of cooking appliance that uses an intermediate-frequency magnetic field to heat the cooking vessel. The magnetic flux density produced by an induction cooker during operation was measured according to the EN 62233 standard, and the measured values were below the limits set in the standard....

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/56/19/001

    authors: Kos B,Valič B,Miklavčič D,Kotnik T,Gajšek P

    更新日期:2011-10-07 00:00:00

  • Comparison of Monte Carlo and analytical dose computations for intensity modulated proton therapy.

    abstract::To evaluate the effect of approximations in clinical analytical calculations performed by a treatment planning system (TPS) on dosimetric indices in intensity modulated proton therapy. TPS calculated dose distributions were compared with dose distributions as estimated by Monte Carlo (MC) simulations, calculated with ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aaa845

    authors: Yepes P,Adair A,Grosshans D,Mirkovic D,Poenisch F,Titt U,Wang Q,Mohan R

    更新日期:2018-02-09 00:00:00

  • 4D Monte Carlo simulation of proton beam scanning: modelling of variations in time and space to study the interplay between scanning pattern and time-dependent patient geometry.

    abstract::When dosimetric effects in time-dependent geometries are studied, usually either the results of individual three-dimensional (3D) calculations are combined or probability-based approaches are applied. These methods may become cumbersome and time-consuming if high time resolution is required or if the geometry is compl...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/50/5/020

    authors: Paganetti H,Jiang H,Trofimov A

    更新日期:2005-03-07 00:00:00

  • Lateral variations of radiobiological properties of therapeutic fields of 1H, 4He, 12C and 16O ions studied with Geant4 and microdosimetric kinetic model.

    abstract::As known, in cancer therapy with ion beams the relative biological effectiveness (RBE) of ions changes in the course of their propagation in tissues. Such changes are caused not only by increasing the linear energy transfer (LET) of beam particles with the penetration depth towards the Bragg peak, but also by nuclear ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa75b2

    authors: Dewey S,Burigo L,Pshenichnov I,Mishustin I,Bleicher M

    更新日期:2017-06-27 00:00:00

  • An adaptive technique for digital noise suppression in on-line portal imaging.

    abstract::Two complementary approaches to the noise suppression problem in on-line portal imaging have been analysed. Temporal filtering by image summation can substantially reduce the amount of noise in an image. In many cases, however, movements of the patient or the radiation source limit the time period over which the avera...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/35/3/011

    authors: Leszczynski KW,Shalev S,Cosby NS

    更新日期:1990-03-01 00:00:00

  • The replacement correction factors for cylindrical chambers in high-energy photon beams.

    abstract::The values of the replacement correction factors (P(repl), or in the IAEA's notation p(dis)p(cav)) used for cylindrical chambers in high-energy photon beams represent one of the most significant differences between the AAPM and the IAEA dosimetry protocols. In a previous study (Wang L L W and Rogers D W O 2008 Med. Ph...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/54/6/014

    authors: Wang LL,Rogers DW

    更新日期:2009-03-21 00:00:00

  • In vivo real-time cavitation imaging in moving organs.

    abstract::The stochastic nature of cavitation implies visualization of the cavitation cloud in real-time and in a discriminative manner for the safe use of focused ultrasound therapy. This visualization is sometimes possible with standard echography, but it strongly depends on the quality of the scanner, and is hindered by diff...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa4fe8

    authors: Arnal B,Baranger J,Demene C,Tanter M,Pernot M

    更新日期:2017-02-07 00:00:00

  • A thin target approach for portal imaging in medical accelerators.

    abstract::A new thin-target method (patent pending) is described for portal imaging with low-energy (tens of keV) photons from a medical linear accelerator operating in a special mode. Low-energy photons are usually produced in the accelerator target, but are absorbed by the target and flattening filter, both made of medium- or...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/43/8/016

    authors: Tsechanski A,Bielajew AF,Faermann S,Krutman Y

    更新日期:1998-08-01 00:00:00

  • A method for acquiring random range uncertainty probability distributions in proton therapy.

    abstract::In treatment planning we depend upon accurate knowledge of geometric and range uncertainties. If the uncertainty model is inaccurate then the plan will produce under-dosing of the target and/or overdosing of OAR. We aim to provide a method for which centre and site-specific population range uncertainty due to inter-fr...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa9502

    authors: Holloway SM,Holloway MD,Thomas SJ

    更新日期:2017-12-19 00:00:00