A thin target approach for portal imaging in medical accelerators.

Abstract:

:A new thin-target method (patent pending) is described for portal imaging with low-energy (tens of keV) photons from a medical linear accelerator operating in a special mode. Low-energy photons are usually produced in the accelerator target, but are absorbed by the target and flattening filter, both made of medium- or high-Z materials such as Cu or W. Since the main contributor to absorption of the low-energy photons is self-absorption by the thick target through the photoelectric effect, it is proposed to lower the thickness of the portal imaging target to the minimum required to get the maximum low-energy photon fluence on the exit side of the target, and to lower the atomic number of the target so that predominantly photoelectric absorption is reduced. To determine the minimum thickness of the target, EGS4 Monte Carlo calculations were performed. As a result of these calculations, it was concluded that the maximum photon fluence for a 4 MeV electron beam is obtained with a 1.5 mm Cu target. This value is approximately five times less than the thickness of the Cu target routinely used for bremsstrahlung production in radiotherapeutic practice. Two sets of experiments were performed: the first with a 1.5 mm Cu target and the second with a 5 mm Al target (Cu mass equivalent) installed in the linear accelerator. Portal films were taken with a Rando anthropomorphic phantom. To emphasize the low-energy response of the new thin target we used a Kodak Min-R mammographic film and cassette combination, with a strong low-energy response. Because of its high sensitivity, only 1 cGy is required. The new portal images show a remarkable improvement in sharpness and contrast in anatomical detail compared with existing ones. It is also shown that further lowering of the target's atomic number (for example to C or Be) produces no significant improvement.

journal_name

Phys Med Biol

authors

Tsechanski A,Bielajew AF,Faermann S,Krutman Y

doi

10.1088/0031-9155/43/8/016

subject

Has Abstract

pub_date

1998-08-01 00:00:00

pages

2221-36

issue

8

eissn

0031-9155

issn

1361-6560

journal_volume

43

pub_type

杂志文章
  • Large blood vessel cooling in heated tissues: a numerical study.

    abstract::Large blood vessels can produce steep temperature gradients in heated tissues leading to inadequate tissue temperatures during hyperthermia. This paper utilizes a finite difference scheme to solve the basic equations of heat transfer and fluid flow to model blood vessel cooling. Unlike previous formulations, heat tran...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/40/4/001

    authors: Kolios MC,Sherar MD,Hunt JW

    更新日期:1995-04-01 00:00:00

  • A breathing thorax phantom with independently programmable 6D tumour motion for dosimetric measurements in radiation therapy.

    abstract::Irradiation of moving targets using a scanned ion beam can cause clinically intolerable under- and overdosages within the target volume due to the interplay effect. Several motion mitigation techniques such as gating, beam tracking and rescanning are currently investigated to overcome this restriction. To enable detai...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/57/8/2235

    authors: Steidl P,Richter D,Schuy C,Schubert E,Haberer T,Durante M,Bert C

    更新日期:2012-04-21 00:00:00

  • Stability analysis of a deterministic dose calculation for MRI-guided radiotherapy.

    abstract::Modern effort in radiotherapy to address the challenges of tumor localization and motion has led to the development of MRI guided radiotherapy technologies. Accurate dose calculations must properly account for the effects of the MRI magnetic fields. Previous work has investigated the accuracy of a deterministic linear...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa959a

    authors: Zelyak O,Fallone BG,St-Aubin J

    更新日期:2017-12-14 00:00:00

  • Monte Carlo dosimetric study of the BEBIG Co-60 HDR source.

    abstract::Although not as widespread as Ir-192, Co-60 is also available on afterloading equipment devoted to high dose rate brachytherapy, mainly addressed to the treatment of gynaecological lesions. The purpose of this study is to obtain the dosimetric parameters of the Co-60 source used by the BEBIG MultiSource remote afterlo...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/50/21/N03

    authors: Ballester F,Granero D,Pérez-Calatayud J,Casal E,Agramunt S,Cases R

    更新日期:2005-11-07 00:00:00

  • Mapping initial and general recombination in scanning proton pencil beams.

    abstract::The ion recombination is examined in parallel-plate ionization chambers in scanning proton beams at the Danish Centre for Particle Therapy and the Skandion Clinic. The recombination correction factor k s is investigated for clinically relevant energies between 70 MeV and 244 MeV for dose rates below 400 Gy min-1 in ai...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab8579

    authors: Christensen JB,Almhagen E,Stolarczyk L,Liszka M,Hernandez GG,Bassler N,Nørrevang O,Vestergaard A

    更新日期:2020-06-05 00:00:00

  • Dosimetry of 106Ru eye applicators with a p-type silicon detector.

    abstract::Beta emitting 106Ru-applicators are used to treat choroidal melanoma. In order to improve the accuracy and simplify the dosimetry of these applicators, the suitability of using a p-type silicon semiconductor detector has been investigated. The detector is calibrated in a low energy electron beam. An important property...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/36/7/005

    authors: Lax I

    更新日期:1991-07-01 00:00:00

  • A method for photon beam Monte Carlo multileaf collimator particle transport.

    abstract::Monte Carlo (MC) algorithms are recognized as the most accurate methodology for patient dose assessment. For intensity-modulated radiation therapy (IMRT) delivered with dynamic multileaf collimators (DMLCs), accurate dose calculation, even with MC, is challenging. Accurate IMRT MC dose calculations require inclusion o...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/47/17/312

    authors: Siebers JV,Keall PJ,Kim JO,Mohan R

    更新日期:2002-09-07 00:00:00

  • Fully 3D iterative scatter-corrected OSEM for HRRT PET using a GPU.

    abstract::Accurate scatter correction is especially important for high-resolution 3D positron emission tomographies (PETs) such as high-resolution research tomograph (HRRT) due to large scatter fraction in the data. To address this problem, a fully 3D iterative scatter-corrected ordered subset expectation maximization (OSEM) in...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/56/15/021

    authors: Kim KS,Ye JC

    更新日期:2011-08-07 00:00:00

  • Dielectric properties of porcine glands, gonads and body fluids.

    abstract::Dielectric properties of porcine glandular tissues and gonads (in vivo) and body fluids (in vitro) have been obtained in the frequency range of 50 MHz to 20 GHz. The experimental data were fitted to a two term Cole-Cole expression. The data presented complement the available dielectric properties of tissues in the lit...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/57/19/N339

    authors: Peyman A,Gabriel C

    更新日期:2012-10-07 00:00:00

  • Segmentation of dynamic PET images with kinetic spectral clustering.

    abstract::Segmentation is often required for the analysis of dynamic positron emission tomography (PET) images. However, noise and low spatial resolution make it a difficult task and several supervised and unsupervised methods have been proposed in the literature to perform the segmentation based on semi-automatic clustering of...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/58/19/6931

    authors: Mouysset S,Zbib H,Stute S,Girault JM,Charara J,Noailles J,Chalon S,Buvat I,Tauber C

    更新日期:2013-10-07 00:00:00

  • Internal dosimetry with the Monte Carlo code GATE: validation using the ICRP/ICRU female reference computational model.

    abstract::The purpose of this work was to validate GATE-based clinical scale absorbed dose calculations in nuclear medicine dosimetry. GATE (version 6.2) and MCNPX (version 2.7.a) were used to derive dosimetric parameters (absorbed fractions, specific absorbed fractions and S-values) for the reference female computational model...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/62/5/1885

    authors: Villoing D,Marcatili S,Garcia MP,Bardiès M

    更新日期:2017-03-07 00:00:00

  • Polaroid-PET: a PET scanner with detectors fitted with Polaroid for filtering unpolarized optical photons-a Monte Carlo simulation study.

    abstract::We propose and evaluate the performance of an improved preclinical positron emission tomography (PET) scanner design, referred to as Polaroid-PET, consisting of a detector equipped with a layer of horizontal Polaroid to filter scintillation photons with vertical polarization. This makes it possible to improve the spat...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/abaeb8

    authors: Sanaat A,Ashrafi-Belgabad A,Zaidi H

    更新日期:2020-12-02 00:00:00

  • Evaluation of multiple-sphere head models for MEG source localization.

    abstract::Magnetoencephalography (MEG) source analysis has largely relied on spherical conductor models of the head to simplify forward calculations of the brain's magnetic field. Multiple- (or overlapping, local) sphere models, where an optimal sphere is selected for each sensor, are considered an improvement over single-spher...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/56/17/010

    authors: Lalancette M,Quraan M,Cheyne D

    更新日期:2011-09-07 00:00:00

  • Estimation of mean glandular dose for breast tomosynthesis: factors for use with the UK, European and IAEA breast dosimetry protocols.

    abstract::A formalism is proposed for the estimation of mean glandular dose for breast tomosynthesis, which is a simple extension of the UK, European and IAEA protocols for dosimetry in conventional projection mammography. The formalism introduces t-factors for the calculation of breast dose from a single projection and T-facto...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/56/2/011

    authors: Dance DR,Young KC,van Engen RE

    更新日期:2011-01-21 00:00:00

  • Tomographic sensing and localization of fluorescently labeled circulating cells in mice in vivo.

    abstract::Sensing and enumeration of specific types of circulating cells in small animals is an important problem in many areas of biomedical research. Microscopy-based fluorescence in vivo flow cytometry methods have been developed previously, but these are typically limited to sampling of very small blood volumes, so that ver...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/57/14/4627

    authors: Zettergren E,Swamy T,Runnels J,Lin CP,Niedre M

    更新日期:2012-07-21 00:00:00

  • Prior image constrained scatter correction in cone-beam computed tomography image-guided radiation therapy.

    abstract::X-ray scatter is a significant problem in cone-beam computed tomography when thicker objects and larger cone angles are used, as scattered radiation can lead to reduced contrast and CT number inaccuracy. Advances have been made in x-ray computed tomography (CT) by incorporating a high quality prior image into the imag...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/56/4/009

    authors: Brunner S,Nett BE,Tolakanahalli R,Chen GH

    更新日期:2011-02-21 00:00:00

  • Modelling of electron contamination in clinical photon beams for Monte Carlo dose calculation.

    abstract::The purpose of this work is to model electron contamination in clinical photon beams and to commission the source model using measured data for Monte Carlo treatment planning. In this work, a planar source is used to represent the contaminant electrons at a plane above the upper jaws. The source size depends on the di...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/49/12/013

    authors: Yang J,Li JS,Qin L,Xiong W,Ma CM

    更新日期:2004-06-21 00:00:00

  • SAR variation study from 300 to 5000 MHz for 15 voxel models including different postures.

    abstract::An extensive study on specific absorption rate (SAR) covering 720 simulations and 15 voxel models (18-105 kg) has been performed by applying the parallel finite-difference time-domain method. High-resolution whole-body models have been irradiated with plane waves from 300 MHz to 5 GHz by applying various incoming dire...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/55/4/017

    authors: Uusitupa T,Laakso I,Ilvonen S,Nikoskinen K

    更新日期:2010-02-21 00:00:00

  • Carbon dioxide reactivity of computed tomography functional parameters in rabbit VX2 soft tissue tumour.

    abstract::Tumour blood flow is one of the important factors limiting the efficacy of radiation therapy (hypoxic radioresistance), chemotherapy (drug delivery) and thermal therapy (heat dissipation) in treating cancer. The modification of tumour blood flow has been an area of intense investigation. In the current study, the arte...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/48/7/303

    authors: Purdie TG,Lee TY

    更新日期:2003-04-07 00:00:00

  • Quantitative analysis of synchrotron radiation intravenous angiographic images.

    abstract::A medical research protocol on clinical intravenous coronary angiography has been completed at the European Synchrotron Radiation Facility (ESRF) biomedical beamline. The aim was to investigate the accuracy of intravenous coronary angiography based on the K-edge digital subtraction technique for the detection of in-st...

    journal_title:Physics in medicine and biology

    pub_type: 临床试验,杂志文章

    doi:10.1088/0031-9155/50/4/011

    authors: Sarnelli A,Nemoz C,Elleaume H,Estève F,Bertrand B,Bravin A

    更新日期:2005-02-21 00:00:00

  • A new optimal wavelength for treatment of port wine stains?

    abstract::In this study we investigate light penetration into skin in order to define the optimal wavelength for the treatment of port wine stains. A two-layer model (epidermis and dermis) is applied with a cylindric tube representing the ectatic blood vessel. Light propagation is calculated by the Monte Carlo method. Values fo...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/40/10/001

    authors: Kienle A,Hibst R

    更新日期:1995-10-01 00:00:00

  • Development of 4D mathematical observer models for the task-based evaluation of gated myocardial perfusion SPECT.

    abstract::This paper presents two 4D mathematical observer models for the detection of motion defects in 4D gated medical images. Their performance was compared with results from human observers in detecting a regional motion abnormality in simulated 4D gated myocardial perfusion (MP) SPECT images. The first 4D mathematical obs...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/7/2751

    authors: Lee TS,Frey EC,Tsui BM

    更新日期:2015-04-07 00:00:00

  • Simultaneous EEG-fMRI: evaluating the effect of the cabling configuration on the gradient artefact.

    abstract::EEG recordings made in combined EEG-fMRI studies are corrupted by gradient artefacts (GAs) resulting from the interaction of the EEG system with the time-varying magnetic field gradients used in MRI. The dominant contribution to the GA arises from interaction with the leads of the EEG cap and the human head, but artef...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/12/N241

    authors: Chowdhury ME,Mullinger KJ,Bowtell R

    更新日期:2015-06-21 00:00:00

  • Is it necessary to plan with safety margins for actively scanned proton therapy?

    abstract::In radiation therapy, a plan is robust if the calculated and the delivered dose are in agreement, even in the case of different uncertainties. The current practice is to use safety margins, expanding the clinical target volume sufficiently enough to account for treatment uncertainties. This, however, might not be idea...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/56/14/011

    authors: Albertini F,Hug EB,Lomax AJ

    更新日期:2011-07-21 00:00:00

  • A mathematical model of the biologically effective dose of solar UVA received by patients undergoing oral psoralen photochemotherapy for psoriasis.

    abstract::A theoretical analysis is presented of the biologically effective dose of the solar long wave ultraviolet radiation (UVA) received by patients who are being treated for psoriasis by oral psoralen photochemotherapy. It is shown that patients treated during the summer months in the UK may well receive a UV dose which is...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/26/6/011

    authors: Diffey BL

    更新日期:1981-11-01 00:00:00

  • Accurate helical cone-beam CT reconstruction with redundant data.

    abstract::We present a new image reconstruction algorithm for helical cone-beam computed tomography (CT). This algorithm is designed for data collected at or near maximum pitch, and provides a theoretically exact and stable reconstruction while beneficially using all measured data. The main operations involved are a differentia...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/54/15/001

    authors: Schöndube H,Stierstorfer K,Noo F

    更新日期:2009-08-07 00:00:00

  • Implementation of tetrahedral-mesh geometry in Monte Carlo radiation transport code PHITS.

    abstract::A new function to treat tetrahedral-mesh geometry was implemented in the particle and heavy ion transport code systems. To accelerate the computational speed in the transport process, an original algorithm was introduced to initially prepare decomposition maps for the container box of the tetrahedral-mesh geometry. Th...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa6b45

    authors: Furuta T,Sato T,Han MC,Yeom YS,Kim CH,Brown JL,Bolch WE

    更新日期:2017-06-21 00:00:00

  • Role of skin tissue layers and ultra-structure in transcutaneous electrical stimulation including tDCS.

    abstract:BACKGROUND:During transcranial electrical stimulation (tES), including transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS), current density concentration around the electrode edges that is predicted by simplistic skin models does not match experimental observations of ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/abb7c1

    authors: Khadka N,Bikson M

    更新日期:2020-09-11 00:00:00

  • Segmentation and classification of thyroid follicular neoplasm using cascaded convolutional neural network.

    abstract::In this paper, we present a segmentation and classification method for thyroid follicular neoplasms based on a combination of the prior-based level set method and deep convolutional neural network. The proposed method aims to discriminate thyroid follicular adenoma (TFA) and follicular thyroid carcinoma (FTC) in ultra...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/abc6f2

    authors: Yang B,Yan M,Yan Z,Zhu C,Xu D,Dong F

    更新日期:2020-11-02 00:00:00

  • Determination of mean ionization potential using magnetic resonance imaging for the reduction of proton beam range uncertainties: theory and application.

    abstract::The accurate determination of mean ionization potential (I m) has the potential to reduce range uncertainty based margins and therefore allow for more focal treatments in proton radiotherapy. Many methods have been proposed to reduce uncertainty in I m and stopping power ratios (SPR), each with varying degrees of accu...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa8d9e

    authors: Sudhyadhom A

    更新日期:2017-10-27 00:00:00