Abstract:
:Monte Carlo methods have been applied to the study of the performance of antiscatter grids in radiography. Photon histories for imaging with a 20 cm thick water phantom irradiated with an 80 kV x-ray spectrum were generated by Monte Carlo simulation. The scattering and absorption of the photons transmitted from the phantom were traced in the grid. Grids were evaluated with strip densities ranging from 10 to 67 lines/cm, grid ratios from 6 to 15, and lead-to-interspace ratios from 1/9 to 1/2. The contrast improvement factor and the Bucky factor were used as the benefit and cost indicators, respectively, for evaluation of the grids. The dependence of these factors on the grid ratio, lead-to-interspace ratio, strip density, lead content, and interspace material was investigated. The results indicate that high-strip-density grids with thin lead strips and high grid ratios can provide higher contrast improvement factors than are achieved with low-strip-density grids, without an increase in patient exposure. This theoretical approach is useful for the prediction and development of optimal antiscatter grids for radiographic procedures.
journal_name
Phys Med Bioljournal_title
Physics in medicine and biologyauthors
Chan HP,Doi Kdoi
10.1088/0031-9155/27/6/002subject
Has Abstractpub_date
1982-06-01 00:00:00pages
785-803issue
6eissn
0031-9155issn
1361-6560journal_volume
27pub_type
杂志文章abstract::In robotic radiosurgery, it is necessary to compensate for systematic latencies arising from target tracking and mechanical constraints. This compensation is usually achieved by means of an algorithm which computes the future target position. In most scientific works on respiratory motion prediction, only one or two a...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/58/11/3911
更新日期:2013-06-07 00:00:00
abstract::This work investigates the attenuation of a proton beam to reconstruct the map of the linear attenuation coefficient of a material which is mainly caused by the inelastic interactions of protons with matter. Attenuation proton computed tomography (pCT) suffers from a poor spatial resolution due to multiple Coulomb sca...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/61/9/3258
更新日期:2016-05-07 00:00:00
abstract::For renal dynamic studies, the COST B2 hybrid phantom is an example of an artificially created software phantom. Although this phantom is useful, it is not possible to implement the phantom in a self-consistent fashion to produce, for example, a collection of tracer in the bladder which is related to the flow from the...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/44/2/008
更新日期:1999-02-01 00:00:00
abstract::Fractional flow reserve (FFR) provides an objective physiological evaluation of stenosis severity. A technique that can measure FFR using only angiographic images would be a valuable tool in the cardiac catheterization laboratory. To perform this, the diseased blood flow can be measured with a first pass distribution ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/53/14/017
更新日期:2008-07-21 00:00:00
abstract::An optimized configuration of multi-pinhole aperture can improve the spatial resolution and the sensitivity of pinhole SPECT simultaneously. In this study, an optimization strategy of the multi-pinhole configuration with a small detector is proposed for mouse cardiac imaging. A 14 mm-diameter spherical field-of-view (...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/60/2/473
更新日期:2015-01-21 00:00:00
abstract::Accurate scatter correction is especially important for high-resolution 3D positron emission tomographies (PETs) such as high-resolution research tomograph (HRRT) due to large scatter fraction in the data. To address this problem, a fully 3D iterative scatter-corrected ordered subset expectation maximization (OSEM) in...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/56/15/021
更新日期:2011-08-07 00:00:00
abstract::We study the treatment plan optimization problem for volumetric modulated arc therapy (VMAT). We propose a new column-generation-based algorithm that takes into account bounds on the gantry speed and dose rate, as well as an upper bound on the rate of change of the gantry speed, in addition to MLC constraints. The alg...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/57/14/4569
更新日期:2012-07-21 00:00:00
abstract::A system is described in which large superficial areas of tissue may be heated using a single plane ultrasonic transducer scanned in a raster fashion. The shape of the heated area is determined by the movement of a microswitch which is activated when it strikes the rigid edge of a hole of the required shape cut in a p...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/30/12/006
更新日期:1985-12-01 00:00:00
abstract::Using Monte Carlo simulation of 99Tcm single-photon-emission computed tomography (SPECT), we investigate the effects of tissue-background activity, tumour location, patient size, uncertainty of energy windows, and definition of tumour region on the accuracy of quantification. The dual-energy-window method of correctio...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/40/1/015
更新日期:1995-01-01 00:00:00
abstract::A photon diffusion model has been developed to calculate the steady-state spatially resolved fluorescence from pencil beam excitation in layered tissue. The model allows the calculation of both the excitation reflectance and the fluorescence escape for an arbitrary continuous depth distribution of tissue optical prope...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/46/2/307
更新日期:2001-02-01 00:00:00
abstract::In this work we present the first delivery of intensity modulated arc therapy on the Elekta Unity 1.5 T MR-linac. The machine's current IMRT based control system was modified suitably to enable dynamic delivery of radiation, for the purpose of exploring MRI-guided radiation therapy adaptation modes in a research setti...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/1361-6560/abd66d
更新日期:2020-12-23 00:00:00
abstract::The purpose of this work was to determine noise levels in HMPAO RCBF SPECT images. Eight simulated images of a uniform sphere of activity were made at each of three different count levels. Three images of the Amersham brain phantom were obtained at each of three count levels, roughly corresponding to the simulation le...
journal_title:Physics in medicine and biology
pub_type: 临床试验,杂志文章
doi:10.1088/0031-9155/39/5/006
更新日期:1994-05-01 00:00:00
abstract::For angiography using synchrotron radiation we measured the absorbed dose distribution in inhomogeneous phantoms with thin LiF:Mg, Cu, P, LiF:Mg, Ti thermoluminescent dosimeters (TLDs) in tissue and lung substitutes, and with Mg2SiO4:Tb TLDs in bone substitute for 33.32 keV monoenergetic photons from synchrotron radia...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/46/3/308
更新日期:2001-03-01 00:00:00
abstract::Radiobiological models for estimating normal tissue complication probability (NTCP) are increasingly used in order to quantify or optimize the clinical outcome of radiation therapy. A good NTCP model should fulfill at least the following two requirements: (a) it should predict the sigmoid shape of the corresponding do...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/53/22/016
更新日期:2008-11-21 00:00:00
abstract::A clinical trial named PROMETHEUS is currently ongoing for inoperable hepatocellular carcinoma (HCC) at the Heidelberg Ion Beam Therapy Center (HIT, Germany). In this framework, 4D PET-CT datasets are acquired shortly after the therapeutic treatment to compare the irradiation induced PET image with a Monte Carlo PET p...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/61/11/4141
更新日期:2016-06-07 00:00:00
abstract::This paper reports an inverse arc-modulated radiation therapy planning technique based on linear models. It is implemented with a two-step procedure. First, fluence maps for 36 fixed-gantry beams are generated using a linear model-based intensity-modulated radiation therapy (IMRT) optimization algorithm. The 2D fluenc...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/55/13/020
更新日期:2010-07-07 00:00:00
abstract::The aim of this study was to investigate the utility of consistency metrics, such as inverse consistency, in contour-based deformable registration error analysis. Four images were acquired of the same phantom that has experienced varying levels of deformation. The deformations were simulated with deformable image regi...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/54/18/014
更新日期:2009-09-21 00:00:00
abstract::Geometric and penetration responses of a multihole focusing collimator to a point source have been determined using a digital computer and a ray tracing technique. Results are presented as point and line spread functions for collimated rays and penetrating rays, and as plane sensitivities and modulation transfer funct...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/26/1/011
更新日期:1981-01-01 00:00:00
abstract::Monitoring the spatio-temporal characteristics of microcirculation is crucial for studying the functional activities of biotissue and the mechanism of disease. However, conventional methods used to measure blood flow suffer from limited spatial resolution or the injection of exogenous substances or the need of scannin...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/49/7/020
更新日期:2004-04-07 00:00:00
abstract::The imaging performance of a high-resolution preclinical micro-positron emission tomography (micro-PET) system employing liquid xenon (LXe) as the gamma-ray detection medium was simulated. The arrangement comprises a ring of detectors consisting of trapezoidal LXe time projection ionization chambers and two arrays of ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/57/6/1685
更新日期:2012-03-21 00:00:00
abstract::Finding fluence maps for intensity-modulated radiation therapy (IMRT) can be formulated as a multi-criteria optimization problem for which Pareto optimal treatment plans exist. To account for the dose-per-fraction effect of fractionated IMRT, it is desirable to exploit radiobiological treatment plan evaluation criteri...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/53/22/006
更新日期:2008-11-21 00:00:00
abstract::Diffusion weighted magnetic resonance imaging offers a non-invasive tool to explore the three-dimensional structure of brain white matter in clinical practice. Anisotropic diffusion hardware phantoms are useful for the quantitative validation of this technique. This study provides guidelines on how to manufacture anis...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/53/19/009
更新日期:2008-10-07 00:00:00
abstract::In radiofrequency (RF) ablation or hyperthermia, internal temperature measurements and tissue property imaging are important to control their outputs and assess the treatment effect. Recently, magnetic resonance electrical impedance tomography (MREIT), as a non-invasive imaging method of internal conductivity distribu...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/58/8/2697
更新日期:2013-04-21 00:00:00
abstract::This work aims at developing a generic virtual source model (VSM) preserving all existing correlations between variables stored in a Monte Carlo pre-computed phase space (PS) file, for dose calculation and high-resolution portal image prediction. The reference PS file was calculated using the PENELOPE code, after the ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/61/14/5215
更新日期:2016-07-21 00:00:00
abstract::Compton scatter poses a significant threat to volumetric x-ray computed tomography, bringing cupping and streak artefacts thus impacting qualitative and quantitative imaging procedures. To perform appropriate scatter compensation, it is necessary to estimate the magnitude and spatial distribution of x-ray scatter. The...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/55/8/010
更新日期:2010-04-21 00:00:00
abstract::The purpose of this study was to examine the use of three physical image quality metrics in the calibration of an automatic exposure control (AEC) device for chest radiography with a computed radiography (CR) imaging system. The metrics assessed were signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR) and mean ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/59/9/2307
更新日期:2014-05-07 00:00:00
abstract::Uncertainties in determining clinically used relative biological effectiveness (RBE) values for ion beam therapy carry the risk of absolute and relative misestimations of RBE-weighted doses for clinical scenarios. This study assesses the consequences of hypothetical misestimations of input parameters to the RBE modell...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/57/23/7983
更新日期:2012-12-07 00:00:00
abstract::Does the posture of a patient have an effect on the organ and tissue absorbed doses caused by x-ray examinations? This study aims to find the answer to this question, based on Monte Carlo (MC) simulations of commonly performed x-ray examinations using adult phantoms modelled to represent humans in standing as well as ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/55/15/014
更新日期:2010-08-07 00:00:00
abstract::Heavy-ion radiotherapy exploits the high biological effectiveness of localized energy deposition delivered by so-called Bragg-peak particles. Recent publications have challenged the established procedures to calculate biological effective dose distributions in treatment planning. They emphasize the importance of very ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/54/7/N03
更新日期:2009-04-07 00:00:00
abstract::Usually, Monte Carlo models are validated against experimental data. However, models of multiple Coulomb scattering (MCS) in the Gaussian approximation are exceptional in that we have theories which are probably more accurate than the experiments which have, so far, been done to test them. In problems directly sensiti...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/1361-6560/aa6ce3
更新日期:2017-07-06 00:00:00