Investigating the robustness of ion beam therapy treatment plans to uncertainties in biological treatment parameters.

abstract：:A special parallel-plate ionization chamber was developed. The motivation for the construction of this new chamber was mainly to fulfil the need of a reference system for computed tomography standard beams in the Calibration Laboratory of IPEN. However, the chamber was tested also in standard radiation beams of mammog...

journal_title：Physics in medicine and biology

authors： Maia AF,Caldas LV

更新日期：2005-08-21 00:00:00

abstract：:Coronary flow rate remains complex to assess in clinical practice using non-invasive, non-ionizing imaging tools. In this study, we introduce 3D ultrafast Doppler coronary angiography (3D UDCA), an ultrasound-based method to assess coronary blood flows in three-dimensions at high volume-rate and in one single heartbea...

journal_title：Physics in medicine and biology

authors： Correia M,Maresca D,Goudot G,Villemain O,Bizé A,Sambin L,Tanter M,Ghaleh B,Pernot M

更新日期：2020-06-05 00:00:00

abstract：:The goal of this study was to determine the quantitative accuracy of our OSEM-APDI reconstruction method based on SPECT/CT imaging for Tc-99m, In-111, I-123, and I-131 isotopes. Phantom studies were performed on a SPECT/low-dose multislice CT system (Infinia-Hawkeye-4 slice, GE Healthcare) using clinical acquisition p...

journal_title：Physics in medicine and biology

authors： Shcherbinin S,Celler A,Belhocine T,Vanderwerf R,Driedger A

更新日期：2008-09-07 00:00:00

abstract：:Determining a multidimensional velocity field within microscale opaque fluid flows is needed in areas such as microfluidic devices, biofluid mechanics and hemodynamics research in animal studies. The ultrasonic particle image velocimetry (EchoPIV) technique is appropriate for measuring opaque flows by taking advantage...

journal_title：Physics in medicine and biology

authors： Qian M,Niu L,Wang Y,Jiang B,Jin Q,Jiang C,Zheng H

更新日期：2010-10-21 00:00:00

abstract：:This paper presents two methods for absorbed dose determination with ionization chambers at short distance from 60Co and 192Ir brachytherapy sources. The methods are modifications of the Bragg-Gray and large cavity principles given in the IAEA code of practice for high- and medium-energy photon beams. A non-uniformity...

journal_title：Physics in medicine and biology

authors： Tölli H,Johansson KA

更新日期：1998-11-01 00:00:00

abstract：:Average cross-sections for inactivation of dry ribonuclease by H, He and N projectiles with energies between 100 eV and 10 keV are presented. The trend of the damage cross-sections with particle energy is consistent with the trend of the molecular quasi-elastic scattering and ionization cross-sections. A tentative rad...

journal_title：Physics in medicine and biology

authors： Watt DE,Sutcliffe JF

更新日期：1975-11-01 00:00:00

abstract：:Assessment of image quality for digital x-ray mammography systems used in European screening programs relies mainly on contrast-detail CDMAM phantom scoring and requires the acquisition and analysis of many images in order to reduce variability in threshold detectability. Part II of this study proposes an alternative ...

journal_title：Physics in medicine and biology

authors： Monnin P,Marshall NW,Bosmans H,Bochud FO,Verdun FR

更新日期：2011-07-21 00:00:00

abstract：:Photon quality correction factors (kQy) for ionization chamber photon dosimetry in an epithermal neutron beam were determined according to a modified absorbed dose to water formalism which was extended to mixed radiation fields. We have studied two commercially available ionization chambers in the epithermal neutron b...

journal_title：Physics in medicine and biology

authors： Munck af Rosenschöld PM,Ceberg CP,Giusti V,Andreo P

更新日期：2002-07-21 00:00:00

abstract：:A two-probe technique has been developed to measure 125I in the thyroid. In this technique simultaneous emissions from a source are detected as coincidence events between two probes rather than as a sum peak in a single probe (the sum peak method). The background count rate when counting coincidence events between pro...

journal_title：Physics in medicine and biology

authors： Burns PA,Peggie JR

更新日期：1980-05-01 00:00:00

abstract：:The stochastic nature of cavitation implies visualization of the cavitation cloud in real-time and in a discriminative manner for the safe use of focused ultrasound therapy. This visualization is sometimes possible with standard echography, but it strongly depends on the quality of the scanner, and is hindered by diff...

journal_title：Physics in medicine and biology

authors： Arnal B,Baranger J,Demene C,Tanter M,Pernot M

更新日期：2017-02-07 00:00:00

abstract：:Approximately 70% of acute coronary artery disease is caused by unstable (vulnerable) plaques with an inflammation of the overlying cap and high lipid content. A rupturing of the inflamed cap of the plaque results in propagation of the thrombus into the lumen, blockage of the artery and acute ischaemic syndrome or sud...

journal_title：Physics in medicine and biology

authors： Shikhaliev PM,Xu T,Ducote JL,Easwaramoorthy B,Mukherjee J,Molloi S

更新日期：2006-02-21 00:00:00

abstract：:Dynamic contrast enhanced MRI (DCE-MRI) and pharmacokinetic models have been used to measure tumour permeability (K(trans)) and leakage volume (ve) in numerous studies. The construction of pharmacokinetic models describing such tissue properties relies on defining the blood plasma concentration of contrast agent with ...

journal_title：Physics in medicine and biology

authors： Ahearn TS,Staff RT,Redpath TW,Semple SI

更新日期：2004-05-21 00:00:00

abstract：:Precision image-guided small animal radiotherapy is rapidly advancing through the use of dedicated micro-irradiation devices. However, precise modeling of these devices in model-based dose-calculation algorithms such as Monte Carlo (MC) simulations continue to present challenges due to a combination of very small beam...

journal_title：Physics in medicine and biology

authors： Granton PV,Verhaegen F

更新日期：2013-05-21 00:00:00

abstract：:Over the last two years we have evaluated paediatric patient doses in projection radiography derived from exposure level (EL) in computed radiography (CR) in a large university hospital. Entrance surface air kerma (ESAK) for 3501 paediatric examinations was calculated from the EL, which is a dose index parameter relat...

journal_title：Physics in medicine and biology

authors： Vano E,Martinez D,Fernandez JM,Ordiales JM,Prieto C,Floriano A,Ten JI

更新日期：2008-06-21 00:00:00

abstract：:Voxel phantoms are human models based on computed tomographic or magnetic resonance images obtained from high-resolution scans of a single individual. They consist of a huge number of volume elements (voxels) and are at the moment the most precise representation of the human anatomy. The purpose of this paper is to in...

journal_title：Physics in medicine and biology

authors： Petoussi-Henss N,Zanki M,Fill U,Regulla D

更新日期：2002-01-07 00:00:00

abstract：:The purpose of this study was to derive a complete set of correction and perturbation factors for output factors (OF) and dose profiles. Modern small field detectors were investigated including a plastic scintillator (Exradin W1, SI), a liquid ionization chamber (microLion 31018, PTW), an unshielded diode (Exradin D1V...

journal_title：Physics in medicine and biology

authors： Papaconstadopoulos P,Tessier F,Seuntjens J

更新日期：2014-10-07 00:00:00

abstract：:This study examines the effectiveness of a single, first-order Arrhenius process in accurately modelling the thermally induced changes in the optical properties, particularly the reduced scattering coefficient, mu(s)', and the absorption coefficient, mu(a), of ex vivo rat prostate. Recent work has shown that mu(s)' ca...

journal_title：Physics in medicine and biology

authors： Skinner MG,Everts S,Reid AD,Vitkin IA,Lilge L,Sherar MD

更新日期：2000-05-01 00:00:00

abstract：:This study presents a combined small animal holding fixture system, termed a 'bridge capsule', which provides for small animal re-fixation with positional reproducibility. This system comprises separate holding fixtures for the head and lower body and a connecting part to a gas anesthesia system. A mouse is fixed in p...

journal_title：Physics in medicine and biology

authors： Kokuryo D,Kimura Y,Obata T,Yamaya T,Kawamura K,Zhang MR,Kanno I,Aoki I

更新日期：2010-07-21 00:00:00

abstract：:The derivative at constant direction is frequently used in inversion of cone-beam data. Several algorithms for computing the derivative have been proposed in the literature. The best algorithm to date has been proposed recently by Noo et al (2007 Phys. Med. Biol. 52 5393-414). In this note we propose a new, simple and...

journal_title：Physics in medicine and biology

authors： Katsevich A

更新日期：2011-02-21 00:00:00

abstract：:In critical organ in vivo x-ray dosimetry, the relative contaminating electron contribution to the total dose and total detector response outside the field will be different to the corresponding contributions at the central axis detector calibration position, mainly due to the effects of shielding in the linear accele...

journal_title：Physics in medicine and biology

authors： Edwards CR,Mountford PJ,Moloney AJ

更新日期：2006-12-21 00:00:00

abstract：:Histotripsy is a therapeutic ultrasound modality under development to liquefy tissue mechanically via bubble clouds. Image guidance of histotripsy requires both quantification of the bubble cloud activity and accurate delineation of the treatment zone. In this study, magnetic resonance (MR) and diagnostic ultrasound i...

journal_title：Physics in medicine and biology

authors： Anthony GJ,Bollen V,Hendley S,Antic T,Sammet S,Bader KB

更新日期：2019-05-02 00:00:00

abstract：:This study investigated the relationship between the specific absorption rate and temperature elevation in an anatomically-based model named NORMAN for exposure to radio-frequency far fields in the ICNIRP guidelines (1998 Health Phys. 74 494-522). The finite-difference time-domain method is used for analyzing the elec...

journal_title：Physics in medicine and biology

authors： Hirata A,Asano T,Fujiwara O

更新日期：2007-08-21 00:00:00

abstract：:The infrasonic part of the spectrum of the carotid artery wall vibration in the neck was obtained. Differences between the spectral content and vibrational amplitude in normal and occluded carotids were found. The application of this technique in clinical practice could be useful in the detection of the carotid insuff...

journal_title：Physics in medicine and biology

authors： Anastassiades AJ,Petounis AD

更新日期：1976-01-01 00:00:00

abstract：:This paper introduces a spatial-diversity method for speckle suppression in optical coherence microscopy. The method is based on combining interference signals from an array of detectors placed in the back focal plane of the objective lens, such that elements receive light backscattered from the sample volume at diffe...

journal_title：Physics in medicine and biology

authors： Schmitt JM

更新日期：1997-07-01 00:00:00

abstract：:Deep learning models are highly parameterized, resulting in difficulty in inference and transfer learning for image recognition tasks. In this work, we propose a layered pathway evolution method to compress a deep convolutional neural network (DCNN) for classification of masses in digital breast tomosynthesis (DBT). T...

journal_title：Physics in medicine and biology

authors： Samala RK,Chan HP,Hadjiiski LM,Helvie MA,Richter C,Cha K

更新日期：2018-05-01 00:00:00

abstract：:This paper presents a method to obtain the pencil-beam kernels that characterize a megavoltage photon beam generated in a flattening filter free (FFF) linear accelerator (linac) by deconvolution from experimental measurements at different depths. The formalism is applied to perform independent dose calculations in mod...

journal_title：Physics in medicine and biology

authors： Azcona JD,Barbés B,Wang L,Burguete J

更新日期：2016-01-07 00:00:00

abstract：:Fractional flow reserve (FFR) provides an objective physiological evaluation of stenosis severity. A technique that can measure FFR using only angiographic images would be a valuable tool in the cardiac catheterization laboratory. To perform this, the diseased blood flow can be measured with a first pass distribution ...

journal_title：Physics in medicine and biology

authors： Wong JT,Molloi S

更新日期：2008-07-21 00:00:00

abstract：:A novel digital x-ray detector has been assembled. The imaging system is based on a phosphor-coated charge-coupled device (CCD) obtained by direct deposition of a gadolinium oxysulphide scintillator onto the detector surface. The modulation transfer function has been measured along the two directions of the digital co...

journal_title：Physics in medicine and biology

authors： Gambaccini M,Taibi A,Del Guerra A,Marziani M,Tuffanelli A

更新日期：1996-12-01 00:00:00

abstract：:The signal properties of polycrystalline mercuric iodide (HgI2) film detectors, under irradiation conditions relevant to mammographic, radiographic, fluoroscopic and radiotherapy x-ray imaging, are reported. Each film detector consists of an approximately 230 to approximately 460 microm thick layer of HgI2 (fabricated...

journal_title：Physics in medicine and biology

authors： Su Z,Antonuk LE,El-Mohri Y,Hu L,Du H,Sawant A,Li Y,Wang Y,Yamamoto J,Zhao Q

更新日期：2005-06-21 00:00:00

abstract：:3D acquisition and reconstruction in positron emission tomography (PET) produce data with improved signal-to-noise ratios compared with conventional 2D slice-oriented methods. However, the sensitivity increase is accompanied by an increase in the number of scattered photons and random coincidences detected. This paper...

journal_title：Physics in medicine and biology

authors： Bailey DL,Meikle SR

更新日期：1994-03-01 00:00:00