On the correction, perturbation and modification of small field detectors in relative dosimetry.

Abstract:

:The purpose of this study was to derive a complete set of correction and perturbation factors for output factors (OF) and dose profiles. Modern small field detectors were investigated including a plastic scintillator (Exradin W1, SI), a liquid ionization chamber (microLion 31018, PTW), an unshielded diode (Exradin D1V, SI) and a synthetic diamond (microDiamond 60019, PTW). A Monte Carlo (MC) beam model was commissioned for use in small fields following two commissioning procedures: (1) using intermediate and moderately small fields (down to 2 × 2 cm(2)) and (2) using only small fields (0.5 × 0.5 cm(2) -2 × 2 cm(2)). In the latter case the detectors were explicitly modelled in the dose calculation. The commissioned model was used to derive the correction and perturbation factors with respect to a small point in water as suggested by the Alfonso formalism. In MC calculations the design of two detectors was modified in order to minimize or eliminate the corrections needed. The results of this study indicate that a commissioning process using large fields does not lead to an accurate estimation of the source size, even if a 2 × 2 cm(2) field is included. Furthermore, the detector should be explicitly modelled in the calculations. On the output factors, the scintillator W1 needed the smallest correction (+0.6%), followed by the microDiamond (+1.3%). Larger corrections were observed for the microLion (+2.4%) and diode D1V (-2.4%). On the profiles, significant corrections were observed out of the field on the gradient and tail regions. The scintillator needed the smallest corrections (-4%), followed by the microDiamond (-11%), diode D1V (+13%) and microLion (-15%). The major perturbations reported were due to volume averaging and high density materials that surround the active volumes. These effects presented opposite trends in both OF and profiles. By decreasing the radius of the microLion to 0.85 mm we could modify the volume averaging effect in order to achieve a discrepancy less than 1% for OF and 5% for profiles compared to water. Similar results were observed for the diode D1V if the radius was increased to 1 mm.

journal_name

Phys Med Biol

authors

Papaconstadopoulos P,Tessier F,Seuntjens J

doi

10.1088/0031-9155/59/19/5937

subject

Has Abstract

pub_date

2014-10-07 00:00:00

pages

5937-52

issue

19

eissn

0031-9155

issn

1361-6560

journal_volume

59

pub_type

杂志文章
  • Imaging of prompt gamma rays emitted during delivery of clinical proton beams with a Compton camera: feasibility studies for range verification.

    abstract::The purpose of this paper is to evaluate the ability of a prototype Compton camera (CC) to measure prompt gamma rays (PG) emitted during delivery of clinical proton pencil beams for prompt gamma imaging (PGI) as a means of providing in vivo verification of the delivered proton radiotherapy beams. A water phantom was i...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/18/7085

    authors: Polf JC,Avery S,Mackin DS,Beddar S

    更新日期:2015-09-21 00:00:00

  • A static beam delivery device for fast scanning proton arc-therapy.

    abstract::Arc-therapy is a dose delivery technique regularly applied in photon radiation therapy, and is currently subject of great interest for proton therapy as well. In this technique, proton beams are aimed at a tumor from different continuous ranges of incident directions (so called "arcs"). This technique can potentially ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/abe02b

    authors: Nesteruk KP,Bolsi A,Lomax AJ,Meer D,van de Water S,Schippers JM

    更新日期:2021-01-26 00:00:00

  • Biological dose representation for carbon-ion radiotherapy of unconventional fractionation.

    abstract::In carbon-ion radiotherapy, single-beam delivery each day in alternate directions has been common practice for efficient operation, taking advantage of the Bragg peak and the relative biological effectiveness (RBE) for uniform dose conformation to a tumor. Treatments are usually fractionated and treatment plans are ev...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/62/3/1062

    authors: Kanematsu N,Inaniwa T

    更新日期:2017-02-07 00:00:00

  • Extended three-compartment model for the transport and distribution of Hippuran.

    abstract::The distribution and transport of Hippuran is discussed. The activity leaving both kidneys has been calculated and compared with the bladder activity. It is shown that the Impulse Response Function of the ureter and bladder may be obtained by deconvolution, and data are presented relating to studies on one patient. ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/26/2/002

    authors: Knesaurek K,Spaventi S

    更新日期:1981-03-01 00:00:00

  • A comparison of direct reconstruction algorithms in proton computed tomography.

    abstract::Several direct algorithms have been proposed to take into account the non-linear path of protons in the reconstruction of a proton CT (pCT) image. This paper presents a comparison between five of them, in terms of spatial resolution and relative stopping power (RSP) accuracy. Our comparison includes (1) a distance-dri...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab7d53

    authors: Khellaf F,Krah N,Létang JM,Collins-Fekete CA,Rit S

    更新日期:2020-06-01 00:00:00

  • Single spectrum three-material decomposition with grating-based x-ray phase-contrast CT.

    abstract::Grating-based x-ray phase-contrast imaging provides three simultaneous image channels originating from a single image acquisition. While the phase signal provides direct access to the electron density in tomography, there is additional information on sub-resolutional structural information which is called dark-field s...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab9704

    authors: Braig EM,Pfeiffer D,Willner M,Sellerer T,Taphorn K,Petrich C,Scholz J,Petzold L,Birnbacher L,Dierolf M,Pfeiffer F,Herzen J

    更新日期:2020-09-18 00:00:00

  • Comparison of temperature distributions in interstitial hyperthermia: experiments in bovine tongues versus generic simulations.

    abstract::Temperature distributions resulting from hyperthermia treatments on isolated perfused bovine tongues were compared with simulations by a treatment planning system. The aim was to test whether the discrete vessel model used for the treatment planning is able to predict correct generic temperature distributions. Tongues...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/43/5/011

    authors: Raaymakers BW,Crezee J,Lagendijk JJ

    更新日期:1998-05-01 00:00:00

  • Kill painting of hypoxic tumors with multiple ion beams.

    abstract::We report on a novel method for simultaneous biological optimization of treatment plans for hypoxic tumors using multiple ion species. Our previously introduced kill painting approach, where the overall cell killing is optimized on biologically heterogeneous targets, was expanded with the capability of handling differ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aafe40

    authors: Sokol O,Krämer M,Hild S,Durante M,Scifoni E

    更新日期:2019-02-08 00:00:00

  • Conversion factors for the estimation of effective dose in paediatric cardiac angiography.

    abstract::Conversion factors, which relate the kerma-area product to effective dose, have been estimated for paediatric cardiac x-ray angiography. Monte Carlo techniques have been used to calculate the conversion factors for a wide range of projection angles for children of five ages and for adults. Correction factors are provi...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/45/10/323

    authors: Schmidt PW,Dance DR,Skinner CL,Smith IA,McNeill JG

    更新日期:2000-10-01 00:00:00

  • Computation of bremsstrahlung X-ray spectra and comparison with spectra measured with a Ge(Li) detector.

    abstract::A method of computing theoretical X-ray spectra in the range 30-150 kV is presented. The theoretical spectra are compared with constant potential, high resolution spectra from a tungsten target measured with a Ge(Li) detector, for a range of target angles, tube voltage and filtrations. Above 100 kV the spectra were al...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/24/3/002

    authors: Birch R,Marshall M

    更新日期:1979-05-01 00:00:00

  • Integration of dynamic contrast-enhanced magnetic resonance imaging and T2-weighted imaging radiomic features by a canonical correlation analysis-based feature fusion method to predict histological grade in ductal breast carcinoma.

    abstract::Tumour histological grade has prognostic implications in breast cancer. Tumour features in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and T2-weighted (T2W) imaging can provide related and complementary information in the analysis of breast lesions to improve MRI-based histological status prediction...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab3fd3

    authors: Fan M,Liu Z,Xie S,Xu M,Wang S,Gao X,Li L

    更新日期:2019-10-23 00:00:00

  • An optimized leaf-setting algorithm for beam intensity modulation using dynamic multileaf collimators.

    abstract::A leaf-setting algorithm is developed for generating arbitrary beam intensity profiles in discrete levels using dynamic multileaf collimators (DMLCs). The algorithm starts with the algebraic expression for the area under the beam profile. It is shown that the coefficients in this expression can be transformed into the...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/43/6/019

    authors: Ma L,Boyer AL,Xing L,Ma CM

    更新日期:1998-06-01 00:00:00

  • Visually interpretable deep network for diagnosis of breast masses on mammograms.

    abstract::Recently, deep learning technology has achieved various successes in medical image analysis studies including computer-aided diagnosis (CADx). However, current CADx approaches based on deep learning have a limitation in interpreting diagnostic decisions. The limited interpretability is a major challenge for practical ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aaef0a

    authors: Kim ST,Lee JH,Lee H,Ro YM

    更新日期:2018-12-04 00:00:00

  • Infrared and visible thermoluminescence signals of Tm-doped CaF2 measured by a semiconductor photodiode.

    abstract::A silicon semiconductor photodiode was used to measure the TL-signal of TLD-300 (CaF2:Tm) detectors irradiated with 60Co gamma rays and 226Ra alpha particles. The applied dose values varied from 0.12 to 14.3 Gy for gamma rays and from about 50 to 300 Gy for alpha particles. Because of the infrared sensitivity of the p...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/33/12/006

    authors: Meissner P,Jacob M,Rassow J

    更新日期:1988-12-01 00:00:00

  • Radiance and particle fluence.

    abstract::The concepts of radiance and fluence are fundamental to the description of a radiation field. The International Commission on Radiological Units and Measurements (ICRU) has defined fluence in terms of the number of the radiation particles crossing a small sampling sphere. A second definition has been proposed in which...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/39/6/011

    authors: Papiez L,Battista JJ

    更新日期:1994-06-01 00:00:00

  • A new approach to develop computer-aided detection schemes of digital mammograms.

    abstract::The purpose of this study is to develop a new global mammographic image feature analysis based computer-aided detection (CAD) scheme and evaluate its performance in detecting positive screening mammography examinations. A dataset that includes images acquired from 1896 full-field digital mammography (FFDM) screening e...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/11/4413

    authors: Tan M,Qian W,Pu J,Liu H,Zheng B

    更新日期:2015-06-07 00:00:00

  • Curvature correction of retinal OCTs using graph-based geometry detection.

    abstract::In this paper, we present a new algorithm as an enhancement and preprocessing step for acquired optical coherence tomography (OCT) images of the retina. The proposed method is composed of two steps, first of which is a denoising algorithm with wavelet diffusion based on a circular symmetric Laplacian model, and the se...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/58/9/2925

    authors: Kafieh R,Rabbani H,Abramoff MD,Sonka M

    更新日期:2013-05-07 00:00:00

  • Pitch dependence of longitudinal sampling and aliasing effects in multi-slice helical computed tomography (CT).

    abstract::In this work, we investigate longitudinal sampling and aliasing effects in multi-slice helical CT. We demonstrate that longitudinal aliasing can be a significant, complicated, and potentially detrimental effect in multi-slice helical CT reconstructions. Multi-slice helical CT scans are generally undersampled longitudi...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/47/15/318

    authors: La Rivière PJ,Pan X

    更新日期:2002-08-07 00:00:00

  • Thermoluminescent response and relative efficiency of TLD-100 exposed to low-energy x-rays.

    abstract::The dose-response of LiF:Mg,Ti (TLD-100) exposed to 15 and 35 kVp (8.0 +/- 0.1 and 8.1 +/- 0.1 keV effective energy respectively) x-rays and 60Co gamma-rays has been measured in the dose interval from (1.2-5.4) x 10(3) Gy for x-rays, and from 0.14 to 850 Gy for gamma-rays. In both cases the total TL signal and glow cu...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/43/8/006

    authors: Gamboa-deBuen I,Buenfil AE,Ruiz CG,Rodríguez-Villafuerte M,Flores A,Brandan ME

    更新日期:1998-08-01 00:00:00

  • Mathematical modelling of the human cardiovascular system in the presence of stenosis.

    abstract::This paper reports a theoretical study on the distribution of blood flow in the human cardiovascular system when one or more blood vessels are affected by stenosis. The analysis employs a mathematical model of the entire system based on the finite element method. The arterial-venous network is represented by a large n...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/38/3/004

    authors: Sud VK,Srinivasan RS,Charles JB,Bungo MW

    更新日期:1993-03-01 00:00:00

  • Synchrotron microangiography with no contrast agent.

    abstract::Coherent x-rays from synchrotron sources are increasingly used in non-conventional radiological techniques ('phase-contrast' radiology). Our experiments demonstrate that by using white (unmonochromatic) radiation and a time-resolving system, it is possible to image microscopic details of moving blood vessels in differ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/49/4/002

    authors: Hwu Y,Tsai WL,Je JH,Seol SK,Kim B,Groso A,Margaritondo G,Lee KH,Seong JK

    更新日期:2004-02-21 00:00:00

  • The impact of respiratory motion on tumor quantification and delineation in static PET/CT imaging.

    abstract::Our aim is to investigate the impact of respiratory motion on tumor quantification and delineation in static PET/CT imaging using a population of patient respiratory traces. A total of 1295 respiratory traces acquired during whole body PET/CT imaging were classified into three types according to the qualitative shape ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/54/24/007

    authors: Liu C,Pierce LA 2nd,Alessio AM,Kinahan PE

    更新日期:2009-12-21 00:00:00

  • In vivo evaluation of a new system for 3D computerized angiography.

    abstract::A new system has been designed and built to validate the concept of 3D computerized angiography (CA). This system can acquire a set of 2D digital subtracted angiography images while rotating around a patient and then, using these images, reconstruct a 3D representation of the opacified vasculature. The design principl...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/39/3/020

    authors: Saint-Félix D,Trousset Y,Picard C,Ponchut C,Roméas R,Rougée A

    更新日期:1994-03-01 00:00:00

  • Effects of body habitus on internal radiation dose calculations using the 5-year-old anthropomorphic male models.

    abstract::Computational phantoms are commonly used in internal radiation dosimetry to assess the amount and distribution pattern of energy deposited in various parts of the human body from different internal radiation sources. Radiation dose assessments are commonly performed on predetermined reference computational phantoms wh...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa75b4

    authors: Xie T,Kuster N,Zaidi H

    更新日期:2017-07-13 00:00:00

  • Lasso logistic regression to derive workflow-specific algorithm performance requirements as demonstrated for head and neck cancer deformable image registration in adaptive radiation therapy.

    abstract::As automation in radiation oncology becomes more common, it is important to determine which algorithms are equivalent for a given workflow. Often, algorithm comparisons are performed in isolation; however, clinical context can provide valuable insight into the importance of algorithm features and error magnification i...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab9fc8

    authors: Weppler S,Schinkel C,Kirkby C,Smith W

    更新日期:2020-09-28 00:00:00

  • Optimization of the accuracy of retention and washout measurements of 99mTc-Sestamibi from breast tumours using an anthropomorphic phantom.

    abstract::Quantifying the retention or washout of (99m)Tc-Sestamibi (MIBI) in breast tumours in vivo may provide a basis for predicting the chemotherapy response. The aim of this study is to investigate the variations and limitations of the different methods used to quantify these parameters. A phantom was developed that allowe...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/50/9/013

    authors: Marshall C,Griffiths PA

    更新日期:2005-05-07 00:00:00

  • MR-based keyhole SPECT for small animal imaging.

    abstract::The rationale for multi-modality imaging is to integrate the strengths of different imaging technologies while reducing the shortcomings of an individual modality. The work presented here proposes a limited-field-of-view (LFOV) SPECT reconstruction technique that can be implemented on a multi-modality MR/SPECT system ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/56/3/010

    authors: Lee KS,Roeck WW,Gullberg GT,Nalcioglu O

    更新日期:2011-02-07 00:00:00

  • Dose measurements in inhomogeneous bone/tissue and lung/tissue phantoms for angiography using synchrotron radiation.

    abstract::For angiography using synchrotron radiation we measured the absorbed dose distribution in inhomogeneous phantoms with thin LiF:Mg, Cu, P, LiF:Mg, Ti thermoluminescent dosimeters (TLDs) in tissue and lung substitutes, and with Mg2SiO4:Tb TLDs in bone substitute for 33.32 keV monoenergetic photons from synchrotron radia...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/46/3/308

    authors: Nariyama N,Namito Y,Ban S,Hirayama H

    更新日期:2001-03-01 00:00:00

  • Comparison of a finite-element multigroup discrete-ordinates code with Monte Carlo for radiotherapy calculations.

    abstract::Radiotherapy calculations often involve complex geometries such as interfaces between materials of vastly differing atomic number, such as lung, bone and/or air interfaces. Monte Carlo methods have been used to calculate accurately the perturbation effects of the interfaces. However, these methods can be computational...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/51/9/010

    authors: Gifford KA,Horton JL,Wareing TA,Failla G,Mourtada F

    更新日期:2006-05-07 00:00:00

  • Analytical modeling of relative luminescence efficiency of Al2O3:C optically stimulated luminescence detectors exposed to high-energy heavy charged particles.

    abstract::The objective of this work is to test analytical models to calculate the luminescence efficiency of Al(2)O(3):C optically stimulated luminescence detectors (OSLDs) exposed to heavy charged particles with energies relevant to space dosimetry and particle therapy. We used the track structure model to obtain an analytica...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/57/2/437

    authors: Sawakuchi GO,Yukihara EG

    更新日期:2012-01-21 00:00:00