Cross-sections for the inactivation of ribonuclease by slow heavy ions.

abstract：:A method is described which offers an alternative to conventional Fourier phase/amplitude imaging for analysing representative LV cycles obtained from first-pass cardiac studies. The method involves applying factor analysis to the data and producing functional images of the first two factor loadings after polar transf...

journal_title：Physics in medicine and biology

authors： Houston AS,Elliott AT,Stone DL

更新日期：1982-10-01 00:00:00

abstract：:Motion mitigation strategies are crucial for scanned particle therapy of mobile tumours in order to prevent geometrical target miss and interplay effects. We developed a patient-specific respiratory motion model based on simultaneously acquired time-resolved volumetric MRI and 2D abdominal ultrasound images. We presen...

journal_title：Physics in medicine and biology

authors： Giger AT,Krieger M,Jud C,Duetschler A,Salomir R,Bieri O,Bauman G,Nguyen D,Weber DC,Lomax AJ,Zhang Y,Cattin PC

更新日期：2020-07-28 00:00:00

abstract：:Acidic drinks and foodstuffs can demineralize dental hard tissues, leading to a pathological condition known as dental erosion, which is of increasing clinical concern. The first step in enamel dissolution is a demineralization of the outer few micrometres of tissue, which results in a softening of the structure. The ...

journal_title：Physics in medicine and biology

authors： Barbour ME,Shellis RP

更新日期：2007-02-21 00:00:00

abstract：:The Patlak graphical method is widely used in parametric imaging for modeling irreversible radiotracer kinetics in dynamic PET. The net influx rate of radiotracer can be determined from the slope of the Patlak plot. The implementation of the standard Patlak method requires the knowledge of full-time input function fro...

journal_title：Physics in medicine and biology

authors： Zuo Y,Qi J,Wang G

更新日期：2018-08-10 00:00:00

abstract：:Intensity modulated particle therapy (IMPT) with carbon ions can generate highly conformal treatment plans; however, IMPT is limited in robustness against range and positioning uncertainty. This is particularly true for moving targets, even though all motion states of a 4DCT are considered in 4D-IMPT. Here, we expand ...

journal_title：Physics in medicine and biology

authors： Wolf M,Anderle K,Durante M,Graeff C

更新日期：2020-11-06 00:00:00

abstract：:Absorbed dose values were determined under the reference conditions in a phantom irradiated by high-energy photon beams with quality varying between 60Co gamma rays and 25 MV X-rays, using four commonly employed types of ionisation chamber. The ionisation chamber readings were converted to absorbed dose values applyin...

journal_title：Physics in medicine and biology

authors： Mijnheer BJ,Wittkämper FW

更新日期：1986-04-01 00:00:00

abstract：:3D breast modelling for 2D and 3D breast x-ray imaging would benefit from the availability of digital and physical phantoms that reproduce accurately the complexity of the breast anatomy. While a number of groups have produced digital phantoms with increasing level of complexity, physical phantoms reproducing that sof...

journal_title：Physics in medicine and biology

authors： Esposito G,Mettivier G,Bliznakova K,Bliznakov Z,Bosmans H,Bravin A,Buliev I,Di Lillo F,Ivanov D,Minutillo M,Sarno A,Vignero J,Russo P

更新日期：2019-03-27 00:00:00

abstract：:Energy and angular distributions of electron beams with different energies were simulated by Monte Carlo calculations. These beams were generated by the NOVAC7 system (Hitesys, Italy), a mobile electron accelerator specifically dedicated to intra-operative radiation therapy (IORT). The electron beam simulations were v...

journal_title：Physics in medicine and biology

authors： Pimpinella M,Mihailescu D,Guerra AS,Laitano RF

更新日期：2007-10-21 00:00:00

abstract：:Heterogeneity corrections for radiotherapy dose calculations are based on the electron density of the disturbing heterogeneity. However, when CT planning a radiotherapy treatment, where metallic hip implants are present, considerable artefacts are seen in the images. Often, an additional problem arises whereby no info...

journal_title：Physics in medicine and biology

authors： Coolens C,Childs PJ

更新日期：2003-06-07 00:00:00

abstract：:An experimental investigation of the central axis depth-dose and stopping rate distribution of the SIN biomedical pion beam is reported. The pion stopping rate in a thin disc of tissue-equivalent plastic was determined using a counter telescope. The dose rate at the position of this dic 'target' was measured using a s...

journal_title：Physics in medicine and biology

authors： Nordell B,Baarli J,Sullivan AH,Zielczynski M

更新日期：1977-05-01 00:00:00

abstract：:The authors have developed an apparatus able to generate ID intensity-modulated beams, using only one moving absorber within the irradiation field. A procedure for deriving optimized absorber-speed profiles in order to produce the desired fluence/dose profiles has been suggested. Experimental tests show that the syste...

journal_title：Physics in medicine and biology

authors： Fiorino C,Lev A,Fusca M,Cattaneo GM,Rudello F,Calandrino R

更新日期：1995-02-01 00:00:00

abstract：:It seems likely that long term patency of small bore vascular prostheses is dependent upon, among other things, the mechanical properties of their walls. Arteries are visco-elastic but there is no accurate method of measuring the visco-elasticity of arterial substitutes in vivo. The most successful vascular substitute...

journal_title：Physics in medicine and biology

authors： Chapman BL,Charlesworth D

更新日期：1983-09-01 00:00:00

abstract：:The silicon photomultiplier (Si-PM) is a promising photo-detector for PET for use in magnetic resonance imaging (MRI) systems because it has high gain and is insensitive to static magnetic fields. Recently we developed a Si-PM-based depth-of-interaction PET system for small animals and performed simultaneous measureme...

journal_title：Physics in medicine and biology

authors： Yamamoto S,Watabe T,Watabe H,Aoki M,Sugiyama E,Imaizumi M,Kanai Y,Shimosegawa E,Hatazawa J

更新日期：2012-01-21 00:00:00

abstract：:We study the treatment plan optimization problem for volumetric modulated arc therapy (VMAT). We propose a new column-generation-based algorithm that takes into account bounds on the gantry speed and dose rate, as well as an upper bound on the rate of change of the gantry speed, in addition to MLC constraints. The alg...

journal_title：Physics in medicine and biology

authors： Peng F,Jia X,Gu X,Epelman MA,Romeijn HE,Jiang SB

更新日期：2012-07-21 00:00:00

abstract：:We present a method to include robustness in a multi-criteria optimization (MCO) framework for intensity-modulated proton therapy (IMPT). The approach allows one to simultaneously explore the trade-off between different objectives as well as the trade-off between robustness and nominal plan quality. In MCO, a database...

journal_title：Physics in medicine and biology

authors： Chen W,Unkelbach J,Trofimov A,Madden T,Kooy H,Bortfeld T,Craft D

更新日期：2012-02-07 00:00:00

abstract：:A new function to treat tetrahedral-mesh geometry was implemented in the particle and heavy ion transport code systems. To accelerate the computational speed in the transport process, an original algorithm was introduced to initially prepare decomposition maps for the container box of the tetrahedral-mesh geometry. Th...

journal_title：Physics in medicine and biology

authors： Furuta T,Sato T,Han MC,Yeom YS,Kim CH,Brown JL,Bolch WE

更新日期：2017-06-21 00:00:00

abstract：:A new multiplicative correction factor for tissue heterogeneities based on an exact expression for homogeneous non-unit-density media is proposed. O'Connor's density scaling theorem is invoked to evaluate the medium-specific tissue-maximum ratios used in the exact formulation. Monte Carlo calculations were performed a...

journal_title：Physics in medicine and biology

authors： Petti PL,Siddon RL,Bjärngard BE

更新日期：1986-10-01 00:00:00

abstract：:Ring artifacts in cone beam computed tomography (CBCT) images are caused by pixel gain variations using flat-panel detectors, and may lead to structured non-uniformities and deterioration of image quality. The purpose of this study is to propose a method of general ring artifact removal in CBCT images. This method is ...

journal_title：Physics in medicine and biology

authors： Liang X,Zhang Z,Niu T,Yu S,Wu S,Li Z,Zhang H,Xie Y

更新日期：2017-07-07 00:00:00

abstract：:Knowledge of what dose-volume histograms can be expected for a previously unseen patient could increase consistency and quality in radiotherapy treatment planning. We propose a machine learning method that uses previous treatment plans to predict such dose-volume histograms. The key to the approach is the framing of d...

journal_title：Physics in medicine and biology

authors： Skarpman Munter J,Sjölund J

更新日期：2015-09-07 00:00:00

abstract：:Over the course of radiation therapy, a patient's anatomy may change substantially. The relatively recent addition of frequent in-room imaging to assist with patient localization has provided a database of images that may be used to recalculate dose distributions for adaptive radiotherapy purposes. The TomoTherapy Hi-...

journal_title：Physics in medicine and biology

authors： Pukala J,Meeks SL,Bova FJ,Langen KM

更新日期：2011-12-21 00:00:00

abstract：:The reference levels for testing compliance of human exposure with radio-frequency (RF) safety limits have been derived from very simplified models of the human. In order to validate these findings for anatomical models, we investigated the absorption characteristics for various anatomies ranging from 6 year old child...

journal_title：Physics in medicine and biology

authors： Kühn S,Jennings W,Christ A,Kuster N

更新日期：2009-02-21 00:00:00

abstract：:The quantification of tumor motion in sites affected by respiratory motion is of primary importance to improve treatment accuracy. To account for motion, different studies analyzed the translational component only, without focusing on the rotational component, which was quantified in a few studies on the prostate with...

journal_title：Physics in medicine and biology

authors： Paganelli C,Lee D,Greer PB,Baroni G,Riboldi M,Keall P

更新日期：2015-09-21 00:00:00

abstract：:Ion beam radiotherapy exploits the finite range of ion beams and the increased dose deposition of ions toward the end of their range in material. This results in high dose conformation to the target region, which can be further increased using scanning ion beams. The standard method for patient-plan verification in io...

journal_title：Physics in medicine and biology

authors： Martišíková M,Brons S,Hesse BM,Jäkel O

更新日期：2013-03-21 00:00:00

abstract：:A multimodal micro-computed tomography (CT) and multi-spectral structured light imaging (SLI) system is introduced and systematically analyzed to test its feasibility to aid in margin delineation during breast conserving surgery (BCS). Phantom analysis of the micro-CT yielded a signal-to-noise ratio of 34, a contrast ...

journal_title：Physics in medicine and biology

authors： McClatchy DM,Rizzo EJ,Meganck J,Kempner J,Vicory J,Wells WA,Paulsen KD,Pogue BW

更新日期：2017-11-10 00:00:00

abstract：:Cardiac and respiratory motion artefacts in PET imaging have been traditionally resolved by acquiring the data in gated mode. However, gated PET images are usually characterized by high noise content due to their low photon statistics. In this paper, we present a novel 4D model for the PET imaging system, which can in...

journal_title：Physics in medicine and biology

authors： Qiao F,Pan T,Clark JW Jr,Mawlawi OR

更新日期：2006-08-07 00:00:00

abstract：:In a recent paper (Chamberland et al 2016 Phys. Med. Biol. 61 8214) develop a new Monte Carlo code called egs_brachy for brachytherapy treatments. It is based on EGSnrc, and written in the C++ programming language. In order to benchmark the egs_brachy code, the authors use it in various test case scenarios in which co...

journal_title：Physics in medicine and biology

authors： Yegin G

更新日期：2018-02-02 00:00:00

abstract：:The probability of a photon (x-ray, gamma-ray, bremsstrahlung, etc) of a given energy E undergoing absorption or scattering when traversing a layer of material Z can be expressed quantitatively in terms of a linear attenuation coefficient mu (cm(-1)). Since mu is dependent on the material's density, rho (g cm(-3)), wh...

journal_title：Physics in medicine and biology

authors： Hubbell JH

更新日期：1999-01-01 00:00:00

abstract：:The objective of this study was to be able to distinguish between healthy skin tissue and malignant ones, furthermore determining a unique pattern of roughness for each skin lesion by microtopographic analysis of the skin surface of Mexican patients during the period from April to October 2002. The standard technique ...

journal_title：Physics in medicine and biology

authors： del Carmen López Pacheco M,da Cunha Martins-Costa MF,Zapata AJ,Cherit JD,Gallegos ER

更新日期：2005-12-07 00:00:00

abstract：:This study presents a new approach to accurately account for the medium-dependent effect in model-based dose calculations for kilovoltage (kV) x-rays. This approach is based on the hypothesis that the correction factors needed to convert dose from model-based dose calculations to absorbed dose-to-medium depend on both...

journal_title：Physics in medicine and biology

authors： Pawlowski JM,Ding GX

更新日期：2011-07-07 00:00:00

abstract：:In this work, a procedure, based on Monte Carlo techniques, to analyse the effect on the tumour control probability of the time interval between surgery and postoperative radiotherapy is presented. The approach includes the tumour growth as well as the survival of tumour cells undergoing fractionated radiotherapy. Bot...

journal_title：Physics in medicine and biology

authors： Al-Dweri FM,Guirado D,Lallena AM,Pedraza V

更新日期：2004-07-07 00:00:00