Comment on 'egs_brachy: a versatile and fast Monte Carlo code for brachytherapy'.

Abstract:

:In a recent paper (Chamberland et al 2016 Phys. Med. Biol. 61 8214) develop a new Monte Carlo code called egs_brachy for brachytherapy treatments. It is based on EGSnrc, and written in the C++ programming language. In order to benchmark the egs_brachy code, the authors use it in various test case scenarios in which complex geometry conditions exist. Another EGSnrc based brachytherapy dose calculation engine, BrachyDose, is used for dose comparisons. The authors fail to prove that egs_brachy can produce reasonable dose values for brachytherapy sources in a given medium. The dose comparisons in the paper are erroneous and misleading. egs_brachy should not be used in any further research studies unless and until all the potential bugs are fixed in the code.

journal_name

Phys Med Biol

authors

Yegin G

doi

10.1088/1361-6560/aa9ea1

subject

Has Abstract

pub_date

2018-02-02 00:00:00

pages

038001

issue

3

eissn

0031-9155

issn

1361-6560

journal_volume

63

pub_type

评论,杂志文章,信件
  • The calibration of CT Hounsfield units for radiotherapy treatment planning.

    abstract::Computer tomographic (CT) scans are used to correct for tissue inhomogeneities in radiotherapy treatment planning. In order to guarantee a precise treatment, it is important to obtain the relationship between CT Hounsfield units and electron densities (or proton stopping powers for proton radiotherapy), which is the b...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/41/1/009

    authors: Schneider U,Pedroni E,Lomax A

    更新日期:1996-01-01 00:00:00

  • Beam angle selection incorporation of anatomical heterogeneities for pencil beam scanning charged-particle therapy.

    abstract::In charged particle therapy with pencil beam scanning (PBS), localization of the dose in the Bragg peak makes dose distributions sensitive to lateral tissue heterogeneities. The sensitivity of a PBS plan to lateral tissue heterogeneities can be reduced by selecting appropriate beam angles. The purpose of this study is...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/61/24/8664

    authors: Toramatsu C,Inaniwa T

    更新日期:2016-12-21 00:00:00

  • Intermittent cryogen spray cooling for optimal heat extraction during dermatologic laser treatment.

    abstract::Fast heat extraction is critically important to obtain the maximal benefit of cryogen spray cooling (CSC) during laser therapy of shallow skin lesions, such as port wine stain birthmarks. However, a film of liquid cryogen can build up on the skin surface, impairing heat transfer due to the relatively low thermal condu...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/47/18/301

    authors: Majaron B,Svaasand LO,Aguilar G,Nelson JS

    更新日期:2002-09-21 00:00:00

  • 4D image reconstruction for emission tomography.

    abstract::An overview of the theory of 4D image reconstruction for emission tomography is given along with a review of the current state of the art, covering both positron emission tomography and single photon emission computed tomography (SPECT). By viewing 4D image reconstruction as a matter of either linear or non-linear par...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1088/0031-9155/59/22/R371

    authors: Reader AJ,Verhaeghe J

    更新日期:2014-11-21 00:00:00

  • Beam characterisation of the 1.5 T MRI-linac.

    abstract::As a prerequisite for clinical treatments it was necessary to characterize the Elekta 1.5 T MRI-linac 7 MV FFF radiation beam. Following acceptance testing, beam characterization data were acquired with Semiflex 3D (PTW 31021), microDiamond (PTW 60019), and Farmer-type (PTW 30013 and IBA FC65-G) detectors in an Elekta...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aab566

    authors: Woodings SJ,Bluemink JJ,de Vries JHW,Niatsetski Y,van Veelen B,Schillings J,Kok JGM,Wolthaus JWH,Hackett SL,van Asselen B,van Zijp HM,Pencea S,Roberts DA,Lagendijk JJW,Raaymakers BW

    更新日期:2018-04-19 00:00:00

  • Patch-based anisotropic diffusion scheme for fluorescence diffuse optical tomography--part 2: image reconstruction.

    abstract::Fluorescence diffuse optical tomography (fDOT) provides 3D images of fluorescence distributions in biological tissue, which represent molecular and cellular processes. The image reconstruction problem is highly ill-posed and requires regularisation techniques to stabilise and find meaningful solutions. Quadratic regul...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/61/4/1452

    authors: Correia T,Koch M,Ale A,Ntziachristos V,Arridge S

    更新日期:2016-02-21 00:00:00

  • Prototyping a large field size IORT applicator for a mobile linear accelerator.

    abstract::The treatment of large tumors such as sarcomas with intra-operative radiotherapy using a Mobetron is often complicated because of the limited field size of the primary collimator and the available applicators (max Ø100 mm). To circumvent this limitation a prototype rectangular applicator of 80 x 150 mm(2) was designed...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/53/8/006

    authors: Janssen RW,Faddegon BA,Dries WJ

    更新日期:2008-04-21 00:00:00

  • A parallel adaptive finite element simplified spherical harmonics approximation solver for frequency domain fluorescence molecular imaging.

    abstract::Fluorescence molecular imaging/tomography may play an important future role in preclinical research and clinical diagnostics. Time- and frequency-domain fluorescence imaging can acquire more measurement information than the continuous wave (CW) counterpart, improving the image quality of fluorescence molecular tomogra...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/55/16/002

    authors: Lu Y,Zhu B,Shen H,Rasmussen JC,Wang G,Sevick-Muraca EM

    更新日期:2010-08-21 00:00:00

  • An analysis of the accuracy of magnetic resonance flip angle measurement methods.

    abstract::Several methods of flip angle mapping for magnetic resonance imaging have been proposed. We evaluated the accuracy of five methods of flip angle measurement in the presence of measurement noise. Our analysis was performed in a closed form by propagation of probability density functions (PDFs). The flip angle mapping m...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/55/20/008

    authors: Morrell GR,Schabel MC

    更新日期:2010-10-21 00:00:00

  • Optimizing wavelength choice for quantitative optoacoustic imaging using the Cramer-Rao lower bound.

    abstract::Several papers have recently addressed the issue of estimating chromophore concentration in optoacoustic imaging (OAI) using multiple wavelengths. The choice of wavelengths obviously affects the accuracy and precision of the estimates. One might assume that the wavelengths that maximize the extinction coefficients of ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/55/23/004

    authors: Modgil D,La Riviére PJ

    更新日期:2010-12-07 00:00:00

  • Time-invariant component-based normalization for a simultaneous PET-MR scanner.

    abstract::Component-based normalization is a method used to compensate for the sensitivity of each of the lines of response acquired in positron emission tomography. This method consists of modelling the sensitivity of each line of response as a product of multiple factors, which can be classified as time-invariant, time-varian...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/61/9/3554

    authors: Belzunce MA,Reader AJ

    更新日期:2016-05-07 00:00:00

  • Development of a fast Monte Carlo dose calculation system for online adaptive radiation therapy quality assurance.

    abstract::Online adaptive radiation therapy (ART) based on real-time magnetic resonance imaging represents a paradigm-changing treatment scheme. However, conventional quality assurance (QA) methods based on phantom measurements are not feasible with the patient on the treatment couch. The purpose of this work is to develop a fa...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa6e38

    authors: Wang Y,Mazur TR,Park JC,Yang D,Mutic S,Li HH

    更新日期:2017-06-21 00:00:00

  • The impact of calibration phantom errors on dual-energy digital mammography.

    abstract::Microcalcification is one of the earliest and main indicators of breast cancer. Because dual-energy digital mammography could suppress the contrast between the adipose and glandular tissues of the breast, it is considered a promising technique that will improve the detection of microcalcification. In dual-energy digit...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/53/22/004

    authors: Mou X,Chen X,Sun L,Yu H,Ji Z,Zhang L

    更新日期:2008-11-21 00:00:00

  • Feasibility of replacing patient specific cutouts with a computer-controlled electron multileaf collimator.

    abstract::A motorized electron multileaf collimator (eMLC) was developed as an add-on device to the Varian linac for delivery of advanced electron beam therapy. It has previously been shown that electron beams collimated by an eMLC have very similar penumbra to those collimated by applicators and cutouts. Thus, manufacturing pa...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/58/16/5653

    authors: Eldib A,Jin L,Li J,Ma CM

    更新日期:2013-08-21 00:00:00

  • Female pelvic synthetic CT generation based on joint intensity and shape analysis.

    abstract::Using MRI for radiotherapy treatment planning and image guidance is appealing as it provides superior soft tissue information over CT scans and avoids possible systematic errors introduced by aligning MR to CT images. This study presents a method that generates Synthetic CT (MRCT) volumes by performing probabilistic t...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/62/8/2935

    authors: Liu L,Jolly S,Cao Y,Vineberg K,Fessler JA,Balter JM

    更新日期:2017-04-21 00:00:00

  • Monte Carlo verification of polymer gel dosimetry applied to radionuclide therapy: a phantom study.

    abstract::This study evaluates the dosimetric performance of the polymer gel dosimeter 'Methacrylic and Ascorbic acid in Gelatin, initiated by Copper' and its suitability for quality assurance and analysis of I-131-targeted radionuclide therapy dosimetry. Four batches of gel were manufactured in-house and sets of calibration vi...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/56/22/017

    authors: Gear JI,Charles-Edwards E,Partridge M,Flux GD

    更新日期:2011-11-21 00:00:00

  • Head scatter modelling for irregular field shaping and beam intensity modulation.

    abstract::Scattered radiation from within the treatment head can contribute significant dose to all parts of a radiotherapy treatment field. A multileaf collimator may be used to create an arbitrarily shaped field, and may also be used, under dynamic control, to modulate the beam intensity over the field. This method of intensi...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/42/9/006

    authors: Hounsell AR,Wilkinson JM

    更新日期:1997-09-01 00:00:00

  • Design optimization of multi-pinhole micro-SPECT configurations by signal detection tasks and system performance evaluations for mouse cardiac imaging.

    abstract::An optimized configuration of multi-pinhole aperture can improve the spatial resolution and the sensitivity of pinhole SPECT simultaneously. In this study, an optimization strategy of the multi-pinhole configuration with a small detector is proposed for mouse cardiac imaging. A 14 mm-diameter spherical field-of-view (...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/2/473

    authors: Lee MW,Lin WT,Chen YC

    更新日期:2015-01-21 00:00:00

  • A phantom for the testing and calibration of near infra-red spectrometers.

    abstract::This note describes a simple phantom which can be used to check the long term stability and accuracy of relative attenuation measurements made by near infra-red (NIR) spectrometers. The phantom has been calibrated, and the results of the calibration are shown to agree with theoretical predictions of the relative atten...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/39/9/015

    authors: Firbank M,Delpy DT

    更新日期:1994-09-01 00:00:00

  • Laboratory prototype for experimental validation of MR-guided radiofrequency head and neck hyperthermia.

    abstract::Clinical studies have established a strong benefit from adjuvant mild hyperthermia (HT) to radio- and chemotherapy for many tumor sites, including the head and neck (H&N). The recently developed HYPERcollar allows the application of local radiofrequency HT to tumors in the entire H&N. Treatment quality is optimized us...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/59/9/2139

    authors: Paulides MM,Bakker JF,Hofstetter LW,Numan WC,Pellicer R,Fiveland EW,Tarasek M,Houston GC,van Rhoon GC,Yeo DT,Kotek G

    更新日期:2014-05-07 00:00:00

  • Temperature simulations in tissue with a realistic computer generated vessel network.

    abstract::The practical use of a discrete vessel thermal model for hyperthermia treatment planning requires a number of choices with respect to the unknown part of the patient's vasculature. This work presents a study of the thermal effects of blood flow in a simple tissue geometry with a detailed artificial vessel network. The...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/45/4/317

    authors: Van Leeuwen GM,Kotte AN,Raaymakers BW,Lagendijk JJ

    更新日期:2000-04-01 00:00:00

  • Achieving reliable coincidence resolving time measurement of PET detectors using multichannel waveform digitizer based on DRS4 chip.

    abstract::Coincidence resolving time (CRT) is one of the most important physical-performance measures for positron emission tomography (PET), as reconstruction with accurate time-of-flight information enhances the lesion detectability in patient studies. Accordingly, various PET detector designs and high-performance front-end r...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aaf0bb

    authors: Park H,Lee S,Ko GB,Lee JS

    更新日期:2018-12-10 00:00:00

  • Optical attenuation characteristics of breast tissues at visible and near-infrared wavelengths.

    abstract::Optical experiments are described for measuring the attenuation characteristics of breast tissues at visible and near-infrared wavelengths. Total attenuation coefficients post mortem were measured directly in thin tissue sections. They are usually within the range from 10 to 30 mm-1, are rather higher in fat than in f...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/36/5/002

    authors: Key H,Davies ER,Jackson PC,Wells PN

    更新日期:1991-05-01 00:00:00

  • Linear dimension reduction of sequences of medical images: I. Optimal inner products.

    abstract::A general theory is presented for minimizing noise in linear dimension reduction of sequences of medical images when the factors and the covariance matrix and mean of the noise are given. A dimension reduction is optimal when all diagonal elements in the covariance matrix of the noise in the signal (factor) space are ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/40/11/010

    authors: Hermansen F,Lammertsma AA

    更新日期:1995-11-01 00:00:00

  • Radiofrequency and microwave dielectric properties of aqueous cryoprotectant agents: dimethyl sulphoxide and 2,3-butanediol.

    abstract::Earlier work on the dielectric properties of cryoprotectant agents is extended using a modified measuring cell and method of data reduction yielding results more efficiently over a temperature range from -75 to +25 degrees C at frequencies from 27 MHz to 3 GHz. Dimethyl sulphoxide and butanediol are investigated at lo...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/43/10/011

    authors: Evans S,bin Azeman A

    更新日期:1998-10-01 00:00:00

  • Simultaneous EEG-fMRI: evaluating the effect of the cabling configuration on the gradient artefact.

    abstract::EEG recordings made in combined EEG-fMRI studies are corrupted by gradient artefacts (GAs) resulting from the interaction of the EEG system with the time-varying magnetic field gradients used in MRI. The dominant contribution to the GA arises from interaction with the leads of the EEG cap and the human head, but artef...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/12/N241

    authors: Chowdhury ME,Mullinger KJ,Bowtell R

    更新日期:2015-06-21 00:00:00

  • Measurement of image contrast using diffraction enhanced imaging.

    abstract::Refraction contrast of simple objects obtained using diffraction enhanced imaging (DEI) was studied and compared to conventional radiographic contrast. Lucite cylinders and nylon wires were imaged using monochromatic synchrotron radiation at the National Synchrotron Light Source (http://nslsweb. nsls.bnl.gov/nsls/Defa...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/48/3/304

    authors: Kiss MZ,Sayers DE,Zhong Z

    更新日期:2003-02-07 00:00:00

  • Detour factors in water and plastic phantoms and their use for range and depth scaling in electron-beam dosimetry.

    abstract::Average penetration depths and detour factors of 1-50 MeV electrons in water and plastic materials have been computed by means of analytical calculation, within the continuous-slowing-down approximation and including multiple scattering, and using the Monte Carlo codes ITS and PENELOPE. Results are compared to detour ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/41/7/004

    authors: Fernández-Varea JM,Andreo P,Tabata T

    更新日期:1996-07-01 00:00:00

  • Modifying proton fluence spectra to generate spread-out Bragg peaks with laser accelerated proton beams.

    abstract::Currently, energy spectra of laser accelerated proton beams are far from being monoenergetic. For their application in radiation therapy, energy selection systems using magnetic fields have been proposed to single out particles with the desired energy. These systems allow the choice of protons between a lowest and a h...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/54/19/N04

    authors: Schell S,Wilkens JJ

    更新日期:2009-10-07 00:00:00

  • Modelling the temporal region in patients with temporal lobe epilepsy.

    abstract::EEG interictal epileptiform discharges in temporal lobe epilepsy are associated with magnetic fields. The maxima of magnetic spikes recorded over the spherical portions of the head appear fairly symmetric, whereas those over the lower temporal region often have irregular shapes. Furthermore, their magnitude is often u...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/32/1/009

    authors: Rose DF,Sato S,Smith PD,White J

    更新日期:1987-01-01 00:00:00