Abstract:
:The goal of this study was to determine the quantitative accuracy of our OSEM-APDI reconstruction method based on SPECT/CT imaging for Tc-99m, In-111, I-123, and I-131 isotopes. Phantom studies were performed on a SPECT/low-dose multislice CT system (Infinia-Hawkeye-4 slice, GE Healthcare) using clinical acquisition protocols. Two radioactive sources were centrally and peripherally placed inside an anthropometric Thorax phantom filled with non-radioactive water. Corrections for attenuation, scatter, collimator blurring and collimator septal penetration were applied and their contribution to the overall accuracy of the reconstruction was evaluated. Reconstruction with the most comprehensive set of corrections resulted in activity estimation with error levels of 3-5% for all the isotopes.
journal_name
Phys Med Bioljournal_title
Physics in medicine and biologyauthors
Shcherbinin S,Celler A,Belhocine T,Vanderwerf R,Driedger Adoi
10.1088/0031-9155/53/17/009subject
Has Abstractpub_date
2008-09-07 00:00:00pages
4595-604issue
17eissn
0031-9155issn
1361-6560pii
S0031-9155(08)77235-Xjournal_volume
53pub_type
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