Determination of fractional flow reserve (FFR) based on scaling laws: a simulation study.

abstract：:Positron emission tomography (PET) has become an important modality in medical and molecular imaging. However, in most PET applications, the resolution is still mainly limited by the physical crystal sizes or the detector's intrinsic spatial resolution. To achieve images with better spatial resolution in a central reg...

journal_title：Physics in medicine and biology

authors： Li Y,Matej S,Karp JS,Metzler SD

更新日期：2015-01-21 00:00:00

abstract：:This work studies the effect of age on lung dose commitments arising from the inhalation of an atmosphere containing radionuclides of varying half-lives and physical sizes. This dependence is significant in many cases, approaching a ratio of 2 in several instances when the maximum dose at a given age is compared with ...

journal_title：Physics in medicine and biology

authors： Crawford DJ

更新日期：1982-04-01 00:00:00

abstract：:An open-ended coaxial probe is often used for investigating the dielectric properties of biological tissues. The present study indicates that in addition to the probe size, the penetration of the electromagnetic (EM) fields of an open-ended coaxial probe in contact with the skin is dependent on the applied frequency b...

journal_title：Physics in medicine and biology

authors： Alanen E,Lahtinen T,Nuutinen J

更新日期：1999-07-01 00:00:00

abstract：:Dose to water (Dw) determination in clinical high-energy photon beams with ionization chambers calibrated in terms of absorbed dose to water has been proposed as an alternative to ionization chamber dosimetry based on air kerma calibrations. Dw in the clinical beam is derived using a kappaQ factor that scales the abso...

journal_title：Physics in medicine and biology

authors： Palmans H,Mondelaers W,Thierens H

更新日期：1999-03-01 00:00:00

abstract：:The aim of this work is to evaluate dosimetric accuracy of a new treatment modality, HybridArc, in iPlan RT Dose 4.5 (BrainLAB, Feldkirchen, Germany) using a four-dimensional diode array (ArcCHECK, Sun Nuclear Corporation, Melbourne, USA). HybridArc is able to enhance dynamic conformal arcs with inversely planned elem...

journal_title：Physics in medicine and biology

authors： Petoukhova AL,van Egmond J,Eenink MG,Wiggenraad RG,van Santvoort JP

更新日期：2011-08-21 00:00:00

abstract：:This study presents a combined small animal holding fixture system, termed a 'bridge capsule', which provides for small animal re-fixation with positional reproducibility. This system comprises separate holding fixtures for the head and lower body and a connecting part to a gas anesthesia system. A mouse is fixed in p...

journal_title：Physics in medicine and biology

authors： Kokuryo D,Kimura Y,Obata T,Yamaya T,Kawamura K,Zhang MR,Kanno I,Aoki I

更新日期：2010-07-21 00:00:00

abstract：:We assume that the data bits of a pixel in digital images can be divided into signal and noise bits. The signal bits occupy the most significant part of the pixel and the noise bits the least significant part. The signal part of each pixel are correlated while the noise parts are uncorrelated. Two statistical methods,...

journal_title：Physics in medicine and biology

authors： Chuang KS,Huang HK

更新日期：1992-02-01 00:00:00

abstract：:New definitions of the absorbed dose conversion factors Clambda and CE are proposed. The absorbed dose in water is given by the product of absorbed dose conversion factor, exposure calibration factor, ionisation chamber reading, cap displacement correction factor and perturbation correction factor. At exposure calibra...

journal_title：Physics in medicine and biology

authors： Shiragai A

更新日期：1978-03-01 00:00:00

abstract：:A classical trajectory model has been used to predict total cross sections of single and double ionizing processes (including capture processes) for several ion-biological molecule collisional systems in the intermediate and high energy range. In this work, the systems studied are water, adenine or cytosine targets io...

journal_title：Physics in medicine and biology

authors： Abbas I,Champion C,Zarour B,Lasri B,Hanssen J

更新日期：2008-02-21 00:00:00

abstract：:Ultrasoft x-rays of 0.3-5 keV have provided a unique tool for the investigation of intracellular mechanisms of radiation action in biological organisms, including mammalian cells. However, their use presents unique practical problems in dosimetry and experimental design. Detailed interpretation of the biological resul...

journal_title：Physics in medicine and biology

authors： Hoshi M,Goodhead DT,Brenner DJ,Bance DA,Chmielewski JJ,Paciotti MA,Bradbury JN

更新日期：1985-10-01 00:00:00

abstract：:We have developed an impedance magnetocardiogram (IMCG) system to detect the change of magnetic field corresponding to changes in blood volume in the heart. A low magnetic field from the electrical activity of the human heart--the so-called magnetocardiogram (MCG)--can be simultaneously detected by using this system. ...

journal_title：Physics in medicine and biology

authors： Kandori A,Miyashita T,Suzuki D,Yokosawa K,Tsukada K

更新日期：2001-02-01 00:00:00

abstract：:Time-of-flight (TOF) positron emission tomography (PET) technology has recently regained popularity in clinical PET studies for improving image quality and lesion detectability. Using TOF information, the spatial location of annihilation events is confined to a number of image voxels along each line of response, there...

journal_title：Physics in medicine and biology

authors： Mehranian A,Kotasidis F,Zaidi H

更新日期：2016-02-07 00:00:00

abstract：:In critical organ in vivo x-ray dosimetry, the relative contaminating electron contribution to the total dose and total detector response outside the field will be different to the corresponding contributions at the central axis detector calibration position, mainly due to the effects of shielding in the linear accele...

journal_title：Physics in medicine and biology

authors： Edwards CR,Mountford PJ,Moloney AJ

更新日期：2006-12-21 00:00:00

abstract：:At present, there exists few openly available methods for evaluation of simultaneous segmentation and registration algorithms. These methods allow for a combination of both techniques to track the tumor in complex settings such as adaptive radiotherapy. We have produced a quality assurance platform for evaluating this...

journal_title：Physics in medicine and biology

authors： Markel D,Levesque I,Larkin J,Léger P,El Naqa I

更新日期：2016-10-07 00:00:00

abstract：:The convergence rates of the fast Padé transform (FPT) and the fast Fourier transform (FFT) are compared. These two estimators are used to process a time-signal encoded at 4 T by means of one-dimensional magnetic resonance spectroscopy (MRS) for healthy human brain. It is found systematically that at any level of trun...

journal_title：Physics in medicine and biology

authors： Belkić D,Belkić K

更新日期：2005-09-21 00:00:00

abstract：:The in vivo electric conductivity (σ) values of tissue are essential for accurate electromagnetic simulations and specific absorption rate (SAR) assessment for applications such as thermal dose computations in hyperthermia. Currently used σ-values are mostly based on ex vivo measurements. In this study the conductivit...

journal_title：Physics in medicine and biology

authors： Balidemaj E,de Boer P,van Lier AL,Remis RF,Stalpers LJ,Westerveld GH,Nederveen AJ,van den Berg CA,Crezee J

更新日期：2016-02-21 00:00:00

abstract：:Computational simulations, such as Monte Carlo track structure simulations, offer a powerful tool for quantitatively investigating radiation interactions within cells. The modelling of the spatial distribution of energy deposition events as well as diffusion of chemical free radical species, within realistic biologica...

journal_title：Physics in medicine and biology

authors： McNamara AL,Ramos-Méndez J,Perl J,Held K,Dominguez N,Moreno E,Henthorn NT,Kirkby KJ,Meylan S,Villagrasa C,Incerti S,Faddegon B,Paganetti H,Schuemann J

更新日期：2018-09-06 00:00:00

abstract：:This study investigates the oxygen mass transport in the region around the human carotid bifurcation, particularly addressing the effects of bifurcation geometry and pulsatile blood flow on the oxygen transport between the blood flow and artery wall tissue, coupled with the metabolic oxygen consumption and oxygen diff...

journal_title：Physics in medicine and biology

authors： Tada S

更新日期：2010-07-21 00:00:00

abstract：:Dose measurements following 10 min irradiations with a portable x-ray fluorescence spectrometer composed of a miniature x-ray tube and a silicon PiN diode detector were performed using thermoluminescent dosimeters consisting of LiF:Mg,Ti chips of 3 mm diameter and 0.4 mm thickness. The table-top setup of the spectrome...

journal_title：Physics in medicine and biology

authors： Gherase MR,Mader JE,Fleming DE

更新日期：2010-09-21 00:00:00

abstract：:This paper presents a computerized method for the selection of an irregular region of interest (ROI) in broadband ultrasound attenuation (BUA) images. A region growing algorithm searches an initial region in the posterior part of the calcaneus until the pixel with the lowest attenuation value is found; this is the sta...

journal_title：Physics in medicine and biology

authors： Damilakis J,Stratakis J,Perisinakis K,Gourtsoyiannis N

更新日期：2002-01-21 00:00:00

abstract：:In carbon-ion radiotherapy, single-beam delivery each day in alternate directions has been common practice for efficient operation, taking advantage of the Bragg peak and the relative biological effectiveness (RBE) for uniform dose conformation to a tumor. Treatments are usually fractionated and treatment plans are ev...

journal_title：Physics in medicine and biology

authors： Kanematsu N,Inaniwa T

更新日期：2017-02-07 00:00:00

abstract：:Radiochromic leuco crystal violet (LCV) micelle gel dosimeters are promising three-dimensional radiation dosimeters because of their spatial stability and suitability for optical readout. The effects of surfactant type and surfactant concentration on dose sensitivity of LCV micelle gels are tested, demonstrating that ...

journal_title：Physics in medicine and biology

authors： Nasr AT,Alexander K,Schreiner LJ,McAuley KB

更新日期：2015-06-21 00:00:00

abstract：:Projection and backprojection are operations that arise frequently in tomographic imaging. Recently, we proposed a new method for projection and backprojection, which we call distance-driven, and that offers low arithmetic cost and a highly sequential memory access pattern. Furthermore, distance-driven projection and ...

journal_title：Physics in medicine and biology

authors： De Man B,Basu S

更新日期：2004-06-07 00:00:00

abstract：:We present a new method for automated characterization of atherosclerotic plaque composition in ex vivo MRI. It uses MRI intensities as well as four other types of features: smoothed, gradient magnitude and Laplacian images at several scales, and the distances to the lumen and outer vessel wall. The ground truth for f...

journal_title：Physics in medicine and biology

authors： van Engelen A,Niessen WJ,Klein S,Groen HC,Verhagen HJ,Wentzel JJ,van der Lugt A,de Bruijne M

更新日期：2012-01-07 00:00:00

abstract：:New organ dose conversion coefficients for coronary angiographic interventions are presented, as well as dose distributions and resulting maximal local dose conversion coefficients in the relevant organs. For the Monte Carlo based simulations, voxel models of the human anatomy were employed which represent the average...

journal_title：Physics in medicine and biology

authors： Schlattl H,Zankl M,Hausleiter J,Hoeschen C

更新日期：2007-08-07 00:00:00

abstract：:Although not as widespread as Ir-192, Co-60 is also available on afterloading equipment devoted to high dose rate brachytherapy, mainly addressed to the treatment of gynaecological lesions. The purpose of this study is to obtain the dosimetric parameters of the Co-60 source used by the BEBIG MultiSource remote afterlo...

journal_title：Physics in medicine and biology

authors： Ballester F,Granero D,Pérez-Calatayud J,Casal E,Agramunt S,Cases R

更新日期：2005-11-07 00:00:00

abstract：:Many models exist for predicting toxicities based on dose-volume histograms (DVHs) or dose-surface histograms (DSHs). This approach has several drawbacks as firstly the reduction of the dose distribution to a histogram results in the loss of spatial information and secondly the bins of the histograms are highly correl...

journal_title：Physics in medicine and biology

authors： Buettner F,Gulliford SL,Webb S,Partridge M

更新日期：2011-04-07 00:00:00

abstract：:In order to optimize external-beam conformal radiotherapy, patient movement during treatment must be minimized. For treatment on the upper torso, the target organs are known to move substantially due to patient respiration. This paper deals with the technical aspects of gating the radiotherapy beam synchronously with ...

journal_title：Physics in medicine and biology

authors： Kubo HD,Hill BC

更新日期：1996-01-01 00:00:00

abstract：:Although physical metrics can objectively characterize computed tomography (CT) image quality, quantitative approaches to predict human observer performance are more accurate and clinically relevant. This study compared a modified channelized Hotelling model observer (CHO) with human observers in a shape discriminatio...

journal_title：Physics in medicine and biology

authors： Zhang Y,Leng S,Yu L,Carter RE,McCollough CH

更新日期：2014-07-07 00:00:00

abstract：:Using Cherenkov radiation in positron emission tomography (PET) has the potential to improve the time of flight (TOF) resolution and reduce the cost of detectors. In previous studies promising TOF results were achieved when lead fluoride (PbF2) crystals were used instead of a scintillator. In this work, a whole-body P...

journal_title：Physics in medicine and biology

authors： Consuegra D,Korpar S,Križan P,Pestotnik R,Razdevšek G,Dolenec R

更新日期：2020-03-06 00:00:00