Leuco-crystal-violet micelle gel dosimeters: I. Influence of recipe components and potential sensitizers.

abstract：:Online proton range/dose verification based on measurements of proton-induced positron emitters is a promising strategy for quality assurance in proton therapy. Because of the nonlinear correlation between the dose distribution and the activity distribution of positron emitters, we aim to establish their relationship ...

journal_title：Physics in medicine and biology

authors： Liu C,Li Z,Hu W,Xing L,Peng H

更新日期：2019-09-04 00:00:00

abstract：:The dose-calculation accuracy of the tomotherapy Hi-Art II(R) (Tomotherapy, Inc., Madison, WI) treatment planning system (TPS) in the presence of low-density lung media was investigated. In this evaluation, a custom-designed heterogeneous phantom mimicking the mediastinum geometry was used. Gammex LN300 and balsa wood...

journal_title：Physics in medicine and biology

authors： Chaudhari SR,Pechenaya OL,Goddu SM,Mutic S,Rangaraj D,Bradley JD,Low D

更新日期：2009-04-21 00:00:00

abstract：:All radiation therapy treatment planning relies on accurate dose calculation. Uncertainties in dosimetric prediction can significantly degrade an otherwise optimal plan. In this work, we introduce a robust optimization method which handles dosimetric errors and warrants for high-quality IMRT plans. Unlike other dose e...

journal_title：Physics in medicine and biology

authors： Nohadani O,Seco J,Martin BC,Bortfeld T

更新日期：2009-06-07 00:00:00

abstract：:Indocyanine green (ICG) is a near-infrared dye that has the potential to be used as a tracer for the minimally invasive measurement of cerebral blood flow (CBF). In order to examine the technique, the arterial and cerebral concentrations of ICG were measured in newborn piglets during the bolus passage of ICG at normoc...

journal_title：Physics in medicine and biology

authors： Springett R,Sakata Y,Delpy DT

更新日期：2001-08-01 00:00:00

abstract：:Changes in the relative biological effectiveness (RBE) of the radiation-induced cell killing of human salivary glands (HSG) were assessed along the Bragg peak of a 60 MeV clinical proton beam by means of coupling biophysical models with the results of Monte Carlo radiation transport simulations and experimental measur...

journal_title：Physics in medicine and biology

authors： Parisi A,Olko P,Swakoń J,Horwacik T,Jabłoński H,Malinowski L,Nowak T,Struelens L,Vanhavere F

更新日期：2020-01-10 00:00:00

abstract：:Lung 4D computed tomography (4D-CT), which is a time-resolved CT data acquisition, performs an important role in explicitly including respiratory motion in treatment planning and delivery. However, the radiation dose is usually reduced at the expense of inter-slice spatial resolution to minimize radiation-related heal...

journal_title：Physics in medicine and biology

authors： Fang S,Wang H,Liu Y,Zhang M,Yang W,Feng Q,Chen W,Zhang Y

更新日期：2017-10-03 00:00:00

abstract：:Measurements of lung nodule volume with multi-detector computed tomography (MDCT) have been shown to be more accurate and precise compared to conventional lower dimensional measurements. Quantifying the size of lesions is potentially more difficult when the object-to-background contrast is low as with lesions in the l...

journal_title：Physics in medicine and biology

authors： Li Q,Gavrielides MA,Zeng R,Myers KJ,Sahiner B,Petrick N

更新日期：2015-01-21 00:00:00

abstract：:Absorbed dose values were determined under the reference conditions in a phantom irradiated by high-energy photon beams with quality varying between 60Co gamma rays and 25 MV X-rays, using four commonly employed types of ionisation chamber. The ionisation chamber readings were converted to absorbed dose values applyin...

journal_title：Physics in medicine and biology

authors： Mijnheer BJ,Wittkämper FW

更新日期：1986-04-01 00:00:00

abstract：:Arc-therapy is a dose delivery technique regularly applied in photon radiation therapy, and is currently subject of great interest for proton therapy as well. In this technique, proton beams are aimed at a tumor from different continuous ranges of incident directions (so called "arcs"). This technique can potentially ...

journal_title：Physics in medicine and biology

authors： Nesteruk KP,Bolsi A,Lomax AJ,Meer D,van de Water S,Schippers JM

更新日期：2021-01-26 00:00:00

abstract：:The amount of silica in the human lung may be estimated by measurement of silicon using in vivo neutron activation analysis. A pulsed, fast neutron beam, produced with a 2 MV Van de Graaff generator using the 2H + 2H reaction, was used to irradiate a Si-doped chest phantom in order to determine minimum detection limit...

journal_title：Physics in medicine and biology

authors： Kacperek A,Ryde SJ,Evans CJ,Dutton J,Morgan WD,Sivyer A

更新日期：1993-06-01 00:00:00

abstract：:Image-guided radiation therapy using implanted fiducial markers is a common solution for prostate localization to improve targeting accuracy. However, fiducials that are typically used for conventional photon radiotherapy cause large dose perturbations in patients who receive proton radiotherapy. A proposed solution h...

journal_title：Physics in medicine and biology

authors： Cheung J,Kudchadker RJ,Zhu XR,Lee AK,Newhauser WD

更新日期：2010-12-07 00:00:00

abstract：:The aim of this paper is to determine the dosimetric impact of trace elements in human tissues for low-energy photon sources used in brachytherapy. Monte Carlo dose calculations were used to investigate the dosimetric effect of trace elements present in normal or cancerous human tissues. The effect of individual trace...

journal_title：Physics in medicine and biology

authors： White SA,Landry G,van Gils F,Verhaegen F,Reniers B

更新日期：2012-06-07 00:00:00

abstract：:Two detectors for fast two-dimensional (2D) and quasi-three-dimensional (quasi-3D) verification of the dose delivered by radiotherapy beams have been developed at University and Istituto Nazionale di Fisica Nucleare (INFN) of Torino. The Magic Cube is a stack of strip-segmented ionization chambers interleaved with wat...

journal_title：Physics in medicine and biology

authors： Cirio R,Garelli E,Schulte R,Amerio S,Boriano A,Bourhaleb F,Coutrakon G,Donetti M,Giordanengo S,Koss P,Madon E,Marchetto F,Nastasi U,Peroni C,Santuari D,Sardo A,Scielzo G,Stasi M,Trevisiol E

更新日期：2004-08-21 00:00:00

abstract：:A method for quantifying the tissue sodium concentration (TSC) in the rat brain from ²³Na-MR images was developed. TSC is known to change in a variety of common human diseases and holds considerable potential to contribute to their study; however, its accurate measurement in small laboratory animals has been hindered ...

journal_title：Physics in medicine and biology

authors： Wetterling F,Tabbert M,Junge S,Gallagher L,Macrae IM,Fagan AJ

更新日期：2010-12-21 00:00:00

abstract：:In this work, a procedure, based on Monte Carlo techniques, to analyse the effect on the tumour control probability of the time interval between surgery and postoperative radiotherapy is presented. The approach includes the tumour growth as well as the survival of tumour cells undergoing fractionated radiotherapy. Bot...

journal_title：Physics in medicine and biology

authors： Al-Dweri FM,Guirado D,Lallena AM,Pedraza V

更新日期：2004-07-07 00:00:00

abstract：:We examined the reasons for the reduction in response of a multidetector radiation counting system when operated at high count-rates and established a convenient method of correction which is accurate to within +/- 1% up to 0-6 X 10(5) counts per second. In its application the method uses the observed count-rates from...

journal_title：Physics in medicine and biology

authors： Oxby CB,Oldroyd B,Appleby DB

更新日期：1976-01-01 00:00:00

abstract：:To investigate the profile measurement capabilities of an IBA-Dosimetry scintillation detector and to assess its feasibility for determining the low-intensity tails of pencil-beam scanning spots, the responses of the scintillation detector and Gafchromic EBT2 film to a 115 MeV proton spot were measured in-air at the i...

journal_title：Physics in medicine and biology

authors： Lin L,Ainsley CG,Mertens T,De Wilde O,Talla PT,McDonough JE

更新日期：2013-06-21 00:00:00

abstract：:The objective of this study was to be able to distinguish between healthy skin tissue and malignant ones, furthermore determining a unique pattern of roughness for each skin lesion by microtopographic analysis of the skin surface of Mexican patients during the period from April to October 2002. The standard technique ...

journal_title：Physics in medicine and biology

authors： del Carmen López Pacheco M,da Cunha Martins-Costa MF,Zapata AJ,Cherit JD,Gallegos ER

更新日期：2005-12-07 00:00:00

abstract：:Time-of-flight (TOF) positron emission tomography (PET) technology has recently regained popularity in clinical PET studies for improving image quality and lesion detectability. Using TOF information, the spatial location of annihilation events is confined to a number of image voxels along each line of response, there...

journal_title：Physics in medicine and biology

authors： Mehranian A,Kotasidis F,Zaidi H

更新日期：2016-02-07 00:00:00

abstract：:We used a real-skull phantom head to investigate the performances of representative methods for EEG source localization when considering various head models. We describe several experiments using a montage with current sources located at multiple positions and orientations inside a human skull filled with a conductive...

journal_title：Physics in medicine and biology

authors： Baillet S,Riera JJ,Marin G,Mangin JF,Aubert J,Garnero L

更新日期：2001-01-01 00:00:00

abstract：:Ankylosing spondylitis is a disease characterized by abnormal bone formation (syndesmophyte) at the margins of inter-vertebral disc spaces. Syndesmophyte growth is currently typically monitored by the visual inspection of radiographs. The limitations inherent to the modality (2D projection of a 3D object) and rater (q...

journal_title：Physics in medicine and biology

authors： Tan S,Yao J,Yao L,Ward MM

更新日期：2012-07-21 00:00:00

abstract：:A common dose-saving technique used in modern CT devices is automatic tube current modulation (TCM), which was originally designed to also reduce the dose in paediatric CT patients. In order to be able to deduce detailed organ doses of paediatric models, dose conversion coefficients normalized to CTDI(vol) for an eigh...

journal_title：Physics in medicine and biology

authors： Schlattl H,Zankl M,Becker J,Hoeschen C

更新日期：2012-10-21 00:00:00

abstract：:The measurement of output factors (OF) for the small photon beams generated by Leksell Gamma Knife® (LGK) radiotherapy units is a challenge for the physicist due to the under or over estimation of these factors by a vast majority of the detectors commercially available. Output correction factors, introduced in the int...

journal_title：Physics in medicine and biology

authors： Benmakhlouf H,Johansson J,Paddick I,Andreo P

更新日期：2015-05-21 00:00:00

abstract：:Radionuclides which decay by electron capture accompanied by Auger electron cascades, or by beta emission are thought to be excessively damaging when incorporated into the molecular structure of mammalian cell nuclei and thereby pose a radiation hazard which is not assessable by conventional dosimetry. Survival data, ...

journal_title：Physics in medicine and biology

authors： Younis AR,Watt DE

更新日期：1989-07-01 00:00:00

abstract：:Average cross-sections for inactivation of dry ribonuclease by H, He and N projectiles with energies between 100 eV and 10 keV are presented. The trend of the damage cross-sections with particle energy is consistent with the trend of the molecular quasi-elastic scattering and ionization cross-sections. A tentative rad...

journal_title：Physics in medicine and biology

authors： Watt DE,Sutcliffe JF

更新日期：1975-11-01 00:00:00

abstract：:With high-dose administration of (90)Y labeled antibodies, it is possible to image (90)Y without an admixture of (111)In. We have earlier shown that it is possible to perform quantitative (90)Y bremsstrahlung SPECT for dosimetry purposes with reasonable accuracy. However, whole-body (WB) activity quantification with t...

journal_title：Physics in medicine and biology

authors： Minarik D,Ljungberg M,Segars P,Gleisner KS

更新日期：2009-10-07 00:00:00

abstract：:IMRT optimization is an iterative process in which many dose calculations may be necessary. A fast and accurate dose calculation engine is essential for the optimization program to converge to a reliable solution in a reasonable time. Previously we developed a fast dose calculation method for IMRT optimization based o...

journal_title：Physics in medicine and biology

authors： Wu Q

更新日期：2004-10-07 00:00:00

abstract：:The Jacobian of the deformation field of elastic registration between images taken during radiotherapy is a measure of inter-fraction local deformation. The histogram of the Jacobian values (Jac) within an organ was introduced (JVH-Jacobian-volume-histogram) and first applied in quantifying parotid shrinkage. MVCTs of...

journal_title：Physics in medicine and biology

authors： Fiorino C,Maggiulli E,Broggi S,Liberini S,Cattaneo GM,Dell'oca I,Faggiano E,Di Muzio N,Calandrino R,Rizzo G

更新日期：2011-06-07 00:00:00

abstract：:Diffuse optical tomography is an imaging technique whereby spatial maps of absorption and scattering coefficients are derived from the characteristics of multiply scattered light transmitted through the object. The system described here used four intensity-modulated light sources and measurements of the intensity and ...

journal_title：Physics in medicine and biology

authors： Pogue BW,Patterson MS,Jiang H,Paulsen KD

更新日期：1995-10-01 00:00:00

abstract：:Avoiding toxicities in radiotherapy requires the knowledge of tolerable organ doses. For new, experimental fractionation schemes (e.g. hypofractionation) these are typically derived from traditional schedules using the biologically effective dose (BED) model. In this report we investigate the difficulties of establish...

journal_title：Physics in medicine and biology

authors： Perkó Z,Bortfeld T,Hong T,Wolfgang J,Unkelbach J

更新日期：2018-02-05 00:00:00