Initial assessment of a simple system for frequency domain diffuse optical tomography.

abstract：:The relative biological effectiveness (RBE) of protons varies with multiple physical and biological factors. Phenomenological RBE models have been developed to include such factors in the estimation of a variable RBE, in contrast to the clinically applied constant RBE of 1.1. In this study, eleven published phenomenol...

journal_title：Physics in medicine and biology

authors： Rørvik E,Fjæra LF,Dahle TJ,Dale JE,Engeseth GM,Stokkevåg CH,Thörnqvist S,Ytre-Hauge KS

更新日期：2018-09-13 00:00:00

abstract：:It is difficult to test near-infrared spectrophotometry instruments in vivo. Therefore we constructed a liquid phantom which mimics the neonatal head. It consists of a spherical 3.5 mm thick layer of silicone rubber simulating skin and bone and a 0.5 mm thick clear layer of polypropylene imitating cerebrospinal fluid....

journal_title：Physics in medicine and biology

authors： Wolf M,Keel M,Dietz V,von Siebenthal K,Bucher HU,Baenziger O

更新日期：1999-07-01 00:00:00

abstract：:Intensity modulated particle therapy (IMPT) with carbon ions can generate highly conformal treatment plans; however, IMPT is limited in robustness against range and positioning uncertainty. This is particularly true for moving targets, even though all motion states of a 4DCT are considered in 4D-IMPT. Here, we expand ...

journal_title：Physics in medicine and biology

authors： Wolf M,Anderle K,Durante M,Graeff C

更新日期：2020-11-06 00:00:00

abstract：:The first trimester fetal ultrasound scan is important to confirm fetal viability, to estimate the gestational age of the fetus, and to detect fetal anomalies early in pregnancy. First trimester ultrasound images have a different appearance than for the second trimester scan, reflecting the different stage of fetal de...

journal_title：Physics in medicine and biology

authors： Ryou H,Yaqub M,Cavallaro A,Papageorghiou AT,Alison Noble J

更新日期：2019-09-17 00:00:00

abstract：:The purpose of this study is to explain the unplanned longitudinal dose modulations that appear in helical tomotherapy (HT) dose distributions in the presence of irregular patient breathing. This explanation is developed by the use of longitudinal (1D) simulations of mock and surrogate data and tested with a fully 4D ...

journal_title：Physics in medicine and biology

authors： Kissick MW,Flynn RT,Westerly DC,Hoban PW,Mo X,Soisson ET,McCall KC,Mackie TR,Jeraj R

更新日期：2008-09-21 00:00:00

abstract：:X-ray fluorescence computed tomography (XFCT) is a relatively new synchrotron-based imaging modality aiming at reconstructing the distribution of nonradiative elements within a sample irradiated with high-intensity monochromatic x-rays. In a recent paper La Rivière (2004 Phys. Med. Biol. 49 2391-405) presented an appr...

journal_title：Physics in medicine and biology

authors： Miqueles EX,De Pierro AR

更新日期：2010-02-21 00:00:00

abstract：:Stopping power data for protons in tissue-equivalent gas (64.4% CH4 + 32.4% CO2 + 3.2% N2, partial pressures) were derived from experimentally determined ranges and from differential ionisation distributions using the differential energy required per ion pair formed to convert ionisation to energy loss. The proton ene...

journal_title：Physics in medicine and biology

authors： Waibel E,Willems G

更新日期：1987-03-01 00:00:00

abstract：:EEG recordings made in combined EEG-fMRI studies are corrupted by gradient artefacts (GAs) resulting from the interaction of the EEG system with the time-varying magnetic field gradients used in MRI. The dominant contribution to the GA arises from interaction with the leads of the EEG cap and the human head, but artef...

journal_title：Physics in medicine and biology

authors： Chowdhury ME,Mullinger KJ,Bowtell R

更新日期：2015-06-21 00:00:00

abstract：:Clinical cerebral blood flow (CBF) maps generated through dynamic- susceptibility contrast (DSC) magnetic resonance (MR) perfusion imaging are currently cross-calibrated with PET studies. The cross-calibration is achieved by rescaling the MR CBF values so that normal white matter CBF corresponds to 22 ml/100 g/min. Ex...

journal_title：Physics in medicine and biology

authors： Chen JJ,Frayne R,Smith MR

更新日期：2005-03-21 00:00:00

abstract：:All dosimetry protocols recommend the use of plane-parallel chambers for dose determination in electron beams with energies below 10-15 MeV. The protocols have assumed chamber perturbation effects to be negligible. The new AAPM Protocol (TG39) includes a cavity replacement factor prepl that differs from unity for some...

journal_title：Physics in medicine and biology

authors： Nilsson B,Montelius A,Andreo P

更新日期：1996-04-01 00:00:00

abstract：:The Monte Carlo method is the most accurate method for radiotherapy dose calculations, if used correctly. However, any Monte Carlo dose calculation is burdened with statistical noise. In this paper, denoising of Monte Carlo dose distributions with a three-dimensional adaptive anisotropic diffusion method was investiga...

journal_title：Physics in medicine and biology

authors： Miao B,Jeraj R,Bao S,Mackie TR

更新日期：2003-09-07 00:00:00

abstract：:Nanocarriers offer a promising approach to significantly improve therapeutic delivery to solid tumors as well as limit the side effects associated with anti-cancer agents. However, their relatively large size can negatively affect their ability to efficiently penetrate into more interior tumor regions, ultimately redu...

journal_title：Physics in medicine and biology

authors： Mohammadabadi A,Huynh RN,Wadajkar AS,Lapidus RG,Kim AJ,Raub CB,Frenkel V

更新日期：2020-06-22 00:00:00

abstract：:Respiratory gating can reduce the apparent respiratory motion during imaging and treatment; however, residual motion within the gating window remains. Respiratory training can improve respiratory reproducibility and, therefore, the efficacy of respiratory-gated radiotherapy. This study was conducted to determine wheth...

journal_title：Physics in medicine and biology

authors： George R,Ramakrishnan V,Siebers JV,Chung TD,Keall PJ

更新日期：2006-10-21 00:00:00

abstract：:The objective of this paper is to evaluate an iterative maximum likelihood (ML) cone-beam computed tomography (CBCT) reconstruction with total variation (TV) regularization with respect to the robustness of the algorithm due to data inconsistencies. Three different and (for clinical application) typical classes of err...

journal_title：Physics in medicine and biology

authors： Stsepankou D,Arns A,Ng SK,Zygmanski P,Hesser J

更新日期：2012-10-07 00:00:00

abstract：:We show how the spectral imaging framework should be modified to account for a high fraction of Compton interactions in low Z detector materials such as silicon. Using this framework, where deposited energies differ from actual photon energies, we compare the performance of a silicon strip detector, including the infl...

journal_title：Physics in medicine and biology

authors： Bornefalk H,Danielsson M

更新日期：2010-04-07 00:00:00

abstract：:We study the spatial distributions of beta(+)-activity produced by therapeutic beams of (3)He and (12)C ions in various tissue-like materials. The calculations were performed within a Monte Carlo model for heavy-ion therapy (MCHIT) based on the GEANT4 toolkit. The contributions from positron-emitting nuclei with T(1/2...

journal_title：Physics in medicine and biology

authors： Pshenichnov I,Larionov A,Mishustin I,Greiner W

更新日期：2007-12-21 00:00:00

abstract：:Breast-conserving surgery is a standard option for the treatment of patients with early-stage breast cancer. This form of surgery may result in incomplete excision of the tumor. Iodine-125 labeled titanium seeds are currently used in clinical practice to reduce the number of incomplete excisions. It seems likely that ...

journal_title：Physics in medicine and biology

authors： Arsenali B,de Jong HW,Viergever MA,Dickerscheid DB,Beijst C,Gilhuijs KG

更新日期：2015-10-07 00:00:00

abstract：:The energy dependence of the luminance ratio due to scattered and primary radiation has been determined for four types of X-ray intensifying screens. A water phantom of 30 cm X 30 cm X 20 cm was used as the scattering medium. Ten narrow band X-ray spectra were used as incident radiation: the mean energies of these spe...

journal_title：Physics in medicine and biology

authors： Koedooder K,Venema HW

更新日期：1984-10-01 00:00:00

abstract：:This paper concerns the robustness of discrete wavelet transform (DWT) compression in terahertz pulsed imaging (TPI). TPI datasets consist of terahertz time-domain series which are sampled at each 'pixel' of the image, leading to file sizes which are typically of the order of several megabytes (MB) per image. This mak...

journal_title：Physics in medicine and biology

authors： Handley JW,Fitzgerald AJ,Berry E,Boyle RD

更新日期：2002-11-07 00:00:00

abstract：:The probability of a photon (x-ray, gamma-ray, bremsstrahlung, etc) of a given energy E undergoing absorption or scattering when traversing a layer of material Z can be expressed quantitatively in terms of a linear attenuation coefficient mu (cm(-1)). Since mu is dependent on the material's density, rho (g cm(-3)), wh...

journal_title：Physics in medicine and biology

authors： Hubbell JH

更新日期：1999-01-01 00:00:00

abstract：:Task group 43 (TG43)-based dosimetry algorithms are efficient for brachytherapy dose calculation in water. However, human tissues have chemical compositions and densities different than water. Moreover, the mutual shielding effect of seeds on each other (interseed attenuation) is neglected in the TG43-based dosimetry ...

journal_title：Physics in medicine and biology

authors： Afsharpour H,Landry G,D'Amours M,Enger S,Reniers B,Poon E,Carrier JF,Verhaegen F,Beaulieu L

更新日期：2012-06-07 00:00:00

abstract：:In this paper the propagation of a UWB pulse into a layered model of the human body is studied to characterize absorption and reflection of the UWB signal due to the different body tissues. Several time behaviours for the incident UWB pulse are considered and compared with reference to the feasibility of breath and he...

journal_title：Physics in medicine and biology

authors： Cavagnaro M,Pittella E,Pisa S

更新日期：2013-12-21 00:00:00

abstract：:Conversion factors, which relate the kerma-area product to effective dose, have been estimated for paediatric cardiac x-ray angiography. Monte Carlo techniques have been used to calculate the conversion factors for a wide range of projection angles for children of five ages and for adults. Correction factors are provi...

journal_title：Physics in medicine and biology

authors： Schmidt PW,Dance DR,Skinner CL,Smith IA,McNeill JG

更新日期：2000-10-01 00:00:00

abstract：:Breast MRI is frequently performed prior to breast conserving surgery in order to assess the location and extent of the lesion. Ideally, the surgeon should also be able to use the image information during surgery to guide the excision and this requires that the MR image is co-registered to conform to the patient's pos...

journal_title：Physics in medicine and biology

authors： Ebrahimi M,Siegler P,Modhafar A,Holloway CM,Plewes DB,Martel AL

更新日期：2014-04-07 00:00:00

abstract：:The reproducibility of polyacrylamide gel (PAG) dosimetry has been evaluated when used to verify two radiotherapy treatment plans of increasing complexity. The plans investigated were a three-field coplanar arrangement, using the linac jaws for field shaping, and a four-field, conformal, non-coplanar plan using precis...

journal_title：Physics in medicine and biology

authors： Cosgrove VP,Murphy PS,McJury M,Adams EJ,Warrington AP,Leach MO,Webb S

更新日期：2000-05-01 00:00:00

abstract：:Dose calculations of pencil beam scanning treatment plans rely on the accuracy of proton spot profiles; not only the primary component but also the broad tail components. Four films are placed at several locations in air and multiple depths in Solidwater® for six selected energies. The films used for the primary compo...

journal_title：Physics in medicine and biology

authors： Lin L,Ainsley CG,McDonough JE

更新日期：2013-09-07 00:00:00

abstract：:A leaf-setting algorithm is developed for generating arbitrary beam intensity profiles in discrete levels using dynamic multileaf collimators (DMLCs). The algorithm starts with the algebraic expression for the area under the beam profile. It is shown that the coefficients in this expression can be transformed into the...

journal_title：Physics in medicine and biology

authors： Ma L,Boyer AL,Xing L,Ma CM

更新日期：1998-06-01 00:00:00

abstract：:Energy and angular distributions of electron beams with different energies were simulated by Monte Carlo calculations. These beams were generated by the NOVAC7 system (Hitesys, Italy), a mobile electron accelerator specifically dedicated to intra-operative radiation therapy (IORT). The electron beam simulations were v...

journal_title：Physics in medicine and biology

authors： Pimpinella M,Mihailescu D,Guerra AS,Laitano RF

更新日期：2007-10-21 00:00:00

abstract：:This paper describes the development and characterization of a fully automated in vitro cell irradiator using an electronic brachytherapy source to perform radiation sensitivity bioassays. This novel irradiator allows complex variable dose and dose rate schemes to be delivered to multiple wells of 96-well culture plat...

journal_title：Physics in medicine and biology

authors： Fowler TL,Fulkerson RK,Micka JA,Kimple RJ,Bednarz BP

更新日期：2014-03-21 00:00:00

abstract：:Finite element (FE) modeling provides a useful tool to understand the mechanical behavior of complex tissues, such as cancers, in a variety of testing conditions. Although a number of numerical and analytical models for cancerous tumors are retrievable in the literature, none of these models is capable of completely d...

journal_title：Physics in medicine and biology

authors： Islam MT,Reddy JN,Righetti R

更新日期：2018-10-24 00:00:00