Abstract:
:Task group 43 (TG43)-based dosimetry algorithms are efficient for brachytherapy dose calculation in water. However, human tissues have chemical compositions and densities different than water. Moreover, the mutual shielding effect of seeds on each other (interseed attenuation) is neglected in the TG43-based dosimetry platforms. The scientific community has expressed the need for an accurate dosimetry platform in brachytherapy. The purpose of this paper is to present ALGEBRA, a Monte Carlo platform for dosimetry in brachytherapy which is sufficiently fast and accurate for clinical and research purposes. ALGEBRA is based on the GEANT4 Monte Carlo code and is capable of handling the DICOM RT standard to recreate a virtual model of the treated site. Here, the performance of ALGEBRA is presented for the special case of LDR brachytherapy in permanent prostate and breast seed implants. However, the algorithm is also capable of handling other treatments such as HDR brachytherapy.
journal_name
Phys Med Bioljournal_title
Physics in medicine and biologyauthors
Afsharpour H,Landry G,D'Amours M,Enger S,Reniers B,Poon E,Carrier JF,Verhaegen F,Beaulieu Ldoi
10.1088/0031-9155/57/11/3273subject
Has Abstractpub_date
2012-06-07 00:00:00pages
3273-80issue
11eissn
0031-9155issn
1361-6560journal_volume
57pub_type
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