Abstract:
:Conversion factors, which relate the kerma-area product to effective dose, have been estimated for paediatric cardiac x-ray angiography. Monte Carlo techniques have been used to calculate the conversion factors for a wide range of projection angles for children of five ages and for adults. Correction factors are provided so that the conversion factors can be adjusted for different tube potentials and filtrations.
journal_name
Phys Med Bioljournal_title
Physics in medicine and biologyauthors
Schmidt PW,Dance DR,Skinner CL,Smith IA,McNeill JGdoi
10.1088/0031-9155/45/10/323subject
Has Abstractpub_date
2000-10-01 00:00:00pages
3095-107issue
10eissn
0031-9155issn
1361-6560journal_volume
45pub_type
杂志文章abstract::We have developed and tested an MR-compatible gamma probe to simultaneously obtain anatomical information and functional information during surgery. The probe consists of a probe head, an optical fibre bundle and a photo-multiplier tube (PMT). The NaI(T1) scintillator contained in the probe head is connected to a 7 m ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/49/15/005
更新日期:2004-08-07 00:00:00
abstract::This work presents a Monte Carlo model of Leksell Gamma Knife Perfexion as well as the main parameters of the dose distribution in the standard phantom obtained using this model. The model is developed in the Geant4 simulation toolkit in a modular way which enables its reuse in other Perfexion studies. Large phase spa...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/59/24/7609
更新日期:2014-12-21 00:00:00
abstract::Radiotherapy treatment planning is associated with uncertainties. Examples are uncertainties in the tumour location due to organ movement or the inter/intra observer variability in target definition. Different approaches to incorporate uncertainties into IMRT optimization have been proposed. In this note, we point out...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/51/23/N04
更新日期:2006-12-07 00:00:00
abstract::Task group 43 (TG43)-based dosimetry algorithms are efficient for brachytherapy dose calculation in water. However, human tissues have chemical compositions and densities different than water. Moreover, the mutual shielding effect of seeds on each other (interseed attenuation) is neglected in the TG43-based dosimetry ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/57/11/3273
更新日期:2012-06-07 00:00:00
abstract::The purpose of this work was to study and quantify the differences in dose distributions computed with some of the newest dose calculation algorithms available in commercial planning systems. The study was done for clinical cases originally calculated with pencil beam convolution (PBC) where large density inhomogeneit...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/52/13/002
更新日期:2007-07-07 00:00:00
abstract::Component-based normalization is a method used to compensate for the sensitivity of each of the lines of response acquired in positron emission tomography. This method consists of modelling the sensitivity of each line of response as a product of multiple factors, which can be classified as time-invariant, time-varian...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/61/9/3554
更新日期:2016-05-07 00:00:00
abstract::The peak CT number (CT) and full width at half maximum (FWHM) were obtained from the image profiles of aluminium of thickness ranging from 0.1-9.5 mm. The scans were performed at different fields of view (FOVs) and with different reconstruction algorithms ('bone' and 'standard'). Above 3 mm, CT and FWHM provide measur...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/43/3/013
更新日期:1998-03-01 00:00:00
abstract::Although interventional x-ray angiography (XA) procedures involve relatively high radiation doses that can lead to deterministic tissue reactions in addition to stochastic effects, convenient and accurate estimation of absorbed organ doses has traditionally been out of reach. This has mainly been due to the absence of...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/61/8/3063
更新日期:2016-04-21 00:00:00
abstract::Hair loss is a feared side effect of chemotherapy treatment. It may be prevented by cooling the scalp during administration of cytostatics. The supposed mechanism is that by cooling the scalp, both temperature and perfusion are diminished, affecting drug supply and drug uptake in the hair follicle. However, the effect...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/50/17/010
更新日期:2005-09-07 00:00:00
abstract::Many of the inadequacies of the system presently used for surveying environments containing penetrating radiation stem from the impossibility of defining a radiation parameter which is additive, measurable and closely related to peak dose equivalent in the body. Many of the present conceptual difficulties would be eli...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/20/6/012
更新日期:1975-11-01 00:00:00
abstract::Proton therapy potentially offers excellent dose conformality and reduction in integral dose. The superior dose distribution is, however, much more sensitive to the radiological depth along the beam path than for photon fields. Variations in this depth due to inaccurate planning calculation, setup uncertainty, respira...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/53/5/016
更新日期:2008-03-07 00:00:00
abstract::Range verification in proton therapy is a critical quality assurance task. We studied the feasibility of online range verification based on proton-induced acoustic signals, using a bidirectional long-short-term-memory recurrent neural network and various signal processing techniques. Dose distribution of 1D pencil pro...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/1361-6560/abaa5e
更新日期:2020-11-05 00:00:00
abstract::This work applies a previously developed analytical algorithm to the reconstruction problem in a rotating multi-segment slant-hole (RMSSH) SPECT system. The RMSSH collimator has greater detection efficiency than the parallel-hole collimator with comparable spatial resolution at the expense of limited common volume-of-...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/54/13/024
更新日期:2009-07-07 00:00:00
abstract::An optimized configuration of multi-pinhole aperture can improve the spatial resolution and the sensitivity of pinhole SPECT simultaneously. In this study, an optimization strategy of the multi-pinhole configuration with a small detector is proposed for mouse cardiac imaging. A 14 mm-diameter spherical field-of-view (...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/60/2/473
更新日期:2015-01-21 00:00:00
abstract::K line x-ray fluorescence (KXRF) measurements of bone lead have emerged as a promising new biological marker of internal lead dose in epidemiological studies. Some disagreements exist, however, over the analysis of data at low levels of bone lead concentration. In this study, we performed 30 serial measurements on eac...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/40/9/007
更新日期:1995-09-01 00:00:00
abstract::A parametric model for the x-ray linear attenuation coefficient is used to describe the compositional dependence of Hounsfield numbers measured by medical CT scanners. Measurements with materials of known density and composition, that span and evenly sample the compositional range of tissues, are written as linear sim...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/59/23/7479
更新日期:2014-12-07 00:00:00
abstract::Statistically based iterative image reconstruction methods have been developed for emission tomography. One important component in iterative image reconstruction is the system matrix, which defines the mapping from the image space to the data space. Several groups have demonstrated that an accurate system matrix can i...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/50/14/007
更新日期:2005-07-21 00:00:00
abstract::A method to measure the detector-to-object distance from the images obtained with stationary high-spatial-resolution gamma-ray cameras for in vivo studies has been developed. It exploits the shift of the imaged object in the image plane, obtained at a certain tilt of the parallel-hole collimator. A linear dependence o...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/51/9/N04
更新日期:2006-05-07 00:00:00
abstract::The purpose of this investigation is to propose new compensator design strategies for protons and heavier particles which are based on pencil-beam (PB) dose calculations and which significantly reduce the dose to tissues downstream from the target, yet provide acceptable target coverage under conditions of patient mot...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/42/7/005
更新日期:1997-07-01 00:00:00
abstract::Over the course of radiation therapy, a patient's anatomy may change substantially. The relatively recent addition of frequent in-room imaging to assist with patient localization has provided a database of images that may be used to recalculate dose distributions for adaptive radiotherapy purposes. The TomoTherapy Hi-...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/56/24/010
更新日期:2011-12-21 00:00:00
abstract::The interaction of biomedical ultrasound with spherical tumours in the human body is investigated using analytic methods which predict the angular distribution of the ultrasound scattered by the tumour. Both the tumour and the surrounding tissue are considered to be lossy elastic media, which support shear-wave modes ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/37/11/001
更新日期:1992-11-01 00:00:00
abstract::Both inhomogeneity in the main magnetic field and non-linearity in the gradient fields introduce errors in NMR images reconstructed from projections. It is found that the image artefacts caused by these two sources are separable. The inhomogeneous main field blurs the image while the nonlinear gradients distort the im...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/28/8/005
更新日期:1983-08-01 00:00:00
abstract::Grating-based x-ray phase-contrast imaging provides three simultaneous image channels originating from a single image acquisition. While the phase signal provides direct access to the electron density in tomography, there is additional information on sub-resolutional structural information which is called dark-field s...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/1361-6560/ab9704
更新日期:2020-09-18 00:00:00
abstract::Our aim is to investigate the impact of respiratory motion on tumor quantification and delineation in static PET/CT imaging using a population of patient respiratory traces. A total of 1295 respiratory traces acquired during whole body PET/CT imaging were classified into three types according to the qualitative shape ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/54/24/007
更新日期:2009-12-21 00:00:00
abstract::The trend towards conformal, intensity modulated radiotherapy treatments has established the need for a true integrating dosimeter. In traditional radiotherapy, radiographic film dosimetry is commonly used. The accuracy and reproducibility of film optical density as an indicator of dose is influenced by several variab...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/46/5/305
更新日期:2001-05-01 00:00:00
abstract::The measured attenuation correction technique is widely used in cardiac positron tomographic studies. However, the success of this technique is limited because of insufficient counting statistics achievable in practical transmission scan times, and of the scattered radiation in transmission measurement which leads to ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/41/10/024
更新日期:1996-10-01 00:00:00
abstract::The purpose of this paper for four-dimensional (4D) computed tomography (CT) is threefold. (1) A new spatiotemporal model is presented from the matrix perspective with the row dimension in space and the column dimension in time, namely the robust PCA (principal component analysis)-based 4D CT model. That is, instead o...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/56/11/002
更新日期:2011-06-07 00:00:00
abstract::Shear wave elastography (SWE) is a potential tool to non-invasively assess cardiac muscle stiffness. This study focused on the effect of the orthotropic material properties and mechanical loading on the performance of cardiac SWE, as it is known that these factors contribute to complex 3D anisotropic shear wave propag...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/1361-6560/aaaffe
更新日期:2018-03-23 00:00:00
abstract::We report a simulation study on diffuse reflective optical computed tomography, in which continuous-wave sources and detectors are placed on the plane surface of a semi-infinite body. We adopted a simple Tikhonov regularization in the inverse problem and demonstrated the feasibility of three-dimensional reconstruction...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/49/10/004
更新日期:2004-05-21 00:00:00
abstract::Electron depth-dose curves and spectra have been measured from an experimental accelerator on which both energy and spectral shape could be varied independently. The measurements were made at nominal energies of 6 and 12 MeV, with the energy spread (FWHM) varied from 1.7% to over 10% of average energy. Changes in dept...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/28/12/005
更新日期:1983-12-01 00:00:00