Simulation study to improve the performance of a whole-body PbF2 Cherenkov TOF-PET scanner.

abstract：:The architecture of multi-layer imagers (MLIs) can be exploited to provide megavoltage spectral imaging (MVSPI) for specific imaging tasks. In the current work, we investigated bone suppression and gold fiducial contrast enhancement as two clinical tasks which could be improved with spectral imaging. A method based on...

journal_title：Physics in medicine and biology

authors： Myronakis M,Hu YH,Fueglistaller R,Wang A,Baturin P,Huber P,Morf D,Star-Lack J,Berbeco R

更新日期：2018-05-10 00:00:00

abstract：:A Geiger-mode avalanche photodiode (Si-PM) is a promising photodetector for PET, especially for use in a magnetic resonance imaging (MRI) system, because it has high gain and is less sensitive to a static magnetic field. We developed a Si-PM-based depth-of-interaction (DOI) PET system for small animals. Hamamatsu 4 × ...

journal_title：Physics in medicine and biology

authors： Yamamoto S,Imaizumi M,Watabe T,Watabe H,Kanai Y,Shimosegawa E,Hatazawa J

更新日期：2010-10-07 00:00:00

abstract：:In recent codes of practice for reference dosimetry in clinical proton beams using ionization chambers, it is recommended to perform the measurement in a water phantom. However, in situations where the positioning accuracy is very critical, it could be more convenient to perform the measurement in a plastic phantom. I...

journal_title：Physics in medicine and biology

authors： Palmans H,Symons JE,Denis JM,de Kock EA,Jones DT,Vynckier S

更新日期：2002-09-07 00:00:00

abstract：:The x-ray exposure to patients has become a major concern in computed tomography (CT) and minimizing the radiation exposure has been one of the major efforts in the CT field. Due to plenty high-attenuation tissues in the human chest, under low-dose scan protocols, thoracic low-dose CT (LDCT) images tend to be severely...

journal_title：Physics in medicine and biology

authors： Chen Y,Yang Z,Hu Y,Yang G,Zhu Y,Li Y,Luo L,Chen W,Toumoulin C

更新日期：2012-05-07 00:00:00

abstract：:The temperature sensitivities of absorption and reduced scattering coefficients in the range 700-1000 nm are determined for the liquid phantom Intralipid using spatially resolved continuous wave measurements. The measurements were conducted on a 10 L heated volume of 1% Intralipid subjected to a 40-30 degrees C coolin...

journal_title：Physics in medicine and biology

authors： McGlone VA,Martinsen P,Künnemeyer R,Jordan B,Cletus B

更新日期：2007-05-07 00:00:00

abstract：:Recent research has suggested that endothelialization of vascular stents is crucial to reducing the risk of late stent thrombosis. With a resolution of approximately 10 microm, optical coherence tomography (OCT) may be an appropriate imaging modality for visualizing the vascular response to a stent and measuring the p...

journal_title：Physics in medicine and biology

authors： Bonnema GT,Cardinal KO,Williams SK,Barton JK

更新日期：2008-06-21 00:00:00

abstract：:Many applications in medical imaging include image registration for matching of images from the same or different modalities. In the case of full data sampling, the respective reconstructed images are usually of such a good image quality that standard deformable volume-to-volume (3D-3D) registration approaches can be ...

journal_title：Physics in medicine and biology

authors： Flach B,Brehm M,Sawall S,Kachelrieß M

更新日期：2014-12-21 00:00:00

abstract：:Recent studies have demonstrated the feasibility of transcranial high-intensity focused ultrasound (HIFU) therapy in the brain using adaptive focusing techniques. However, the complexity of the procedures imposes provision of accurate targeting, monitoring and control of this emerging therapeutic modality in order to ...

journal_title：Physics in medicine and biology

authors： Larrat B,Pernot M,Aubry JF,Dervishi E,Sinkus R,Seilhean D,Marie Y,Boch AL,Fink M,Tanter M

更新日期：2010-01-21 00:00:00

abstract：:In interstitial heating one of the main requirements for achieving a certain elevated temperature in a tumour is that the effective power per applicator (Peff), i.e. the power which is actually deposited in the tissue, is sufficiently high. In this paper this requirement is discussed for the applicators of the 27 MHz ...

journal_title：Physics in medicine and biology

authors： Kaatee RS,Crezee J,Kanis AP,Lagendijk JJ,Levendag PC,Visser AG

更新日期：1997-06-01 00:00:00

abstract：:A method for extracting the dark-field signal in propagation-based phase-contrast imaging is proposed. In the case of objects consisting predominantly of a single material, or several different materials with similar ratios of the real decrement to the imaginary part of the complex refractive index, the proposed metho...

journal_title：Physics in medicine and biology

authors： Gureyev TE,Paganin DM,Arhatari B,Taba ST,Lewis S,Brennan PC,Quiney HM

更新日期：2020-11-17 00:00:00

abstract：:A new hybrid imaging-treatment modality, the MRI-Linac, involves the irradiation of the patient in the presence of a strong magnetic field. This field acts on the charged particles, responsible for depositing dose, through the Lorentz force. These conditions require a dose calculation engine capable of taking into con...

journal_title：Physics in medicine and biology

authors： Hissoiny S,Raaijmakers AJ,Ozell B,Després P,Raaymakers BW

更新日期：2011-08-21 00:00:00

abstract：:We have developed deformable and durable optical tissue phantoms with a simple and well-defined microstructure including a novel combination of scatterers and a matrix material. These were developed for speckle and elastography investigations in optical coherence tomography, but should prove useful in many other field...

journal_title：Physics in medicine and biology

authors： Bisaillon CE,Lamouche G,Maciejko R,Dufour M,Monchalin JP

更新日期：2008-07-07 00:00:00

abstract：:In this work we present the first delivery of intensity modulated arc therapy on the Elekta Unity 1.5 T MR-linac. The machine's current IMRT based control system was modified suitably to enable dynamic delivery of radiation, for the purpose of exploring MRI-guided radiation therapy adaptation modes in a research setti...

journal_title：Physics in medicine and biology

authors： Kontaxis C,Woodhead PL,Bol GH,Lagendijk JJW,Raaymakers BW

更新日期：2020-12-23 00:00:00

abstract：:This study was carried out to investigate whether the electronic portal imaging (EPI) acquisition process could be optimized, and as a result tolerance and action levels be set for the PIPSPro QC-3V phantom image quality assessment. The aim of the optimization process was to reduce the dose delivered to the patient wh...

journal_title：Physics in medicine and biology

authors： McGarry CK,Grattan MW,Cosgrove VP

更新日期：2007-12-07 00:00:00

abstract：:The purpose of this work is to model electron contamination in clinical photon beams and to commission the source model using measured data for Monte Carlo treatment planning. In this work, a planar source is used to represent the contaminant electrons at a plane above the upper jaws. The source size depends on the di...

journal_title：Physics in medicine and biology

authors： Yang J,Li JS,Qin L,Xiong W,Ma CM

更新日期：2004-06-21 00:00:00

abstract：:In order to analyse the respective roles of ion concentration and fractional volume of the interstitial compartment as determinants of the impedance, Z, of renal medullary tissue, a model was needed in which both these factors could be varied independently. An array of blood cell suspensions ions in saline (different ...

journal_title：Physics in medicine and biology

authors： Niewiadomski W,Sadowski J,Badzyńska B,Rasmussen SN

更新日期：1990-11-01 00:00:00

abstract：:109Cd K x-ray fluorescence (XRF) measurement systems from two research centres were used to measure tibia lead content in a population (n = 530) of young adults. The group mean bone lead contents (+/-SEM) determined by McMaster University (n = 214) and the University of Maryland (n = 316) were 2.80 +/- 0.51 and 2.33 +...

journal_title：Physics in medicine and biology

authors： McNeill FE,Stokes L,Chettle DR,Kaye WE

更新日期：1999-09-01 00:00:00

abstract：:A new component module (CM), designated DYNVMLC, was developed to fully model the geometry of the Varian Millennium 120 leaf collimator using the BEAMnrc Monte Carlo code. The model includes details such as the leaf driving screw hole, support railing groove and leaf tips. Further modifications also allow sampling of ...

journal_title：Physics in medicine and biology

authors： Heath E,Seuntjens J

更新日期：2003-12-21 00:00:00

abstract：:A bilateral comparison of national dosimetric standards for high dose rate brachytherapy has been conducted between the Laboratoire National Henri Becquerel and the University of Wisconsin Accredited Dosimetry Calibration Laboratory. A complete overview of the methods that are currently in use to establish the two nat...

journal_title：Physics in medicine and biology

authors： Douysset G,Gouriou J,Delaunay F,DeWerd L,Stump K,Micka J,Laboratoire National Henri Becquerel.,University of Wisconsin Accredited Dosimetry Calibration Laboratory.

更新日期：2005-05-07 00:00:00

abstract：:Finite element (FE) modeling provides a useful tool to understand the mechanical behavior of complex tissues, such as cancers, in a variety of testing conditions. Although a number of numerical and analytical models for cancerous tumors are retrievable in the literature, none of these models is capable of completely d...

journal_title：Physics in medicine and biology

authors： Islam MT,Reddy JN,Righetti R

更新日期：2018-10-24 00:00:00

abstract：:Accurate scatter correction is required to produce high-quality reconstructions of x-ray cone-beam computed tomography (CBCT) scans. This paper describes new scatter kernel superposition (SKS) algorithms for deconvolving scatter from projection data. The algorithms are designed to improve upon the conventional approac...

journal_title：Physics in medicine and biology

authors： Sun M,Star-Lack JM

更新日期：2010-11-21 00:00:00

abstract：:Magnetic Resonance Electrical Impedance Tomography (MREIT) is an MRI method that enables mapping of internal conductivity and/or current density via measurements of magnetic flux density signals. The MREIT measures only the z-component of the induced magnetic flux density B = (Bx, By, Bz) by external current injection...

journal_title：Physics in medicine and biology

authors： Jeong WC,Chauhan M,Sajib SZ,Kim HJ,Serša I,Kwon OI,Woo EJ

更新日期：2014-09-07 00:00:00

abstract：:A hybrid proportional-integral-in-time and cost-minimizing-in-space feedback control system for electromagnetic, deep regional hyperthermia is proposed. The unique features of this controller are that (1) it uses temperature, not specific absorption rate, as the criterion for selecting the relative phases and amplitud...

journal_title：Physics in medicine and biology

authors： Kowalski ME,Jin JM

更新日期：2003-03-07 00:00:00

abstract：:The aim of the present work was to implement the kinetics of cisplatin into a previously developed tumour growth model and to simulate the combined cisplatin-radiotherapy treatment with the emphasis on time sequencing and scheduling of drug and radiation. An investigation into whether the effect of cisplatin-radiation...

journal_title：Physics in medicine and biology

authors： Marcu L,Bezak E,Olver I

更新日期：2006-08-07 00:00:00

abstract：:The values of the replacement correction factors (P(repl), or in the IAEA's notation p(dis)p(cav)) used for cylindrical chambers in high-energy photon beams represent one of the most significant differences between the AAPM and the IAEA dosimetry protocols. In a previous study (Wang L L W and Rogers D W O 2008 Med. Ph...

journal_title：Physics in medicine and biology

authors： Wang LL,Rogers DW

更新日期：2009-03-21 00:00:00

abstract：:In order (i) to evaluate the dose uncertainty of the mouthpiece in daily use during intensity-modulated radiotherapy of patients with head and neck cancer, and (ii) to present a system for in vivo dosimetry of the oral mucosa, we equipped the mouthpiece with alanine dosimeter probes for in vivo dosimetry. The aim was ...

journal_title：Physics in medicine and biology

authors： Wagner D,Anton M,Vorwerk H

更新日期：2011-03-07 00:00:00

abstract：:For treatments with dynamic intensity modulated radiotherapy (IMRT), the adjustment of multileaf collimator (MLC) parameters affecting both the optimization algorithm and dose distributions is crucial. The main parameters characterizing the MLC are the transmission (T) and the dosimetric leaf separation (DLS). The aim...

journal_title：Physics in medicine and biology

authors： Chauvet I,Petitfils A,Lehobey C,Kristner JY,Brunet Y,Lembrez R,Gaboriaud G,Mazal A,Zefkili S,Rosenwald JC

更新日期：2005-02-21 00:00:00

abstract：:The formulation of intensity modulated radiation therapy (IMRT) planning aspects frequently uses the dose-volume histogram (DVH), whereas plan computations often happen in the more desirable convex IMRT optimization framework. Inspired by a recent publication of Zinchenko et al (2008 Phys. Med. Biol. 53 3231-50), this...

journal_title：Physics in medicine and biology

authors： Kratt K,Scherrer A

更新日期：2009-06-21 00:00:00

abstract：:We propose and evaluate the performance of an improved preclinical positron emission tomography (PET) scanner design, referred to as Polaroid-PET, consisting of a detector equipped with a layer of horizontal Polaroid to filter scintillation photons with vertical polarization. This makes it possible to improve the spat...

journal_title：Physics in medicine and biology

authors： Sanaat A,Ashrafi-Belgabad A,Zaidi H

更新日期：2020-12-02 00:00:00

abstract：:Magnetic resonance-guided radiation therapy (MR-GRT) offers great potential to improve radiation treatment outcomes by providing more accurate and patient-tailored therapy. Despite superior soft tissue contrast in MRI, one of the challenges towards MRI-only workflows is that the process often requires some sort of 'MR...

journal_title：Physics in medicine and biology

authors： Nosrati R,Paudel M,Ravi A,Pejovic-Milic A,Morton G,Stanisz GJ

更新日期：2019-07-16 00:00:00