Correlation between human and model observer performance for discrimination task in CT.

abstract：:To investigate the profile measurement capabilities of an IBA-Dosimetry scintillation detector and to assess its feasibility for determining the low-intensity tails of pencil-beam scanning spots, the responses of the scintillation detector and Gafchromic EBT2 film to a 115 MeV proton spot were measured in-air at the i...

journal_title：Physics in medicine and biology

authors： Lin L,Ainsley CG,Mertens T,De Wilde O,Talla PT,McDonough JE

更新日期：2013-06-21 00:00:00

abstract：:Using Monte Carlo simulation of 99Tcm single-photon-emission computed tomography (SPECT), we investigate the effects of tissue-background activity, tumour location, patient size, uncertainty of energy windows, and definition of tumour region on the accuracy of quantification. The dual-energy-window method of correctio...

journal_title：Physics in medicine and biology

authors： Luo JQ,Koral KF,Ljungberg M,Floyd CE Jr,Jaszczak RJ

更新日期：1995-01-01 00:00:00

abstract：:Persistence of the video signal between TV frames, an effect also known as image lag, can lead to anomalously good contrast-detail test results for fluoroscopy systems. In this practical paper, a simple method is described which quantifies lag in fluoroscopy systems and corrects for its effect on threshold contrast. A...

journal_title：Physics in medicine and biology

authors： Marshall NW,Kotre CJ

更新日期：2002-03-21 00:00:00

abstract：:Mitral and aortic valve replacement is a procedure which is common in cardiac surgery. Some of these replacement valves are mechanical and contain moving metal parts. Should the patient in whom such a valve has been implanted be involved in magnetic resonance imaging, there is a possible dangerous interaction between ...

journal_title：Physics in medicine and biology

authors： Robertson NM,Diaz-Gomez M,Condon B

更新日期：2000-12-01 00:00:00

abstract：:Radiation therapy is an image-guided process whose success critically depends on the imaging modality used for treatment planning and the level of integration of the available imaging information. In this work, we establish a dose optimization framework for incorporating metabolic information from functional imaging m...

journal_title：Physics in medicine and biology

authors： Xing L,Cotrutz C,Hunjan S,Boyer AL,Adalsteinsson E,Spielman D

更新日期：2002-10-21 00:00:00

abstract：:We discuss the use of terahertz time domain spectroscopy for studies of conformational flexibility and conformational change in biomolecules. Protein structural dynamics are vital to biological function with protein flexibility affecting enzymatic reaction rates and sensory transduction cycling times. Conformational m...

journal_title：Physics in medicine and biology

authors： Markelz A,Whitmire S,Hillebrecht J,Birge R

更新日期：2002-11-07 00:00:00

abstract：:There are three ways to determine the spectrum of a clinical photon beam: direct measurement, modelling the source and reconstruction from ion-chamber measurements. We focus on reconstruction because the necessary equipment is readily available and it provides independent confirmation of source models for a given mach...

journal_title：Physics in medicine and biology

authors： Armbruster B,Hamilton RJ,Kuehl AK

更新日期：2004-11-21 00:00:00

abstract：:Diffuse optical imaging using non-ionizing radiation is a non-invasive method that shows promise towards breast cancer diagnosis. Hand-held optical imagers show potential for clinical translation of the technology, yet they have not been used towards 3D tomography. Herein, 3D tomography of human breast tissue in vivo ...

journal_title：Physics in medicine and biology

authors： Erickson SJ,Martinez SL,DeCerce J,Romero A,Caldera L,Godavarty A

更新日期：2013-03-07 00:00:00

abstract：:Dynamic positron emission tomography (PET) imaging can provide information about metabolic changes over time, used for kinetic analysis and auxiliary diagnosis. Existing deep learning-based reconstruction methods have too many trainable parameters and poor generalization, and require mass data to train the neural netw...

journal_title：Physics in medicine and biology

authors： Wang B,Liu H

更新日期：2020-10-13 00:00:00

abstract：:Managing uncertainty is a major challenge in radiation therapy treatment planning, including uncertainty induced by intrafraction motion, which is particularly important for tumours in the thorax and abdomen. Common methods to account for motion are to introduce a margin or to convolve the static dose distribution wit...

journal_title：Physics in medicine and biology

authors： Chan TC,Bortfeld T,Tsitsiklis JN

更新日期：2006-05-21 00:00:00

abstract：:Microbeam radiation therapy (MRT) is a treatment approach in radiation therapy where the treatment field is spatially fractionated into arrays of a few tens of micrometre wide planar beams of unusually high peak doses separated by low dose regions of several hundred micrometre width. In preclinical studies, this treat...

journal_title：Physics in medicine and biology

authors： Debus C,Oelfke U,Bartzsch S

更新日期：2017-10-19 00:00:00

abstract：:The aim of this study is to investigate the use of mathematical morphology for the determination of left ventricular contours in scintigraphic images using multigated radionuclide angiography. We have developed a completely automatic method that first restores the image with a Wiener filter, then finds the region wher...

journal_title：Physics in medicine and biology

authors： Pladellorens J,Serrat J,Castell A,Yzuel MJ

更新日期：1993-12-01 00:00:00

abstract：:Experimental radiobiological investigations of fast neutron beams involve irradiation of thin cell layers. The irradiation of cells is done either in free air or with a material such as graphite, TE plastic or bone-equivalent plastic covering the cells. This paper discusses the computed dose distributions in LET at sh...

journal_title：Physics in medicine and biology

authors： Bhatia DP,Nagarajan PS

更新日期：1979-09-01 00:00:00

abstract：:Radiochromic films are useful as dosimeters in high-precision radiotherapy owing to their high spatial resolution. However, when a particle beam is measured using a radiochromic film, the dose cannot be estimated accurately because the film darkness varies with variations in linear energy transfer (LET). This paper pr...

journal_title：Physics in medicine and biology

authors： Kawashima M,Matsumura A,Souda H,Tashiro M

更新日期：2020-06-15 00:00:00

abstract：:This paper introduces a novel compartmental model describing the excretion of 18F-fluoro-deoxyglucose (FDG) in the renal system and a numerical method based on the maximum likelihood for its reduction. This approach accounts for variations in FDG concentration due to water re-absorption in renal tubules and the increa...

journal_title：Physics in medicine and biology

authors： Garbarino S,Caviglia G,Sambuceti G,Benvenuto F,Piana M

更新日期：2014-05-21 00:00:00

abstract：:An alternative to gamma (gamma) histograms for ROI-based quantitative comparisons of dose distributions using the gamma concept is proposed. The method provides minimum values of dose difference and distance-to-agreement such that a pre-set fraction of the region of interest passes the gamma test. Compared to standard...

journal_title：Physics in medicine and biology

authors： Dvorak P

更新日期：2009-06-21 00:00:00

abstract：:The aim of the study is to determine PTV margin for inter-observer variability in the volumetric modulated arc therapy (VMAT) prostate radiotherapy with high-dose volumetric CT (HDVCT) and conventional helical CT (CCT) for planning. Secondly to investigate the impact of geometric (PTV expansion) and dosimetric (confor...

journal_title：Physics in medicine and biology

authors： Cho YB,Alasti H,Kong V,Catton C,Berlin A,Chung P,Bayley A,Jaffray D

更新日期：2019-03-14 00:00:00

abstract：:Protons and carbon ion beams for hadron therapy can be delivered by cyclotrons with a fixed energy. In order to treat patients, an energy degrader along the beam line will be used to match the particle range with the target depth. Fragmentation reactions of carbon ions inside the degrader material could introduce a sm...

journal_title：Physics in medicine and biology

authors： Morone MC,Calabretta L,Cuttone G,Fiorini F

更新日期：2008-11-07 00:00:00

abstract：:Magnetic Resonance Electrical Impedance Tomography (MREIT) is an MRI method that enables mapping of internal conductivity and/or current density via measurements of magnetic flux density signals. The MREIT measures only the z-component of the induced magnetic flux density B = (Bx, By, Bz) by external current injection...

journal_title：Physics in medicine and biology

authors： Jeong WC,Chauhan M,Sajib SZ,Kim HJ,Serša I,Kwon OI,Woo EJ

更新日期：2014-09-07 00:00:00

abstract：:The MRI accelerator, a combination of a 6 MV linear accelerator with a 1.5 T MRI, facilitates continuous patient anatomy updates regarding translations, rotations and deformations of targets and organs at risk. Accounting for these demands high speed, online intensity-modulated radiotherapy (IMRT) re-optimization. In ...

journal_title：Physics in medicine and biology

authors： Bol GH,Hissoiny S,Lagendijk JJ,Raaymakers BW

更新日期：2012-03-07 00:00:00

abstract：:Target motion is one of the major limitations of each high precision radiation therapy. Using advanced active beam delivery techniques, such as the magnetic raster scanning system for particle irradiation, the interplay between time-dependent beam and target position heavily distorts the applied dose distribution. Thi...

journal_title：Physics in medicine and biology

authors： Li Q,Groezinger SO,Haberer T,Rietzel E,Kraft G

更新日期：2004-07-21 00:00:00

abstract：:The (83)Kr magnetic resonance (MR) relaxation time T(1) of krypton gas in contact with model surfaces was previously found to be highly sensitive to surface composition, surface-to-volume ratio, and surface temperature. The work presented here explored aspects of pulmonary (83)Kr T(1) relaxation measurements in excise...

journal_title：Physics in medicine and biology

authors： Stupic KF,Elkins ND,Pavlovskaya GE,Repine JE,Meersmann T

更新日期：2011-07-07 00:00:00

abstract：:Micro-CT is widely used in preclinical studies, generating substantial interest in extending its capabilities in functional imaging applications such as blood perfusion and cardiac function. However, imaging cardiac structure and function in mice is challenging due to their small size and rapid heart rate. To overcome...

journal_title：Physics in medicine and biology

authors： Holbrook M,Clark DP,Badea CT

更新日期：2018-01-09 00:00:00

abstract：:Diffusion tensor - magnetic resonance electrical impedance tomography (DT-MREIT) is an imaging modality to obtain low-frequency anisotropic conductivity distribution employing diffusion tensor imaging (DTI) and magnetic resonance electrical impedance tomography (MREIT) techniques. DT-MREIT is based on the linear relat...

journal_title：Physics in medicine and biology

authors： Sadighi M,Sisman M,Acikgoz BC,Eroglu HH,Eyuboglu BM

更新日期：2021-01-20 00:00:00

abstract：:To evaluate the effect of approximations in clinical analytical calculations performed by a treatment planning system (TPS) on dosimetric indices in intensity modulated proton therapy. TPS calculated dose distributions were compared with dose distributions as estimated by Monte Carlo (MC) simulations, calculated with ...

journal_title：Physics in medicine and biology

authors： Yepes P,Adair A,Grosshans D,Mirkovic D,Poenisch F,Titt U,Wang Q,Mohan R

更新日期：2018-02-09 00:00:00

abstract：:Microcalcification is one of the earliest and main indicators of breast cancer. Because dual-energy digital mammography could suppress the contrast between the adipose and glandular tissues of the breast, it is considered a promising technique that will improve the detection of microcalcification. In dual-energy digit...

journal_title：Physics in medicine and biology

authors： Mou X,Chen X,Sun L,Yu H,Ji Z,Zhang L

更新日期：2008-11-21 00:00:00

abstract：:As an x-ray beam goes through the human body, it will collect important information via interaction with tissues. Since this interaction is energy-sensitive, the state-of-the-art spectral CT technologies provide higher quality images of biological tissues with x-ray energy information (or spectral information). With e...

journal_title：Physics in medicine and biology

authors： Shi Z,Yang H,Cong W,Wang G

更新日期：2016-06-07 00:00:00

abstract：:A two-probe technique has been developed to measure 125I in the thyroid. In this technique simultaneous emissions from a source are detected as coincidence events between two probes rather than as a sum peak in a single probe (the sum peak method). The background count rate when counting coincidence events between pro...

journal_title：Physics in medicine and biology

authors： Burns PA,Peggie JR

更新日期：1980-05-01 00:00:00

abstract：:This work modified the commonly used Monte Carlo tool package GATE by developing a new 'multiPatchPET' system so that GATE users can easily simulate PET systems with irregular geometries. The motivation was to design a brain PET scanner with high sensitivity. It is known that compact PET scanners with a large solid co...

journal_title：Physics in medicine and biology

authors： Chen G,Weng F,Hong X,Tao W,Zhao Z,Peng Q,Huang Q

更新日期：2018-09-06 00:00:00

abstract：:The 50-year tenure of Physics in Medicine and Biology has coincided with some of the most important developments in radiological science, including the introduction of artificial radioactivity, computers and 3D imaging into medicine. These events have profoundly influenced the development of brachytherapy. Although it...

journal_title：Physics in medicine and biology

authors： Williamson JF

更新日期：2006-07-07 00:00:00