Posture-specific phantoms representing female and male adults in Monte Carlo-based simulations for radiological protection.

Abstract:

:Does the posture of a patient have an effect on the organ and tissue absorbed doses caused by x-ray examinations? This study aims to find the answer to this question, based on Monte Carlo (MC) simulations of commonly performed x-ray examinations using adult phantoms modelled to represent humans in standing as well as in the supine posture. The recently published FASH (female adult mesh) and MASH (male adult mesh) phantoms have the standing posture. In a first step, both phantoms were updated with respect to their anatomy: glandular tissue was separated from adipose tissue in the breasts, visceral fat was separated from subcutaneous fat, cartilage was segmented in ears, nose and around the thyroid, and the mass of the right lung is now 15% greater than the left lung. The updated versions are called FASH2_sta and MASH2_sta (sta = standing). Taking into account the gravitational effects on organ position and fat distribution, supine versions of the FASH2 and the MASH2 phantoms have been developed in this study and called FASH2_sup and MASH2_sup. MC simulations of external whole-body exposure to monoenergetic photons and partial-body exposure to x-rays have been made with the standing and supine FASH2 and MASH2 phantoms. For external whole-body exposure for AP and PA projection with photon energies above 30 keV, the effective dose did not change by more than 5% when the posture changed from standing to supine or vice versa. Apart from that, the supine posture is quite rare in occupational radiation protection from whole-body exposure. However, in the x-ray diagnosis supine posture is frequently used for patients submitted to examinations. Changes of organ absorbed doses up to 60% were found for simulations of chest and abdomen radiographs if the posture changed from standing to supine or vice versa. A further increase of differences between posture-specific organ and tissue absorbed doses with increasing whole-body mass is to be expected.

journal_name

Phys Med Biol

authors

Cassola VF,Kramer R,Brayner C,Khoury HJ

doi

10.1088/0031-9155/55/15/014

subject

Has Abstract

pub_date

2010-08-07 00:00:00

pages

4399-430

issue

15

eissn

0031-9155

issn

1361-6560

pii

S0031-9155(10)53815-6

journal_volume

55

pub_type

杂志文章
  • Percentile-specific computational phantoms constructed from ICRP mesh-type reference computational phantoms (MRCPs).

    abstract::Recently, the Task Group 103 of the International Commission on Radiological Protection (ICRP) has developed new mesh-type reference computational phantoms (MRCPs) for adult male and female. When compared to the current voxel-type reference computational phantoms in ICRP Publication 110, the MRCPs have several advanta...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aafcdb

    authors: Lee H,Yeom YS,Nguyen TT,Choi C,Han H,Shin B,Zhang X,Kim CH,Chung BS,Zankl M

    更新日期:2019-02-05 00:00:00

  • Investigation of real tissue water equivalent path lengths using an efficient dose extinction method.

    abstract::For proton therapy, an accurate conversion of CT HU to relative stopping power (RSP) is essential. Validation of the conversion based on real tissue samples is more direct than the current practice solely based on tissue substitutes and can potentially address variations over the population. Based on a novel dose exti...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa782c

    authors: Zhang R,Baer E,Jee KW,Sharp GC,Flanz J,Lu HM

    更新日期:2017-06-23 00:00:00

  • Minimizing the magnetic field effect in MR-linac specific QA-tests: the use of electron dense materials.

    abstract::To address the quality assurance (QA) of a MR-linac which is an MRI combined with a linear accelerator (linac), the traditional linac QA-tests need to be redesigned, since the presence of the static magnetic field in the MR-linac alters the electron trajectory. The latter causes the asymmetry in the dose kernel which ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/61/3/N50

    authors: van Zijp HM,van Asselen B,Wolthaus JW,Kok JM,de Vries JH,Ishakoglu K,Beld E,Lagendijk JJ,Raaymakers BW

    更新日期:2016-02-07 00:00:00

  • The experimental dose ranges influence the LETd dependency of the proton minimum RBE (RBEmin).

    abstract::Cell experiments have shown the proton relative biological effectiveness (RBE) to vary with dose and linear energy transfer (LET), which has led to development of variable RBE models. The RBE is normally estimated from two independent functions, the RBEmax and RBEmin, describing the extreme RBE at low and high doses. ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab369a

    authors: Rørvik E,Thörnqvist S,Ytre-Hauge KS

    更新日期:2019-09-23 00:00:00

  • A set cover approach to fast beam orientation optimization in intensity modulated radiation therapy for total marrow irradiation.

    abstract::The beam orientation optimization (BOO) problem in intensity modulated radiation therapy (IMRT) treatment planning is a nonlinear problem, and existing methods to obtain solutions to the BOO problem are time consuming due to the complex nature of the objective function and size of the solution space. These issues beco...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/56/17/014

    authors: Lee CH,Aleman DM,Sharpe MB

    更新日期:2011-09-07 00:00:00

  • Elastic modulus imaging: some exact solutions of the compressible elastography inverse problem.

    abstract::We consider several inverse problems motivated by elastography. Given the (possibly transient) displacement field measured everywhere in an isotropic, compressible, linear elastic solid, and given density rho, determine the Lamé parameters lambda and mu. We consider several special cases of this problem: (a) for mu kn...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/52/6/003

    authors: Barbone PE,Oberai AA

    更新日期:2007-03-21 00:00:00

  • Radiation dose factors for alpha-emitters in osteons and some considerations on dose non-uniformity ratios and relative distribution factors.

    abstract::Dose factors for locations within a tissue-filled cylindrical cavity bounded by an infinite medium of bone labelled with an alpha-emitter are calculated by means of a Monte Carlo procedure. The calculational approach is general and allows us to determine dose factors for specific distances or target volumes defined by...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/34/3/007

    authors: Polig E

    更新日期:1989-03-01 00:00:00

  • The design of anisotropic diffusion phantoms for the validation of diffusion weighted magnetic resonance imaging.

    abstract::Diffusion weighted magnetic resonance imaging offers a non-invasive tool to explore the three-dimensional structure of brain white matter in clinical practice. Anisotropic diffusion hardware phantoms are useful for the quantitative validation of this technique. This study provides guidelines on how to manufacture anis...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/53/19/009

    authors: Fieremans E,De Deene Y,Delputte S,Ozdemir MS,Achten E,Lemahieu I

    更新日期:2008-10-07 00:00:00

  • Dynamics of polymerization in polyacrylamide gel (PAG) dosimeters: (I) ageing and long-term stability.

    abstract::Few quantitative data are available on the kinetics of polymerization reactions in polymer gel (PAG) dosimeters and their long-term stability. Post-irradiation polymerization reactions have been found to continue for several weeks, posing questions regarding dosimeter stability and its achievement. In this paper we re...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/44/8/301

    authors: McJury M,Oldham M,Leach MO,Webb S

    更新日期:1999-08-01 00:00:00

  • Projection x-ray imaging with photon energy weighting: experimental evaluation with a prototype detector.

    abstract::The signal-to-noise ratio (SNR) in x-ray imaging can be increased using a photon counting detector which could allow for rejecting electronics noise and for weighting x-ray photons according to their energies. This approach, however, was not feasible for a long time because photon counting x-ray detectors with very hi...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/54/16/009

    authors: Shikhaliev PM

    更新日期:2009-08-21 00:00:00

  • Determination of fractional flow reserve (FFR) based on scaling laws: a simulation study.

    abstract::Fractional flow reserve (FFR) provides an objective physiological evaluation of stenosis severity. A technique that can measure FFR using only angiographic images would be a valuable tool in the cardiac catheterization laboratory. To perform this, the diseased blood flow can be measured with a first pass distribution ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/53/14/017

    authors: Wong JT,Molloi S

    更新日期:2008-07-21 00:00:00

  • 4D cone beam CT-based dose assessment for SBRT lung cancer treatment.

    abstract::The purpose of this research is to develop a 4DCBCT-based dose assessment method for calculating actual delivered dose for patients with significant respiratory motion or anatomical changes during the course of SBRT. To address the limitation of 4DCT-based dose assessment, we propose to calculate the delivered dose us...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/61/2/554

    authors: Cai W,Dhou S,Cifter F,Myronakis M,Hurwitz MH,Williams CL,Berbeco RI,Seco J,Lewis JH

    更新日期:2016-01-21 00:00:00

  • Optimizing functional parameter accuracy for breath-hold DCE-MRI of liver tumours.

    abstract::Dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) is a valuable tool for assessing treatment response to novel cancer therapeutics. With appropriate data acquisition, quantitative functional parameter estimates can be obtained by fitting a model to the data. This research focuses on applying a dual-input ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/54/7/023

    authors: Orton MR,Miyazaki K,Koh DM,Collins DJ,Hawkes DJ,Atkinson D,Leach MO

    更新日期:2009-04-07 00:00:00

  • Dielectric properties of ocular tissues in the supercooled and frozen states.

    abstract::Values of the relative permittivity and conductivity of the rabbit retina and lens have been measured between 10 MHz and 10 GHz over the temperature range 20 to -20 degrees C. As the temperature was lowered from 20 degrees C the dielectric parameters changed smoothly until -9 degrees C where freezing occurred. At this...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/30/9/009

    authors: Gabriel C,Grant EH

    更新日期:1985-09-01 00:00:00

  • Real-time prediction and gating of respiratory motion using an extended Kalman filter and Gaussian process regression.

    abstract::Motion-adaptive radiotherapy aims to deliver a conformal dose to the target tumour with minimal normal tissue exposure by compensating for tumour motion in real time. The prediction as well as the gating of respiratory motion have received much attention over the last two decades for reducing the targeting error of th...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/1/233

    authors: Bukhari W,Hong SM

    更新日期:2015-01-07 00:00:00

  • Recovering the triple coincidence of non-pure positron emitters in preclinical PET.

    abstract::Non-pure positron emitters, with their long half-lives, allow for the tracing of slow biochemical processes which cannot be adequately examined by the commonly used short-lived positron emitters. Most of these isotopes emit high-energy cascade gamma rays in addition to positron decay that can be detected and create a ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/61/5/1904

    authors: Lin HH,Chuang KS,Chen SY,Jan ML

    更新日期:2016-03-07 00:00:00

  • Online compensation for target motion with scanned particle beams: simulation environment.

    abstract::Target motion is one of the major limitations of each high precision radiation therapy. Using advanced active beam delivery techniques, such as the magnetic raster scanning system for particle irradiation, the interplay between time-dependent beam and target position heavily distorts the applied dose distribution. Thi...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/49/14/001

    authors: Li Q,Groezinger SO,Haberer T,Rietzel E,Kraft G

    更新日期:2004-07-21 00:00:00

  • Accounting for range uncertainties in the optimization of intensity modulated proton therapy.

    abstract::Treatment plans optimized for intensity modulated proton therapy (IMPT) may be sensitive to range variations. The dose distribution may deteriorate substantially when the actual range of a pencil beam does not match the assumed range. We present two treatment planning concepts for IMPT which incorporate range uncertai...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/52/10/009

    authors: Unkelbach J,Chan TC,Bortfeld T

    更新日期:2007-05-21 00:00:00

  • An estimation of noise levels in HMPAO RCBF SPECT images using simulation and phantom data; comparison with results obtained from repeated normal controls.

    abstract::The purpose of this work was to determine noise levels in HMPAO RCBF SPECT images. Eight simulated images of a uniform sphere of activity were made at each of three different count levels. Three images of the Amersham brain phantom were obtained at each of three count levels, roughly corresponding to the simulation le...

    journal_title:Physics in medicine and biology

    pub_type: 临床试验,杂志文章

    doi:10.1088/0031-9155/39/5/006

    authors: Houston AS,Kemp PM,Griffiths PT,MacLeod MA

    更新日期:1994-05-01 00:00:00

  • Fast calibration of SPECT monolithic scintillation detectors using un-collimated sources.

    abstract::Monolithic scintillation detectors for positron emission tomography and single-photon emission computed tomography (SPECT) imaging have many advantages over pixelated detectors. The use of monolithic crystals allows for reducing the scintillator cost per unit volume and increasing the sensitivity along with the energy...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/58/14/4807

    authors: España S,Deprez K,Van Holen R,Vandenberghe S

    更新日期:2013-07-21 00:00:00

  • Comparison of Geant4 multiple Coulomb scattering models with theory for radiotherapy protons.

    abstract::Usually, Monte Carlo models are validated against experimental data. However, models of multiple Coulomb scattering (MCS) in the Gaussian approximation are exceptional in that we have theories which are probably more accurate than the experiments which have, so far, been done to test them. In problems directly sensiti...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa6ce3

    authors: Makarova A,Gottschalk B,Sauerwein W

    更新日期:2017-07-06 00:00:00

  • Classification of movement intention by spatially filtered electromagnetic inverse solutions.

    abstract::We couple standardized low-resolution electromagnetic tomography, an inverse solution for electroencephalography (EEG) and the common spatial pattern, which is here conceived as a data-driven beamformer, to classify the benchmark BCI (brain-computer interface) competition 2003, data set IV. The data set is from an exp...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/51/8/002

    authors: Congedo M,Lotte F,Lécuyer A

    更新日期:2006-04-21 00:00:00

  • Spectral phase-based automatic calibration scheme for swept source-based optical coherence tomography systems.

    abstract::The automatic calibration in Fourier-domain optical coherence tomography (FD-OCT) systems allows for high resolution imaging with precise depth ranging functionality in many complex imaging scenarios, such as microsurgery. However, the accuracy and speed of the existing automatic schemes are limited due to the functio...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/61/21/7652

    authors: Ratheesh KM,Seah LK,Murukeshan VM

    更新日期:2016-11-07 00:00:00

  • Motion correction of respiratory-gated PET images using deep learning based image registration framework.

    abstract::Artifacts caused by patient breathing and movement during PET data acquisition affect image quality. Respiratory gating is commonly used to gate the list-mode PET data into multiple bins over a respiratory cycle. Non-rigid registration of respiratory-gated PET images can reduce motion artifacts and preserve count stat...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab8688

    authors: Li T,Zhang M,Qi W,Asma E,Qi J

    更新日期:2020-07-30 00:00:00

  • The feasibility of using poroelastographic techniques for distinguishing between normal and lymphedematous tissues in vivo.

    abstract::Lymphedema is a common condition involving an abnormal accumulation of lymphatic fluid in the interstitial space that causes swelling, most often in the arm(s) and leg(s). Lymphedema is a significant lifelong concern that can be congenital or develop following cancer treatment or cancer metastasis. Common methods of e...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/52/21/013

    authors: Righetti R,Garra BS,Mobbs LM,Kraemer-Chant CM,Ophir J,Krouskop TA

    更新日期:2007-11-07 00:00:00

  • The use of narrowband ultrasound for characterization of tissue in a thin layer.

    abstract::Most tissue characterization methods use RF data originating from backscattering processes in the insonified tissue. Characterization of the tissue of a thin layer (e.g., an artery wall) poses problems because of the small amount of data available. The tissue layer may be so thin that there are no RF data that are not...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/36/10/002

    authors: Linssen FM,Hoeks AP,Brands PJ

    更新日期:1991-10-01 00:00:00

  • Delivery time comparison for intensity-modulated radiation therapy with/without flattening filter: a planning study.

    abstract::The treatment delivery time of intensity-modulated radiation therapy (IMRT) with a multileaf collimator (MLC) is generally longer than that of conventional radiotherapy. In theory, removing the flattening filter from the treatment head may reduce the beam-on time by enhancing the output dose rate, and then reduce the ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/49/8/011

    authors: Fu W,Dai J,Hu Y,Han D,Song Y

    更新日期:2004-04-21 00:00:00

  • A spectral approach to ultrasonic scattering from human tissue: methods, objectives and backscattering measurements.

    abstract::The dearth of information on the physical processes involved in the propagation of ultrasound in tissue and the growing need for such information are discussed. The physical nature of the ultrasonic diagnostic process in considered in terms of a wave phenomenon and the limitations and advantages of frequency spectral ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/20/5/009

    authors: Chivers RC,Hill CR

    更新日期:1975-09-01 00:00:00

  • A complete distortion correction for MR images: II. Rectification of static-field inhomogeneities by similarity-based profile mapping.

    abstract::Radiotherapy treatment planning relies on the use of geometrically correct images. This paper presents a fully automatic tool for correcting MR images for the effects of B(0) inhomogeneities. The post-processing method is based on the gradient-reversal technique of Chang and Fitzpatrick (1992 IEEE Trans. Med. Imaging ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/50/11/014

    authors: Reinsberg SA,Doran SJ,Charles-Edwards EM,Leach MO

    更新日期:2005-06-07 00:00:00

  • Optimization of tumour control probability for heterogeneous tumours in fractionated radiotherapy treatment protocols.

    abstract::We find the dose distribution that maximizes the tumour control probability (TCP) for a fixed mean tumour dose per fraction. We consider a heterogeneous tumour volume having a radiation response characterized by the linear quadratic model with heterogeneous radiosensitivity and repopulation rate that may vary in time....

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/49/3/005

    authors: Levin-Plotnik D,Hamilton RJ

    更新日期:2004-02-07 00:00:00