Ionization chamber correction factors for MR-linacs.

Abstract:

:Previously, readings of air-filled ionization chambers have been described as being influenced by magnetic fields. To use these chambers for dosimetry in magnetic resonance guided radiotherapy (MRgRT), this effect must be taken into account by introducing a correction factor k B. The purpose of this study is to systematically investigate k B for a typical reference setup for commercially available ionization chambers with different magnetic field strengths. The Monte Carlo simulation tool EGSnrc was used to simulate eight commercially available ionization chambers in magnetic fields whose magnetic flux density was in the range of 0-2.5 T. To validate the simulation, the influence of the magnetic field was experimentally determined for a PTW30013 Farmer-type chamber for magnetic flux densities between 0 and 1.425 T. Changes in the detector response of up to 8% depending on the magnetic flux density, on the chamber geometry and on the chamber orientation were obtained. In the experimental setup, a maximum deviation of less than 2% was observed when comparing measured values with simulated values. Dedicated values for two MR-linac systems (ViewRay MRIdian, ViewRay Inc, Cleveland, United States, 0.35 T/ 6 MV and Elekta Unity, Elekta AB, Stockholm, Sweden, 1.5 T/7 MV) were determined for future use in reference dosimetry. Simulated values for thimble-type chambers are in good agreement with experiments as well as with the results of previous publications. After further experimental validation, the results can be considered for definition of standard protocols for purposes of reference dosimetry in MRgRT.

journal_name

Phys Med Biol

authors

Pojtinger S,Dohm OS,Kapsch RP,Thorwarth D

doi

10.1088/1361-6560/aac4f2

subject

Has Abstract

pub_date

2018-06-07 00:00:00

pages

11NT03

issue

11

eissn

0031-9155

issn

1361-6560

journal_volume

63

pub_type

杂志文章
  • Determination of fractional flow reserve (FFR) based on scaling laws: a simulation study.

    abstract::Fractional flow reserve (FFR) provides an objective physiological evaluation of stenosis severity. A technique that can measure FFR using only angiographic images would be a valuable tool in the cardiac catheterization laboratory. To perform this, the diseased blood flow can be measured with a first pass distribution ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/53/14/017

    authors: Wong JT,Molloi S

    更新日期:2008-07-21 00:00:00

  • Medical staff extremity dosimetry in CT fluoroscopy: an anthropomorphic hand voxel phantom study.

    abstract::This work aims to contribute to the study of the radiation dose distribution delivered to the hands of medical staff members during a general computed tomographic (CT) fluoroscopic guided procedure. In this study, both Monte Carlo simulations and measurements were performed. For free-in-air and computed tomography dos...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/58/16/5433

    authors: Figueira C,Becker F,Blunck C,DiMaria S,Baptista M,Esteves B,Paulo G,Santos J,Teles P,Vaz P

    更新日期:2013-08-21 00:00:00

  • Effect of blood perfusion on the ablation of liver parenchyma with high-intensity focused ultrasound.

    abstract::This paper discusses the effect of blood perfusion on the ablation of rat liver tissue with high-intensity focused ultrasound (HIFU). For this study a practical method has been developed, in which the liver blood flow can be reduced by ligation of the hepatic artery and portal vein. During the treatment the rat liver ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/38/11/011

    authors: Chen L,ter Haar G,Hill CR,Dworkin M,Carnochan P,Young H,Bensted JP

    更新日期:1993-11-01 00:00:00

  • Extended three-compartment model for the transport and distribution of Hippuran.

    abstract::The distribution and transport of Hippuran is discussed. The activity leaving both kidneys has been calculated and compared with the bladder activity. It is shown that the Impulse Response Function of the ureter and bladder may be obtained by deconvolution, and data are presented relating to studies on one patient. ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/26/2/002

    authors: Knesaurek K,Spaventi S

    更新日期:1981-03-01 00:00:00

  • A validated Geant4 model of a whole-body PET scanner with four-layer DOI detectors.

    abstract::The purpose of this work is to develop a validated Geant4 simulation model of a whole-body prototype PET scanner constructed from the four-layer depth-of-interaction detectors developed at the National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Japan. T...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/abaa24

    authors: Ahmed AM,Chacon A,Rutherford H,Akamatsu G,Mohammadi A,Nishikido F,Tashima H,Yoshida E,Yamaya T,Franklin DR,Rosenfeld A,Guatelli S,Safavi-Naeini M

    更新日期:2020-12-18 00:00:00

  • Comparison of manual and automatic segmentation methods for brain structures in the presence of space-occupying lesions: a multi-expert study.

    abstract::The purpose of this work was to characterize expert variation in segmentation of intracranial structures pertinent to radiation therapy, and to assess a registration-driven atlas-based segmentation algorithm in that context. Eight experts were recruited to segment the brainstem, optic chiasm, optic nerves, and eyes, o...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/56/14/021

    authors: Deeley MA,Chen A,Datteri R,Noble JH,Cmelak AJ,Donnelly EF,Malcolm AW,Moretti L,Jaboin J,Niermann K,Yang ES,Yu DS,Yei F,Koyama T,Ding GX,Dawant BM

    更新日期:2011-07-21 00:00:00

  • Experimental validation of Monte Carlo calculations with a voxelized Rando-Alderson phantom: a study on influence parameters.

    abstract::The development and improvement of techniques for an accurate dose assessment in medical physics is an important task. In this study, we focus on the validation of Monte Carlo calculations, by comparing organ doses assessed experimentally with thermoluminescent detectors in the Rando-Alderson phantom with doses calcul...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/53/20/018

    authors: Struelens L,Vanhavere F,Smans K

    更新日期:2008-10-21 00:00:00

  • Experimental evaluation of fiber-interspaced antiscatter grids for large patient imaging with digital x-ray systems.

    abstract::Radiographic imaging of large patients is compromised by x-ray scatter. Optimization of digital x-ray imaging systems used for projection radiography requires the use of the best possible antiscatter grid. The performance of antiscatter grids used in conjunction with digital x-ray imaging systems can be characterized ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/52/16/010

    authors: Fetterly KA,Schueler BA

    更新日期:2007-08-21 00:00:00

  • Radiofrequency and microwave dielectric properties of aqueous cryoprotectant agents: dimethyl sulphoxide and 2,3-butanediol.

    abstract::Earlier work on the dielectric properties of cryoprotectant agents is extended using a modified measuring cell and method of data reduction yielding results more efficiently over a temperature range from -75 to +25 degrees C at frequencies from 27 MHz to 3 GHz. Dimethyl sulphoxide and butanediol are investigated at lo...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/43/10/011

    authors: Evans S,bin Azeman A

    更新日期:1998-10-01 00:00:00

  • Effect of 176Lu background on singles transmission for LSO-based PET cameras.

    abstract::We explore how the radioactive background from naturally occurring 176Lu affects single photon transmission imaging for lutetium orthosilicate (LSO) scintillator-based PET cameras by estimating the transmission noise equivalent count rate (NECR) including this background. Assuming a typical PET camera geometry (80 cm ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/47/19/307

    authors: Huber JS,Moses WW,Jones WF,Watson CC

    更新日期:2002-10-07 00:00:00

  • Scatter compensation methods in 3D iterative SPECT reconstruction: a simulation study.

    abstract::Effects of different scatter compensation methods incorporated in fully 3D iterative reconstruction are investigated. The methods are: (i) the inclusion of an 'ideal scatter estimate' (ISE); (ii) like (i) but with a noiseless scatter estimate (ISE-NF); (iii) incorporation of scatter in the point spread function during...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/42/8/011

    authors: Beekman FJ,Kamphuis C,Frey EC

    更新日期:1997-08-01 00:00:00

  • New compensator design options for charged-particle radiotherapy.

    abstract::The purpose of this investigation is to propose new compensator design strategies for protons and heavier particles which are based on pencil-beam (PB) dose calculations and which significantly reduce the dose to tissues downstream from the target, yet provide acceptable target coverage under conditions of patient mot...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/42/7/005

    authors: Petti PL

    更新日期:1997-07-01 00:00:00

  • Robust principal component analysis-based four-dimensional computed tomography.

    abstract::The purpose of this paper for four-dimensional (4D) computed tomography (CT) is threefold. (1) A new spatiotemporal model is presented from the matrix perspective with the row dimension in space and the column dimension in time, namely the robust PCA (principal component analysis)-based 4D CT model. That is, instead o...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/56/11/002

    authors: Gao H,Cai JF,Shen Z,Zhao H

    更新日期:2011-06-07 00:00:00

  • Measurement of the response of Gd2O2S:Tb phosphor to 6 MV x-rays.

    abstract::The phosphor GdO2S:Tb is widely used in camera-based electronic portal imaging devices (EPIDs). There is considerable interest in the application of EPIDs to dosimetry and the verification of intensity modulated radiation therapy produced by dynamic multileaf collimation (DMLC). This paper presents direct measurement ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/46/2/317

    authors: Glendinning AG,Hunt SG,Bonnett DE

    更新日期:2001-02-01 00:00:00

  • Computation of bremsstrahlung X-ray spectra and comparison with spectra measured with a Ge(Li) detector.

    abstract::A method of computing theoretical X-ray spectra in the range 30-150 kV is presented. The theoretical spectra are compared with constant potential, high resolution spectra from a tungsten target measured with a Ge(Li) detector, for a range of target angles, tube voltage and filtrations. Above 100 kV the spectra were al...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/24/3/002

    authors: Birch R,Marshall M

    更新日期:1979-05-01 00:00:00

  • Estimating cancer risk from dental cone-beam CT exposures based on skin dosimetry.

    abstract::The aim of this study was to measure entrance skin doses on patients undergoing cone-beam computed tomography (CBCT) examinations, to establish conversion factors between skin and organ doses, and to estimate cancer risk from CBCT exposures. 266 patients (age 8-83) were included, involving three imaging centres. CBCT ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/59/14/3877

    authors: Pauwels R,Cockmartin L,Ivanauskaité D,Urbonienė A,Gavala S,Donta C,Tsiklakis K,Jacobs R,Bosmans H,Bogaerts R,Horner K,SEDENTEXCT Project Consortium.

    更新日期:2014-07-21 00:00:00

  • Single spectrum three-material decomposition with grating-based x-ray phase-contrast CT.

    abstract::Grating-based x-ray phase-contrast imaging provides three simultaneous image channels originating from a single image acquisition. While the phase signal provides direct access to the electron density in tomography, there is additional information on sub-resolutional structural information which is called dark-field s...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab9704

    authors: Braig EM,Pfeiffer D,Willner M,Sellerer T,Taphorn K,Petrich C,Scholz J,Petzold L,Birnbacher L,Dierolf M,Pfeiffer F,Herzen J

    更新日期:2020-09-18 00:00:00

  • A robust state-space kinetics-guided framework for dynamic PET image reconstruction.

    abstract::Dynamic PET image reconstruction is a challenging issue due to the low SNR and the large quantity of spatio-temporal data. We propose a robust state-space image reconstruction (SSIR) framework for activity reconstruction in dynamic PET. Unlike statistically-based frame-by-frame methods, tracer kinetic modeling is inco...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/56/8/010

    authors: Tong S,Alessio AM,Kinahan PE,Liu H,Shi P

    更新日期:2011-04-21 00:00:00

  • Residual motion compensation in ECG-gated interventional cardiac vasculature reconstruction.

    abstract::Three-dimensional reconstruction of cardiac vasculature from angiographic C-arm CT (rotational angiography) data is a major challenge. Motion artefacts corrupt image quality, reducing usability for diagnosis and guidance. Many state-of-the-art approaches depend on retrospective ECG-gating of projection data for image ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/58/11/3717

    authors: Schwemmer C,Rohkohl C,Lauritsch G,Müller K,Hornegger J

    更新日期:2013-06-07 00:00:00

  • Detector arrangement and sampling characteristics in rotary positron-emission computed tomography.

    abstract::A rotary positron-emission computed tomography system has been proposed in which detectors are mounted unequally spaced on a ring, so as to provide fine and uniform linear sampling during a 360 degree rotation of the ring around its centre. The usefulness of a simple iterative method for searching for a suitable arran...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/26/3/011

    authors: Yamamoto M

    更新日期:1981-05-01 00:00:00

  • Optimization of multiply acquired magnetic flux density B(z) using ICNE-Multiecho train in MREIT.

    abstract::The aim of magnetic resonance electrical impedance tomography (MREIT) is to visualize the electrical properties, conductivity or current density of an object by injection of current. Recently, the prolonged data acquisition time when using the injected current nonlinear encoding (ICNE) method has been advantageous for...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/55/9/021

    authors: Nam HS,Kwon OI

    更新日期:2010-05-07 00:00:00

  • The dose--response relation for rat spinal cord paralysis analyzed in terms of the effective size of the functional subunit.

    abstract::Radiobiological models for estimating normal tissue complication probability (NTCP) are increasingly used in order to quantify or optimize the clinical outcome of radiation therapy. A good NTCP model should fulfill at least the following two requirements: (a) it should predict the sigmoid shape of the corresponding do...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/53/22/016

    authors: Adamus-Górka M,Mavroidis P,Brahme A,Lind BK

    更新日期:2008-11-21 00:00:00

  • Image-based view-angle independent cardiorespiratory motion gating and coronary sinus catheter tracking for x-ray-guided cardiac electrophysiology procedures.

    abstract::Determination of the cardiorespiratory phase of the heart has numerous applications during cardiac imaging. In this article we propose a novel view-angle independent near-real time cardiorespiratory motion gating and coronary sinus (CS) catheter tracking technique for x-ray fluoroscopy images that are used to guide ca...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/20/8087

    authors: Panayiotou M,Rhode KS,King AP,Ma Y,Cooklin M,O'Neill M,Gill J,Rinaldi CA,Housden RJ

    更新日期:2015-10-21 00:00:00

  • A thin target approach for portal imaging in medical accelerators.

    abstract::A new thin-target method (patent pending) is described for portal imaging with low-energy (tens of keV) photons from a medical linear accelerator operating in a special mode. Low-energy photons are usually produced in the accelerator target, but are absorbed by the target and flattening filter, both made of medium- or...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/43/8/016

    authors: Tsechanski A,Bielajew AF,Faermann S,Krutman Y

    更新日期:1998-08-01 00:00:00

  • First experimental evidence of the feasibility of multi-color magnetic particle imaging.

    abstract::Magnetic particle imaging is a new approach to visualizing magnetic nanoparticles. It is capable of 3D real-time in vivo imaging of particles injected into the blood stream and is a candidate for medical imaging applications. To date, only one particle type has been imaged at a time, however, the ability to separate s...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/5/1775

    authors: Rahmer J,Halkola A,Gleich B,Schmale I,Borgert J

    更新日期:2015-03-07 00:00:00

  • Posture-specific phantoms representing female and male adults in Monte Carlo-based simulations for radiological protection.

    abstract::Does the posture of a patient have an effect on the organ and tissue absorbed doses caused by x-ray examinations? This study aims to find the answer to this question, based on Monte Carlo (MC) simulations of commonly performed x-ray examinations using adult phantoms modelled to represent humans in standing as well as ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/55/15/014

    authors: Cassola VF,Kramer R,Brayner C,Khoury HJ

    更新日期:2010-08-07 00:00:00

  • PETSIM: Monte Carlo simulation of all sensitivity and resolution parameters of cylindrical positron imaging systems.

    abstract::Monte Carlo simulation techniques are applied to track the annihilation photons from positron decay, and store the photon histories. Reasonably realistic models of the isotope distribution in the brain and heart during typical PET studies, as well as the traditional phantoms used for measuring PET scanner performance ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/37/3/017

    authors: Thompson CJ,Moreno-Cantu J,Picard Y

    更新日期:1992-03-01 00:00:00

  • Accurate Monte Carlo calculations of the combined attenuation and build-up factors, for energies (20-1500 keV) and distances (0-10 cm) relevant in brachytherapy.

    abstract::The combined build-up and attenuation factor, B exp (-mu r), of point isotropic photon sources in a water medium has been calculated using the Monte Carlo method, for energies (20-1500 keV) and distances (1-10 cm) relevant in brachytherapy. For the transport of photons and electrons, up-to-date and self-consistent tot...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/36/6/005

    authors: Angelopoulos A,Perris A,Sakellariou K,Sakelliou L,Sarigiannis K,Zarris G

    更新日期:1991-06-01 00:00:00

  • Significance of background optical properties, time-resolved information and optode arrangement in diffuse optical imaging of term neonates.

    abstract::The significance of accurate knowledge of background optical properties and time-resolved information in reconstructing images of hemodynamic changes in the neonatal brain from diffuse optical imaging data was studied using Monte Carlo (MC) simulation. A segmented anatomical magnetic resonance (MR) image and literatur...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/54/3/005

    authors: Heiskala J,Hiltunen P,Nissilä I

    更新日期:2009-02-07 00:00:00

  • Investigation of systematic uncertainties in Monte Carlo-calculated beam quality correction factors.

    abstract::Modern Monte Carlo codes allow for the calculation of ion chamber specific beam quality correction factors k(Q), which are needed for dosimetry in radiotherapy. While statistical (type A) uncertainties of the calculated data can be minimized sufficiently, the influence of systematic (type B) uncertainties is mostly un...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/55/16/S04

    authors: Wulff J,Heverhagen JT,Zink K,Kawrakow I

    更新日期:2010-08-21 00:00:00