Investigation of systematic uncertainties in Monte Carlo-calculated beam quality correction factors.

abstract：:In response to the recognized fragility of reactor-produced (99)Mo supply, direct production of (99m)Tc via (100)Mo(p,2n)(99m)Tc reaction using medical cyclotrons has been investigated. However, due to the existence of other Molybdenum (Mo) isotopes in the target, in parallel with (99m)Tc, other technetium (Tc) radioa...

journal_title：Physics in medicine and biology

authors： Hou X,Tanguay J,Buckley K,Schaffer P,Bénard F,Ruth TJ,Celler A

更新日期：2016-01-21 00:00:00

abstract：:Cone-beam computed tomography (CBCT) has rapidly become a clinically useful imaging modality for image-guided radiation therapy. Unfortunately, CBCT images of the thorax are susceptible to artefacts due to scattered photons, beam hardening, lag in data acquisition, and respiratory motion during a slow scan. These limi...

journal_title：Physics in medicine and biology

authors： Disher B,Hajdok G,Wang A,Craig J,Gaede S,Battista JJ

更新日期：2013-06-21 00:00:00

abstract：:To evaluate a commercial synthetic CT (syn-CT) software for use in prostate radiotherapy. Twenty-five prostate patients underwent CT and MR simulation scans in treatment position on a 3T MR scanner. A commercially available MR protocol was used that included a T2w turbo spin-echo sequence for soft-tissue contrast and ...

journal_title：Physics in medicine and biology

authors： Tyagi N,Fontenla S,Zhang J,Cloutier M,Kadbi M,Mechalakos J,Zelefsky M,Deasy J,Hunt M

更新日期：2017-04-21 00:00:00

abstract：:Three-dimensional reconstruction of coronary arteries can be performed during x-ray-guided interventions by gated reconstruction from a rotational coronary angiography sequence. Due to imperfect gating and cardiac or breathing motion, the heart's motion state might not be the same in all projections used for the recon...

journal_title：Physics in medicine and biology

authors： Hansis E,Schäfer D,Dössel O,Grass M

更新日期：2008-07-21 00:00:00

abstract：:As automation in radiation oncology becomes more common, it is important to determine which algorithms are equivalent for a given workflow. Often, algorithm comparisons are performed in isolation; however, clinical context can provide valuable insight into the importance of algorithm features and error magnification i...

journal_title：Physics in medicine and biology

authors： Weppler S,Schinkel C,Kirkby C,Smith W

更新日期：2020-09-28 00:00:00

abstract：:Therapy with helium ions is currently receiving significantly increasing interest because helium ions have a sharper penumbra than protons and undergo less fragmentation than carbon ions and thus require less complicated dose calculations. For any ion of interest in hadron therapy, the accuracy of dose delivery is lim...

journal_title：Physics in medicine and biology

authors： Ozoemelam I,van der Graaf E,Brandenburg S,Dendooven P

更新日期：2019-12-05 00:00:00

abstract：:Cylindrical ionization chambers with varying radii have been used to determine the displacement effect at distances between 10 mm and 40 mm from 60Co and 192Ir brachytherapy sources. Agreement with published values of the displacement factor for external 60Co beams is obtained. The shift between the centre of the ioni...

journal_title：Physics in medicine and biology

authors： Tölli H,Johansson KA

更新日期：1993-10-01 00:00:00

abstract：:Over the past few years there has been much interest in the development of three-dimensional dosimeters to determine the complex absorbed dose distribution in modern radiotherapy techniques such as IMRT and IGRT. In routine methods used for three-dimensional dosimetry, polymer gels are commonly used. Recently, a novel...

journal_title：Physics in medicine and biology

authors： Mostaar A,Hashemi B,Zahmatkesh MH,Aghamiri SM,Mahdavi SR

更新日期：2010-02-07 00:00:00

abstract：:Novel x-ray medical imaging sensors, such as photon counting detectors (PCDs) and large area CCD and CMOS cameras can involve irregular and/or sparse sampling of the detector plane. Application of such detectors to CT involves undersampling that is markedly different from the commonly considered case of sparse angular...

journal_title：Physics in medicine and biology

authors： Sisniega A,Zbijewski W,Stayman JW,Xu J,Taguchi K,Fredenberg E,Lundqvist M,Siewerdsen JH

更新日期：2016-01-07 00:00:00

abstract：:Target motion is one of the major limitations of each high precision radiation therapy. Using advanced active beam delivery techniques, such as the magnetic raster scanning system for particle irradiation, the interplay between time-dependent beam and target position heavily distorts the applied dose distribution. Thi...

journal_title：Physics in medicine and biology

authors： Li Q,Groezinger SO,Haberer T,Rietzel E,Kraft G

更新日期：2004-07-21 00:00:00

abstract：:For image-guided radiotherapy (IGRT) systems based on cone beam CT (CBCT) integrated into a linear accelerator, the reproducible alignment of imager to x-ray source is critical to the registration of both the x-ray-volumetric image with the megavoltage (MV) beam isocentre and image sharpness. An enhanced method of det...

journal_title：Physics in medicine and biology

authors： Sykes JR,Lindsay R,Dean CJ,Brettle DS,Magee DR,Thwaites DI

更新日期：2008-10-07 00:00:00

abstract：:Monte Carlo simulation with PENELOPE (version 2003) is applied to calculate Leksell Gamma Knife dose distributions for heterogeneous phantoms. The usual spherical water phantom is modified with a spherical bone shell simulating the skull and an air-filled cube simulating the frontal or maxillary sinuses. Different sim...

journal_title：Physics in medicine and biology

authors： Al-Dweri FM,Rojas EL,Lallena AM

更新日期：2005-12-07 00:00:00

abstract：:An overview of the theory of 4D image reconstruction for emission tomography is given along with a review of the current state of the art, covering both positron emission tomography and single photon emission computed tomography (SPECT). By viewing 4D image reconstruction as a matter of either linear or non-linear par...

journal_title：Physics in medicine and biology

authors： Reader AJ,Verhaeghe J

更新日期：2014-11-21 00:00:00

abstract：:The behaviour of scatter dose in 4 and 8 MV wedged x-ray beams has been studied by calculating scatter-to-primary dose ratios (SPR) and comparing these with SPR for non-wedged beams. On the central axis the SPR for wedged and non-wedged beams differ only by a few per cent, a difference which increases slightly with we...

journal_title：Physics in medicine and biology

authors： Brown LH,Siddon RL,Bjärngard BE

更新日期：1987-10-01 00:00:00

abstract：:Doxorubicin (Dox) is a well-established chemotherapeutic agent, however it has limited efficacy in treating brain malignancies due to the presence of the blood-brain barrier (BBB). Recent preclinical studies have demonstrated that focused ultrasound induced BBB disruption (BBBD) enables efficient delivery of Dox to th...

journal_title：Physics in medicine and biology

authors： Nhan T,Burgess A,Lilge L,Hynynen K

更新日期：2014-10-21 00:00:00

abstract：:Absorbed dose values were determined under the reference conditions in a phantom irradiated by high-energy photon beams with quality varying between 60Co gamma rays and 25 MV X-rays, using four commonly employed types of ionisation chamber. The ionisation chamber readings were converted to absorbed dose values applyin...

journal_title：Physics in medicine and biology

authors： Mijnheer BJ,Wittkämper FW

更新日期：1986-04-01 00:00:00

abstract：:Quantitative Yttrium-90 ((90)Y) bremsstrahlung single photon emission computed tomography (SPECT) imaging has shown great potential to provide reliable estimates of (90)Y activity distribution for targeted radionuclide therapy dosimetry applications. One factor that potentially affects the reliability of the activity ...

journal_title：Physics in medicine and biology

authors： Rong X,Du Y,Frey EC

更新日期：2012-06-21 00:00:00

abstract：:We report the first experimental soft-tissue phase-contrast tomography results using a conventional x-ray tube source, with a millimeter-sized focal spot. The setup is based on a Talbot-Lau grating interferometer operated at a mean energy of 28 keV. We present three-dimensional ex vivo images of a chicken heart sample...

journal_title：Physics in medicine and biology

authors： Bech M,Jensen TH,Feidenhans'l R,Bunk O,David C,Pfeiffer F

更新日期：2009-05-07 00:00:00

abstract：:Radionuclides which decay by electron capture accompanied by Auger electron cascades, or by beta emission are thought to be excessively damaging when incorporated into the molecular structure of mammalian cell nuclei and thereby pose a radiation hazard which is not assessable by conventional dosimetry. Survival data, ...

journal_title：Physics in medicine and biology

authors： Younis AR,Watt DE

更新日期：1989-07-01 00:00:00

abstract：:In recent years, optical techniques based on diffusion approximation have demonstrated their ability to gain rich spectral information about bone. However, these methods normally assume homogeneity, while cancellous bone and marrow form a highly heterogeneous two-phase medium. This paper studies the limitations of thi...

journal_title：Physics in medicine and biology

authors： Margallo-Balbás E,Taroni P,Pifferi A,Koolstra JH,v Ruijven LJ,French PJ

更新日期：2010-09-07 00:00:00

abstract：:The origin of photons emitted in optical fibres under proton irradiation has been attributed to either entirely Čerenkov radiation or light consisting of fluorescence with a substantial amount of Čerenkov radiation. The source of the light emission is assessed in order to understand why the signal from optical fibres ...

journal_title：Physics in medicine and biology

authors： Brage Christensen J,Almhagen E,Nyström H,Andersen CE

更新日期：2018-03-09 00:00:00

abstract：:We experimentally investigated the SPECT recovery of I-131 activity in multiple spheres located simultaneously at different locations within a cylindrical phantom that had an elliptical cross section. The sphere volumes ranged from 209 cc down to 4.2 cc. A Prism 3000 camera and two types of parallel-hexagonal-hole col...

journal_title：Physics in medicine and biology

authors： Koral KF,Yendiki A,Dewaraja YK

更新日期：2007-02-07 00:00:00

abstract：:A method for the calculation of absorbed dose distributions of arbitrarily shaped electron beams is presented. Isodose distributions and output factors of treatment fields can be predicted with good accuracy, without the need for any dose measurement in the actual field. A Gaussian pencil beam model is employed with t...

journal_title：Physics in medicine and biology

authors： Bruinvis IA,Van Amstel A,Elevelt AJ,Van der Laarse R

更新日期：1983-06-01 00:00:00

abstract：:Chronic liver disease (CLD) is currently one of the major causes of death worldwide. If not treated, it may lead to cirrhosis, hepatic carcinoma and death. Ultrasound (US) shear wave elastography (SWE) is a relatively new, popular, non-invasive technique among radiologists. Although many studies have been published va...

journal_title：Physics in medicine and biology

authors： Kagadis GC,Drazinos P,Gatos I,Tsantis S,Papadimitroulas P,Spiliopoulos S,Karnabatidis D,Theotokas I,Zoumpoulis P,Hazle JD

更新日期：2020-11-05 00:00:00

abstract：:By the end of 2002, 33 398 patients worldwide had been treated with proton radiotherapy, 10 829 for eye diseases. The dose prediction algorithms used today for ocular proton therapy treatment planning rely on parameterizations of measured proton dose distributions, i.e., broad-beam and pencil-beam techniques, whose pr...

journal_title：Physics in medicine and biology

authors： Newhauser W,Koch N,Hummel S,Ziegler M,Titt U

更新日期：2005-11-21 00:00:00

abstract：:K-edge subtraction (KES) imaging is a technique able to map a specific element such as e.g. a contrast agent within the tissues, by exploiting the sharp rise of its absorption coefficient at the K-edge energy. Whereas mainly explored at synchrotron radiation sources, the energy discrimination properties of modern x-ra...

journal_title：Physics in medicine and biology

authors： Brun F,Di Trapani V,Albers J,Sacco P,Dreossi D,Brombal L,Rigon L,Longo R,Mittone A,Dullin C,Bravin A,Delogu P

更新日期：2020-03-06 00:00:00

abstract：:The feasibility is demonstrated of a numerical method to calculate dose deposition by broad high-energy electron beams in homogeneous matter or in heterogeneous matter in which the heterogeneities are arranged in slabs perpendicular to the beam axis. The method is based only on the basic physical interaction processes...

journal_title：Physics in medicine and biology

authors： Huizenga H,Storchi PR

更新日期：1989-10-01 00:00:00

abstract：:The values of the replacement correction factors (P(repl), or in the IAEA's notation p(dis)p(cav)) used for cylindrical chambers in high-energy photon beams represent one of the most significant differences between the AAPM and the IAEA dosimetry protocols. In a previous study (Wang L L W and Rogers D W O 2008 Med. Ph...

journal_title：Physics in medicine and biology

authors： Wang LL,Rogers DW

更新日期：2009-03-21 00:00:00

abstract：:The purpose of this paper was to study the source model for a Monte Carlo simulation of electron beams from a medical linear accelerator. In a prior study, a non-divergent Gaussian source with a full-width at half-maximum (FWHM) of 0.15 cm was successful in predicting relative dose distributions for electron beams wit...

journal_title：Physics in medicine and biology

authors： Weinberg R,Antolak JA,Starkschall G,Kudchadker RJ,White RA,Hogstrom KR

更新日期：2009-01-07 00:00:00

abstract：:Techniques for reducing computation time in 3D photon dose calculations are addressed with specific emphasis given to the convolution/superposition approach. A single polyenergetic superposition model calculating absorbed dose per incident photon fluence (Gy cm2) was developed in terms of TERMA and a total energy depo...

journal_title：Physics in medicine and biology

authors： Aspradakis MM,Redpath AT

更新日期：1997-08-01 00:00:00