Abstract:
:In this paper we describe a method for quantitative photoacoustic tomography (qPAT) based on the photon radiative transfer equation (RTE) coupled with the Helmholtz photoacoustic wave equation. Considerable simulations and tissue-like phantom experiments are conducted to evaluate transport-based qPAT in comparison with diffusion-based qPAT. In these comparative simulations and experiments, we systematically examine the effects of the ratio of mu(a)/mu'(s) (absorption/reduced scattering coefficient), the anisotropy factor (g) and the imaging domain size on the transport- and diffusion-based photoacoustic image reconstruction. The results obtained show that transport-based qPAT allows for clearly more accurate recovery of the absolute absorption coefficient images of heterogeneous media over diffusion-based qPAT for all the cases examined and provides considerably improved image quality for cases where the photon diffusion approximation (DA) is invalid.
journal_name
Phys Med Bioljournal_title
Physics in medicine and biologyauthors
Yao L,Sun Y,Jiang Hdoi
10.1088/0031-9155/55/7/009subject
Has Abstractpub_date
2010-04-07 00:00:00pages
1917-34issue
7eissn
0031-9155issn
1361-6560pii
S0031-9155(10)26735-0journal_volume
55pub_type
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