Experimental determination of pCo perturbation factors for plane-parallel chambers.

abstract：:Contrast-enhanced ultrasound (US) imaging is potentially applicable to the investigation of vascular disorders of the testis. We investigated the ability of two automated computer algorithms to analyse contrast-enhanced pulse inversion US data in a rabbit model of unilateral testicular ischaemia and to correctly deter...

journal_title：Physics in medicine and biology

authors： Thierman JS,Clement GT,Kalish LA,O'Kane PL,Frauscher F,Paltiel HJ

更新日期：2006-07-21 00:00:00

abstract：:In fully three-dimensional PET imaging, iterative image reconstruction techniques usually outperform analytical algorithms in terms of image quality provided that an appropriate system model is used. In this study we concentrate on the calculation of an accurate system model for the YAP-(S)PET II small animal scanner,...

journal_title：Physics in medicine and biology

authors： Cecchetti M,Moehrs S,Belcari N,Del Guerra A

更新日期：2013-10-07 00:00:00

abstract：:Fluorescence diffuse optical tomography (fDOT) provides 3D images of fluorescence distributions in biological tissue, which represent molecular and cellular processes. The image reconstruction problem is highly ill-posed and requires regularisation techniques to stabilise and find meaningful solutions. Quadratic regul...

journal_title：Physics in medicine and biology

authors： Correia T,Koch M,Ale A,Ntziachristos V,Arridge S

更新日期：2016-02-21 00:00:00

abstract：:Previously, readings of air-filled ionization chambers have been described as being influenced by magnetic fields. To use these chambers for dosimetry in magnetic resonance guided radiotherapy (MRgRT), this effect must be taken into account by introducing a correction factor k B. The purpose of this study is to system...

journal_title：Physics in medicine and biology

authors： Pojtinger S,Dohm OS,Kapsch RP,Thorwarth D

更新日期：2018-06-07 00:00:00

abstract：:Mechanical properties of biological tissues are significant biomarkers for diagnosing various diseases. Assessing the viscoelastic properties of multi-layer tissues has remained challenging for a long time. Some shear wave models have been proposed to estimate thin-layer tissues' viscoelasticity recently. However, the...

journal_title：Physics in medicine and biology

authors： Lu G,Li R,Qian X,Chen R,Jiang L,Chen Z,Shung KK,Humayun MS,Zhou Q

更新日期：2020-11-12 00:00:00

abstract：:This study presents a combined small animal holding fixture system, termed a 'bridge capsule', which provides for small animal re-fixation with positional reproducibility. This system comprises separate holding fixtures for the head and lower body and a connecting part to a gas anesthesia system. A mouse is fixed in p...

journal_title：Physics in medicine and biology

authors： Kokuryo D,Kimura Y,Obata T,Yamaya T,Kawamura K,Zhang MR,Kanno I,Aoki I

更新日期：2010-07-21 00:00:00

abstract：:A new class of dose calibrator called a micro-dose calibrator, designed to measure radioactivity rates in the range between 1 kBq up to 370 kBq, has been designed and an 8 NaI(Tl)/photo multiplier tube (PMT) module prototype built to evaluate its performance. The design of the micro-dose calibrator is based on the con...

journal_title：Physics in medicine and biology

authors： Adler S,Choyke P

更新日期：2018-09-10 00:00:00

abstract：:A 3D anatomical computational model is developed to assess thermal effects due to exposure to the electromagnetic field required to power a new investigational active implantable microvalve for the treatment of glaucoma. Such a device, located in the temporal superior eye quadrant, produces a filtering bleb, which is ...

journal_title：Physics in medicine and biology

authors： Schaumburg F,Guarnieri FA

更新日期：2017-05-07 00:00:00

abstract：:Dual spectral computed tomography (DSCT) has a superior material distinguishability than the conventional single spectral computed tomography (SSCT). However, the decomposition process is an illposed problem, which is sensitive to noise. Thus, the decomposed image quality is degraded, and the corresponding signal-to-n...

journal_title：Physics in medicine and biology

authors： Wang Q,Zhu Y,Yu H

更新日期：2017-10-19 00:00:00

abstract：:The measurand relevant for the dosimetry for radiation therapy is the absorbed dose to water, DW. The Physikalisch-Technische Bundesanstalt (PTB) is establishing a secondary standard for DW for high-energy photon and electron radiation based on electron spin resonance (ESR) of the amino acid alanine. For practical app...

journal_title：Physics in medicine and biology

authors： Anton M

更新日期：2008-03-07 00:00:00

abstract：:In this study, two computational phantoms of the newborn patient were used to assess individual organ doses and effective doses delivered during head, chest, abdomen, pelvis, and torso examinations using the Siemens SOMATOM Sensation 16 helical multi-slice computed tomography (MSCT) scanner. The stylized phantom used ...

journal_title：Physics in medicine and biology

authors： Staton RJ,Lee C,Lee C,Williams MD,Hintenlang DE,Arreola MM,Williams JL,Bolch WE

更新日期：2006-10-21 00:00:00

abstract：:Respiratory induced resonance offset (RIRO) is a periodic disturbance of a magnetic field due to breathing. Such disturbance handicaps the accuracy of the proton resonance frequency shift (PRFS) method of MRI temperature mapping in anatomies situated nearby the lungs and chest wall. In this work, we propose a method c...

journal_title：Physics in medicine and biology

authors： Shmatukha AV,Bakker CJ

更新日期：2006-09-21 00:00:00

abstract：:New definitions of the absorbed dose conversion factors Clambda and CE are proposed. The absorbed dose in water is given by the product of absorbed dose conversion factor, exposure calibration factor, ionisation chamber reading, cap displacement correction factor and perturbation correction factor. At exposure calibra...

journal_title：Physics in medicine and biology

authors： Shiragai A

更新日期：1978-03-01 00:00:00

abstract：:Motion-adaptive radiotherapy aims to deliver a conformal dose to the target tumour with minimal normal tissue exposure by compensating for tumour motion in real time. The prediction as well as the gating of respiratory motion have received much attention over the last two decades for reducing the targeting error of th...

journal_title：Physics in medicine and biology

authors： Bukhari W,Hong SM

更新日期：2015-01-07 00:00:00

abstract：:Simultaneous near-infrared spectroscopy (NIRS) and magnetic resonance imaging (MRI) were used to investigate the correlation between tumour vascular oxygenation and tissue oxygen tension dynamics in rat breast 13762NF tumours with respect to hyperoxic gas breathing. NIRS directly detected global variations in the oxyg...

journal_title：Physics in medicine and biology

authors： Xia M,Kodibagkar V,Liu H,Mason RP

更新日期：2006-01-07 00:00:00

abstract：:Experimental radiobiological investigations of fast neutron beams involve irradiation of thin cell layers. The irradiation of cells is done either in free air or with a material such as graphite, TE plastic or bone-equivalent plastic covering the cells. This paper discusses the computed dose distributions in LET at sh...

journal_title：Physics in medicine and biology

authors： Bhatia DP,Nagarajan PS

更新日期：1979-09-01 00:00:00

abstract：:Most existing spatiotemporal multi-dipole approaches for MEG/EEG source localization assume that the dipoles are active for the full time range being analysed. If the actual time range of activity of sources is significantly shorter than the time range being analysed, the detectability, localization and time-course de...

journal_title：Physics in medicine and biology

authors： Jun SC,George JS,Plis SM,Ranken DM,Schmidt DM,Wood CC

更新日期：2006-05-21 00:00:00

abstract：:The purpose of this work was to create a computational platform for studying motion in intensity modulated radiotherapy (IMRT). Specifically, the non-uniform rational B-spline (NURB) cardiac and torso (NCAT) phantom was modified for use in a four-dimensional Monte Carlo (4D-MC) simulation system to investigate the eff...

journal_title：Physics in medicine and biology

authors： McGurk R,Seco J,Riboldi M,Wolfgang J,Segars P,Paganetti H

更新日期：2010-03-07 00:00:00

abstract：:This paper presents a new algorithm for constrained intensity-modulated radiotherapy (IMRT) planning, made tractable by a dimensionality reduction using a set of plans obtained by fast, unconstrained optimizations. The main result is to reduce planning time by an order of magnitude, producing viable five field prostat...

journal_title：Physics in medicine and biology

authors： Lu R,Radke RJ,Yang J,Happersett L,Yorke E,Jackson A

更新日期：2008-12-07 00:00:00

abstract：:Intravascular coronary thermography is a method that may detect vulnerable, atherosclerotic plaques and is currently evaluated in a clinical setting. Active macrophages or enzymatic heat releasing processes in vulnerable plaques may act as heat sources. To better understand the parameters of influence on thermographic...

journal_title：Physics in medicine and biology

authors： ten Have AG,Gijsen FJ,Wentzel JJ,Slager CJ,van der Steen AF

更新日期：2004-10-07 00:00:00

abstract：:Spectral x-ray imaging using novel photon counting x-ray detectors (PCDs) with energy resolving abilities is capable of providing energy-selective images. PCDs have energy thresholds, enabling the classification of photons into multiple energy bins. The extra energy information provided may allow materials such as iod...

journal_title：Physics in medicine and biology

authors： Nik SJ,Meyer J,Watts R

更新日期：2011-09-21 00:00:00

abstract：:Cell experiments have shown the proton relative biological effectiveness (RBE) to vary with dose and linear energy transfer (LET), which has led to development of variable RBE models. The RBE is normally estimated from two independent functions, the RBEmax and RBEmin, describing the extreme RBE at low and high doses. ...

journal_title：Physics in medicine and biology

authors： Rørvik E,Thörnqvist S,Ytre-Hauge KS

更新日期：2019-09-23 00:00:00

abstract：:Multi-material decomposition (MMD) technique decomposes the CT images into basis material images and has been promising in clinical practice for material composition quantification within the human body. MMD could be implemented using the image data acquired from spectral CT or its special case, dual-energy CT (DECT) ...

journal_title：Physics in medicine and biology

authors： Xue Y,Luo C,Jiang Y,Yang P,Hu X,Zhou Q,Wang J,Hu X,Sheng K,Niu T

更新日期：2020-03-23 00:00:00

abstract：:We find the dose distribution that maximizes the tumour control probability (TCP) for a fixed mean tumour dose per fraction. We consider a heterogeneous tumour volume having a radiation response characterized by the linear quadratic model with heterogeneous radiosensitivity and repopulation rate that may vary in time....

journal_title：Physics in medicine and biology

authors： Levin-Plotnik D,Hamilton RJ

更新日期：2004-02-07 00:00:00

abstract：:Task group 43 (TG43)-based dosimetry algorithms are efficient for brachytherapy dose calculation in water. However, human tissues have chemical compositions and densities different than water. Moreover, the mutual shielding effect of seeds on each other (interseed attenuation) is neglected in the TG43-based dosimetry ...

journal_title：Physics in medicine and biology

authors： Afsharpour H,Landry G,D'Amours M,Enger S,Reniers B,Poon E,Carrier JF,Verhaegen F,Beaulieu L

更新日期：2012-06-07 00:00:00

abstract：:The geometry of a permanent prostate implant varies over time. Seeds can migrate and edema of the prostate affects the position of seeds. Seed movements directly influence dosimetry which relates to treatment quality. We present a method that tracks all individual seeds over time allowing quantification of seed moveme...

journal_title：Physics in medicine and biology

authors： Westendorp H,Nuver TT,Moerland MA,Minken AW

更新日期：2015-10-21 00:00:00

abstract：:The purpose of this study was the evaluation of the impact of a variable relative biological effectiveness (RBE) compared to a constant RBE value of 1.1 in proton therapy prostate trials due to uncertainties in α/β ratio. Twenty patients receiving passive scattered proton therapy (PSPT) and fifteen patients receiving ...

journal_title：Physics in medicine and biology

authors： Marteinsdottir M,Paganetti H

更新日期：2019-06-05 00:00:00

abstract：:Magnetic Particle Imaging (MPI) is a promising medical imaging technique for visualizing the three-dimensional distribution of tracer materials, specifically iron oxide nanoparticles (IONP). The optimization of magnetic nanoparticles (MNP) plays an essential role to improve the image resolution and sensitivity of imag...

journal_title：Physics in medicine and biology

authors： Arsalani S,Loewa N,Kosch O,Radon P,Baffa O,Wiekhorst F

更新日期：2020-11-23 00:00:00

abstract：:This study verifies the concept of the super-omni wedge by validating its equations for effective wedge orientation and wedge angle and by comparing the dose distributions it produces with those produced by other wedge techniques. To validate the equations, we calculated dose distributions for 20 combinations of wedge...

journal_title：Physics in medicine and biology

authors： Dai J,Zhu Y,Wu X

更新日期：2001-09-01 00:00:00

abstract：:Modelling of inhaled particle deposition in the lungs potentially offers data relevant to assessing hazards from toxic inhaled particles, to studying mucus clearance or lung permeability by aerosol techniques, and to achieving better utilisation of drugs administered as aerosols. Analysis of published modelling studie...

journal_title：Physics in medicine and biology

authors： Agnew JE,Pavia D,Clarke SW

更新日期：1984-07-01 00:00:00