Analytic treatment of resolution precision in electronically collimated SPECT imaging involving multiple-interaction gamma rays.

abstract：:Large volume tissue-equivalent proportional counters are of interest in radiation protection metrology, as the sensitivity in terms of counts per unit absorbed dose in these devices increases as the square of the counter diameter. Conventional solutions to the problem of maintaining a uniform electric field within a c...

journal_title：Physics in medicine and biology

authors： Verma PK,Waker AJ

更新日期：1992-10-01 00:00:00

abstract：:A method to determine the spectrum of a clinical photon beam from measured depth-dose data is described. At shallow depths, where the range of Compton-generated electrons increases rapidly with photon energy, the depth dose provides the information to discriminate the spectral contributions. To minimize the influence ...

journal_title：Physics in medicine and biology

authors： Bloch P,Altschuler MD,Bjärngard BE,Kassaee A,McDonough J

更新日期：2000-01-01 00:00:00

abstract：:We have developed deformable and durable optical tissue phantoms with a simple and well-defined microstructure including a novel combination of scatterers and a matrix material. These were developed for speckle and elastography investigations in optical coherence tomography, but should prove useful in many other field...

journal_title：Physics in medicine and biology

authors： Bisaillon CE,Lamouche G,Maciejko R,Dufour M,Monchalin JP

更新日期：2008-07-07 00:00:00

abstract：:Diffusion tensor tractography (DTT) allows one to explore axonal connectivity patterns in neuronal tissue by linking local predominant diffusion directions determined by diffusion tensor imaging (DTI). The majority of existing tractography approaches use continuous coordinates for calculating single trajectories throu...

journal_title：Physics in medicine and biology

authors： Bodammer NC,Kaufmann J,Kanowski M,Tempelmann C

更新日期：2009-02-21 00:00:00

abstract：:The (83)Kr magnetic resonance (MR) relaxation time T(1) of krypton gas in contact with model surfaces was previously found to be highly sensitive to surface composition, surface-to-volume ratio, and surface temperature. The work presented here explored aspects of pulmonary (83)Kr T(1) relaxation measurements in excise...

journal_title：Physics in medicine and biology

authors： Stupic KF,Elkins ND,Pavlovskaya GE,Repine JE,Meersmann T

更新日期：2011-07-07 00:00:00

abstract：:The measurement of output factors (OF) for the small photon beams generated by Leksell Gamma Knife® (LGK) radiotherapy units is a challenge for the physicist due to the under or over estimation of these factors by a vast majority of the detectors commercially available. Output correction factors, introduced in the int...

journal_title：Physics in medicine and biology

authors： Benmakhlouf H,Johansson J,Paddick I,Andreo P

更新日期：2015-05-21 00:00:00

abstract：:For PET online data acquisition, a centralized coincidence processor (CCP) with a single-thread data processing has been used to select coincidence events for many PET scanners. CCP has the advantage of highly integrated circuit, compact connection between detector front-end and system electronics, and centralized con...

journal_title：Physics in medicine and biology

authors： Cheng X,Hu K,Yang D,Shao Y

更新日期：2021-01-21 00:00:00

abstract：:A correction for loss of events due to dead time in dynamic positron emission tomography (PET) is presented. The model employs a paralysing dead time to describe the behaviour of a tomograph over the range of event rates normally encountered in patient studies (up to 200 000 events/s per detector layer). The Donner 28...

journal_title：Physics in medicine and biology

authors： Mazoyer BM,Roos MS,Huesman RH

更新日期：1985-05-01 00:00:00

abstract：:When dosimetric effects in time-dependent geometries are studied, usually either the results of individual three-dimensional (3D) calculations are combined or probability-based approaches are applied. These methods may become cumbersome and time-consuming if high time resolution is required or if the geometry is compl...

journal_title：Physics in medicine and biology

authors： Paganetti H,Jiang H,Trofimov A

更新日期：2005-03-07 00:00:00

abstract：:We report a simulation study on diffuse reflective optical computed tomography, in which continuous-wave sources and detectors are placed on the plane surface of a semi-infinite body. We adopted a simple Tikhonov regularization in the inverse problem and demonstrated the feasibility of three-dimensional reconstruction...

journal_title：Physics in medicine and biology

authors： Endoh R,Suzuki A,Fujii M,Nakayama K

更新日期：2004-05-21 00:00:00

abstract：:The treatment delivery time of intensity-modulated radiation therapy (IMRT) with a multileaf collimator (MLC) is generally longer than that of conventional radiotherapy. In theory, removing the flattening filter from the treatment head may reduce the beam-on time by enhancing the output dose rate, and then reduce the ...

journal_title：Physics in medicine and biology

authors： Fu W,Dai J,Hu Y,Han D,Song Y

更新日期：2004-04-21 00:00:00

abstract：:In the current work, EPR (electron paramagnetic resonance) dosimetry using alanine films (134 microm thick) was utilized for dose measurements in inhomogeneous phantoms irradiated with radiotherapy photon beams. The main phantom material was PMMA, while either Styrofoam or aluminium was introduced as an inhomogeneity....

journal_title：Physics in medicine and biology

authors： Osterås BH,Hole EO,Olsen DR,Malinen E

更新日期：2006-12-21 00:00:00

abstract：:Conversion factors, which relate the kerma-area product to effective dose, have been estimated for paediatric cardiac x-ray angiography. Monte Carlo techniques have been used to calculate the conversion factors for a wide range of projection angles for children of five ages and for adults. Correction factors are provi...

journal_title：Physics in medicine and biology

authors： Schmidt PW,Dance DR,Skinner CL,Smith IA,McNeill JG

更新日期：2000-10-01 00:00:00

abstract：:Periacetabular osteotomy (PAO) is a joint preservation procedure for developmental dysplasia of the hip. Such a procedure requires osteotomy of the medial wall of the acetabulum, which may cause the narrow of the bony birth canal and increase the risk of complications during the childbirth process in the future. Using...

journal_title：Physics in medicine and biology

authors： Shao L,Li H,Liu X,Wang Y,Shi L,Ai D,Fan J,Song H,Zhang H,Yang J

更新日期：2021-01-22 00:00:00

abstract：:The purpose of this work is to develop a validated Geant4 simulation model of a whole-body prototype PET scanner constructed from the four-layer depth-of-interaction detectors developed at the National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Japan. T...

journal_title：Physics in medicine and biology

authors： Ahmed AM,Chacon A,Rutherford H,Akamatsu G,Mohammadi A,Nishikido F,Tashima H,Yoshida E,Yamaya T,Franklin DR,Rosenfeld A,Guatelli S,Safavi-Naeini M

更新日期：2020-12-18 00:00:00

abstract：:Intensity-modulated radiation therapy (IMRT) can be delivered by the 'sliding-leaves' dynamic multileaf collimator (DMLC) technique. Intrafraction organ motion can be accommodated by arranging an identical tracking motion for 'breathing leaves'. However, this is only possible for very specific circumstances such as re...

journal_title：Physics in medicine and biology

authors： Webb S,Binnie DM

更新日期：2006-09-21 00:00:00

abstract：:The aim of the study is to verify the fundamental assumption in the monitor source method, i.e. uniform fractional count loss across the field of view (FOV), and to introduce a revised monitor source method for SPECT deadtime correction that minimally interferes with the clinical protocol. SPECT images of non-uniform ...

journal_title：Physics in medicine and biology

authors： Siman W,Silosky M,Kappadath SC

更新日期：2015-02-07 00:00:00

abstract：:As a part of an ongoing effort to develop computerized planning tools for cryosurgery, an experimental study has been conducted to verify a recently developed numerical technique for bioheat transfer simulations. Experiments were performed on gelatin solution as a phantom material, using proprietary liquid-nitrogen cr...

journal_title：Physics in medicine and biology

authors： Rossi MR,Rabin Y

更新日期：2007-08-07 00:00:00

abstract：:The medical imaging and therapeutic technologies that are based on the use of radiation are reviewed briefly, with special emphasis on the recent developments of synchrotron radiation (SR) methods. New results have been achieved in all of these areas since the last comprehensive reviews were written in this field. Thi...

journal_title：Physics in medicine and biology

authors： Suortti P,Thomlinson W

更新日期：2003-07-07 00:00:00

abstract：:An accurate, low noise estimate of photon attenuation in the subject is required for quantitative microPET studies of molecular tracer distributions in vivo. In this work, several transmission-based measurement techniques were compared, including coincidence mode with and without rod windowing, singles mode with two d...

journal_title：Physics in medicine and biology

authors： Lehnert W,Meikle SR,Siegel S,Newport D,Banati RB,Rosenfeld AB

更新日期：2006-08-21 00:00:00

abstract：:We developed an anatomy-guided 4D closed-form algorithm to directly reconstruct parametric images from projection data for (nearly) irreversible tracers. Conventional methods consist of individually reconstructing 2D/3D PET data, followed by graphical analysis on the sequence of reconstructed image frames. The propose...

journal_title：Physics in medicine and biology

authors： Tang J,Kuwabara H,Wong DF,Rahmim A

更新日期：2010-08-07 00:00:00

abstract：:A hybrid proportional-integral-in-time and cost-minimizing-in-space feedback control system for electromagnetic, deep regional hyperthermia is proposed. The unique features of this controller are that (1) it uses temperature, not specific absorption rate, as the criterion for selecting the relative phases and amplitud...

journal_title：Physics in medicine and biology

authors： Kowalski ME,Jin JM

更新日期：2003-03-07 00:00:00

abstract：:A novel radiation targeted therapy is investigated for HER-2 positive breast cancers. The proposed concept combines two known approaches, but never used together for the treatment of advanced, relapsed or metastasized HER-2 positive breast cancers. The proposed radiation binary targeted concept is based on the anti HE...

journal_title：Physics in medicine and biology

authors： Mundy DW,Harb W,Jevremovic T

更新日期：2006-03-21 00:00:00

abstract：:Doxorubicin (Dox) is a well-established chemotherapeutic agent, however it has limited efficacy in treating brain malignancies due to the presence of the blood-brain barrier (BBB). Recent preclinical studies have demonstrated that focused ultrasound induced BBB disruption (BBBD) enables efficient delivery of Dox to th...

journal_title：Physics in medicine and biology

authors： Nhan T,Burgess A,Lilge L,Hynynen K

更新日期：2014-10-21 00:00:00

abstract：:The dosimetric impact of intrafraction prostate motion was investigated for helical tomotherapy treatments. Measured motion tracks were used to calculate the dosimetric impact on delivered target dose distributions. A dynamic dose calculation engine was developed to facilitate this evaluation. It was found that the D9...

journal_title：Physics in medicine and biology

authors： Langen KM,Lu W,Ngwa W,Willoughby TR,Chauhan B,Meeks SL,Kupelian PA,Olivera G

更新日期：2008-12-21 00:00:00

abstract：:Although field area and object thickness are important parameters in comparisons of techniques for optimal reduction of scattered radiation to the image, they are in practice seldom varied. For this reason, we suggest that contrast degradation (CDF) and contrast improvement (CIF) factors be more frequently used and ap...

journal_title：Physics in medicine and biology

authors： Carlsson GA,Carlsson CA,Nielsen B,Persliden J

更新日期：1986-07-01 00:00:00

abstract：:Three-dimensional reconstruction of coronary arteries can be performed during x-ray-guided interventions by gated reconstruction from a rotational coronary angiography sequence. Due to imperfect gating and cardiac or breathing motion, the heart's motion state might not be the same in all projections used for the recon...

journal_title：Physics in medicine and biology

authors： Hansis E,Schäfer D,Dössel O,Grass M

更新日期：2008-07-21 00:00:00

abstract：:This work investigates the attenuation of a proton beam to reconstruct the map of the linear attenuation coefficient of a material which is mainly caused by the inelastic interactions of protons with matter. Attenuation proton computed tomography (pCT) suffers from a poor spatial resolution due to multiple Coulomb sca...

journal_title：Physics in medicine and biology

authors： Quiñones CT,Létang JM,Rit S

更新日期：2016-05-07 00:00:00

abstract：:It seems likely that long term patency of small bore vascular prostheses is dependent upon, among other things, the mechanical properties of their walls. Arteries are visco-elastic but there is no accurate method of measuring the visco-elasticity of arterial substitutes in vivo. The most successful vascular substitute...

journal_title：Physics in medicine and biology

authors： Chapman BL,Charlesworth D

更新日期：1983-09-01 00:00:00

abstract：:Brain stereotactic radiosurgery (SRS) treatments require multiple quality assurance (QA) procedures to ensure accurate and precise treatment delivery. As single-isocenter multitarget SRS treatments become more popular, the quantification of off-axis accuracy of the linear accelerator is crucial. In this study, a novel...

journal_title：Physics in medicine and biology

authors： Capaldi DPI,Skinner LB,Dubrowski P,Yu AS

更新日期：2020-06-10 00:00:00