Projection-based motion compensation for gated coronary artery reconstruction from rotational x-ray angiograms.

abstract：:In response to the recognized fragility of reactor-produced (99)Mo supply, direct production of (99m)Tc via (100)Mo(p,2n)(99m)Tc reaction using medical cyclotrons has been investigated. However, due to the existence of other Molybdenum (Mo) isotopes in the target, in parallel with (99m)Tc, other technetium (Tc) radioa...

journal_title：Physics in medicine and biology

authors： Hou X,Tanguay J,Buckley K,Schaffer P,Bénard F,Ruth TJ,Celler A

更新日期：2016-01-21 00:00:00

abstract：:We report on a novel method for simultaneous biological optimization of treatment plans for hypoxic tumors using multiple ion species. Our previously introduced kill painting approach, where the overall cell killing is optimized on biologically heterogeneous targets, was expanded with the capability of handling differ...

journal_title：Physics in medicine and biology

authors： Sokol O,Krämer M,Hild S,Durante M,Scifoni E

更新日期：2019-02-08 00:00:00

abstract：:We propose a hybrid multiobjective (MO) evolutionary optimization algorithm (MOEA) for intensity-modulated radiotherapy inverse planning and apply it to optimize the number of incident beams, their orientations and intensity profiles. The algorithm produces a set of efficient solutions, which represent different clini...

journal_title：Physics in medicine and biology

authors： Schreibmann E,Lahanas M,Xing L,Baltas D

更新日期：2004-03-07 00:00:00

abstract：:The peak CT number (CT) and full width at half maximum (FWHM) were obtained from the image profiles of aluminium of thickness ranging from 0.1-9.5 mm. The scans were performed at different fields of view (FOVs) and with different reconstruction algorithms ('bone' and 'standard'). Above 3 mm, CT and FWHM provide measur...

journal_title：Physics in medicine and biology

authors： Newman DL,Dougherty G,al Obaid A,al Hajrasy H

更新日期：1998-03-01 00:00:00

abstract：:In radiotherapy with photon beams, the use of dynamic wedges, which are obtained by the movement of one of the jaws, offers an increasing flexibility relative to the traditional use of metal wedges. But it is a disadvantage for the measurement of absorbed dose distributions, because the absorbed dose at each measureme...

journal_title：Physics in medicine and biology

authors： Storchi P,Woudstra E,Verlinde P,Johansson KA,Samuelsson A

更新日期：1998-06-01 00:00:00

abstract：:This study presents a new approach to accurately account for the medium-dependent effect in model-based dose calculations for kilovoltage (kV) x-rays. This approach is based on the hypothesis that the correction factors needed to convert dose from model-based dose calculations to absorbed dose-to-medium depend on both...

journal_title：Physics in medicine and biology

authors： Pawlowski JM,Ding GX

更新日期：2011-07-07 00:00:00

abstract：:For quality assurance of hyperthermia treatment planning systems, quantitative validation of the electromagnetic model of an applicator is essential. The objective of this study was to validate a finite-difference time-domain (FDTD) model implementation of the Lucite cone applicator (LCA) for superficial hyperthermia....

journal_title：Physics in medicine and biology

authors： de Bruijne M,Samaras T,Chavannes N,van Rhoon GC

更新日期：2007-06-07 00:00:00

abstract：:In this work we present a new 3D numerical model for heat transfer in the human eye, which takes into account the aqueous humour flow in the anterior chamber. We show that consideration of this phenomenon in the calculations alters the temperature distribution on the corneal and lens surfaces, without, however, notice...

journal_title：Physics in medicine and biology

authors： Karampatzakis A,Samaras T

更新日期：2010-10-07 00:00:00

abstract：:Ultrasonic speed of propagation and attenuation were investigated as a function of absorbed radiation dose in PAG and MAGIC polymer gel dosimeters. Both PAG and MAGIC gel dosimeters displayed a dependence of ultrasonic parameters on absorbed dose with attenuation displaying significant changes in the dose range invest...

journal_title：Physics in medicine and biology

authors： Mather ML,De Deene Y,Whittaker AK,Simon GP,Rutgers R,Baldock C

更新日期：2002-12-21 00:00:00

abstract：:Radiotherapy calculations often involve complex geometries such as interfaces between materials of vastly differing atomic number, such as lung, bone and/or air interfaces. Monte Carlo methods have been used to calculate accurately the perturbation effects of the interfaces. However, these methods can be computational...

journal_title：Physics in medicine and biology

authors： Gifford KA,Horton JL,Wareing TA,Failla G,Mourtada F

更新日期：2006-05-07 00:00:00

abstract：:Ho-166 is a combined beta-gamma emitter of which the betas can be used therapeutically. From the 81 keV gammas of Ho-166, SPECT images can be obtained, which give opportunities to guide Ho-166 therapy. Accurate reconstruction of Ho-166 images is currently hampered by photopeak-scatter in the patient, down-scatter in t...

journal_title：Physics in medicine and biology

authors： de Wit TC,Xiao J,Nijsen JF,van het Schip FD,Staelens SG,van Rijk PP,Beekman FJ

更新日期：2006-10-07 00:00:00

abstract：:A method to measure the detector-to-object distance from the images obtained with stationary high-spatial-resolution gamma-ray cameras for in vivo studies has been developed. It exploits the shift of the imaged object in the image plane, obtained at a certain tilt of the parallel-hole collimator. A linear dependence o...

journal_title：Physics in medicine and biology

authors： Uzunov N,Bello M,Boccaccio P,Moschini G,Bollini D,de Notaristefani F

更新日期：2006-05-07 00:00:00

abstract：:An overview of the theory of 4D image reconstruction for emission tomography is given along with a review of the current state of the art, covering both positron emission tomography and single photon emission computed tomography (SPECT). By viewing 4D image reconstruction as a matter of either linear or non-linear par...

journal_title：Physics in medicine and biology

authors： Reader AJ,Verhaeghe J

更新日期：2014-11-21 00:00:00

abstract：:To predict the temperature distribution during hyperthermia treatments a thermal model that accounts for the thermal effect of blood flow is mandatory. The DIscrete VAsculature (DIVA) thermal model developed at our department is able to do so; geometrically described vessels are handled individually and the remaining ...

journal_title：Physics in medicine and biology

authors： Raaymakers BW,Crezee J,Lagendijk JJ

更新日期：2000-03-01 00:00:00

abstract：:A novel radiation targeted therapy is investigated for HER-2 positive breast cancers. The proposed concept combines two known approaches, but never used together for the treatment of advanced, relapsed or metastasized HER-2 positive breast cancers. The proposed radiation binary targeted concept is based on the anti HE...

journal_title：Physics in medicine and biology

authors： Mundy DW,Harb W,Jevremovic T

更新日期：2006-03-21 00:00:00

abstract：:The variety of treatment options for cancer patients has increased significantly in recent years. Not only do we combine radiation with surgery and chemotherapy, new therapeutic approaches such as immunotherapy and targeted therapies are starting to play a bigger role. Physics has made significant contributions to rad...

journal_title：Physics in medicine and biology

authors： Grassberger C,Paganetti H

更新日期：2016-11-07 00:00:00

abstract：:The reference levels and maximum permissible exposure values for magnetic fields that are currently used have been derived from basic restrictions under the assumption of upright standing body models in a standard posture, i.e. with arms laterally down and without contact with metallic objects. Moreover, if anatomical...

journal_title：Physics in medicine and biology

authors： Schmid G,Hirtl R

更新日期：2016-06-21 00:00:00

abstract：:The relative biological effectiveness (RBE) of protons varies with multiple physical and biological factors. Phenomenological RBE models have been developed to include such factors in the estimation of a variable RBE, in contrast to the clinically applied constant RBE of 1.1. In this study, eleven published phenomenol...

journal_title：Physics in medicine and biology

authors： Rørvik E,Fjæra LF,Dahle TJ,Dale JE,Engeseth GM,Stokkevåg CH,Thörnqvist S,Ytre-Hauge KS

更新日期：2018-09-13 00:00:00

abstract：:Monolithic scintillation detectors for positron emission tomography and single-photon emission computed tomography (SPECT) imaging have many advantages over pixelated detectors. The use of monolithic crystals allows for reducing the scintillator cost per unit volume and increasing the sensitivity along with the energy...

journal_title：Physics in medicine and biology

authors： España S,Deprez K,Van Holen R,Vandenberghe S

更新日期：2013-07-21 00:00:00

abstract：:The use of deformable image registration methods in the context of adaptive radiotherapy leads to uncertainties in the simulation of the administered dose distributions during the treatment course. Evaluation of these methods is a prerequisite to decide if a plan adaptation will improve the individual treatment. Curre...

journal_title：Physics in medicine and biology

authors： Teske H,Bartelheimer K,Meis J,Bendl R,Stoiber EM,Giske K

更新日期：2017-06-21 00:00:00

abstract：:Near-infrared fluorescence optical imaging has the unique opportunity of differentiating diseased lesions from normal lesions based upon environmentally indicated changes in the lifetime of a fluorescent imaging agent. In this paper, we demonstrate three-dimensional lifetime tomography using the gradient-based penalty...

journal_title：Physics in medicine and biology

authors： Roy R,Godavarty A,Sevick-Muraca EM

更新日期：2007-07-21 00:00:00

abstract：:In clinical computed tomography (CT) images, cortical bone features with sub-millimeter (sub-mm) thickness are substantially blurred, such that their thickness is overestimated and their intensity appears underestimated. Therefore, any inquiry of the geometry or the density of such bones based on these images is sever...

journal_title：Physics in medicine and biology

authors： Pakdel A,Robert N,Fialkov J,Maloul A,Whyne C

更新日期：2012-12-07 00:00:00

abstract：:Image-guided radiation therapy using implanted fiducial markers is a common solution for prostate localization to improve targeting accuracy. However, fiducials that are typically used for conventional photon radiotherapy cause large dose perturbations in patients who receive proton radiotherapy. A proposed solution h...

journal_title：Physics in medicine and biology

authors： Cheung J,Kudchadker RJ,Zhu XR,Lee AK,Newhauser WD

更新日期：2010-12-07 00:00:00

abstract：:We evaluated the basic properties of a commercially available BANGkit gel dosimeter, which is a normoxic type of BANG gel. This gel-kit has the same composition as the BANG 3 gel, but is fully oxygenated. To exclude oxygen, oxygen scavenging ascorbic acid and copper sulfate as a catalyst are used. The properties that ...

journal_title：Physics in medicine and biology

authors： Murakami Y,Nakashima T,Watanabe Y,Akimitsu T,Matsuura K,Kenjo M,Kaneyasu Y,Wadasaki K,Hirokawa Y,Ito K

更新日期：2007-04-21 00:00:00

abstract：:It has been reported that the dose effects of metallic guidewires are significant in intravascular brachytherapy (IVBT) using a beta source. The purpose of this work is to investigate the dependence of these dose effects on guidewire position. The EGS4 Monte Carlo codes were used to perform the dose calculations for t...

journal_title：Physics in medicine and biology

authors： Shih R,Hsu WL,Li XA

更新日期：2002-05-21 00:00:00

abstract：:The x-ray exposure to patients has become a major concern in computed tomography (CT) and minimizing the radiation exposure has been one of the major efforts in the CT field. Due to plenty high-attenuation tissues in the human chest, under low-dose scan protocols, thoracic low-dose CT (LDCT) images tend to be severely...

journal_title：Physics in medicine and biology

authors： Chen Y,Yang Z,Hu Y,Yang G,Zhu Y,Li Y,Luo L,Chen W,Toumoulin C

更新日期：2012-05-07 00:00:00

abstract：:Heterogeneity corrections for radiotherapy dose calculations are based on the electron density of the disturbing heterogeneity. However, when CT planning a radiotherapy treatment, where metallic hip implants are present, considerable artefacts are seen in the images. Often, an additional problem arises whereby no info...

journal_title：Physics in medicine and biology

authors： Coolens C,Childs PJ

更新日期：2003-06-07 00:00:00

abstract：:The measured attenuation correction technique is widely used in cardiac positron tomographic studies. However, the success of this technique is limited because of insufficient counting statistics achievable in practical transmission scan times, and of the scattered radiation in transmission measurement which leads to ...

journal_title：Physics in medicine and biology

authors： Yu SK,Nahmias C

更新日期：1996-10-01 00:00:00

abstract：:The aim of this study was to evaluate angiogenic compositions and tumour response in the course of neoadjuvant chemotherapy in patients with locally advanced breast cancer (LABC) using dynamic contrast-enhanced (DCE) MRI. Thirteen patients with LABC underwent serial DCE MRI during the course of chemotherapy. DCE MRI w...

journal_title：Physics in medicine and biology

authors： Chang YC,Huang CS,Liu YJ,Chen JH,Lu YS,Tseng WY

更新日期：2004-08-21 00:00:00

abstract：:Medulloblastoma treatment involves irradiation of the entire central nervous system, i.e. craniospinal irradiation (CSI). This is associated with the significant exposure of large volumes of healthy tissue and there is growing concern regarding treatment-associated side effects. The current study compares out-of-field...

journal_title：Physics in medicine and biology

authors： De Saint-Hubert M,Verellen D,Poels K,Crijns W,Magliona F,Depuydt T,Vanhavere F,Struelens L

更新日期：2017-07-07 00:00:00