Multiobjective evolutionary optimization of the number of beams, their orientations and weights for intensity-modulated radiation therapy.

abstract：:In magnetic resonance (MR) guided radiotherapy, the magnetic field-dependent change in the dose response of ionization chambers is typically included by means of a correction factor [Formula: see text]. This factor can be determined experimentally or calculated by means of Monte Carlo (MC) simulations. To date, a smal...

journal_title：Physics in medicine and biology

authors： Pojtinger S,Kapsch RP,Dohm OS,Thorwarth D

更新日期：2019-07-04 00:00:00

abstract：:Despite the early recognition of the potential of proton imaging to assist proton therapy (Cormack 1963 J. Appl. Phys. 34 2722), the modality is still removed from clinical practice, with various approaches in development. For proton-counting radiography applications such as computed tomography (CT), the water-equival...

journal_title：Physics in medicine and biology

authors： Poludniowski G,Allinson NM,Anaxagoras T,Esposito M,Green S,Manolopoulos S,Nieto-Camero J,Parker DJ,Price T,Evans PM

更新日期：2014-06-07 00:00:00

abstract：:In interstitial heating one of the main requirements for achieving a certain elevated temperature in a tumour is that the effective power per applicator (Peff), i.e. the power which is actually deposited in the tissue, is sufficiently high. In this paper this requirement is discussed for the applicators of the 27 MHz ...

journal_title：Physics in medicine and biology

authors： Kaatee RS,Crezee J,Kanis AP,Lagendijk JJ,Levendag PC,Visser AG

更新日期：1997-06-01 00:00:00

abstract：:A method for the calculation of absorbed dose distributions of arbitrarily shaped electron beams is presented. Isodose distributions and output factors of treatment fields can be predicted with good accuracy, without the need for any dose measurement in the actual field. A Gaussian pencil beam model is employed with t...

journal_title：Physics in medicine and biology

authors： Bruinvis IA,Van Amstel A,Elevelt AJ,Van der Laarse R

更新日期：1983-06-01 00:00:00

abstract：:Statistically based iterative image reconstruction methods have been developed for emission tomography. One important component in iterative image reconstruction is the system matrix, which defines the mapping from the image space to the data space. Several groups have demonstrated that an accurate system matrix can i...

journal_title：Physics in medicine and biology

authors： Qi J,Huesman RH

更新日期：2005-07-21 00:00:00

abstract：:Radiotherapy treatment planning is associated with uncertainties. Examples are uncertainties in the tumour location due to organ movement or the inter/intra observer variability in target definition. Different approaches to incorporate uncertainties into IMRT optimization have been proposed. In this note, we point out...

journal_title：Physics in medicine and biology

authors： Unkelbach J,Oelfke U

更新日期：2006-12-07 00:00:00

abstract：:The dielectric properties of glycerol, propylene glycol, ethylene glycol and dimethyl sulphoxide have been measured in various aqueous concentrations generally sufficient to allow supercooling rather than freezing. The temperature range investigated is from -80 degrees C to +20 degrees C and the frequency range is 100...

journal_title：Physics in medicine and biology

authors： Michelson SC,Evans S

更新日期：1996-10-01 00:00:00

abstract：:A three-dimensional (3D) point-kernel multiple scatter model for point spread function (PSF) determination in parallel-beam single-photon emission computed tomography (SPECT), based on a dose gamma-ray buildup factor, is proposed. This model embraces nonuniform attenuation in a voxelized object of imaging (patient bod...

journal_title：Physics in medicine and biology

authors： Marinkovic P,Ilic R,Spaic R

更新日期：2007-10-07 00:00:00

abstract：:This study investigated the integration of the Calypso real-time tracking system, based on implanted ferromagnetic transponders and a detector array, into the current process for image-guided radiation treatment (IGRT) of prostate cancer at our institution. The current IGRT process includes magnetic resonance imaging ...

journal_title：Physics in medicine and biology

authors： Zhu X,Bourland JD,Yuan Y,Zhuang T,O'Daniel J,Thongphiew D,Wu QJ,Das SK,Yoo S,Yin FF

更新日期：2009-09-07 00:00:00

abstract：:A technique is described for examining the mode of operation of radiation detectors and estimating the losses and gains caused by random summing effects in spectra acquired at high counting rates. The technique is applied to estimating the errors caused by random summing when measuring the amounts of carbon and nitrog...

journal_title：Physics in medicine and biology

authors： Yankuba S,Oldroyd B,Metcalfe SC,Godfrey JE,Oxby CB

更新日期：1989-08-01 00:00:00

abstract：:Accurate scatter correction is required to produce high-quality reconstructions of x-ray cone-beam computed tomography (CBCT) scans. This paper describes new scatter kernel superposition (SKS) algorithms for deconvolving scatter from projection data. The algorithms are designed to improve upon the conventional approac...

journal_title：Physics in medicine and biology

authors： Sun M,Star-Lack JM

更新日期：2010-11-21 00:00:00

abstract：:We propose a retrospective respiratory gating algorithm to generate dynamic CT studies. To this end, we compared three different methods of extracting the respiratory signal from the projections of small-animal cone-beam computed tomography (CBCT) scanners. Given a set of frames acquired from a certain axial angle, su...

journal_title：Physics in medicine and biology

authors： Chavarrías C,Vaquero JJ,Sisniega A,Rodríguez-Ruano A,Soto-Montenegro ML,García-Barreno P,Desco M

更新日期：2008-09-07 00:00:00

abstract：:As an x-ray beam goes through the human body, it will collect important information via interaction with tissues. Since this interaction is energy-sensitive, the state-of-the-art spectral CT technologies provide higher quality images of biological tissues with x-ray energy information (or spectral information). With e...

journal_title：Physics in medicine and biology

authors： Shi Z,Yang H,Cong W,Wang G

更新日期：2016-06-07 00:00:00

abstract：:Fully three-dimensional positron emission tomography is considered and a reconstruction algorithm derived. The reconstruction problem is formulated mathematically as a three-dimensional convolution integral of a point spread function with an unknown positron activity distribution and is solved by Fourier transform met...

journal_title：Physics in medicine and biology

authors： Colsher JG

更新日期：1980-01-01 00:00:00

abstract：:This paper introduces a method to simultaneously minimize the leaf travel distance and the tongue-and-groove effect for IMRT leaf sequences to be delivered in segmental mode. The basic idea is to add a large enough number of openings through cutting or splitting existing openings for those leaf pairs with openings few...

journal_title：Physics in medicine and biology

authors： Dai J,Que W

更新日期：2004-12-07 00:00:00

abstract：:The purpose of this study is to calculate Pareto surfaces in multi-criteria radiation treatment planning and to analyse the dependency of the Pareto surfaces on the objective functions used for the volumes of interest. We develop a linear approach that allows us to calculate truly Pareto optimal treatment plans, and w...

journal_title：Physics in medicine and biology

authors： Craft D,Halabi T,Bortfeld T

更新日期：2005-12-21 00:00:00

abstract：:This study aims at investigating in real-time the structural and dynamical changes occurring in an ex vivo tissue during a microwave thermal ablation (MTA) procedure. The experimental set-up was based on ex vivo liver tissue inserted in a dedicated box, in which 3 fibre-optic (FO) temperature probes were introduced to...

journal_title：Physics in medicine and biology

authors： Strigari L,Minosse S,D'Alessio D,Farina L,Cavagnaro M,Cassano B,Pinto R,Vallati G,Lopresto V

更新日期：2019-05-31 00:00:00

abstract：:Existing studies have suggested some debate on whether the quality of radiation that delivers dose outside of the primary field of a radiotherapy photon beam can be considered the same as that inside the primary field. We used a Monte Carlo approach to simulate the electron fluence differential in energy inside a wate...

journal_title：Physics in medicine and biology

authors： Kirkby C,Field C,MacKenzie M,Syme A,Fallone BG

更新日期：2007-06-21 00:00:00

abstract：:The delivery of volumetric modulated arc therapy (VMAT) requires the simultaneous movement of the linear accelerator gantry, multi-leaf collimators and jaws while the dose rate is varied. In this study, a VMAT delivery emulator was developed to accurately predict the characteristics of a given treatment plan, incorpor...

journal_title：Physics in medicine and biology

authors： Boylan CJ,Rowbottom CG,Mackay RI

更新日期：2011-07-07 00:00:00

abstract：:Lung 4D computed tomography (4D-CT), which is a time-resolved CT data acquisition, performs an important role in explicitly including respiratory motion in treatment planning and delivery. However, the radiation dose is usually reduced at the expense of inter-slice spatial resolution to minimize radiation-related heal...

journal_title：Physics in medicine and biology

authors： Fang S,Wang H,Liu Y,Zhang M,Yang W,Feng Q,Chen W,Zhang Y

更新日期：2017-10-03 00:00:00

abstract：:The energy dependence of the luminance ratio due to scattered and primary radiation has been determined for four types of X-ray intensifying screens. A water phantom of 30 cm X 30 cm X 20 cm was used as the scattering medium. Ten narrow band X-ray spectra were used as incident radiation: the mean energies of these spe...

journal_title：Physics in medicine and biology

authors： Koedooder K,Venema HW

更新日期：1984-10-01 00:00:00

abstract：:Time-of-flight (TOF) positron emission tomography (PET) technology has recently regained popularity in clinical PET studies for improving image quality and lesion detectability. Using TOF information, the spatial location of annihilation events is confined to a number of image voxels along each line of response, there...

journal_title：Physics in medicine and biology

authors： Mehranian A,Kotasidis F,Zaidi H

更新日期：2016-02-07 00:00:00

abstract：:Although x-ray mammography is widely developed for breast tumour detection, it suffers from spatial superposition in its two-dimensional (2D) representation of a three-dimensional (3D) breast structure. Accordingly, 3D breast imaging, such as cone-beam computed tomography (CT), arises at the historic moment. In this p...

journal_title：Physics in medicine and biology

authors： Chen Z,Ning R

更新日期：2003-07-21 00:00:00

abstract：:Fixed-pattern noise in electronic portal images (EPIs) is normally eliminated by dividing raw image data by an open-field calibration image (OFCI). However, for successful elimination, there must be exact registration between the two image sets. Any movement within the imaging system, such as that which occurs with ga...

journal_title：Physics in medicine and biology

authors： Kirby MC

更新日期：1996-11-01 00:00:00

abstract：:We study the spatial distributions of beta(+)-activity produced by therapeutic beams of (3)He and (12)C ions in various tissue-like materials. The calculations were performed within a Monte Carlo model for heavy-ion therapy (MCHIT) based on the GEANT4 toolkit. The contributions from positron-emitting nuclei with T(1/2...

journal_title：Physics in medicine and biology

authors： Pshenichnov I,Larionov A,Mishustin I,Greiner W

更新日期：2007-12-21 00:00:00

abstract：:The objective in cancer radiotherapy is to maximize tumor-kill while limiting toxic effects of radiation dose on nearby organs-at-risk (OAR). Given a fixed number of treatment sessions, planners thus face the problem of finding a dosing sequence that achieves this goal. This is called the fractionation problem, and ha...

journal_title：Physics in medicine and biology

authors： Ghate A

更新日期：2020-09-16 00:00:00

abstract：:Several types of intravascular ultrasound (IVUS) catheters are connected to a motor at their proximal end, in order to let the catheter rotate around its length axis. However, the rotation of the distal axis tip does not follow exactly the rotation of the motor, since the catheter axis is not completely torsion-free a...

journal_title：Physics in medicine and biology

authors： Konings MK,van Leeuwen TG,Mali WP,Viergever MA

更新日期：1998-05-01 00:00:00

abstract：:Within an epidemiological study regarding the correlation between skin pathologies and personal ultraviolet (UV) exposure due to solar radiation, 14 field campaigns using polysulphone (PS) dosemeters were carried out at three different Italian sites (urban, semi-rural and rural) in every season of the year. A polysulp...

journal_title：Physics in medicine and biology

authors： Casale GR,Borra M,Colosimo A,Colucci M,Militello A,Siani AM,Sisto R

更新日期：2006-09-07 00:00:00

abstract：:The aim of this study is to investigate the use of mathematical morphology for the determination of left ventricular contours in scintigraphic images using multigated radionuclide angiography. We have developed a completely automatic method that first restores the image with a Wiener filter, then finds the region wher...

journal_title：Physics in medicine and biology

authors： Pladellorens J,Serrat J,Castell A,Yzuel MJ

更新日期：1993-12-01 00:00:00

abstract：:In order to analyse the respective roles of ion concentration and fractional volume of the interstitial compartment as determinants of the impedance, Z, of renal medullary tissue, a model was needed in which both these factors could be varied independently. An array of blood cell suspensions ions in saline (different ...

journal_title：Physics in medicine and biology

authors： Niewiadomski W,Sadowski J,Badzyńska B,Rasmussen SN

更新日期：1990-11-01 00:00:00