Exploration of tradeoffs in intensity-modulated radiotherapy.

abstract：:A calibration of the Fricke dosimeter is a measurement of epsilon G(Fe3+). Although G(Fe3+) is expected to be approximately energy independent for all low-LET radiation, existing data are not adequate to rule out the possibility of changes of a few per cent with beam quality. When a high-precision Fricke dosimeter, wh...

journal_title：Physics in medicine and biology

authors： Klassen NV,Shortt KR,Seuntjens J,Ross CK

更新日期：1999-07-01 00:00:00

abstract：:We present a method to include robustness in a multi-criteria optimization (MCO) framework for intensity-modulated proton therapy (IMPT). The approach allows one to simultaneously explore the trade-off between different objectives as well as the trade-off between robustness and nominal plan quality. In MCO, a database...

journal_title：Physics in medicine and biology

authors： Chen W,Unkelbach J,Trofimov A,Madden T,Kooy H,Bortfeld T,Craft D

更新日期：2012-02-07 00:00:00

abstract：:The purpose of this paper for four-dimensional (4D) computed tomography (CT) is threefold. (1) A new spatiotemporal model is presented from the matrix perspective with the row dimension in space and the column dimension in time, namely the robust PCA (principal component analysis)-based 4D CT model. That is, instead o...

journal_title：Physics in medicine and biology

authors： Gao H,Cai JF,Shen Z,Zhao H

更新日期：2011-06-07 00:00:00

abstract：:Shear wave elastography (SWE) is a potential tool to non-invasively assess cardiac muscle stiffness. This study focused on the effect of the orthotropic material properties and mechanical loading on the performance of cardiac SWE, as it is known that these factors contribute to complex 3D anisotropic shear wave propag...

journal_title：Physics in medicine and biology

authors： Caenen A,Pernot M,Peirlinck M,Mertens L,Swillens A,Segers P

更新日期：2018-03-23 00:00:00

abstract：:Photon quality correction factors (kQy) for ionization chamber photon dosimetry in an epithermal neutron beam were determined according to a modified absorbed dose to water formalism which was extended to mixed radiation fields. We have studied two commercially available ionization chambers in the epithermal neutron b...

journal_title：Physics in medicine and biology

authors： Munck af Rosenschöld PM,Ceberg CP,Giusti V,Andreo P

更新日期：2002-07-21 00:00:00

abstract：:Calibration methods are investigated for the determination of bone density by the Compton scattering method. The scattered radiation from materials of different densities and dimensions is measured for this purpose. A function for the dependence of the intensity on these parameters is derived and compared with the exp...

journal_title：Physics in medicine and biology

authors： Leichter I,Weinreb A,Hazan G

更新日期：1980-07-01 00:00:00

abstract：:Factors affecting the accuracy of the in vivo measurement of cutaneous pigments and blood oxygenation by reflectance spectrophotometry have been examined. It was found that stray light, the amounts of haemoglobin and melanin, and the level of blood oxygenation all contributed to the measured reflectance and had to be ...

journal_title：Physics in medicine and biology

authors： Hajizadeh-Saffar M,Feather JW,Dawson JB

更新日期：1990-09-01 00:00:00

abstract：:A medical research protocol on clinical intravenous coronary angiography has been completed at the European Synchrotron Radiation Facility (ESRF) biomedical beamline. The aim was to investigate the accuracy of intravenous coronary angiography based on the K-edge digital subtraction technique for the detection of in-st...

journal_title：Physics in medicine and biology

authors： Sarnelli A,Nemoz C,Elleaume H,Estève F,Bertrand B,Bravin A

更新日期：2005-02-21 00:00:00

abstract：:At present, only a correction factor for photon transmission, k(l), is systematically applied for the entrance diaphragm of free-air chamber standards for air kerma. In the present work, the Monte Carlo code PENELOPE is used to re-evaluate k(l) for the BIPM standards and new correction factors are calculated for photo...

journal_title：Physics in medicine and biology

authors： Burns DT,Kessler C

更新日期：2009-05-07 00:00:00

abstract：:This paper investigates cone-beam tomography for a wide class of x-ray source trajectories called saddles. In particular, a mathematical analysis of the number of intersections between a saddle and an arbitrary plane is given. This analysis demonstrates that axially truncated cone-beam projections acquired along a sad...

journal_title：Physics in medicine and biology

authors： Pack JD,Noo F,Kudo H

更新日期：2004-06-07 00:00:00

abstract：:Fixed-pattern noise in electronic portal images (EPIs) is normally eliminated by dividing raw image data by an open-field calibration image (OFCI). However, for successful elimination, there must be exact registration between the two image sets. Any movement within the imaging system, such as that which occurs with ga...

journal_title：Physics in medicine and biology

authors： Kirby MC

更新日期：1996-11-01 00:00:00

abstract：:Measurements of standardized uptake values (SUV) can vary due to many causes, including respiratory motion. Various methodologies have been introduced to correct for motion in PET, with quiescent-period-gated (QPG) PET being the most popular approach. QPG has been shown to improve PET image quantification compared to ...

journal_title：Physics in medicine and biology

authors： Meier JG,Einstein SA,Diab RH,Erasmus LJ,Xu G,Mawlawi OR

更新日期：2019-05-16 00:00:00

abstract：:A circular scanning trajectory is and will likely remain a popular choice of trajectory in computed tomography (CT) imaging because it is easy to implement and control. Filtered-backprojection (FBP)-based algorithms have been developed previously for approximate and exact reconstruction of the entire image or a region...

journal_title：Physics in medicine and biology

authors： Pan X,Xia D,Zou Y,Yu L

更新日期：2004-09-21 00:00:00

abstract：:For conventional irradiation devices, the radiation isocenter accuracy is determined by star shot measurements on films. In magnetic resonance (MR)-guided radiotherapy devices, the results of this test may be altered by the magnetic field and the need to align the radiation and imaging isocenter may require a modifica...

journal_title：Physics in medicine and biology

authors： Dorsch S,Mann P,Lang C,Haering P,Runz A,Karger CP

更新日期：2018-05-29 00:00:00

abstract：:Beam tracking with scanned carbon ion radiotherapy achieves highly conformal target dose by steering carbon pencil beams to follow moving tumors using real-time magnetic deflection and range modulation. The purpose of this study was to evaluate the robustness of target dose coverage from beam tracking in light of posi...

journal_title：Physics in medicine and biology

authors： Eley JG,Newhauser WD,Richter D,Lüchtenborg R,Saito N,Bert C

更新日期：2015-02-21 00:00:00

abstract：:A formalism is proposed for the estimation of mean glandular dose for breast tomosynthesis, which is a simple extension of the UK, European and IAEA protocols for dosimetry in conventional projection mammography. The formalism introduces t-factors for the calculation of breast dose from a single projection and T-facto...

journal_title：Physics in medicine and biology

authors： Dance DR,Young KC,van Engen RE

更新日期：2011-01-21 00:00:00

abstract：:In (19)F MRI oximetry, a method used to image tumour hypoxia, perfluorocarbons serve as oxygenation markers. The goal of this study is to evaluate the impact of perfluorocarbon distribution and concentration in (19)F MRI oximetry through a computer simulation. The simulation studies the correspondence between (19)F me...

journal_title：Physics in medicine and biology

authors： Baete SH,Vandecasteele J,De Deene Y

更新日期：2011-04-21 00:00:00

abstract：:The artificial urinary sphincter should be long enough to prevent strangulation effects of the urethral tissue and short enough to avoid the improper dissection of the surrounding tissue. To optimize the sphincter length, the empirical three-parameter urethra compression model is proposed based on the mechanical prope...

journal_title：Physics in medicine and biology

authors： Marti F,Leippold T,John H,Blunschi N,Müller B

更新日期：2006-03-07 00:00:00

abstract：:Magnetoencephalography (MEG) is a non-invasive functional imaging modality based on the measurement of the external magnetic field produced by neural current sources within the brain. The reconstruction of the underlying sources is a severely ill-posed inverse problem typically tackled using either low-dimensional par...

journal_title：Physics in medicine and biology

authors： Jerbi K,Mosher JC,Baillet S,Leahy RM

更新日期：2002-02-21 00:00:00

abstract：:This study investigates the dosimetric impact of using population-based Hounsfield units (HUs) and ICRU-based HUs as a function of the number of tissue segments for bulk density assignment toward MRI-based treatment planning in the abdomen. To avoid potential geometric differences between CT and MR images, CT images r...

journal_title：Physics in medicine and biology

authors： Hsu SH,Zawisza I,O'Grady K,Peng Q,Tomé WA

更新日期：2018-07-24 00:00:00

abstract：:Cone-beam computed tomography (CBCT) has rapidly become a clinically useful imaging modality for image-guided radiation therapy. Unfortunately, CBCT images of the thorax are susceptible to artefacts due to scattered photons, beam hardening, lag in data acquisition, and respiratory motion during a slow scan. These limi...

journal_title：Physics in medicine and biology

authors： Disher B,Hajdok G,Wang A,Craig J,Gaede S,Battista JJ

更新日期：2013-06-21 00:00:00

abstract：:We evaluated the basic properties of a commercially available BANGkit gel dosimeter, which is a normoxic type of BANG gel. This gel-kit has the same composition as the BANG 3 gel, but is fully oxygenated. To exclude oxygen, oxygen scavenging ascorbic acid and copper sulfate as a catalyst are used. The properties that ...

journal_title：Physics in medicine and biology

authors： Murakami Y,Nakashima T,Watanabe Y,Akimitsu T,Matsuura K,Kenjo M,Kaneyasu Y,Wadasaki K,Hirokawa Y,Ito K

更新日期：2007-04-21 00:00:00

abstract：:Talbot-Lau interferometry (TLI) provides additional contrast modes for x-ray imaging that are complementary to conventional absorption radiography. TLI is particularly interesting because it is one of the few practical methods for realizing phase contrast with x-rays that is compatible with large-spot high power x-ray...

journal_title：Physics in medicine and biology

authors： Zan G,Vine DJ,Yun W,Lewis SJY,Wang Q,Wang G

更新日期：2020-02-04 00:00:00

abstract：:Beam hardening is inevitable due to the polychromatic X-ray spectrum and energy-dependent attenuation coefficients of materials, leading to the underestimation of artifacts arising from projection data, especially on metal regions. State-of-the-art research on beam-hardening artifacts is based on a numerical method th...

journal_title：Physics in medicine and biology

authors： Hur J,Kim D,Shin YG,Lee H

更新日期：2021-01-26 00:00:00

abstract：:In this study we present a three-dimensional (3D) reconstruction algorithm for magneto-acoustic tomography with magnetic induction (MAT-MI) based on the characteristics of the ultrasound transducer. The algorithm is investigated to solve the blur problem of the MAT-MI acoustic source image, which is caused by the ultr...

journal_title：Physics in medicine and biology

authors： Ma R,Zhou X,Zhang S,Yin T,Liu Z

更新日期：2016-12-21 00:00:00

abstract：:A micro-multileaf collimator (microMLC) for stereotactic radiosurgery is used for determination of the spatial intensity distribution of the photon source of a linear accelerator. The method is based on grid field dose measurements using film dosimetry and is easy to perform. Since the microMLC does not allow 'direct'...

journal_title：Physics in medicine and biology

authors： Treuer H,Hoevels M,Luyken K,Hunsche S,Kocher M,Müller RP,Sturm V

更新日期：2003-08-07 00:00:00

abstract：:The absolute dose rate around beta sources for intravascular brachytherapy was measured with thin thermoluminescent (TL) dosimeters and radiochromic film. The calibration of these dosimeters was performed at the dose maximum in a 6 MeV electron beam of a linear accelerator. Compared to the values given by the manufact...

journal_title：Physics in medicine and biology

authors： Piessens M,Reynaert N

更新日期：2000-08-01 00:00:00

abstract：:Accurate real-time prediction of respiratory motion is desirable for effective motion management in radiotherapy for lung tumor targets. Recently, nonparametric methods have been developed and their efficacy in predicting one-dimensional respiratory-type motion has been demonstrated. To exploit the correlation among v...

journal_title：Physics in medicine and biology

authors： Ruan D,Keall P

更新日期：2010-06-07 00:00:00

abstract：:A number of heating sources are available for minimally invasive thermal therapy of tumours. The purpose of this work was to compare, theoretically, the heating characteristics of interstitial microwave, laser and ultrasound sources in three tissue sites: breast, brain and liver. Using a numerical method, the heating ...

journal_title：Physics in medicine and biology

authors： Skinner MG,Iizuka MN,Kolios MC,Sherar MD

更新日期：1998-12-01 00:00:00

abstract：:The relative biological effectiveness (RBE) of protons varies with multiple physical and biological factors. Phenomenological RBE models have been developed to include such factors in the estimation of a variable RBE, in contrast to the clinically applied constant RBE of 1.1. In this study, eleven published phenomenol...

journal_title：Physics in medicine and biology

authors： Rørvik E,Fjæra LF,Dahle TJ,Dale JE,Engeseth GM,Stokkevåg CH,Thörnqvist S,Ytre-Hauge KS

更新日期：2018-09-13 00:00:00