Abstract：
:Although x-ray mammography is widely developed for breast tumour detection, it suffers from spatial superposition in its two-dimensional (2D) representation of a three-dimensional (3D) breast structure. Accordingly, 3D breast imaging, such as cone-beam computed tomography (CT), arises at the historic moment. In this paper, we theoretically elucidate the spatial superposition effect associated with x-ray mammography on breast tumour detection. This explanation is based on the line integral of x-ray traversing a composite breast model. As a result, we can characterize the difficulty of detecting small tumours in terms of local intensity contrast in x-ray images. In comparison, we also introduce cone-beam CT breast imaging for 3D breast volume representation, which offers advantages for breast mass segmentation and measurement. The discussion is demonstrated with an experiment with a breast surgical specimen. In conclusion, we strongly believe that 3D volumetric representation allows for more accurate breast tumour detection.
journal_name
Phys Med Bioljournal_title
Physics in medicine and biologyauthors
Chen Z,Ning Rdoi
10.1088/0031-9155/48/14/312subject
Has Abstractpub_date
2003-07-21 00:00:00pages
2217-28issue
14eissn
0031-9155issn
1361-6560journal_volume
48pub_type
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