Fully three-dimensional positron emission tomography.

abstract：:The S-value is a standard measure in cellular dosimetry. S-values are calculated by applying analytical methods or by Monte Carlo simulation. In Monte Carlo simulation, particles are either tracked individually event-by-event or close events are condensed and processed collectively in different steps. Both of these me...

journal_title：Physics in medicine and biology

authors： Tajik-Mansoury MA,Rajabi H,Mozdarani H

更新日期：2017-03-07 00:00:00

abstract：:Recent acute shortage of medical radioisotopes prompted investigations into alternative methods of production and the use of a cyclotron and ¹⁰⁰Mo(p,2n)(99m)Tc reaction has been considered. In this context, the production yields of (99m)Tc and various other radioactive and stable isotopes which will be created in the ...

journal_title：Physics in medicine and biology

authors： Celler A,Hou X,Bénard F,Ruth T

更新日期：2011-09-07 00:00:00

abstract：:In this paper, we investigate an off-line strategy to incorporate inter-fraction organ motion in IMRT treatment planning. It was suggested that inverse planning could be based on a probability distribution of patient geometries instead of a single snap shot. However, this concept is connected to two intrinsic problems...

journal_title：Physics in medicine and biology

authors： Unkelbach J,Oelfke U

更新日期：2004-09-07 00:00:00

abstract：:As known, in cancer therapy with ion beams the relative biological effectiveness (RBE) of ions changes in the course of their propagation in tissues. Such changes are caused not only by increasing the linear energy transfer (LET) of beam particles with the penetration depth towards the Bragg peak, but also by nuclear ...

journal_title：Physics in medicine and biology

authors： Dewey S,Burigo L,Pshenichnov I,Mishustin I,Bleicher M

更新日期：2017-06-27 00:00:00

abstract：:The coincidence time resolution (CTR) becomes a key parameter of 511 keV gamma detection in time of flight positron emission tomography (TOF-PET). This is because additional information obtained through timing leads to a better noise suppression and therefore a better signal to noise ratio in the reconstructed image. ...

journal_title：Physics in medicine and biology

authors： Nemallapudi MV,Gundacker S,Lecoq P,Auffray E,Ferri A,Gola A,Piemonte C

更新日期：2015-06-21 00:00:00

abstract：:A photoluminescent thermometer, based on the transient emission response of a europium-activated calcium sulphide phosphor, is described in detail. This optical thermometry system has special advantages for temperature measurements in microwave and RF fields and potential application in electromagnetically induced cli...

journal_title：Physics in medicine and biology

authors： Samulski TV,Chopping PT,Haas B

更新日期：1982-01-01 00:00:00

abstract：:The silicon photomultiplier (Si-PM) is a promising photo-detector for PET for use in magnetic resonance imaging (MRI) systems because it has high gain and is insensitive to static magnetic fields. Recently we developed a Si-PM-based depth-of-interaction PET system for small animals and performed simultaneous measureme...

journal_title：Physics in medicine and biology

authors： Yamamoto S,Watabe T,Watabe H,Aoki M,Sugiyama E,Imaizumi M,Kanai Y,Shimosegawa E,Hatazawa J

更新日期：2012-01-21 00:00:00

abstract：:Fluorescence molecular tomography (FMT) is widely used in preclinical oncology research. FMT is the only imaging technique able to provide 3D distribution of fluorescent probes within thick highly scattering media. However, its integration into clinical medicine has been hampered by its low spatial resolution caused b...

journal_title：Physics in medicine and biology

authors： Nouizi F,Kwong TC,Ruiz J,Cho J,Chan YW,Ikemura K,Erkol H,Sampathkumaran U,Gulsen G

更新日期：2019-01-22 00:00:00

abstract：:Component-based normalization is a method used to compensate for the sensitivity of each of the lines of response acquired in positron emission tomography. This method consists of modelling the sensitivity of each line of response as a product of multiple factors, which can be classified as time-invariant, time-varian...

journal_title：Physics in medicine and biology

authors： Belzunce MA,Reader AJ

更新日期：2016-05-07 00:00:00

abstract：:Temperature distributions resulting from hyperthermia treatments on isolated perfused bovine tongues were compared with simulations by a treatment planning system. The aim was to test whether the discrete vessel model used for the treatment planning is able to predict correct generic temperature distributions. Tongues...

journal_title：Physics in medicine and biology

authors： Raaymakers BW,Crezee J,Lagendijk JJ

更新日期：1998-05-01 00:00:00

abstract：:Ankylosing spondylitis is a disease characterized by abnormal bone formation (syndesmophyte) at the margins of inter-vertebral disc spaces. Syndesmophyte growth is currently typically monitored by the visual inspection of radiographs. The limitations inherent to the modality (2D projection of a 3D object) and rater (q...

journal_title：Physics in medicine and biology

authors： Tan S,Yao J,Yao L,Ward MM

更新日期：2012-07-21 00:00:00

abstract：:The purpose of this work is to develop and test a method to estimate the relative and absolute absorbed radiation dose from axial and spiral CT scans using a Monte Carlo approach. Initial testing was done in phantoms and preliminary results were obtained from a standard mathematical anthropomorphic model (MIRD V) and ...

journal_title：Physics in medicine and biology

authors： Jarry G,DeMarco JJ,Beifuss U,Cagnon CH,McNitt-Gray MF

更新日期：2003-08-21 00:00:00

abstract：:In vivo neutron activation analysis was used to measure total body sodium and chlorine in 18 male and 18 female normal adults. Corrections for body size were developed. Normalisation factors were derived which enable the prediction of the normal levels of sodium and chlorine in a subject. The coefficient of variation ...

journal_title：Physics in medicine and biology

authors： Kennedy NS,Eastell R,Smith MA,Tothill P

更新日期：1983-03-01 00:00:00

abstract：:A dynamic-contrast-enhanced magnetic resonance imaging (DCE-MRI) dataset consists of many imaging frames, often acquired both before and after contrast injection. Due to the length of time spent acquiring images, patient motion is likely and image re-alignment or registration is required before further analysis such a...

journal_title：Physics in medicine and biology

authors： Melbourne A,Hipwell J,Modat M,Mertzanidou T,Huisman H,Ourselin S,Hawkes DJ

更新日期：2011-12-21 00:00:00

abstract：:In proton scanning systems that employ active energy variation for depth modulation, a switch of the particle energy might typically require 1-2 s. For plans comprising many energy slices, these seconds could sum up to a non-negligible fraction of the total treatment duration. We have applied the Nyquist-Shannon sampl...

journal_title：Physics in medicine and biology

authors： Kang JH,Wilkens JJ,Oelfke U

更新日期：2008-05-07 00:00:00

abstract：:RapidArc, recently released by Varian Medical Systems, is a novel extension of IMRT in which an optimized 3D dose distribution may be delivered in a single gantry rotation of 360 degrees or less. The purpose of this study was to investigate the accuracy of the analytical anisotropic algorithm (AAA), the sole algorithm...

journal_title：Physics in medicine and biology

authors： Gagne IM,Ansbacher W,Zavgorodni S,Popescu C,Beckham WA

更新日期：2008-12-21 00:00:00

abstract：:We report a simulation study on diffuse reflective optical computed tomography, in which continuous-wave sources and detectors are placed on the plane surface of a semi-infinite body. We adopted a simple Tikhonov regularization in the inverse problem and demonstrated the feasibility of three-dimensional reconstruction...

journal_title：Physics in medicine and biology

authors： Endoh R,Suzuki A,Fujii M,Nakayama K

更新日期：2004-05-21 00:00:00

abstract：:Despite over ten years of in vitro investigations of ultrasound contrast agents, the level of understanding of their behaviour in ultrasound fields is limited. Several problems associated with these investigations, particular to the nature of contrast agents, are discussed. Using a commercial scanner the RF normalized...

journal_title：Physics in medicine and biology

authors： Sboros V,Ramnarine KV,Moran CM,Pye SD,McDicken WN

更新日期：2002-12-07 00:00:00

abstract：:Changes in the relative biological effectiveness (RBE) of the radiation-induced cell killing of human salivary glands (HSG) were assessed along the Bragg peak of a 60 MeV clinical proton beam by means of coupling biophysical models with the results of Monte Carlo radiation transport simulations and experimental measur...

journal_title：Physics in medicine and biology

authors： Parisi A,Olko P,Swakoń J,Horwacik T,Jabłoński H,Malinowski L,Nowak T,Struelens L,Vanhavere F

更新日期：2020-01-10 00:00:00

abstract：:Corrections for room scatter, [ksc(d, H)]RM, were derived using Monte Carlo methods for rooms of various sizes, including the brachytherapy treatment room, in which primary air kerma strength standardization of a remote afterloading microSelectron 192Ir HDR source was carried out, using a 60 cm3 spherical graphite ion...

journal_title：Physics in medicine and biology

authors： Selvam TP,Rajan KN,Nagarajan PS,Sethulakshmi P,Bhatt BC

更新日期：2001-09-01 00:00:00

abstract：:The analysis of (x-ray) mammograms remains qualitative, relying on the judgement of clinicians. We present a novel method to compute a quantitative, normalized measure of tissue radiodensity traversed by the primary beam incident on each pixel of a mammogram, a measure we term the standard attenuation rate (SAR). SAR ...

journal_title：Physics in medicine and biology

authors： Tromans CE,Cocker MR,Brady SM

更新日期：2012-10-21 00:00:00

abstract：:The purpose of this work is to provide an evaluation of the mean glandular dose (MGD) for breast computed tomography (CT) with synchrotron radiation in an axial scanning configuration with a partial or total organ volume irradiation, for the in vivo program of breast CT ongoing at the ELETTRA facility (Trieste, Italy)...

journal_title：Physics in medicine and biology

authors： Mettivier G,Fedon C,Di Lillo F,Longo R,Sarno A,Tromba G,Russo P

更新日期：2016-01-21 00:00:00

abstract：:We have developed an impedance magnetocardiogram (IMCG) system to detect the change of magnetic field corresponding to changes in blood volume in the heart. A low magnetic field from the electrical activity of the human heart--the so-called magnetocardiogram (MCG)--can be simultaneously detected by using this system. ...

journal_title：Physics in medicine and biology

authors： Kandori A,Miyashita T,Suzuki D,Yokosawa K,Tsukada K

更新日期：2001-02-01 00:00:00

abstract：:The purpose of this work is to develop a validated Geant4 simulation model of a whole-body prototype PET scanner constructed from the four-layer depth-of-interaction detectors developed at the National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Japan. T...

journal_title：Physics in medicine and biology

authors： Ahmed AM,Chacon A,Rutherford H,Akamatsu G,Mohammadi A,Nishikido F,Tashima H,Yoshida E,Yamaya T,Franklin DR,Rosenfeld A,Guatelli S,Safavi-Naeini M

更新日期：2020-12-18 00:00:00

abstract：:In this paper we present a novel method of reducing the dosimetric effects of the finite leaf width of a multileaf collimator (MLC) in conformal and intensity modulated radiotherapy (IMRT). This is achieved by decomposing the required high-resolution fluence distribution into two orthogonal components, which are deliv...

journal_title：Physics in medicine and biology

authors： Evans PM,Partridge M

更新日期：2000-03-01 00:00:00

abstract：:The use of deformable image registration methods in the context of adaptive radiotherapy leads to uncertainties in the simulation of the administered dose distributions during the treatment course. Evaluation of these methods is a prerequisite to decide if a plan adaptation will improve the individual treatment. Curre...

journal_title：Physics in medicine and biology

authors： Teske H,Bartelheimer K,Meis J,Bendl R,Stoiber EM,Giske K

更新日期：2017-06-21 00:00:00

abstract：:Several applications in nuclear medicine require absolute activity quantification of single photon emission computed tomography images. Obtaining a repeatable calibration factor that converts voxel values to activity units is essential for these applications. Because source preparation and measurement of the source ac...

journal_title：Physics in medicine and biology

authors： Anizan N,Wang H,Zhou XC,Wahl RL,Frey EC

更新日期：2015-02-07 00:00:00

abstract：:Various lead attenuation techniques to determine the fast neutron sensitivity kU of a photon dosemeter are reviewed and a modified method is proposed to determine the kU value of a commercially available Geiger--Müller detector. The dependence on the 'effective' photon energy of the gamma-component of the mixed n--gam...

journal_title：Physics in medicine and biology

authors： Hough JH

更新日期：1979-07-01 00:00:00

abstract：:In this work we present the first delivery of intensity modulated arc therapy on the Elekta Unity 1.5 T MR-linac. The machine's current IMRT based control system was modified suitably to enable dynamic delivery of radiation, for the purpose of exploring MRI-guided radiation therapy adaptation modes in a research setti...

journal_title：Physics in medicine and biology

authors： Kontaxis C,Woodhead PL,Bol GH,Lagendijk JJW,Raaymakers BW

更新日期：2020-12-23 00:00:00

abstract：:Advanced radiotherapeutical techniques like intensity-modulated radiation therapy (IMRT) are based on an accurate knowledge of the location of the radiation target. An accurate dose delivery, therefore, requires a method to account for the inter- and intrafractional target motion and the target deformation occurring d...

journal_title：Physics in medicine and biology

authors： Tacke M,Nill S,Oelfke U

更新日期：2007-11-21 00:00:00