当前位置： SCI文献检索 > PHYSICS IN MEDICINE AND BIOLOGY期刊下所有文献 > The effect of motion correction on pharmacokinetic parameter estimation in dynamic-contrast-enhanced MRI.

The effect of motion correction on pharmacokinetic parameter estimation in dynamic-contrast-enhanced MRI.

Abstract：

:A dynamic-contrast-enhanced magnetic resonance imaging (DCE-MRI) dataset consists of many imaging frames, often acquired both before and after contrast injection. Due to the length of time spent acquiring images, patient motion is likely and image re-alignment or registration is required before further analysis such as pharmacokinetic model fitting. Non-rigid image registration procedures may be used to correct motion artefacts; however, a careful choice of registration strategy is required to reduce misregistration artefacts associated with enhancing features. This work investigates the effect of registration on the results of model-fitting algorithms for 52 DCE-MR mammography cases for 14 patients. Results are divided into two sections: a comparison of registration strategies in which a DCE-MRI-specific algorithm is preferred in 50% of cases, followed by an investigation of parameter changes with known applied deformations, inspecting the effect of magnitude and timing of motion artefacts. Increased motion magnitude correlates with increased model-fit residual and is seen to have a strong influence on the visibility of strongly enhancing features. Motion artefacts in images close to the contrast agent arrival have a disproportionate effect on discrepancies in parameter estimation. The choice of algorithm, magnitude of motion and timing of the motion are each shown to influence estimated pharmacokinetic parameters even when motion magnitude is small.

journal_name

Phys Med Biol

journal_title

Physics in medicine and biology

authors

Melbourne A,Hipwell J,Modat M,Mertzanidou T,Huisman H,Ourselin S,Hawkes DJ

doi

10.1088/0031-9155/56/24/001

subject

Has Abstract

pub_date

2011-12-21 00:00:00

pages

7693-708

issue

24

eissn

0031-9155

issn

1361-6560

pii

S0031-9155(11)03301-X

journal_volume

56

pub_type

杂志文章

相关文献

PHYSICS IN MEDICINE AND BIOLOGY文献大全
  • Assessment of the effects of pixel loss on image quality in direct digital radiography.

    abstract：:Modern digital radiographic 'flat panel' detectors can exhibit a progressive form of image degradation arising from non-functioning pixels. The effect of these 'dead pixels' on the quantitive image quality measures of modulation transfer function (MTF), noise power spectrum (NPS) and detective quantum efficiency (DQE)...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/0031-9155/49/6/008

    authors： Padgett R,Kotre CJ

    更新日期：2004-03-21 00:00:00

  • Structural and practical identifiability of dual-input kinetic modeling in dynamic PET of liver inflammation.

    abstract：:Dynamic 18F-FDG PET with tracer kinetic modeling has the potential to noninvasively evaluate human liver inflammation using the FDG blood-to-tissue transport rate K 1. Accurate kinetic modeling of dynamic liver PET data and K 1 quantification requires the knowledge of dual-blood input function from the hepatic artery ...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/1361-6560/ab1f29

    authors： Zuo Y,Sarkar S,Corwin MT,Olson K,Badawi RD,Wang G

    更新日期：2019-09-05 00:00:00

  • Analytical propagation of errors in dynamic SPECT: estimators, degrading factors, bias and noise.

    abstract：:Dynamic SPECT is a relatively new technique that may potentially benefit many imaging applications. Though similar to dynamic PET, the accuracy and precision of dynamic SPECT parameter estimates are degraded by factors that differ from those encountered in PET. In this work we formulate a methodology for analytically ...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/0031-9155/44/8/311

    authors： Kadrmas DJ,DiBella EV,Huesman RH,Gullberg GT

    更新日期：1999-08-01 00:00:00

  • Should image rotation be addressed during routine cone-beam CT quality assurance?

    abstract：:The purpose of this study is to investigate whether quality assurance (QA) for cone-beam computed tomography (CBCT) image rotation is necessary in order to ensure the accuracy of CBCT based image-guided radiation therapy (IGRT) and adaptive radiotherapy (ART). Misregistration of angular coordinates during CBCT acquisi...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/0031-9155/58/4/1059

    authors： Ayan AS,Lin H,Yeager C,Deville C,McDonough J,Zhu TC,Anderson N,Bar Ad V,Lu HM,Both S

    更新日期：2013-02-21 00:00:00

  • Fourier rebinning of time-of-flight PET data.

    abstract：:This paper explores fast reconstruction strategies for 3D time-of-flight (TOF) positron emission tomography (PET), based on 2D data rebinning. Starting from pre-corrected 3D TOF data, a rebinning algorithm estimates for each transaxial slice the 2D TOF sinogram that would have been acquired by a single-ring scanner. T...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/0031-9155/50/12/002

    authors： Defrise M,Casey ME,Michel C,Conti M

    更新日期：2005-06-21 00:00:00

  • Monte Carlo simulations of a nozzle for the treatment of ocular tumours with high-energy proton beams.

    abstract：:By the end of 2002, 33 398 patients worldwide had been treated with proton radiotherapy, 10 829 for eye diseases. The dose prediction algorithms used today for ocular proton therapy treatment planning rely on parameterizations of measured proton dose distributions, i.e., broad-beam and pencil-beam techniques, whose pr...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/0031-9155/50/22/002

    authors： Newhauser W,Koch N,Hummel S,Ziegler M,Titt U

    更新日期：2005-11-21 00:00:00

  • Methodologies in the modeling of combined chemo-radiation treatments.

    abstract：:The variety of treatment options for cancer patients has increased significantly in recent years. Not only do we combine radiation with surgery and chemotherapy, new therapeutic approaches such as immunotherapy and targeted therapies are starting to play a bigger role. Physics has made significant contributions to rad...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/0031-9155/61/21/R344

    authors： Grassberger C,Paganetti H

    更新日期：2016-11-07 00:00:00

  • A numerical study on the influence of vulnerable plaque composition on intravascular thermography measurements.

    abstract：:Intracoronary thermography is a technique that measures lumen wall temperatures for vulnerable plaque detection. In this paper the influence of vulnerable plaque composition on lumen wall temperatures was studied numerically. Concerning the vulnerable plaque heat generation, the location of the heat source and its hea...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/0031-9155/51/22/010

    authors： ten Have AG,Gijsen FJ,Wentzel JJ,Slager CJ,Serruys PW,van der Steen AF

    更新日期：2006-11-21 00:00:00

  • Optimisation of the imaging and dosimetric characteristics of an electronic portal imaging device employing plastic scintillating fibres using Monte Carlo simulations.

    abstract：:A Monte Carlo model of a novel electronic portal imaging device (EPID) has been developed using Geant4 and its performance for imaging and dosimetry applications in radiotherapy has been characterised. The EPID geometry is based on a physical prototype under ongoing investigation and comprises an array of plastic scin...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/0031-9155/59/22/6827

    authors： Blake SJ,McNamara AL,Vial P,Holloway L,Kuncic Z

    更新日期：2014-11-21 00:00:00

  • Significance of background optical properties, time-resolved information and optode arrangement in diffuse optical imaging of term neonates.

    abstract：:The significance of accurate knowledge of background optical properties and time-resolved information in reconstructing images of hemodynamic changes in the neonatal brain from diffuse optical imaging data was studied using Monte Carlo (MC) simulation. A segmented anatomical magnetic resonance (MR) image and literatur...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/0031-9155/54/3/005

    authors： Heiskala J,Hiltunen P,Nissilä I

    更新日期：2009-02-07 00:00:00

  • Golden beam data for proton pencil-beam scanning.

    abstract：:Proton, as well as other ion, beams applied by electro-magnetic deflection in pencil-beam scanning (PBS) are minimally perturbed and thus can be quantified a priori by their fundamental interactions in a medium. This a priori quantification permits an optimal reduction of characterizing measurements on a particular PB...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/0031-9155/57/5/1147

    authors： Clasie B,Depauw N,Fransen M,Gomà C,Panahandeh HR,Seco J,Flanz JB,Kooy HM

    更新日期：2012-03-07 00:00:00

  • The radiation dose from a proposed measurement of arsenic and selenium in human skin.

    abstract：:Dose measurements following 10 min irradiations with a portable x-ray fluorescence spectrometer composed of a miniature x-ray tube and a silicon PiN diode detector were performed using thermoluminescent dosimeters consisting of LiF:Mg,Ti chips of 3 mm diameter and 0.4 mm thickness. The table-top setup of the spectrome...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/0031-9155/55/18/015

    authors： Gherase MR,Mader JE,Fleming DE

    更新日期：2010-09-21 00:00:00

  • Dosimetric and workflow evaluation of first commercial synthetic CT software for clinical use in pelvis.

    abstract：:To evaluate a commercial synthetic CT (syn-CT) software for use in prostate radiotherapy. Twenty-five prostate patients underwent CT and MR simulation scans in treatment position on a 3T MR scanner. A commercially available MR protocol was used that included a T2w turbo spin-echo sequence for soft-tissue contrast and ...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/1361-6560/aa5452

    authors： Tyagi N,Fontenla S,Zhang J,Cloutier M,Kadbi M,Mechalakos J,Zelefsky M,Deasy J,Hunt M

    更新日期：2017-04-21 00:00:00

  • First experimental evidence of the feasibility of multi-color magnetic particle imaging.

    abstract：:Magnetic particle imaging is a new approach to visualizing magnetic nanoparticles. It is capable of 3D real-time in vivo imaging of particles injected into the blood stream and is a candidate for medical imaging applications. To date, only one particle type has been imaged at a time, however, the ability to separate s...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/0031-9155/60/5/1775

    authors： Rahmer J,Halkola A,Gleich B,Schmale I,Borgert J

    更新日期：2015-03-07 00:00:00

  • A novel linear programming approach to fluence map optimization for intensity modulated radiation therapy treatment planning.

    abstract：:We present a novel linear programming (LP) based approach for efficiently solving the intensity modulated radiation therapy (IMRT) fluence-map optimization (FMO) problem to global optimality. Our model overcomes the apparent limitations of a linear-programming approach by approximating any convex objective function by...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/0031-9155/48/21/005

    authors： Romeijn HE,Ahuja RK,Dempsey JF,Kumar A,Li JG

    更新日期：2003-11-07 00:00:00

  • Potential applications of the quantitative susceptibility mapping (QSM) in MR-guided radiation therapy.

    abstract：:Magnetic resonance-guided radiation therapy (MR-GRT) offers great potential to improve radiation treatment outcomes by providing more accurate and patient-tailored therapy. Despite superior soft tissue contrast in MRI, one of the challenges towards MRI-only workflows is that the process often requires some sort of 'MR...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/1361-6560/ab2623

    authors： Nosrati R,Paudel M,Ravi A,Pejovic-Milic A,Morton G,Stanisz GJ

    更新日期：2019-07-16 00:00:00

  • Percentile-specific computational phantoms constructed from ICRP mesh-type reference computational phantoms (MRCPs).

    abstract：:Recently, the Task Group 103 of the International Commission on Radiological Protection (ICRP) has developed new mesh-type reference computational phantoms (MRCPs) for adult male and female. When compared to the current voxel-type reference computational phantoms in ICRP Publication 110, the MRCPs have several advanta...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/1361-6560/aafcdb

    authors： Lee H,Yeom YS,Nguyen TT,Choi C,Han H,Shin B,Zhang X,Kim CH,Chung BS,Zankl M

    更新日期：2019-02-05 00:00:00

  • Reconstructing uniformly attenuated rotating slant-hole SPECT projection data using the DBH method.

    abstract：:This work applies a previously developed analytical algorithm to the reconstruction problem in a rotating multi-segment slant-hole (RMSSH) SPECT system. The RMSSH collimator has greater detection efficiency than the parallel-hole collimator with comparable spatial resolution at the expense of limited common volume-of-...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/0031-9155/54/13/024

    authors： Huang Q,Xu J,Tsui BM,Gullberg GT

    更新日期：2009-07-07 00:00:00

  • Computational errors of the induced electric field in voxelized and tetrahedral anatomical head models exposed to spatially uniform and localized magnetic fields.

    abstract：:At low and intermediate frequencies, the strength of the induced electric field is used as dosimetric quantity for human protection in the International Commission on Non-Ionizing Radiation Protection (ICNIRP) guidelines. To compute the induced electric field, numerical methods based on anatomically realistic voxel mo...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/1361-6560/ab5dfb

    authors： Soldati M,Laakso I

    更新日期：2020-01-10 00:00:00

  • Assessment of thermal effects in a model of the human head implanted with a wireless active microvalve for the treatment of glaucoma creating a filtering bleb.

    abstract：:A 3D anatomical computational model is developed to assess thermal effects due to exposure to the electromagnetic field required to power a new investigational active implantable microvalve for the treatment of glaucoma. Such a device, located in the temporal superior eye quadrant, produces a filtering bleb, which is ...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/1361-6560/aa5dae

    authors： Schaumburg F,Guarnieri FA

    更新日期：2017-05-07 00:00:00

  • Assessment of rigid multi-modality image registration consistency using the multiple sub-volume registration (MSR) method.

    abstract：:Registration of different imaging modalities such as CT, MRI, functional MRI (fMRI), positron (PET) and single photon (SPECT) emission tomography is used in many clinical applications. Determining the quality of any automatic registration procedure has been a challenging part because no gold standard is available to e...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/0031-9155/50/10/N01

    authors： Ceylan C,van der Heide UA,Bol GH,Lagendijk JJ,Kotte AN

    更新日期：2005-05-21 00:00:00

  • Measuring the acoustoelectric interaction constant using ultrasound current source density imaging.

    abstract：:Ultrasound current source density imaging (UCSDI) exploits the acoustoelectric (AE) effect, an interaction between ultrasound pressure and electrical resistivity, to map electrical conduction in the heart. The conversion efficiency for UCSDI is determined by the AE interaction constant K, a fundamental property of all...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/0031-9155/57/19/5929

    authors： Li Q,Olafsson R,Ingram P,Wang Z,Witte R

    更新日期：2012-10-07 00:00:00

  • 4D digital tomosynthesis image reconstruction using brute force-based adaptive total variation (BF-ATV) in a prototype LINAC system.

    abstract：:Respiratory-correlated cone-beam CT (CBCT) not only inhibits rapid scanning due to the slow speed of the LINAC head gantry rotation, but its implementation for routine patient imaging is impractical because of the high radiation dose delivered during the process. Digital tomosynthesis (DTS) is a potentially faster tec...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/1361-6560/ab0d50

    authors： Choi S,Lee S,Kang YN,Hsieh SS,Kim HJ

    更新日期：2019-05-02 00:00:00

  • An optimized leaf-setting algorithm for beam intensity modulation using dynamic multileaf collimators.

    abstract：:A leaf-setting algorithm is developed for generating arbitrary beam intensity profiles in discrete levels using dynamic multileaf collimators (DMLCs). The algorithm starts with the algebraic expression for the area under the beam profile. It is shown that the coefficients in this expression can be transformed into the...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/0031-9155/43/6/019

    authors： Ma L,Boyer AL,Xing L,Ma CM

    更新日期：1998-06-01 00:00:00

  • Reduced-order constrained optimization in IMRT planning.

    abstract：:This paper presents a new algorithm for constrained intensity-modulated radiotherapy (IMRT) planning, made tractable by a dimensionality reduction using a set of plans obtained by fast, unconstrained optimizations. The main result is to reduce planning time by an order of magnitude, producing viable five field prostat...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/0031-9155/53/23/007

    authors： Lu R,Radke RJ,Yang J,Happersett L,Yorke E,Jackson A

    更新日期：2008-12-07 00:00:00

  • An age-dependent series of eye models for radiation dosimetry.

    abstract：:Several studies have been appeared, up to now, that indicate the effect of accurate simulation on dose received by different substructures of the eye, irradiated by external beams of short-range radiation such as electron. Different representations of the eye have consequently been introduced. Their accuracies depend ...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/1361-6560/ab2059

    authors： Vejdani-Noghreiyan A,Ebrahimi-Khankook A

    更新日期：2019-07-02 00:00:00

  • Use of forward projection to correct patient motion during SPECT imaging.

    abstract：:We have developed an iterative method to correct axial and tangential patient motion occurring during tomographic acquisition. The method uses axial images reconstructed from the uncorrected projection images, which are then forward projected to form a basis for registering the original planar images and, in the proce...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/0031-9155/43/1/011

    authors： Lee KJ,Barber DC

    更新日期：1998-01-01 00:00:00

  • Dictionary learning for data recovery in positron emission tomography.

    abstract：:Compressed sensing (CS) aims to recover images from fewer measurements than that governed by the Nyquist sampling theorem. Most CS methods use analytical predefined sparsifying domains such as total variation, wavelets, curvelets, and finite transforms to perform this task. In this study, we evaluated the use of dicti...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/0031-9155/60/15/5853

    authors： Valiollahzadeh S,Clark JW,Mawlawi O

    更新日期：2015-08-07 00:00:00

  • Robust fluence map optimization via alternating direction method of multipliers with empirical parameter optimization.

    abstract：:For the treatment planning during intensity modulated radiation therapy (IMRT) or volumetric modulated arc therapy (VMAT), beam fluence maps can be first optimized via fluence map optimization (FMO) under the given dose prescriptions and constraints to conformally deliver the radiation dose to the targets while sparin...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/0031-9155/61/7/2838

    authors： Gao H

    更新日期：2016-04-07 00:00:00

  • The assessment of the non-equilibrium effect in the 'Patlak analysis' of Fdopa PET studies.

    abstract：:'Patlak analysis' is a common approach used in Fdopa PET studies to calculate the uptake constant (Ki) of the tracer. It is assumed in the Patlak analysis that the reversible compartment of tissue radioactivity used is in effective equilibrium with the tracer in plasma. Therefore, using the data prior to equilibrium i...

    journal_title：Physics in medicine and biology

    pub_type： 杂志文章

    doi：10.1088/0031-9155/40/7/007

    authors： Yu DC,Huang SC,Barrio JR,Phelps ME

    更新日期：1995-07-01 00:00:00