A method of improving the spatial resolution of treatments that involve a multileaf collimator.

abstract：:It has been demonstrated that gas-filled microbubble contrast agents, based on their volume changes, can serve as pressure probes in an MR field. It was recently reported that such an MR-based pressure measurement with microbubbles at 1.5 T must make use of microbubbles that have a volumetric magnetic susceptibility d...

journal_title：Physics in medicine and biology

authors： Dharmakumar R,Plewes DB,Wright GA

更新日期：2005-10-21 00:00:00

abstract：:A hydrogen clearance technique for the measurement of capillary blood flow in skeletal muscle (both resting and working) and the beating heart in experimental animals is described. Various methods for introducing the hydrogen into the region of measurement are compared, together with the appropriate methods for evalua...

journal_title：Physics in medicine and biology

authors： Harrison DK,Kessler M

更新日期：1989-10-01 00:00:00

abstract：:Clinical studies have established a strong benefit from adjuvant mild hyperthermia (HT) to radio- and chemotherapy for many tumor sites, including the head and neck (H&N). The recently developed HYPERcollar allows the application of local radiofrequency HT to tumors in the entire H&N. Treatment quality is optimized us...

journal_title：Physics in medicine and biology

authors： Paulides MM,Bakker JF,Hofstetter LW,Numan WC,Pellicer R,Fiveland EW,Tarasek M,Houston GC,van Rhoon GC,Yeo DT,Kotek G

更新日期：2014-05-07 00:00:00

abstract：:The formulation of intensity modulated radiation therapy (IMRT) planning aspects frequently uses the dose-volume histogram (DVH), whereas plan computations often happen in the more desirable convex IMRT optimization framework. Inspired by a recent publication of Zinchenko et al (2008 Phys. Med. Biol. 53 3231-50), this...

journal_title：Physics in medicine and biology

authors： Kratt K,Scherrer A

更新日期：2009-06-21 00:00:00

abstract：:The purpose of this study was to apply a novel method of multiscale echo texture analysis for distinguishing benign (hemangiomas) from malignant (hepatocellular carcinomas (HCCs) and metastases) focal liver lesions in B-mode ultrasound images. In this method, regions of interest (ROIs) extracted from within the lesion...

journal_title：Physics in medicine and biology

authors： Yoshida H,Casalino DD,Keserci B,Coskun A,Ozturk O,Savranlar A

更新日期：2003-11-21 00:00:00

abstract：:A full-field speckle interferometry method for non-contact and prospectively high speed Photoacoustic Tomography is introduced and evaluated as proof of concept. Thermoelastic pressure induced changes of the objects topography are acquired in a repetitive mode without any physical contact to the object. In order to ob...

journal_title：Physics in medicine and biology

authors： Horstmann J,Spahr H,Buj C,Münter M,Brinkmann R

更新日期：2015-05-21 00:00:00

abstract：:Skin toxicity has been reported for IMRT of head and neck cancer. The purpose of this study was to investigate the dose in the build-up region delivered by a 6 MV treatment plan for which important skin toxicity was observed. We also investigated if the different designs of the treatment head of an Elekta and a Varian...

journal_title：Physics in medicine and biology

authors： Paelinck L,De Wagter C,Van Esch A,Duthoy W,Depuydt T,De Neve W

更新日期：2005-02-07 00:00:00

abstract：:Coronary computed tomography angiography (cCTA) is a commonly used imaging modality for the evaluation of coronary artery disease. cCTA is generally reconstructed in multiple cardiac phases because different coronary arteries may be better visualized in some phases than in others due to the periodic cardiac motion. We...

journal_title：Physics in medicine and biology

authors： Hadjiiski L,Zhou C,Chan HP,Chughtai A,Agarwal P,Kuriakose J,Kazerooni E,Wei J,Patel S

更新日期：2014-08-21 00:00:00

abstract：:The Monte Carlo method is the most accurate method for radiotherapy dose calculations, if used correctly. However, any Monte Carlo dose calculation is burdened with statistical noise. In this paper, denoising of Monte Carlo dose distributions with a three-dimensional adaptive anisotropic diffusion method was investiga...

journal_title：Physics in medicine and biology

authors： Miao B,Jeraj R,Bao S,Mackie TR

更新日期：2003-09-07 00:00:00

abstract：:Ankylosing spondylitis is a disease characterized by abnormal bone formation (syndesmophyte) at the margins of inter-vertebral disc spaces. Syndesmophyte growth is currently typically monitored by the visual inspection of radiographs. The limitations inherent to the modality (2D projection of a 3D object) and rater (q...

journal_title：Physics in medicine and biology

authors： Tan S,Yao J,Yao L,Ward MM

更新日期：2012-07-21 00:00:00

abstract：:We examined the reasons for the reduction in response of a multidetector radiation counting system when operated at high count-rates and established a convenient method of correction which is accurate to within +/- 1% up to 0-6 X 10(5) counts per second. In its application the method uses the observed count-rates from...

journal_title：Physics in medicine and biology

authors： Oxby CB,Oldroyd B,Appleby DB

更新日期：1976-01-01 00:00:00

abstract：:Nanocarriers offer a promising approach to significantly improve therapeutic delivery to solid tumors as well as limit the side effects associated with anti-cancer agents. However, their relatively large size can negatively affect their ability to efficiently penetrate into more interior tumor regions, ultimately redu...

journal_title：Physics in medicine and biology

authors： Mohammadabadi A,Huynh RN,Wadajkar AS,Lapidus RG,Kim AJ,Raub CB,Frenkel V

更新日期：2020-06-22 00:00:00

abstract：:The 'EXACT3D' positron tomograph, which is now in routine clinical research use, was developed with the aim of achieving unprecedented sensitivity, high spatial and temporal resolution and simplicity of design using proven detector technology. It consists of six rings of standard detector blocks (CTI/Siemens EXACT HR+...

journal_title：Physics in medicine and biology

authors： Spinks TJ,Jones T,Bloomfield PM,Bailey DL,Miller M,Hogg D,Jones WF,Vaigneur K,Reed J,Young J,Newport D,Moyers C,Casey ME,Nutt R

更新日期：2000-09-01 00:00:00

abstract：:RapidArc, recently released by Varian Medical Systems, is a novel extension of IMRT in which an optimized 3D dose distribution may be delivered in a single gantry rotation of 360 degrees or less. The purpose of this study was to investigate the accuracy of the analytical anisotropic algorithm (AAA), the sole algorithm...

journal_title：Physics in medicine and biology

authors： Gagne IM,Ansbacher W,Zavgorodni S,Popescu C,Beckham WA

更新日期：2008-12-21 00:00:00

abstract：:The design, construction and use of a large-scale field-cycled proton-electron double-resonance imaging (FC-PEDRI) imager is described. The imager is based on a whole-body sized, vertical field, 59 mT permanent magnet. Field cycling is accomplished by the field compensation method, and uses a secondary, resistive magn...

journal_title：Physics in medicine and biology

authors： Lurie DJ,Foster MA,Yeung D,Hutchison JM

更新日期：1998-07-01 00:00:00

abstract：:For the first time, three-dimensional images of the newborn infant brain have been generated using measurements of transmitted light. A 32-channel time-resolved imaging system was employed, and data were acquired using custom-made helmets which couple source fibres and detector bundles to the infant head. Images have ...

journal_title：Physics in medicine and biology

authors： Hebden JC,Gibson A,Yusof RM,Everdell N,Hillman EM,Delpy DT,Arridge SR,Austin T,Meek JH,Wyatt JS

更新日期：2002-12-07 00:00:00

abstract：:Artifacts caused by patient breathing and movement during PET data acquisition affect image quality. Respiratory gating is commonly used to gate the list-mode PET data into multiple bins over a respiratory cycle. Non-rigid registration of respiratory-gated PET images can reduce motion artifacts and preserve count stat...

journal_title：Physics in medicine and biology

authors： Li T,Zhang M,Qi W,Asma E,Qi J

更新日期：2020-07-30 00:00:00

abstract：:Scatter correction is an essential technique to improve the image quality of cone-beam CT (CBCT). Although different scatter correction methods have been proposed in the literature, a standard solution is still being studied due to the limitations including accuracy, computation efficiency and generalization. In this ...

journal_title：Physics in medicine and biology

authors： Jiang Y,Yang C,Yang P,Hu X,Luo C,Xue Y,Xu L,Hu X,Zhang L,Wang J,Sheng K,Niu T

更新日期：2019-07-11 00:00:00

abstract：:This study examines the effectiveness of a single, first-order Arrhenius process in accurately modelling the thermally induced changes in the optical properties, particularly the reduced scattering coefficient, mu(s)', and the absorption coefficient, mu(a), of ex vivo rat prostate. Recent work has shown that mu(s)' ca...

journal_title：Physics in medicine and biology

authors： Skinner MG,Everts S,Reid AD,Vitkin IA,Lilge L,Sherar MD

更新日期：2000-05-01 00:00:00

abstract：:In x-ray based imaging of the breast, contrast between fibroglandular (Fg) tissue and adipose (Ad) tissue is a source of anatomic noise. The goal of this work was to validate by simulation and experiment a mathematical framework for modelling the Fg component of anatomic noise in digital mammograpy (DM) and dual-energ...

journal_title：Physics in medicine and biology

authors： Tanguay J,Lalonde R,Bjarnason TA,Yang CJ

更新日期：2019-10-23 00:00:00

abstract：:Dynamic positron emission tomography (PET) imaging can provide information about metabolic changes over time, used for kinetic analysis and auxiliary diagnosis. Existing deep learning-based reconstruction methods have too many trainable parameters and poor generalization, and require mass data to train the neural netw...

journal_title：Physics in medicine and biology

authors： Wang B,Liu H

更新日期：2020-10-13 00:00:00

abstract：:An overview of the theory of 4D image reconstruction for emission tomography is given along with a review of the current state of the art, covering both positron emission tomography and single photon emission computed tomography (SPECT). By viewing 4D image reconstruction as a matter of either linear or non-linear par...

journal_title：Physics in medicine and biology

authors： Reader AJ,Verhaeghe J

更新日期：2014-11-21 00:00:00

abstract：:Chronic liver disease (CLD) is currently one of the major causes of death worldwide. If not treated, it may lead to cirrhosis, hepatic carcinoma and death. Ultrasound (US) shear wave elastography (SWE) is a relatively new, popular, non-invasive technique among radiologists. Although many studies have been published va...

journal_title：Physics in medicine and biology

authors： Kagadis GC,Drazinos P,Gatos I,Tsantis S,Papadimitroulas P,Spiliopoulos S,Karnabatidis D,Theotokas I,Zoumpoulis P,Hazle JD

更新日期：2020-11-05 00:00:00

abstract：:Physical properties of a position-sensitive camera for the analysis of biodistributions of gamma- and beta-emitting radiopharmaceuticals in small animals have been studied, in order to achieve optimal operating conditions. The camera consisted of a highly segmented yttrium-aluminate perovskite (YAP) scintillator, coup...

journal_title：Physics in medicine and biology

authors： Uzunov N,Bello M,Boccaccio P,Moschini G,Baldazzi G,Bollini D,de Notaristefani F,Mazzi U,Riondato M

更新日期：2005-02-07 00:00:00

abstract：:Under various clinical situations, it is desirable to modify the original treatment plan to better suit the clinical goals. In this work, a method to help physicians modify treatment plans based on their clinical preferences is proposed. The method uses a weighted quadratic dose objective function. The commonly used o...

journal_title：Physics in medicine and biology

authors： Wu C,Olivera GH,Jeraj R,Keller H,Mackie TR

更新日期：2003-08-07 00:00:00

abstract：:An algorithm for dynamic multileaf-collimator (dMLC) tracking of a target performing a known a priori, rigid-body motion during volumetric modulated arc therapy (VMAT), has been experimentally validated and applied to investigate the potential of the Agility (Elekta AB, Stockholm, Sweden) multileaf-collimator (MLC) fo...

journal_title：Physics in medicine and biology

authors： Davies GA,Clowes P,Bedford JL,Evans PM,Webb S,Poludniowski G

更新日期：2013-07-07 00:00:00

abstract：:Although physical metrics can objectively characterize computed tomography (CT) image quality, quantitative approaches to predict human observer performance are more accurate and clinically relevant. This study compared a modified channelized Hotelling model observer (CHO) with human observers in a shape discriminatio...

journal_title：Physics in medicine and biology

authors： Zhang Y,Leng S,Yu L,Carter RE,McCollough CH

更新日期：2014-07-07 00:00:00

abstract：:There are three ways to determine the spectrum of a clinical photon beam: direct measurement, modelling the source and reconstruction from ion-chamber measurements. We focus on reconstruction because the necessary equipment is readily available and it provides independent confirmation of source models for a given mach...

journal_title：Physics in medicine and biology

authors： Armbruster B,Hamilton RJ,Kuehl AK

更新日期：2004-11-21 00:00:00

abstract：:Recently, there has been a resurgence of interest in arc-based IMRT, through the use of 'conventional' multileaf collimator (MLC) systems that can treat large tumor volumes in a single, or very few pass(es) of the gantry. Here we present a novel 'burst mode' modulated arc delivery approach, wherein 2000 monitor units ...

journal_title：Physics in medicine and biology

authors： Salter BJ,Sarkar V,Wang B,Shukla H,Szegedi M,Rassiah-Szegedi P

更新日期：2011-04-07 00:00:00

abstract：:In the real-time tumor-tracking radiotherapy system, fluoroscopy is used to determine the real-time position of internal fiducial markers. The pattern recognition score (PRS) ranging from 0 to 100 is computed by a template pattern matching technique in order to determine the marker position on the fluoroscopic image. ...

journal_title：Physics in medicine and biology

authors： Miyamoto N,Ishikawa M,Bengua G,Sutherland K,Suzuki R,Kimura S,Shimizu S,Onimaru R,Shirato H

更新日期：2011-08-07 00:00:00