Abstract:
:In the real-time tumor-tracking radiotherapy system, fluoroscopy is used to determine the real-time position of internal fiducial markers. The pattern recognition score (PRS) ranging from 0 to 100 is computed by a template pattern matching technique in order to determine the marker position on the fluoroscopic image. The PRS depends on the quality of the fluoroscopic image. However, the fluoroscopy parameters such as tube voltage, current and exposure duration are selected manually and empirically in the clinical situation. This may result in an unnecessary imaging dose from the fluoroscopy or loss of the marker because of too much or insufficient x-ray exposure. In this study, a novel optimization method is proposed in order to minimize the fluoroscopic dose while keeping the image quality usable for marker tracking. The PRS can be predicted in a region where the marker appears to move in the fluoroscopic image by the proposed method. The predicted PRS can be utilized to judge whether the marker can be tracked with accuracy. In this paper, experiments were performed to show the feasibility of the PRS prediction method under various conditions. The predicted PRS showed good agreement with the measured PRS. The root mean square error between the predicted PRS and the measured PRS was within 1.44. An experiment using a motion controller and an anthropomorphic chest phantom was also performed in order to imitate a clinical fluoroscopy situation. The result shows that the proposed prediction method is expected to be applicable in a real clinical situation.
journal_name
Phys Med Bioljournal_title
Physics in medicine and biologyauthors
Miyamoto N,Ishikawa M,Bengua G,Sutherland K,Suzuki R,Kimura S,Shimizu S,Onimaru R,Shirato Hdoi
10.1088/0031-9155/56/15/011subject
Has Abstractpub_date
2011-08-07 00:00:00pages
4803-13issue
15eissn
0031-9155issn
1361-6560pii
S0031-9155(11)87555-Xjournal_volume
56pub_type
杂志文章abstract::We show that it is possible to translate an intensity modulated radiation therapy (IMRT) treatment plan and deliver it as a single arc. This technique is referred to in this paper as aperture modulation arc therapy (AMAT). During this arc, the MLC leaves do not conform to the projection of the target PTV and the machi...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/48/10/307
更新日期:2003-05-21 00:00:00
abstract::A new mathematical model of the head has been constructed from a set of serial MRI slices from one subject. Finite-difference time-domain (FDTD) calculations of the specific energy absorption rate (SAR) have been performed on this model with a 2 mm resolution for a generic mobile communication transceiver represented ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/39/10/003
更新日期:1994-10-01 00:00:00
abstract::We have developed a model using Monte Carlo methods to simulate x-ray mammography. All possible physical processes of interaction of x-rays with matter have been taken into account. A simplified geometry of the mammographic apparatus has been considered along with a software phantom of compressed breast. The phantom m...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/43/11/012
更新日期:1998-11-01 00:00:00
abstract::The aim of this work was to evaluate the accuracy of dose predicted in heterogeneous media by a pencil beam (PB), a collapsed cone (CC) and a Monte Carlo (MC) algorithm. For this purpose, a simple multi-layer phantom composed of Styrofoam and white polystyrene was irradiated with 10 x 10 cm2 as well as 20 x 20 cm2 ope...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/50/5/010
更新日期:2005-03-07 00:00:00
abstract::The influence of artefacts due to metal implants on the range of ion beams is investigated, using a geometrically well-defined head and pelvic phantom together with inserts from steel, titanium and tungsten. The ranges along various beam paths including artefacts were calculated from the TPS and compared to known calc...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/52/3/007
更新日期:2007-02-07 00:00:00
abstract::Discrete implanted liver tumours in the rat have been exposed to arrays of 1.7 MHz ultrasound lesions. Focal peak intensities in the range 1.4-3.5 k Wcm-2 were used for an exposure time of 10 s. It has been demonstrated that where the whole tumour volume was exposed to the focused ultrasound beam, no evidence of tumou...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/36/11/009
更新日期:1991-11-01 00:00:00
abstract::Amorphous silicon electronic portal imaging devices (EPIDs) are used to perform routine quality control (QC) checks on the multileaf collimators (MLCs) at this centre. Presently, these checks are performed at gantry angle 0 degrees and are considered to be valid for all other angles. Since therapeutic procedures regul...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/53/2/013
更新日期:2008-01-21 00:00:00
abstract::Managing uncertainty is a major challenge in radiation therapy treatment planning, including uncertainty induced by intrafraction motion, which is particularly important for tumours in the thorax and abdomen. Common methods to account for motion are to introduce a margin or to convolve the static dose distribution wit...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/51/10/014
更新日期:2006-05-21 00:00:00
abstract::Several studies have been appeared, up to now, that indicate the effect of accurate simulation on dose received by different substructures of the eye, irradiated by external beams of short-range radiation such as electron. Different representations of the eye have consequently been introduced. Their accuracies depend ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/1361-6560/ab2059
更新日期:2019-07-02 00:00:00
abstract::Proton therapy potentially offers excellent dose conformality and reduction in integral dose. The superior dose distribution is, however, much more sensitive to the radiological depth along the beam path than for photon fields. Variations in this depth due to inaccurate planning calculation, setup uncertainty, respira...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/53/5/016
更新日期:2008-03-07 00:00:00
abstract::We present a new version of STIR (Software for Tomographic Image Reconstruction), an open source object-oriented library implemented in C++ for 3D positron emission tomography reconstruction. This library has been designed such that it can be used for many algorithms and scanner geometries, while being portable to var...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/57/4/867
更新日期:2012-02-21 00:00:00
abstract::A non-contact approach for diffuse optical tomography (DOT) has been developed for on-demand image updates using surgical navigation technology. A stereoscopic optical tracker provides real-time localization of reflective spheres mounted to a laser diode and near-infrared camera. Standard camera calibration is combine...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/1361-6560/ab1f33
更新日期:2019-07-05 00:00:00
abstract::Micro-CT is widely used in preclinical studies, generating substantial interest in extending its capabilities in functional imaging applications such as blood perfusion and cardiac function. However, imaging cardiac structure and function in mice is challenging due to their small size and rapid heart rate. To overcome...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/1361-6560/aa9b45
更新日期:2018-01-09 00:00:00
abstract::Two different classifiers, an artificial neural network (ANN) and a hybrid system (one step rule-based method followed by an artificial neural network) have been investigated to merge computer-extracted features in the task of differentiating between malignant and benign masses. A database consisting of 65 cases (38 m...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/44/10/315
更新日期:1999-10-01 00:00:00
abstract::In this note, we present the first experimental results of in-beam PET measurements during high energy photon phantom irradiation. An inhomogeneous phantom was irradiated with pulsed 34 MV bremsstrahlung. The measurements have been conducted with a dedicated double head positron camera. A high material contrast could ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/52/20/N01
更新日期:2007-10-21 00:00:00
abstract::In proton scanning systems that employ active energy variation for depth modulation, a switch of the particle energy might typically require 1-2 s. For plans comprising many energy slices, these seconds could sum up to a non-negligible fraction of the total treatment duration. We have applied the Nyquist-Shannon sampl...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/53/9/N01
更新日期:2008-05-07 00:00:00
abstract::Over the last 50 years, diagnostic imaging has grown from a state of infancy to a high level of maturity. Many new imaging modalities have been developed. However, modern medical imaging includes not only image production but also image processing, computer-aided diagnosis (CAD), image recording and storage, and image...
journal_title:Physics in medicine and biology
pub_type: 杂志文章,评审
doi:10.1088/0031-9155/51/13/R02
更新日期:2006-07-07 00:00:00
abstract::Random coincidences can contribute substantially to the background in positron emission tomography (PET). Several estimation methods are being used for correcting them. The goal of this study was to investigate the validity of techniques for random coincidence estimation, with various low-energy thresholds (LETs). Sim...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/53/9/012
更新日期:2008-05-07 00:00:00
abstract::Treatment planning for proton tumor therapy requires a fast and accurate dose-calculation method. We have implemented a simplified Monte Carlo (SMC) method in the treatment planning system of the National Cancer Center Hospital East for the double-scattering beam delivery scheme. The SMC method takes into account the ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/55/12/018
更新日期:2010-06-21 00:00:00
abstract::The treatment of large tumors such as sarcomas with intra-operative radiotherapy using a Mobetron is often complicated because of the limited field size of the primary collimator and the available applicators (max Ø100 mm). To circumvent this limitation a prototype rectangular applicator of 80 x 150 mm(2) was designed...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/53/8/006
更新日期:2008-04-21 00:00:00
abstract::Respiratory-correlated cone-beam CT (CBCT) not only inhibits rapid scanning due to the slow speed of the LINAC head gantry rotation, but its implementation for routine patient imaging is impractical because of the high radiation dose delivered during the process. Digital tomosynthesis (DTS) is a potentially faster tec...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/1361-6560/ab0d50
更新日期:2019-05-02 00:00:00
abstract::A method to determine the spectrum of a clinical photon beam from measured depth-dose data is described. At shallow depths, where the range of Compton-generated electrons increases rapidly with photon energy, the depth dose provides the information to discriminate the spectral contributions. To minimize the influence ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/45/1/312
更新日期:2000-01-01 00:00:00
abstract::Data filtering is crucial for accurate relative stopping power (RSP) reconstruction in proton CT (pCT). In this work, we assess different filters and their performance for the US pCT collaboration prototype pCT system in Monte Carlo (MC) simulations. The potential of using the recently proposed [Formula: see text]-E f...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/1361-6560/ab2671
更新日期:2019-08-01 00:00:00
abstract::The whole prostatic volume (PV) is an important indicator for benign prostate hyperplasia. Correlating the PV with other clinical parameters in a population-based prospective cohort study (SHIP-2) requires valid prostate segmentation in a large number of whole-body MRI scans. The axial proton density fast spin echo fa...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/58/17/5899
更新日期:2013-09-07 00:00:00
abstract::The 0.35 T 60Co MRIdian system (ViewRay Inc., Mountain View) has been in clinical use in our institution since May 2016. For quality assurance (QA) of dose delivery and end-to-end testing for this machine, a reliable dosimeter is required. However, it is possible that a magnetic field may cause perturbations to dosime...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/1361-6560/aad58d
更新日期:2018-08-20 00:00:00
abstract::Simultaneous thermoradiotherapy has been shown to maximize the effect of hyperthermia as a radiation sensitizer in cancer treatment. Here we follow our previous work on feasibility of thermoradiotherapy with the scanning ultrasound reflector linear array system (SURLAS) and TomoTherapy HiArt treatment system, and inve...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/53/10/004
更新日期:2008-05-21 00:00:00
abstract::In recent years, the Monte Carlo method has been used in a large number of research studies in radiation therapy. For applications such as treatment planning, it is essential to validate the dosimetric accuracy of the Monte Carlo simulations in heterogeneous media. The AAPM Report no 105 addresses issues concerning cl...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/53/16/016
更新日期:2008-08-21 00:00:00
abstract::The bone suppression technique based on advanced image processing can suppress the conspicuity of bones on chest radiographs, creating soft tissue images obtained by the dual-energy subtraction technique. This study was performed to evaluate the usefulness of bone suppression image processing in image-guided radiation...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/60/10/n209
更新日期:2015-05-21 00:00:00
abstract::A new system has been designed and built to validate the concept of 3D computerized angiography (CA). This system can acquire a set of 2D digital subtracted angiography images while rotating around a patient and then, using these images, reconstruct a 3D representation of the opacified vasculature. The design principl...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/39/3/020
更新日期:1994-03-01 00:00:00
abstract::To replace the conventional pinhole (normal cone-beam) collimator, a novel skew-slit collimator was previously proposed and a Novikov-type algorithm developed to reconstruct images using the skew-slit geometry. The goal of this paper is to develop a reconstruction algorithm that has better noise control than the Novik...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/51/23/018
更新日期:2006-12-07 00:00:00