Monte Carlo generated mammograms: development and validation.

abstract：:Dual-energy x-ray absorptiometry (DXA) is widely applied for estimating body fat. The percentage of body mass as fat (%fat) is predicted from a DXA-estimated R(ST) value defined as the ratio of soft tissue attenuation at two photon energies (e.g., 40 keV and 70 keV). Theoretically, the R(ST) concept depends on the mas...

journal_title：Physics in medicine and biology

authors： Wang Z,Heymsfield SB,Chen Z,Zhu S,Pierson RN

更新日期：2010-05-07 00:00:00

abstract：:Spreadsheet templates which calculate cumulative exposures to other persons from patients to whom radioactive materials have been administered have been developed by the authors. Calculations can be based on any specified single-, bi- or tri-exponential whole-body clearance rate and a diurnal (or any other periodic) c...

journal_title：Physics in medicine and biology

authors： Cormack J,Shearer J

更新日期：1998-03-01 00:00:00

abstract：:The aim of this work was to evaluate the accuracy of dose predicted in heterogeneous media by a pencil beam (PB), a collapsed cone (CC) and a Monte Carlo (MC) algorithm. For this purpose, a simple multi-layer phantom composed of Styrofoam and white polystyrene was irradiated with 10 x 10 cm2 as well as 20 x 20 cm2 ope...

journal_title：Physics in medicine and biology

authors： Krieger T,Sauer OA

更新日期：2005-03-07 00:00:00

abstract：:Computer aided detection (CADe) for breast lesion can provide an important reference for radiologists in breast cancer screening. Architectural distortion (AD) is a type of breast lesion that is difficult to detect. A majority of CADe methods focus on detecting the radial pattern, which is a main characteristic of typ...

journal_title：Physics in medicine and biology

authors： Li Y,He Z,Lu Y,Ma X,Guo Y,Xie Z,Xu Z,Chen W,Chen H

更新日期：2020-06-02 00:00:00

abstract：:Oxygen ([Formula: see text]) ions are a potential alternative to carbon ions in ion beam therapy. Their enhanced linear energy transfer indicates a higher relative biological effectiveness and a reduced oxygen enhancement ratio. Due to the limited availability of [Formula: see text] ion beams, Monte Carlo (MC) transpo...

journal_title：Physics in medicine and biology

authors： Resch AF,Fuchs H,Georg D

更新日期：2017-09-05 00:00:00

abstract：:Curves relating beam energy, scattering foil thickness, central-axis depth-dose, and beam flatness have been generated using data taken on a Siemens 200A betatron. The curve set allows a single combination of tungsten foil thickness and electron beam energy to be chosen that will provide the optimum depth-dose distrib...

journal_title：Physics in medicine and biology

authors： Marbach JR,Almond PR

更新日期：1981-05-01 00:00:00

abstract：:We comment on a previous article by Zhang and Newhauser (2009 Phys. Med. Biol. 54 1383-95) which presents several approximate ways of computing the water equivalent of an arbitrary degrader. First, we present a simple exact method which depends only on the range-energy relation of water and of the degrader material. S...

journal_title：Physics in medicine and biology

authors： Gottschalk B

更新日期：2010-05-07 00:00:00

abstract：:A post-processing noise suppression technique for biomedical MRI images is presented. The described procedure recovers both sharp edges and smooth surfaces from a given noisy MRI image; it does not blur the edges and does not introduce spikes or other artefacts. The fine details of the image are also preserved. The pr...

journal_title：Physics in medicine and biology

authors： Placidi G,Alecci M,Sotgiu A

更新日期：2003-07-07 00:00:00

abstract：:In this paper, Novikov's inversion formula of the attenuated two-dimensional (2D) Radon transform is applied to the reconstruction of attenuated fan-beam projections acquired with equal detector spacing and of attenuated cone-beam projections acquired with a flat planar detector and circular trajectory. The derivation...

journal_title：Physics in medicine and biology

authors： Huang Q,Zeng GL,You J,Gullberg GT

更新日期：2005-05-21 00:00:00

abstract：:In recent years there has been a large amount of research into the potential use of radiation sensitive gels for three-dimensional verification of clinical radiotherapy doses. In this paper we report the use of a MAGIC gel dosimeter (Fong et al 2001 Phys. Med. Biol. 46 3105) for the verification of a specific patient'...

journal_title：Physics in medicine and biology

authors： Trapp JV,Partridge M,Hansen VN,Childs P,Bedford J,Warrington AP,Leach MO,Webb S

更新日期：2004-05-07 00:00:00

abstract：:Heavy-ion radiotherapy exploits the high biological effectiveness of localized energy deposition delivered by so-called Bragg-peak particles. Recent publications have challenged the established procedures to calculate biological effective dose distributions in treatment planning. They emphasize the importance of very ...

journal_title：Physics in medicine and biology

authors： Elsässer T,Gemmel A,Scholz M,Schardt D,Krämer M

更新日期：2009-04-07 00:00:00

abstract：:A method for quantifying the tissue sodium concentration (TSC) in the rat brain from ²³Na-MR images was developed. TSC is known to change in a variety of common human diseases and holds considerable potential to contribute to their study; however, its accurate measurement in small laboratory animals has been hindered ...

journal_title：Physics in medicine and biology

authors： Wetterling F,Tabbert M,Junge S,Gallagher L,Macrae IM,Fagan AJ

更新日期：2010-12-21 00:00:00

abstract：:Within an epidemiological study regarding the correlation between skin pathologies and personal ultraviolet (UV) exposure due to solar radiation, 14 field campaigns using polysulphone (PS) dosemeters were carried out at three different Italian sites (urban, semi-rural and rural) in every season of the year. A polysulp...

journal_title：Physics in medicine and biology

authors： Casale GR,Borra M,Colosimo A,Colucci M,Militello A,Siani AM,Sisto R

更新日期：2006-09-07 00:00:00

abstract：:K-edge subtraction (KES) imaging is a technique able to map a specific element such as e.g. a contrast agent within the tissues, by exploiting the sharp rise of its absorption coefficient at the K-edge energy. Whereas mainly explored at synchrotron radiation sources, the energy discrimination properties of modern x-ra...

journal_title：Physics in medicine and biology

authors： Brun F,Di Trapani V,Albers J,Sacco P,Dreossi D,Brombal L,Rigon L,Longo R,Mittone A,Dullin C,Bravin A,Delogu P

更新日期：2020-03-06 00:00:00

abstract：:For plane-parallel chambers used in electron dosimetry, modern dosimetry protocols recommend a cross-calibration against a calibrated cylindrical chamber. The rationale for this is the unacceptably large (up to 3-4%) chamber-to-chamber variations of the perturbation factors (pwall)Co, which have been reported for plan...

journal_title：Physics in medicine and biology

authors： Kapsch RP,Bruggmoser G,Christ G,Dohm OS,Hartmann GH,Schüle E

更新日期：2007-12-07 00:00:00

abstract：:A simple and fast, but sensitive TLD method for the measurement of energy and homogeneity of therapeutically used electron beams has been developed and tested. This method is based on the fact that when small thicknesses of high-Z absorbers such as lead are interposed in the high-energy electron beams, the transmitted...

journal_title：Physics in medicine and biology

authors： Pradhan AS,Quast U,Sharma PK

更新日期：1994-09-01 00:00:00

abstract：:Margins are employed in radiotherapy treatment planning to mitigate the dosimetric effects of geometric uncertainties for the clinical target volume (CTV). Unfortunately, whilst the use of margins can increase the probability that sufficient dose is delivered to the CTV, it can also result in delivering high dose of r...

journal_title：Physics in medicine and biology

authors： Tsang HS,Kamerling CP,Ziegenhein P,Nill S,Oelfke U

更新日期：2018-10-29 00:00:00

abstract：:In this letter the authors highlight the presence of an error appearing in the discussion of the note 'The use of the Henyey-Greenstein phase function in Monte Carlo simulations in biomedical optics' previously published by them (Binzoni et al 2006 Phys. Med. Biol. 51 N313). In the light of this error, the discussion ...

journal_title：Physics in medicine and biology

authors： Binzoni T,Leung TS,Gandjbakhche AH,Rüfenacht D,Delpy DT

更新日期：2006-11-21 00:00:00

abstract：:Radionuclides which decay by electron capture accompanied by Auger electron cascades, or by beta emission are thought to be excessively damaging when incorporated into the molecular structure of mammalian cell nuclei and thereby pose a radiation hazard which is not assessable by conventional dosimetry. Survival data, ...

journal_title：Physics in medicine and biology

authors： Younis AR,Watt DE

更新日期：1989-07-01 00:00:00

abstract：:Doxorubicin (Dox) is a well-established chemotherapeutic agent, however it has limited efficacy in treating brain malignancies due to the presence of the blood-brain barrier (BBB). Recent preclinical studies have demonstrated that focused ultrasound induced BBB disruption (BBBD) enables efficient delivery of Dox to th...

journal_title：Physics in medicine and biology

authors： Nhan T,Burgess A,Lilge L,Hynynen K

更新日期：2014-10-21 00:00:00

abstract：:In the IAEA-AAPM dosimetry formalism, detector measurements in general nonstandard conditions are corrected using the factor k(f(clin),f(msr))(Q(clin),Q(msr)). This factor needs to be evaluated on a case-by-case basis which is difficult to accomplish in practice. The present paper aims to provide a method that allows ...

journal_title：Physics in medicine and biology

authors： Kamio Y,Bouchard H

更新日期：2014-09-07 00:00:00

abstract：:In charged particle therapy with pencil beam scanning (PBS), localization of the dose in the Bragg peak makes dose distributions sensitive to lateral tissue heterogeneities. The sensitivity of a PBS plan to lateral tissue heterogeneities can be reduced by selecting appropriate beam angles. The purpose of this study is...

journal_title：Physics in medicine and biology

authors： Toramatsu C,Inaniwa T

更新日期：2016-12-21 00:00:00

abstract：:An algorithm for dynamic multileaf-collimator (dMLC) tracking of a target performing a known a priori, rigid-body motion during volumetric modulated arc therapy (VMAT), has been experimentally validated and applied to investigate the potential of the Agility (Elekta AB, Stockholm, Sweden) multileaf-collimator (MLC) fo...

journal_title：Physics in medicine and biology

authors： Davies GA,Clowes P,Bedford JL,Evans PM,Webb S,Poludniowski G

更新日期：2013-07-07 00:00:00

abstract：:For PET online data acquisition, a centralized coincidence processor (CCP) with a single-thread data processing has been used to select coincidence events for many PET scanners. CCP has the advantage of highly integrated circuit, compact connection between detector front-end and system electronics, and centralized con...

journal_title：Physics in medicine and biology

authors： Cheng X,Hu K,Yang D,Shao Y

更新日期：2021-01-21 00:00:00

abstract：:The influence of artefacts due to metal implants on the range of ion beams is investigated, using a geometrically well-defined head and pelvic phantom together with inserts from steel, titanium and tungsten. The ranges along various beam paths including artefacts were calculated from the TPS and compared to known calc...

journal_title：Physics in medicine and biology

authors： Jäkel O,Reiss P

更新日期：2007-02-07 00:00:00

abstract：:The UK and European protocols for mammographic dosimetry use conversion factors that relate incident air kerma to the mean glandular dose (MGD) within the breast. The conversion factors currently used were obtained by computer simulation of a model breast with a composition of 50% adipose and 50% glandular tissues by ...

journal_title：Physics in medicine and biology

authors： Dance DR,Skinner CL,Young KC,Beckett JR,Kotre CJ

更新日期：2000-11-01 00:00:00

abstract：:We have investigated the tongue-and-groove effect on the IMRT dose distributions for a Varian MLC. We have compared the dose distributions calculated using the intensity maps with and without the tongue-and-groove effect. Our results showed that, for one intensity-modulated treatment field, the maximum tongue-and-groo...

journal_title：Physics in medicine and biology

authors： Deng J,Pawlicki T,Chen Y,Li J,Jiang SB,Ma CM

更新日期：2001-04-01 00:00:00

abstract：:Dose measurements following 10 min irradiations with a portable x-ray fluorescence spectrometer composed of a miniature x-ray tube and a silicon PiN diode detector were performed using thermoluminescent dosimeters consisting of LiF:Mg,Ti chips of 3 mm diameter and 0.4 mm thickness. The table-top setup of the spectrome...

journal_title：Physics in medicine and biology

authors： Gherase MR,Mader JE,Fleming DE

更新日期：2010-09-21 00:00:00

abstract：:An alternative to gamma (gamma) histograms for ROI-based quantitative comparisons of dose distributions using the gamma concept is proposed. The method provides minimum values of dose difference and distance-to-agreement such that a pre-set fraction of the region of interest passes the gamma test. Compared to standard...

journal_title：Physics in medicine and biology

authors： Dvorak P

更新日期：2009-06-21 00:00:00

abstract：:This study was carried out to investigate whether the electronic portal imaging (EPI) acquisition process could be optimized, and as a result tolerance and action levels be set for the PIPSPro QC-3V phantom image quality assessment. The aim of the optimization process was to reduce the dose delivered to the patient wh...

journal_title：Physics in medicine and biology

authors： McGarry CK,Grattan MW,Cosgrove VP

更新日期：2007-12-07 00:00:00